scholarly journals Antimicrobial activity, cytotoxicity and chemical analysis of lemongrass essential oil (Cymbopogon flexuosus) and pure citral

2016 ◽  
Vol 100 (22) ◽  
pp. 9619-9627 ◽  
Author(s):  
Emmanuel C. Adukwu ◽  
Melissa Bowles ◽  
Valerie Edwards-Jones ◽  
Heather Bone
Keyword(s):  
Antimicrobial Activity ◽  
Chemical Analysis ◽  
Essential Oil ◽  
Cymbopogon Flexuosus ◽  
Lemongrass Essential Oil

scholarly journals Antimicrobial Activity of Lemongrass Essential Oil (Cymbopogon flexuosus) and Its Active Component Citral Against Dual-Species Biofilms of Staphylococcus aureus and Candida Species

2020 ◽  
Vol 10 ◽  
Author(s):  
Shanjun Gao ◽  
Guangzhi Liu ◽  
Jianguo Li ◽  
Jing Chen ◽  
Lina Li ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Essential Oil ◽  
Pathogenic Bacteria ◽  
Expression Of Genes ◽  
Cymbopogon Flexuosus ◽  
Underlying Mechanisms ◽  
Bacteria And Fungi ◽  
Conventional Antibiotics ◽  
Lemongrass Essential Oil

Compared to mono-species biofilm, biofilms formed by cross-kingdom pathogens are more refractory to conventional antibiotics, thus complicating clinical treatment and causing significant morbidity. Lemongrass essential oil and its bioactive component citral were previously demonstrated to possess strong antimicrobial efficacy against pathogenic bacteria and fungi. However, their effects on polymicrobial biofilms remain to be determined. In this study, the efficacy of lemongrass (Cymbopogon flexuosus) essential oil and its bioactive part citral against dual-species biofilms formed by Staphylococcus aureus and Candida species was evaluated in vitro. Biofilm staining and viability test showed both lemongrass essential oil and citral were able to reduce biofilm biomass and cell viability of each species in the biofilm. Microscopic examinations showed these agents interfered with adhesive characteristics of each species and disrupted biofilm matrix through counteracting nucleic acids, proteins and carbohydrates in the biofilm. Moreover, transcriptional analyses indicated citral downregulated hyphal adhesins and virulent factors of Candida albicans, while also reducing expression of genes involved in quorum sensing, peptidoglycan and fatty acids biosynthesis of S. aureus. Taken together, our results demonstrate the potential of lemongrass essential oil and citral as promising agents against polymicrobial biofilms as well as the underlying mechanisms of their activity in this setting.

scholarly journals Chemical composition, antimicrobial and antifungal activity of Lippia Thymoide essential oil in oral pathogens

2021 ◽  
Vol 20 ◽  
pp. e210219
Author(s):  
Tabata Resque Beckmann Carvalho ◽  
Erich Brito Tanaka ◽  
Amujacy Tavares Vilhena ◽  
Paula Cristina Rodrigues Frade ◽  
Ricardo Roberto de Souza Fonseca ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Chemical Composition ◽  
Chemical Analysis ◽  
Essential Oil ◽  
Antimicrobial Agents ◽  
Fusobacterium Nucleatum ◽  
Triphenyltetrazolium Chloride ◽  
Gram Negative ◽  
Main Compound ◽  
Bacteria And Fungi

Aim: This study evaluated the chemical composition of Lippia thymoides (Lt) essential oil and its antimicrobial activity against fungal strains of Candida albicans (Ca) and Gram-negative bacteria Prevotella intermedia (Pi) and Fusobacterium nucleatum (Fn). Methods: Lt essential oil was obtained by hydrodistillation apparatus with a modified Clevenger extension. The chemical analysis was analyzed by gas phase chromatography and mass spectrometry on Shimadzu QP 2010 plus. Sample sensitivity evaluation was performed by ABHb-inoculum and culture plates were developed with triphenyltetrazolium chloride, also Fn and Pi samples analysis were in anaerobic environment and Ca sample analysis was performed in aerobic environment. The minimum inhibitory concentration (CIM) was determinated by microdilution in eppendorfs tubes. Results: The chemical analysis showed that Thymol (59,91%) is the main compound found in Lt essential oil, also other antifungal and antimicrobial agents were present γ-terpinene (8.16%), p-cymene (7.29%) and β-caryophyllene (4.49%), Thymol is a central ingredient of many medicinal plants and has a potent fungicidal, bactericidal and antioxidant activity, it has been previously shown to have anti-inflammatory activity against Periodontal Disease (PD) cause can reduces prostanoids, interleukins, leukotrienes levels in periodontium. CIM result Pi was 6.5 μg/mL, Fn was 1.5 μg/mL and Ca was 0.19 μg/mL. Conclusion: The antimicrobial activity of L. thymoides, through the compound Thymol, has been shown promising potential against gram-negative periodontopathogenic bacteria and fungi whose therapeutic arsenal is still very restricted.

scholarly journals Chemical analysis and antimicrobial activity of essential oil extracted from Helichrysum aureonitens

2005 ◽  
Vol 71 (2) ◽  
pp. 250-252 ◽  
Author(s):  
V.V. Yani ◽  
O.A. Oyedeji ◽  
D.S. Grierson ◽  
A.J. Afolayan
Keyword(s):  
Antimicrobial Activity ◽  
Chemical Analysis ◽  
Essential Oil

Antimicrobial activity and physical properties of starch/chitosan film incorporated with lemongrass essential oil and its application

LWT ◽  
2021 ◽  
Vol 141 ◽  
pp. 110934
Author(s):  
Muhammad Iqbal Perdana ◽  
Jareerat Ruamcharoen ◽  
Somrak Panphon ◽  
Montira Leelakriangsak
Keyword(s):  
Antimicrobial Activity ◽  
Essential Oil ◽  
Physical Properties ◽  
Chitosan Film ◽  
Lemongrass Essential Oil

scholarly journals Biosynthesis of Lemongrass Essential Oil and the Underlying Mechanism for Its Insecticidal Activity

2020 ◽  
Author(s):  
Mohammad Mukarram ◽  
M. Masroor A. Khan ◽  
Andleeb Zehra ◽  
Sadaf Choudhary ◽  
Tariq Aftab ◽  
...  
Keyword(s):  
Essential Oil ◽  
Synergistic Effects ◽  
Biological Activities ◽  
Perennial Grass ◽  
Underlying Mechanism ◽  
Cymbopogon Flexuosus ◽  
Anti Cancer ◽  
Lemongrass Oil ◽  
Cytotoxic Responses ◽  
Lemongrass Essential Oil

Lemongrass (Cymbopogon flexuosus) is an aromatic perennial grass grown extensively for its essential oil. Lemongrass oil is chiefly a mixture of various cyclic and acyclic bioactive monoterpenes. We reviewed lemongrass oil and its biosynthesis in the present chapter along with its biochemical composition. Furthermore, we attempted to explore both the possible routes for essential oil biosynthesis in lemongrass, i.e. mevalonate and non-mevalonate pathways and how these pathways interwind with each other. Lemongrass oil has high commercial potential in medicinal, cosmetic, food and energy industries. Regarding the pharmacological properties, a wide array of biological activities has been observed in lemongrass oil such as antimicrobial, insecticidal, analgesic and anti-cancer properties as well as its efficacy as insect-repellent. The later sections were dedicated for the analysis of insecticidal property of the lemongrass oil and the mechanism working behind this phenomenon where it was observed that in addition to synergistic effects, various components of lemongrass oil can also induce specific neurotoxic and cytotoxic responses in the insects.

scholarly journals Antimicrobial Activity of Cymbopogon Citratus (Dc) Stapf (Lemongrass) Essential Oil on Pathogenic Bacteria From Fruit Juices

2014 ◽  
Author(s):  
Caroline Junqueira Barcellos Leite ◽  
Jossana Pereira de Sousa ◽  
Kataryne Árabe Rimá de Oliveira ◽  
Geany Targino de Souza ◽  
Danilo Elias Xavier ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Essential Oil ◽  
Pathogenic Bacteria ◽  
Fruit Juices ◽  
Cymbopogon Citratus ◽  
Lemongrass Essential Oil

Chemical Analysis and Antimicrobial Activity of the Resin Ladano, of its Essential Oil and of the Isolated Compounds**

Planta Medica ◽  
1999 ◽  
Vol 65 (01) ◽  
pp. 76-78 ◽  
Author(s):  
Costas Demetzos ◽  
Berthamarie Stahl ◽  
Thalia Anastassaki ◽  
Maria Gazouli ◽  
Leonidas Tzouvelekis ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Chemical Analysis ◽  
Essential Oil

scholarly journals Cosmetic bio-product based on cinnamon essential oil “Cinnamomum verum” for the treatment of mycoses: preparation, chemical analysis and antimicrobial activity

2019 ◽  
Vol 5 (1) ◽  
pp. 5-8
Author(s):  
Tarik Ainane ◽  
Fatima Khammour ◽  
Nawal Merghoub ◽  
Meriem Elabboubi ◽  
Sanaa Charaf ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Chemical Analysis ◽  
Essential Oil ◽  
Cinnamon Essential Oil

scholarly journals ANTIMICROBIAL PROPERTIES OF RABBIT COLLAGEN GLUE-CHITOSAN BIOMATERIAL LOADED WITH CYMBOPOGON FLEXUOSUS ESSENTIAL OIL

2021 ◽  
Vol 2021 ◽  
pp. 385-390
Author(s):  
M. Râpă ◽  
M.D. Berechet ◽  
C. Gaidău ◽  
R.R. Constantinescu ◽  
A. Moșuțiu
Keyword(s):  
Wound Healing ◽  
Essential Oil ◽  
Wound Dressing ◽  
Antimicrobial Agents ◽  
Antimicrobial Properties ◽  
Natural Polymers ◽  
Cymbopogon Flexuosus ◽  
Dressing Materials ◽  
Lemongrass Essential Oil ◽  
Wound Dressing Materials

One approach to develop innovative antimicrobial wound dressing materials is to use natural polymers loaded with antimicrobial agents. The valorisation of animal proteins as biomaterials with antimicrobial properties is a new concern for development of wound healing. Plant esssential oils (EO) also indicate a potential approach for new wound dressing materials able to replace the synthetic antymicrobial agents. In this paper, plant-polymeric film was prepared by casting film-forming emulsion based on lemongrass (Cymbopogon flexuosus) essential oil/Tween 80 dispersed into rabbit collagen glue hydrolysate– chitosan biomaterial. The effect of biomaterial film composition on Staphylococcus aureus ATCC 6538 and Escherichia coli ATCC 10536 standard bacteria, and Candida albicans ATCC 10231 pathogenic fungus was studied according to European Pharmacopoeia 10/2020 as compared with biomaterial film without essential oil. The in vitro antibacterial tests against three bacterial strains showed that the rabbit collagen glue hydrolysate–chitosan biomaterial inhibited all the three microorganisms. The rabbit collagen hydrolysate glue-chitosan film loaded with lemongrass essential oil exhibits antimicrobial activity towards tested microorganisms but lower as compared with control. The explanation could be due to the short time of investigation, or maybe some active compounds constituents of EO, which favour the cellular proliferation. Preparation of rabbit collagen glue hydrolysate-chitosan biomaterial loaded with lemongrass essential oil is an environmentally friendly solution, which may contribute to the development of wound healing materials as an alternative to topical antimicrobial agents.

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