scholarly journals ANTIMICROBIAL PROPERTIES OF RABBIT COLLAGEN GLUE-CHITOSAN BIOMATERIAL LOADED WITH CYMBOPOGON FLEXUOSUS ESSENTIAL OIL

2021 ◽  
Vol 2021 ◽  
pp. 385-390
Author(s):  
M. Râpă ◽  
M.D. Berechet ◽  
C. Gaidău ◽  
R.R. Constantinescu ◽  
A. Moșuțiu
Keyword(s):  
Wound Healing ◽  
Essential Oil ◽  
Wound Dressing ◽  
Antimicrobial Agents ◽  
Antimicrobial Properties ◽  
Natural Polymers ◽  
Cymbopogon Flexuosus ◽  
Dressing Materials ◽  
Lemongrass Essential Oil ◽  
Wound Dressing Materials

One approach to develop innovative antimicrobial wound dressing materials is to use natural polymers loaded with antimicrobial agents. The valorisation of animal proteins as biomaterials with antimicrobial properties is a new concern for development of wound healing. Plant esssential oils (EO) also indicate a potential approach for new wound dressing materials able to replace the synthetic antymicrobial agents. In this paper, plant-polymeric film was prepared by casting film-forming emulsion based on lemongrass (Cymbopogon flexuosus) essential oil/Tween 80 dispersed into rabbit collagen glue hydrolysate– chitosan biomaterial. The effect of biomaterial film composition on Staphylococcus aureus ATCC 6538 and Escherichia coli ATCC 10536 standard bacteria, and Candida albicans ATCC 10231 pathogenic fungus was studied according to European Pharmacopoeia 10/2020 as compared with biomaterial film without essential oil. The in vitro antibacterial tests against three bacterial strains showed that the rabbit collagen glue hydrolysate–chitosan biomaterial inhibited all the three microorganisms. The rabbit collagen hydrolysate glue-chitosan film loaded with lemongrass essential oil exhibits antimicrobial activity towards tested microorganisms but lower as compared with control. The explanation could be due to the short time of investigation, or maybe some active compounds constituents of EO, which favour the cellular proliferation. Preparation of rabbit collagen glue hydrolysate-chitosan biomaterial loaded with lemongrass essential oil is an environmentally friendly solution, which may contribute to the development of wound healing materials as an alternative to topical antimicrobial agents.

scholarly journals Chitosan as a Wound Dressing Starting Material: Antimicrobial Properties and Mode of Action

2019 ◽  
Vol 20 (23) ◽  
pp. 5889 ◽  
Author(s):  
Matica ◽  
Aachmann ◽  
Tøndervik ◽  
Sletta ◽  
Ostafe
Keyword(s):  
Wound Healing ◽  
Wound Dressing ◽  
Antimicrobial Agents ◽  
Healing Process ◽  
Antimicrobial Properties ◽  
Starting Material ◽  
Wound Dressings ◽  
Current Status ◽  
Natural Polymers ◽  
Promising Source

Fighting bacterial resistance is one of the concerns in modern days, as antibiotics remain the main resource of bacterial control. Data shows that for every antibiotic developed, there is a microorganism that becomes resistant to it. Natural polymers, as the source of antibacterial agents, offer a new way to fight bacterial infection. The advantage over conventional synthetic antibiotics is that natural antimicrobial agents are biocompatible, non-toxic, and inexpensive. Chitosan is one of the natural polymers that represent a very promising source for the development of antimicrobial agents. In addition, chitosan is biodegradable, non-toxic, and most importantly, promotes wound healing, features that makes it suitable as a starting material for wound dressings. This paper reviews the antimicrobial properties of chitosan and describes the mechanisms of action toward microbial cells as well as the interactions with mammalian cells in terms of wound healing process. Finally, the applications of chitosan as a wound-dressing material are discussed along with the current status of chitosan-based wound dressings existing on the market.

scholarly journals Effects of wound dressing materials in combination with hyperbaric oxygen on chronic wound healing

2014 ◽  
Vol 56 (3) ◽  
pp. 164
Author(s):  
Kemal Simsek ◽  
Abdul Yapici ◽  
Hakan Cermik ◽  
Muzaffer Durmus ◽  
Mehmet Ozler ◽  
...  
Keyword(s):  
Wound Healing ◽  
Hyperbaric Oxygen ◽  
Wound Dressing ◽  
Chronic Wound ◽  
Dressing Materials ◽  
Wound Dressing Materials

scholarly journals Developmental prospectives of new generation super absorbent wound dressing materials from sulfated polysaccharide of marine red algae

2021 ◽  
Vol 23 (09) ◽  
pp. 400-408
Author(s):  
Amruth P ◽  
◽  
Amruth P ◽  
Rosemol Jacob M ◽  
Suseela Mathew ◽  
...  
Keyword(s):  
Wound Dressing ◽  
Antimicrobial Agents ◽  
Wound Care ◽  
Healing Process ◽  
Cost Effective ◽  
Sulfated Polysaccharide ◽  
Wound Dressings ◽  
New Generation ◽  
Dressing Materials ◽  
Wound Dressing Materials

Wound healing remains as a dynamic process and the type of dressing material significantly affects the efficacy of healing. The identification of ideal dressings to use for a particular wound type is an important requisite facilitating the entire process of healing. Chronic, high exudate wounds are dynamic in presentation and remain as a major health care burden. Researchers have sort to design and optimize biodegradable wound dressings that focuses to optimize moisture retentiveness, as superior character in the healing process. In addition, dressings have been designed to visualize the wound bed by improving the optical property, target and kill infection-causing bacteria, with the incorporation of antimicrobial agents, nanomaterials and numerous other measures. For the practitioners, choosing the optimal dressing decreases time to healing, provides cost-effective care and improves patient quality of life. The current mini review highlights the ideal characters of wound dressing materials and presents insights on the superior characters of carrageenan bio composites for prospective advancements in research in the area of wound care and management.

Effect of the Nano-SiO2 Particles in Gelatin and Chitosan Based Wound Dressing Materials on the Antimicrobial Effects

2014 ◽  
Vol 1002 ◽  
pp. 105-110
Author(s):  
Li Bo Wang ◽  
Xiao Yang Liu ◽  
Jun Wei ◽  
Hong Jiang
Keyword(s):  
Water Vapor ◽  
Water Uptake ◽  
Wound Dressing ◽  
Antimicrobial Agents ◽  
Binding Capacity ◽  
Antimicrobial Effect ◽  
Barrier Property ◽  
Uptake Ratio ◽  
Dressing Materials ◽  
Wound Dressing Materials

Wound dressing materials were obtained from gelatin, chitosan and nanoSiO2particles as filler. The barrier property to water vapor, water uptake ratio and antimicrobial properties of the wound dressing materials were investigated. The addition of the nanoSiO2particles endowed the materials good water uptake ratio and the barrier property to water vapor, whereas the antimicrobial agents improve the barrier property producing more hydrogen bonds. Moreover, the networks of the wound dressing materials with nanoSiO2particles displayed excellent compound binding capacity could reduce the permeation of water and increase the antimicrobial effect of the materials. The antimicrobial agents endowed the wound dressing materials with antimicrobial effect.

Advances and impact of arginine based materials in wound healing

2021 ◽  
Author(s):  
Yang Zhou ◽  
Guiting Liu ◽  
Hai Huang ◽  
Jun Wu
Keyword(s):  
Wound Healing ◽  
Wound Dressing ◽  
Bioactive Materials ◽  
Accelerate Wound Healing ◽  
Bioactive Component ◽  
Dressing Materials ◽  
Wound Dressing Materials

In studies on wound dressing materials, bioactive materials have been developed rapidly to accelerate wound healing. In recent years, scientists have studied arginine as a bioactive component due to its...

Electrospinning nanofibrous graft preparation and wound healing studies using ZnO nanoparticles and glucosamine loaded with poly(methyl methacrylate)/polyethylene glycol

2021 ◽  
Author(s):  
Suganya Bharathi Balakrishnan ◽  
Manawwer Alam ◽  
Naushad Ahmad ◽  
Manikandan Govindasamy ◽  
Sakthivelu Kuppu ◽  
...  
Keyword(s):  
Wound Healing ◽  
Polyethylene Glycol ◽  
Zno Nanoparticles ◽  
Wound Dressing ◽  
Antioxidant Properties ◽  
Wound Dressings ◽  
Nanofibrous Scaffolds ◽  
Successful Technique ◽  
Dressing Materials ◽  
Wound Dressing Materials

As wound dressing materials, electrospun nanofibrous scaffolds have a lot of promise. Electrospun nanofibrous scaffolds in combination with ZnO nanoparticles have antimicrobial and antioxidant properties, making electrospinning a successful technique for wound dressings.

scholarly journals Nanotechnology Development for Formulating Essential Oils in Wound Dressing Materials to Promote the Wound-Healing Process: A Review

2021 ◽  
Vol 11 (4) ◽  
pp. 1713
Author(s):  
Ilenia De Luca ◽  
Parisa Pedram ◽  
Arash Moeini ◽  
Pierfrancesco Cerruti ◽  
Gianfranco Peluso ◽  
...  
Keyword(s):  
Wound Healing ◽  
Essential Oils ◽  
Wound Dressing ◽  
Healing Process ◽  
Wound Dressings ◽  
Wound Healing Process ◽  
Efficient Treatment ◽  
Anti Inflammatory ◽  
Dressing Materials ◽  
Wound Dressing Materials

Wound healing refers to the replacement of damaged tissue through strongly coordinated cellular events. The patient’s condition and different types of wounds complicate the already intricate healing process. Conventional wound dressing materials seem to be insufficient to facilitate and support this mechanism. Nanotechnology could provide the physicochemical properties and specific biological responses needed to promote the healing process. For nanoparticulate dressing design, growing interest has focused on natural biopolymers due to their biocompatibility and good adaptability to technological needs. Polysaccharides are the most common natural biopolymers used for wound-healing materials. In particular, alginate and chitosan polymers exhibit intrinsic antibacterial and anti-inflammatory effects, useful for guaranteeing efficient treatment. Recent studies highlight that several natural plant-derived molecules can influence healing stages. In particular, essential oils show excellent antibacterial, antifungal, antioxidant, and anti-inflammatory properties that can be amplified by combining them with nanotechnological strategies. This review summarizes recent studies concerning essential oils as active secondary compounds in polysaccharide-based wound dressings.

Construction of cellulose nanofibers/quaternized chitin/organic rectorite composites and their application as wound dressing materials

2019 ◽  
Vol 7 (6) ◽  
pp. 2571-2581 ◽  
Author(s):  
Huimin Gao ◽  
Zibiao Zhong ◽  
Haoyang Xia ◽  
Qianchao Hu ◽  
Qifa Ye ◽  
...  
Keyword(s):  
Wound Healing ◽  
Wound Dressing ◽  
Cellulose Nanofibers ◽  
Promote Wound Healing ◽  
Dressing Materials ◽  
Wound Dressing Materials

The sponge constructed of cellulose nanofibers, quaternized chitin and organic rectorite can effectively promote wound healing.

Cerium-oxide-loaded poly(ɛ-caprolactone) hydrogel wound dressing for cutaneous wound healing and antimicrobial treatment in burn wound infection: Development and detailed biological evaluation

2021 ◽  
Vol 11 (12) ◽  
pp. 1966-1974
Author(s):  
Wei Wei ◽  
Liang Xing ◽  
Jianke Feng
Keyword(s):  
Wound Healing ◽  
Wound Dressing ◽  
Care Management ◽  
Metal Oxide Nanoparticles ◽  
Healing Process ◽  
Biological Evaluation ◽  
Cutaneous Wound Healing ◽  
Cutaneous Wound ◽  
Dressing Materials ◽  
Wound Dressing Materials

Wound dressing materials are essential in wound healing care management. In addition to their supportive effect on the care management, polysaccharides and metal oxide nanoparticles actively contribute to the healing process. CeO2 nanoparticles can promote wound healing through oxidative damage in the wound environment against elevated levels of reactive oxygen species. Therefore, it is necessary to develop multi-functional hydrogel wound dressing materials to stimulate wound healing. In this study, a CeO2-loaded poly(ɛ-caprolactone)/PEC polymeric hydrogel was fabricated as a cutaneous wound-healing material. The in-vitro cytotoxic and wound healing activities were analyzed using the fabricated material in mice. A histological examination showed that the nanofibrous material accelerated the reepithelialization and provided an excellent collagen deposition. In addition, the prepared hydrogels were tested against S. aureus and E. coli. Our results evidence the unique characteristics of the hydrogel wound dressing material exhibiting antibacterial and antioxidant activities and good biocompatibility and healing efficiencies by enhancing the reepithelialization and granulation formation and effectively accelerating the wound healing to prevent skin infections.

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