Anxiety disorders and physical comorbidity: increased prevalence but reduced relevance of specific risk factors for hospital-based mortality during a 12.5-year observation period in general hospital admissions

2014 ◽  
Vol 265 (5) ◽  
pp. 387-398 ◽  
Author(s):  
Dieter Schoepf ◽  
Reinhard Heun
Keyword(s):  
Risk Factors ◽  
Anxiety Disorders ◽  
General Hospital ◽  
Hospital Admissions ◽  
Specific Risk ◽  
Observation Period

Descriptive epidemiology of depressive and anxiety disorders, cognitive impairment and dementia in a sample of elderly patients in the geriatric unity of a general hospital

2016 ◽  
Vol 33 (S1) ◽  
pp. S177-S178
Author(s):  
A. Pater ◽  
Y. Espolio Desbaillet ◽  
D. Peris
Keyword(s):  
Risk Factors ◽  
Anxiety Disorders ◽  
Elderly Patients ◽  
General Hospital ◽  
Potential Risk ◽  
Depression Scale ◽  
Functional Independence ◽  
High Prevalence ◽  
Potential Risk Factors ◽  
Age Range

IntroductionStudies have demonstrated the high prevalence of depressive disorders amongst elderly people and their underestimation and mistreatment.ObjectiveThe aim of this study is to describe epidemiological issues in a sample of elderly hospitalized patients, giving special attention on the prevalence of depressive and anxiety disorders and the detection of potential risk factors.Material and methodsThe sample included 168 elderly patients referred for the geriatric unit of a general hospital. Epidemiological and clinical data were collected. Geriatric Depression Scale (GDS), Mini Mental State Examination (MMSE) and Functional Independence Measure (FIM™) were used. Data were analyzed with XLSTAT program.ResultsThe 39% of the sample were men and the 61% women, with an age range between 65 and 95 years. Nine percent of patients aged 65–84 had a diagnosis of depressive or anxious-depressive disorder, compared to 13% within the age range 85–95. However, 14% of patients aged 65–85 had a GDS higher than 5 and 19% for the patients aged 85–95, which could confirm the underestimated rate of depression diagnosed in elderly patients. Item “feeling loneliness” was pointed out in 75% and item “feeling bored” in 64% of all GDS higher than 5. Prevalence of dementia was 8% in the whole sample.ConclusionsHigh prevalence of depressive and anxious disorders amongst the elderly is to be taken in account. Potential risk factors could be loneliness and lack of daily activity. The development of social primary prevention interventions in order to decrease the prevalence of these pathologies amongst elderly is needed.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals The point-prevalence of alcohol use disorders and binge drinking in an Irish general hospital

2006 ◽  
Vol 23 (1) ◽  
pp. 17-20 ◽  
Author(s):  
Guy J Molyneux ◽  
Elizabeth Cryan ◽  
Elisa Dooley
Keyword(s):  
Risk Factors ◽  
Alcohol Use ◽  
Binge Drinking ◽  
General Hospital ◽  
Alcohol Use Disorder ◽  
Hospital Admissions ◽  
Adult Population ◽  
Alcohol Use Disorders ◽  
Point Prevalence ◽  
University Teaching

AbstractObjectives: There is a paucity of data concerning the prevalence of alcohol use disorders and binge drinking in the general hospital adult population in Ireland. We therefore examined the point-prevalence of alcohol use disorders and of binge drinking in the adult inpatient population of the acute wards of an Irish university teaching hospital. The secondary aim was to examine gender, age, and patient group (medical/surgical) as risk factors.Method: We administered the Alcohol Use Disorders Identification Test (AUDIT) to all consenting patients (n = 126) on the acute adult medical and surgical wards over one day.Results: 76% of all inpatients on the acute medical and surgical wards were interviewed (n = 126) using the AUDIT.Of the subjects 28% screened positive for an alcohol use disorder. Of these 91% were identified as binge drinkers.A further 8% of the subjects screened positive for binge drinking but were not identified as having an alcohol use disorder.Overall, 36% of the subjects screened positive for either an alcohol use disorder and/or for binge drinking using the AUDIT.Male gender and under 65s were risk factors for both alcohol use disorders and binge drinking.Conclusions: The high point-prevalences of alcohol use disorders and binge drinking in hospital inpatients in particular are a cause for concern as they may have illness complicated by or secondary to undiagnosed alcohol excess. As this population is an easily accessible group for screening, and clinical and economic evidence supports intervention, we recommend screening all acute hospital admissions for alcohol use disorders and binge drinking, followed by appropriate management.

Medical Comorbidity Related Risk Factors For Hospital-Based Mortality In Psychiatric Disorders of Icd-10 Classes F1–F4: A Comparative Overview of Five Studies In General Hospital Admissions

2016 ◽  
Vol 33 (S1) ◽  
pp. S485-S485
Author(s):  
D. Schoepf ◽  
R. Heun
Keyword(s):  
Risk Factors ◽  
Psychiatric Disorders ◽  
General Hospital ◽  
Mortality Risk ◽  
Hospital Admissions ◽  
Medical Comorbidity ◽  
Medical Comorbidities ◽  
Related Risk ◽  
Icd 10 ◽  
Independent Risk Factors

IntroductionUp to 60% of the non-suicide related premature mortality of individuals with major psychiatric disorders is said to be mainly due to medical diseases.Objectives and aimsBased on five representative studies in general hospital admissions over 12.5-year observation, we will represent a comparative overview of medical comorbidity related risk factors for general hospital-based mortality in prevalent psychiatric disorders of ICD-10 major classes F1–F4.MethodsIn the original studies, medical comorbidities that increased the risk for hospital-based mortality were identified using multivariate forward logistic regression analysis. In secondary analysis, independent risk factors for general hospital-based mortality were compared between studies using the OR and the 95% CI.ResultsA total of fifteen medical comorbidities represented independent risk factors for general hospital-based mortality in more than one psychiatric disorder of ICD-10 major classes F1–F4. Infectious lung diseases and chronic obstructive pulmonary disease were mortality risk factors in all diagnostic classes. Type 2 diabetes mellitus represented a risk factor for general hospital-based mortality in individuals with schizophrenia (SCH), bipolar disorder (BD), and major depressive disorder (MDD). Atrial fibrillation was a mortality risk factor in individuals with MDD, anxiety disorder (ANX), and alcohol dependence (AD). In addition, nineteen medical comorbidities represented independent mortality risk factors in only one of the diagnostic classes, i.e. two in individuals with SCH, three in individuals with MDD, three in ANX, and eleven in AD.ConclusionsIn general hospitals, the pattern of medical comorbidities that explain the outcome of in-hospital deaths differs considerably between psychiatric disorders of ICD-10 major classes F1–F4.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Risk Factors for Non-communicable Diseases among Adults of 25-65 Years at Kakamega County General Hospital, Kenya

2018 ◽  
Vol 7 (4) ◽  
pp. 274
Author(s):  
Monicah Njambi Kibe ◽  
Gordon Nguka ◽  
Silvenus Konyole
Keyword(s):  
Risk Factors ◽  
Total Cholesterol ◽  
General Hospital ◽  
Hospital Admissions ◽  
Communicable Diseases ◽  
Hospital Data ◽  
Non Communicable Diseases ◽  
Significance Level ◽  
Physical Measurements ◽  
Lipid Parameters

In Kenya the growing number of premature deaths with half of all hospital admissions and 33% of all deaths are associated with Non-communicable diseases. The study determined the physical measurements and lipid parameters of adults 25-65 years at Kakamega County General Hospital. Data was collected using the WHO STEPs Instrument: Physical measurements assessed were Mid Upper Arm Circumference, Waist Hip measurements, Body mass Index and blood pressure. The study significance level was 0.05.  Data was analyzed using SPSS version 20. Descriptive statistics was used. χ<sup>2</sup> test of independence was used to find out the relationship between anthropometric measurements and lipid parameters. Data was presented in form of tables, figures and texts. There was a significant relationship between BMI and Triglycerideχ<sup>2</sup> (12, N=60)= 25.752 P=0.012, BMI and LDLχ<sup>2</sup>(8,N=60)=19.312 p=0.013, BMI and Total Cholesterol χ<sup>2</sup>(8, N=60)=18.694 p=0.017, MUAC and HDL χ<sup>2</sup>(4, N=60) =14.446 p=0.006, WHR and Total Cholesterol χ<sup>2</sup>(2, N=60)=17.985 p=0.000, WHR and LDL χ<sup>2</sup>(2, N=60)=15.246p=0.000. The study advocated for policies to reduce the incidences of risk factors for NCDs which will assist in achievement of Sustainable Development Goals. Kenyan population are in need of screening for risks associated with NCDs.

Alcohol dependence and physical comorbidity: Increased prevalence but reduced relevance of individual comorbidities for hospital-based mortality during a 12.5-year observation period in general hospital admissions in urban North-West England

2015 ◽  
Vol 30 (4) ◽  
pp. 459-468 ◽  
Author(s):  
D. Schoepf ◽  
R. Heun
Keyword(s):  
Logistic Regression ◽  
Alcohol Dependence ◽  
General Hospital ◽  
Hospital Admissions ◽  
Control Sample ◽  
Deficiency Anemia ◽  
Renal Diseases ◽  
Admission Diagnosis ◽  
Chronic Obstructive ◽  
Observation Period

AbstractPurpose:Alcohol dependence (AD) is associated with an increase in physical comorbidities. The effects of these diseases on general hospital-based mortality are unclear. Consequently, we conducted a mortality study in which we investigated if the burden of physical comorbidities and their relevance on general hospital-based mortality differs between individuals with and without AD during a 12.5-year observation period in general hospital admissions.Methods:During 1 January 2000 and 30 June 2012, 23,371 individuals with AD were admitted at least once to seven General Manchester Hospitals. Their physical comorbidities with a prevalence ≥ 1% were compared to those of 233,710 randomly selected hospital controls, group-matched for age and gender (regardless of primary admission diagnosis or specialized treatments). Physical comorbidities that increased the risk of hospital-based mortality (but not outside of the hospital) during the observation period were identified using multiple logistic regression analyses.Results:Hospital-based mortality rates were 20.4% in the AD sample and 8.3% in the control sample. Individuals with AD compared to controls had a higher burden of physical comorbidities, i.e. alcoholic liver and pancreatic diseases, diseases of the conducting airways, neurological and circulatory diseases, diseases of the upper gastrointestinal tract, renal diseases, cellulitis, iron deficiency anemia, fracture neck of femur, and peripheral vascular disease. In contrast, coronary heart related diseases, risk factors of cardiovascular disease, diverticular disease and cataracts were less frequent in individuals with AD than in controls. Thirty-two individual physical comorbidities contributed to the prediction of hospital-based mortality in univariate analyses in the AD sample; alcoholic liver disease (33.7%), hypertension (16.9%), chronic obstructive pulmonary disease (14.1%), and pneumonia (13.3%) were the most frequent diagnoses in deceased individuals with AD. Multiple forward logistic regression analysis, accounting for possible associations of diseases, identified twenty-three physical comorbidities contributing to hospital-based mortality in individuals with AD. However, all these comorbidities had an equal or even lower impact on hospital-based mortality than in the comparison sample.Conclusion:The excess of in-hospital deaths in general hospitals in individuals with AD is due to an increase of multiple physical comorbidities, even though individual diseases have an equal or even reduced impact on general hospital-based mortality in individuals with AD compared to controls.

Hemmkörperentwicklung bei Hämophilie-Patienten nach Präparate wechsel

2012 ◽  
Vol 32 (S 01) ◽  
pp. S39-S42 ◽  
Author(s):  
S. Kocher ◽  
G. Asmelash ◽  
V. Makki ◽  
S. Müller ◽  
S. Krekeler ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Observational Study ◽  
Retrospective Observational Study ◽  
Frequent Change ◽  
Patient Age ◽  
Treatment Regimens ◽  
Patient Âgé ◽  
The Relationship ◽  
Observation Period

SummaryThe retrospective observational study surveys the relationship between development of inhibitors in the treatment of haemophilia patients and risk factors such as changing FVIII products. A total of 119 patients were included in this study, 198 changes of FVIII products were evaluated. Results: During the observation period of 12 months none of the patients developed an inhibitor, which was temporally associated with a change of FVIII products. A frequent change of FVIII products didn’t lead to an increase in inhibitor risk. The change between plasmatic and recombinant preparations could not be confirmed as a risk factor. Furthermore, no correlation between treatment regimens, severity, patient age and comorbidities of the patients could be found.

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