scholarly journals The neurological sequelae of pandemics and epidemics

2020 ◽  
Author(s):  
Fernanda Valerio ◽  
Daniel P. Whitehouse ◽  
David K. Menon ◽  
Virginia F. J. Newcombe
Keyword(s):  
Nervous System ◽  
Neurological Manifestations ◽  
Human History ◽  
Neurological Damage ◽  
Secondary Complications ◽  
Neurological Sequelae ◽  
Physiological Processes ◽  
Short And Long Term ◽  
Long Term Consequences

Abstract Neurological manifestations in pandemics frequently cause short and long-term consequences which are frequently overlooked. Despite advances in the treatment of infectious diseases, nervous system involvement remains a challenge, with limited treatments often available. The under-recognition of neurological manifestations may lead to an increase in the burden of acute disease as well as secondary complications with long-term consequences. Nervous system infection or dysfunction during pandemics is common and its enduring consequences, especially among vulnerable populations, are frequently forgotten. An improved understanding the possible mechanisms of neurological damage during epidemics, and increased recognition of the possible manifestations is fundamental to bring insights when dealing with future outbreaks. To reverse this gap in knowledge, we reviewed all the pandemics, large and important epidemics of human history in which neurological manifestations are evident, and described the possible physiological processes that leads to the adverse sequelae caused or triggered by those pathogens.

scholarly journals The Other Side of SARS-CoV-2 Infection: Neurological Sequelae in Patients

2021 ◽  
Vol 13 ◽  
Author(s):  
Isabel M. Alonso-Bellido ◽  
Sara Bachiller ◽  
Guillermo Vázquez ◽  
Luis Cruz-Hernández ◽  
Emilio Martínez ◽  
...  
Keyword(s):  
Nervous System ◽  
Distress Syndrome ◽  
Immune Reaction ◽  
Cerebrovascular Disorders ◽  
Neurological Complications ◽  
Review Article ◽  
Neurological Sequelae ◽  
Long Term Consequences ◽  
Taste And Smell

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread around the globe causing coronavirus disease 2019 (COVID-19). Because it affects the respiratory system, common symptoms are cough and breathing difficulties with fever and fatigue. Also, some cases progress to acute respiratory distress syndrome (ARDS). The acute phase of COVID-19 has been also related to nervous system symptoms, including loss of taste and smell as well as encephalitis and cerebrovascular disorders. However, it remains unclear if neurological complications are due to the direct viral infection of the nervous system, or they appear as a consequence of the immune reaction against the virus in patients who presented pre-existing deficits or had a certain detrimental immune response. Importantly, the medium and long-term consequences of the infection by SARS-CoV-2 in the nervous system remain at present unknown. This review article aims to give an overview of the current neurological symptoms associated with COVID-19, as well as attempting to provide an insight beyond the acute affectation.

scholarly journals Neurological involvement of COVID-19: from neuroinvasion and neuroimmune crosstalk to long-term consequences

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Dian Eurike Septyaningtrias ◽  
Rina Susilowati
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Immune Responses ◽  
Nerve Degeneration ◽  
Neurological Involvement ◽  
Neurological Manifestations ◽  
The Central Nervous System ◽  
Coronavirus Infection ◽  
Long Term Consequences

Abstract As the coronavirus disease 2019 (COVID-19) pandemic continues to be a multidimensional threat to humanity, more evidence of neurological involvement associated with it has emerged. Neuroimmune interaction may prove to be important not only in the pathogenesis of neurological manifestations but also to prevent systemic hyperinflammation. In this review, we summarize reports of COVID-19 cases with neurological involvement, followed by discussion of possible routes of entry, immune responses against coronavirus infection in the central nervous system and mechanisms of nerve degeneration due to viral infection and immune responses. Possible mechanisms for neuroprotection and virus-associated neurological consequences are also discussed.

THE POWER OF TESTS: A CRITICAL PERSPECTIVE ON THE USES OF LANGUAGE TESTS.Elana Shohamy. London: Longman, 2001. Pp. xxvi + 182. £18.99 paper.

2002 ◽  
Vol 24 (4) ◽  
pp. 644-645 ◽  
Author(s):  
April Ginther
Keyword(s):  
School Administrators ◽  
Educational Institutions ◽  
Motivating Factors ◽  
Critical Perspective ◽  
Policy Makers ◽  
Power Of Tests ◽  
Language Tests ◽  
Short And Long Term ◽  
Long Term Consequences

In the introduction to The power of tests: A critical perspective on the uses of language tests, Elana Shohamy raises the following questions: What is the meaning of a test for test takers, parents, teachers, and school administrators? What are the short- and long-term consequences of tests on the lives of individuals? What are the motivating factors behind the administration of language tests? What are the politics of the tests? These kinds of questions logically arise when the examination of testing includes a concern with the use of tests by educational institutions, policy makers, and society at large. Focusing primarily on the misuse of tests, this volume chronicles both intended and unintended test consequences.

Tracking Emotions over Time (the “ARC”)

2021 ◽  
pp. 81-92
Author(s):  
Heather Thompson-Brenner ◽  
Melanie Smith ◽  
Gayle Brooks ◽  
Dee Ross Franklin ◽  
Hallie Espel-Huynh ◽  
...  
Keyword(s):  
Emotional Responses ◽  
Emotional Experiences ◽  
Short And Long Term ◽  
Long Term Consequences ◽  
And Behaviors ◽  
Over Time

The primary goal for this session is for clients to explore and learn how emotional experiences unfold. This allows clients to learn from their emotional experiences and how these experiences can influence their later behaviors and emotions. During this session, clients learn the steps that unfold over time in emotions: antecedent (A, what happened before), response (R, which includes thoughts, physical sensations, and behaviors/urges), and consequence (C, what happens after). Clients learn to look for patterns in their emotional triggers. They also learn to explore short- and long-term consequences of their emotional responses. Form 8.1: The ARC of Emotional Experiences is introduced.

scholarly journals West Nile Virus Infection in the Central Nervous System

F1000Research ◽  
2016 ◽  
Vol 5 ◽  
pp. 105 ◽  
Author(s):  
Evandro R. Winkelmann ◽  
Huanle Luo ◽  
Tian Wang
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
West Nile Virus ◽  
Animal Models ◽  
West Nile Virus Infection ◽  
The United States ◽  
West Nile ◽  
Neurological Sequelae ◽  
The Central Nervous System

West Nile virus (WNV), a neurotropic single-stranded flavivirus has been the leading cause of arboviral encephalitis worldwide.  Up to 50% of WNV convalescent patients in the United States were reported to have long-term neurological sequelae.  Neither antiviral drugs nor vaccines are available for humans.  Animal models have been used to investigate WNV pathogenesis and host immune response in humans.  In this review, we will discuss recent findings from studies in animal models of WNV infection, and provide new insights on WNV pathogenesis and WNV-induced host immunity in the central nervous system.

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