Intensified postoperative care versus conventional follow-up: a retrospective long-term analysis of 177 trabeculectomies

2003 ◽  
Vol 242 (2) ◽  
pp. 106-113 ◽  
Author(s):  
Dirk Marquardt ◽  
Wolfgang E. Lieb ◽  
Franz Grehn
Keyword(s):  
Postoperative Care ◽  
Term Analysis

Long-Term Analysis of the IFM 99 Trials for Myeloma: Cytogenetic Abnormalities [t(4;14), del(17p), 1q gains] Play a Major Role in Defining Long-Term Survival

2012 ◽  
Vol 30 (16) ◽  
pp. 1949-1952 ◽  
Author(s):  
Hervé Avet-Loiseau ◽  
Michel Attal ◽  
Loic Campion ◽  
Denis Caillot ◽  
Cyrille Hulin ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Life Expectancy ◽  
Comprehensive Analysis ◽  
Newly Diagnosed ◽  
Term Survival ◽  
Risk Patients ◽  
Chromosomal Changes ◽  
Term Analysis

Purpose In multiple myeloma, many prognostic parameters have been proposed. However, all of these predict shorter survival. To identify patients with a longer life expectancy, we updated the data of patients treated in the IFM (Intergroupe Francophone du Myelome) 99-02 and 99-04 trials. Patients and Methods A series of 520 patients was analyzed. Median follow-up was 90.5 months. To perform a comprehensive analysis of the major prognostic factors, we reanalyzed all patients for 1q gains [in addition to updating del(13), t(4;14), and del(17p) analyses]. Results It was possible to identify a subgroup of patients (representing 20% of total patients) with an 8-year survival of 75%. These patients were defined by the absence of t(4;14), del(17p), and 1q gain and β2-microglobulin less than 5.5 mg/L. Conclusion We propose that all patients with newly diagnosed multiple myeloma be evaluated for these three chromosomal changes, not only to define high-risk patients but also to identify those with a longer life expectancy.

scholarly journals Patient Loss to Follow-up After Upper Extremity Surgery: A Review of 2563 Cases

Hand ◽  
2018 ◽  
Vol 14 (6) ◽  
pp. 836-840
Author(s):  
Joseph A. Rosenbaum ◽  
Yoni M. Blau ◽  
Hannah K. Fox ◽  
X. Shawn Liu ◽  
Alex C. DiBartola ◽  
...  
Keyword(s):  
Upper Extremity ◽  
Postoperative Care ◽  
Private Insurance ◽  
Demographic Variables ◽  
Loss To Follow Up ◽  
Long Term Follow Up ◽  
Lost To Follow Up ◽  
Surgery Center

Background: Postoperative care is essential to optimizing patient outcome. We sought to determine the incidence and associated demographic and surgical factors of postoperative patient loss to follow-up following hand and upper extremity surgery. Methods: In all, 2834 surgical cases (2467 patients) were retrospectively reviewed. All surgical cases from July 2014 to June 2015 at a single practice with five surgeons were assessed. Charts were reviewed for compliance with postoperative follow-up. Variables were described with proportions and compared using logistic regression analysis. Results: In total, 2563 cases (2388 patients) met the inclusion criteria. Overall loss to follow-up rate was 26%. Patients lost to follow-up based on insurance type were 13% for worker’s compensation, 22% for private insurance, 21% for Medicare, 38% for Medicaid, and 44% for self-pay. Patients with expected short-term follow-up were lost at a 23% rate. Expected mid- and long-term follow-up patients were lost at 34% and 20% rates, respectively. Patients below 30 years old were lost to follow-up at a 42% rate compared to patients 30 to 64 years old (26%) and greater than or equal to 65 years (13%). Males had a higher rate of loss to follow-up, 32%, compared with females (22%). Patients living greater than 50 miles from our surgery center were lost to follow-up at a rate of 31%, compared with those who lived less than 50 miles (25%). Conclusions: We have identified demographic variables associated with patients being lost to follow-up after hand and upper extremity surgery. With this knowledge, we hope to develop methods of either improving in-office follow-up rates or discover new avenues to deliver postoperative care.

scholarly journals Continued Risk of Relapse Independent of Treatment Modality in Limited-Stage Diffuse Large B-Cell Lymphoma: Final and Long-Term Analysis of Southwest Oncology Group Study S8736

2016 ◽  
Vol 34 (25) ◽  
pp. 2997-3004 ◽  
Author(s):  
Deborah M. Stephens ◽  
Hongli Li ◽  
Michael L. LeBlanc ◽  
Soham D. Puvvada ◽  
Daniel Persky ◽  
...  
Keyword(s):  
Cell Lymphoma ◽  
Combined Modality Therapy ◽  
B Cell Lymphoma ◽  
Southwest Oncology Group ◽  
Limited Stage ◽  
Large B Cell Lymphoma ◽  
Term Analysis ◽  
Large B Cell

Purpose Utility of combined-modality therapy for patients with limited-stage diffuse large B-cell lymphoma (DLBCL) was shown in the Southwest Oncology Group (SWOG) S8736 study, where three cycles of CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone) plus radiotherapy (CHOP3RT) improved 5-year progression-free (PFS) and overall survival (OS) compared with eight cycles of CHOP (CHOP8). Subsequent analysis showed an unexpected overlap of the PFS curves. We aimed to confirm and investigate this observation by performing long-term analysis of SWOG S8736 and evaluating these data alongside data from similar patients receiving rituximab and CHOP3RT (SWOG S0014 study). Patients and Methods A subset of patients with limited-stage DLBCL randomly assigned to CHOP8 (n = 150) or CHOP3RT (n = 158) in S8736 was analyzed along with a 56-patient subset treated in S0014 for long-term PFS and OS. Results Median follow-up in S8736 was 17.7 years. In patients receiving CHOP8 and CHOP3RT, median PFS was 12.0 (95% CI, 8.8 to 14.3) and 11.1 years (95% CI, 8.9 to 14.4), respectively. There were no statistically significant differences in PFS between the groups (P = .73). Median OS was 13.0 (95% CI, 10.4 to 15.2) and 13.7 years (95% CI, 11.1 to 19.4) for patients treated with CHOP8 and CHOP3RT, respectively. Similarly, there were no statistically significant differences in OS between the groups (P = .38). With a median follow-up time 12 years in S0014, 5- and 10-year OS were 82% and 67%, respectively, with a persistent pattern of relapse despite the addition of rituximab. Conclusion Although 5-year PFS and OS were improved after early analysis in patients with limited-stage DLBCL receiving CHOP3RT versus CHOP8, extended survival data showed similar PFS and OS, with continuous treatment failure. The addition of rituximab (S0014) to combined-modality therapy did not mitigate the continued relapse risk, underscoring the value of prolonged clinical trial patient observation and possible unique biology of limited-stage DLBCL.

scholarly journals Hunting practices among the Awá-Guajá: towards a long-term analysis of sustainability in an Amazonian indigenous community

2012 ◽  
Vol 7 (2) ◽  
pp. 479-491 ◽  
Author(s):  
Helbert Medeiros Prado ◽  
Louis Carlos Forline ◽  
Renato Kipnis
Keyword(s):  
Forest Cover ◽  
Clear Correlation ◽  
Foraging Patterns ◽  
Ethnographic Fieldwork ◽  
Acquisition Strategies ◽  
Diachronic Analysis ◽  
Term Analysis ◽  
Indigenous Reserves

Indigenous Reserves have played an indispensable role in maintaining forest areas in the Neotropics. In the Amazon there is a clear correlation between these reserves and the presence of forest cover; however, the simple presence of uninterrupted vegetation is no guarantee for the conservation of biodiversity, especially where hunting is practiced. This study describes hunting practices among the Awá-Guajá people from 1993 through 1994, also identifying sociocultural, technological, and demographic changes that have influenced their resource acquisition strategies over the last two decades. The data was obtained through ethnographic fieldwork, recording 78 days of foraging returns, with follow-up visits through 2010. This work provides useful information for an effective diachronic analysis of hunting in this community, by revealing foraging patterns of the early to mid-1990s, and describing community transformations over the last two decades in this locale.

Long Term Follow-up Analysis of HD9601 Trial Comparing ABVD Vs Stanford V Vs MOPPABVCAD in Patients with Newly Diagnosed Advanced Stage Hodgkin Lymphoma. A Study from the Intergruppo Italiano Linfomi (IIL)

Blood ◽  
2008 ◽  
Vol 112 (11) ◽  
pp. 2602-2602 ◽  
Author(s):  
Teodoro Chisesi ◽  
Monica Bellei ◽  
Stefano Luminari ◽  
Luigi Marcheselli ◽  
Alessandro Levis ◽  
...  
Keyword(s):  
Hodgkin Lymphoma ◽  
Initial Treatment ◽  
Survival Rates ◽  
Advanced Stage ◽  
End Of Treatment ◽  
Long Term Follow Up ◽  
Involved Field ◽  
Term Analysis

Abstract PURPOSE: To provide long term follow-up results of HD9601 trial that compared ABVD vs MOPP-EBV-CAD (MEC) vs Stanford V (StV) regimens for the initial treatment of patients with advanced stage Hodgkin Lymphoma (HL) PATIENTS AND Methods: Patients with stage IIB–III or IV were eligible for randomization among 6 cycles of ABVD, 6 cycles of MEC and 12 weeks of StV; treatment had to be consolidated with optional Involved Field radiotherapy on Bulky or slow responding sites. For the long term, follow-up analysis study database was updated with most recent follow-up data and with information on long-term toxicity. Results: Between 1996 and 2000, 355 patients were registered into the trial and were randomly assigned to one of the three arms (ABVD 122 pts, MEC 106 pts, and StV 107 pts). Radiotherapy was administered to 62%, 47%, and 66% of cases in the 3 arms respectively. As previously described response rates at the end of treatment program were 89%, 94%, and 76% in the 3 arms, respectively. Initial results were published in 2005 with a median f-up of 61 months. Median follow-up of current analysis is 86 months. Compared with previous data we observed 2 additional relapses, both in StV arm. Moreover, we observed 7 additional deaths in patients who had achieved a CR after initial treatment. Overall, 20 patients died after achievement of CR with 7 additional events compared with our previous report (Gobbi et al. JCO 2007). Overall analyzing data by study arm we observed 4 (+3), 11 (+3), and 5 (+1) deaths in CR patients randomized toABVD, MEC, and StV, respectively. Additional deaths in CR from previous report were further analyzed and were caused by pulmonary embolism (3 cases: 2 ABVD, 1 MEC), sepsis (2 cases: 1 MEC, 1 StV), LMA (1 MEC), and second cancer NOS (1 ABVD). No additional significant longterm toxic event was recorded. Long-term analysis resulted in 8-yr OS of 88%, 84%, and 77% for ABVD, MEC, and StV, respectively without differences among study arms (P=0.337). Conclusions: The long-term analysis of HD9601 trial confirmed the results of the initial analysis. Few additional events observed were mostly represented by deaths in CR patients but these events did not substantially modify survival rates of the three arms.

scholarly journals Long-Term Analysis of Respiratory-Related Complications Following Gastrostomy Placement with or without Fundoplication in Neurologically Impaired Children: A Retrospective Cohort Study

Children ◽  
2021 ◽  
Vol 8 (1) ◽  
pp. 22
Author(s):  
Elisa Zambaiti ◽  
Calogero Virgone ◽  
Silvia Bisoffi ◽  
Roberta Stefanizzi ◽  
Francesco Fascetti Leon ◽  
...  
Keyword(s):  
Hospital Admissions ◽  
Respiratory Complications ◽  
Long Term Outcomes ◽  
Neurologically Impaired ◽  
Respiratory Problems ◽  
Adequate Food ◽  
Impaired Children ◽  
Term Analysis

Gastrostomy placement is crucial in neurologically impaired (NI) children to ensure an adequate food intake and a safe route for drugs administration and to reduce the risk of primary aspiration. NI patents are more prone to gastroesophageal reflux. The association with fundoplication is deemed to reduce reflux-related respiratory complications. However, long-term benefits of this approach are not clear. We therefore aimed to compare long-term reflux-related respiratory complications of gastrostomy only (GO) to gastrostomy with fundoplication (GF). We retrospectively reviewed 145 consecutive NI children managed from 2008 to 2018. As long-term outcomes, we analyzed number and length of hospital admissions (Reflux-Related-Hospitalization, RRH) and emergency department accesses (Reflux-Related-Accesses, RRA) due to respiratory problems. Results were analyzed with appropriate statistical method. Median age at referral and at gastrostomy placement were 2.2 and 3.4 years (SD 5.6), respectively. Median follow-up was four years (range 1–12). Anti-reflux procedures were performed in 26/145 patients (18%); tracheotomy in 23/145 (16%). RRH following surgery showed lower number of admissions/year (0.32 vs. 1 for GO vs. GF, p < 0.005) and days hospitalization/year (3 vs. 13, p = 0.08) in GO compared to GF; RRA was similar (0.60 vs. 0.65, p = 0.43). Gastrostomy placement alone appeared not to be inferior to gastrostomy plus fundoplication with respect to long-term respiratory-related outcomes for NI children in our center.

Incus Interposition

1983 ◽  
Vol 92 (6) ◽  
pp. 568-570 ◽  
Author(s):  
Claude L. Pennington
Keyword(s):  
Middle Ear ◽  
Postoperative Care ◽  
Follow Up Study

A 10- to 15-year follow-up study of patients with modeled incus interposition procedure for restoration of hearing reveals that hearing gains as reported in 1972 were sustained by long-term postoperative care despite resurgence of problems from negative middle ear air pressures.

scholarly journals Postoperative care and long-term follow-up after a rostral mandibulectomy to treat an ossifying fibroma in a horse

2017 ◽  
Vol 47 (11) ◽  
Author(s):  
Antônio Carlos Lopes Câmara ◽  
Marcel Batista dos Passos ◽  
Anna Beatriz Veltri Peneiras ◽  
Júlio Rafael de Melo Pereira ◽  
Antonio Raphael Teixeira Neto ◽  
...  
Keyword(s):  
Postoperative Care ◽  
Present Report ◽  
Ossifying Fibroma ◽  
Bone Deformity ◽  
Radiographic Findings ◽  
Slow Adaptation ◽  
Long Term Follow Up ◽  
Surgical Recovery

ABSTRACT: Ossifying fibroma is a disfiguring benign neoplasia of the jaw that affects young animals of several species, including horses. The present report described the postoperative care and long-term follow-up after a rostral mandibulectomy (RM) that was performed to treat an ossifying fibroma in a horse. A 3-year-old crossbred horse presented a hard, well-defined, 14.5×10.0×9.5cm ulcerated mass attached to the rostral mandible. Radiographic findings were compatible with a nonaggressive mandibular bone deformity (benign neoplasia). Histological features confirmed the diagnosis of the ossifying fibroma. After the RM, the horse slowly adapted to the new feeding conditions and was discharged when it fully recovered and was capable of feeding on the paddock and drinking water on its own on day 60. This slow adaptation was crucial for post-surgical recovery and required hard labor to manage the feeding and hydration by nasogastric tube during the hospital stay.

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