scholarly journals The first genotype determination of Acanthamoeba potential threat to human health, isolated from natural water reservoirs in Poland

2014 ◽  
Vol 113 (7) ◽  
pp. 2693-2699 ◽  
Author(s):  
Anna Lass ◽  
Beata Szostakowska ◽  
Alicja Idzińska ◽  
Lidia Chomicz

Широкое распространение безнадзорных животных на территории городов несет за собой потенциальную угрозу распространения зооантропонозных заболеваний, одним из которых является демодекоз. Невозможно разработать мероприятия, направленные на борьбу с заболеванием и его профилактику, без анализа данных особенностей возникновения и распространения инвазии среди всей популяции восприимчивых животных. Поэтому целью нашей работы явилось изучение распространения демодекоза среди безнадзорных собак и кошек в городе Тюмени. В задачи исследования входило изучение распространения демодекоза и его клинического проявления среди бездомных собак и кошек в условиях города Тюмени и определение сезонной динамики заболевания. Работу выполняли в 2016-2018 гг. на базе кафедры анатомии и физиологии ФГБОУ ВО ГАУ Северного Зауралья, в лаборатории акарологии ВНИИВЭА – филиала ТюмНЦ СО РАН, а также в производственных условиях на базе пункта временного содержания безнадзорных домашних животных МКУ «ЛесПаркХоз». Демодекозная инвазия распространена среди бездомных кошек и собак. Наиболее часто демодекоз встречается у собак, экстенсивность инвазии от 0,65 до 0,72%. Заболевание демодекозом у бездомных собак регистрировали на протяжении всего года, но 54,6% больных собак поступали в апреле и мае. Большинство больных демодекозом – это молодые собаки в возрасте от 1,5 месяцев до 2-х лет – 75,76%, животные старше двух лет гораздо реже страдали от демодекоза – 24,24%. Генерализацию демодекоза регистрировали у 21 собаки (63,64%), а локализованные очаги – у 12 собак (36,36%). Наиболее распространенной формой проявления демодекоза у бездомных собак является пустулезная, или пиодемодекоз. Данная форма заболевания была отмечена у 16 собак (48,49%), чешуйчатая форма отмечалась у 10 собак (30,30%), а смешанная – у 7 собак (21,21%). The widespread use of stray animals in urban areas carries with it the potential threat of the spread of zooanthroponotic diseases, one of which is demodicosis. It is impossible to develop measures aimed at combating the disease and its prevention without analyzing the data on the characteristics of the occurrence and spread of invasion among the entire population of susceptible animals. Therefore, the purpose of our work was to study the distribution of demodicosis among street dogs and cats in the city of Tyumen. The objectives of the study included the study of the spread of demodicosis and its clinical manifestation among stray dogs and cats in the conditions of the city of Tyumen and the determination of the seasonal dynamics of the disease. Demodectic invasion is common among stray cats and dogs. Most often, demodicosis occurs in dogs, with extensive invasion from 0.65 to 0.72%. Demodecosis in stray dogs was recorded throughout the year, but 54.6% of sick dogs were reported in April and May. The majority of patients with demodicosis are young dogs between the ages of 1.5 months and 2 years old - 75.76%, animals older than two years suffer less from demodicosis, only 24.24%. Generalization of demodicosis was recorded in 21 dogs (63.64%), and localized foci in 12 dogs (36.36%). The most common form of demodicosis in stray dogs is pustular or pyodemodecosis. This form of the disease was observed in 16 dogs (48.49%), scaly form, was observed in 10 dogs (30.30%), and mixed in 7 dogs (21.21%).


2020 ◽  
Vol 16 ◽  
Author(s):  
Ramazan Akçan ◽  
Halit Canberk Aydogan ◽  
Mahmut Şerif Yıldırım ◽  
Burak Taştekin ◽  
Necdet Sağlam

Background/aim: Use of nanomaterials in the healthcare applications increases in parallel to technological developments. It is frequently utilized in diagnostic procedures, medications and in therapeutic implementations. Nanomaterials take place among key components of medical implants, which might be responsible for certain toxic effects on human health at nano-level. In this review, nanotoxicological effects, toxicity determination of nanobiomaterials used in human body and their effects on human health are discussed. Material and Method: A detailed review of related literature was performed and evaluated as per nanomaterials and medical implants. Results and Conclusion: The nanotoxic effects of the materials applied to human body and the determination of its toxicity are important. Determination of toxicity for each nanomaterial requires a detailed and multifactorial assessment considering the properties of these materials. There are limited studies in the literature regarding the toxic effects of nanomaterials used in medical implants. Although these implants are potentially biocompatible and biodegradable, it is highly important to discuss nanotoxicological characteristics of medical implant.


Author(s):  
Ewelina Farian ◽  
Angelina Wójcik-Fatla

AbstractFungi are one of the most widely distributed microorganisms in the environment, including food such as fruits, vegetables and other crops, posing a potential threat to food safety and human health. The aim of this study was to determine the diversity, intensity and drug resistance of potentially pathogenic filamentous fungi isolated from the fresh raspberries (Rubus idaeus L.). A total of 50 strains belonging to genera Fusarium, Cladosporium, Alternaria, Penicillium, Mucor, Rhizopus, Aspergillus and Acremonium were tested for drug resistance against 11 antifungals by disc diffusion and gradient strips methods. The average mycological contamination in the examined samples of raspberries amounted to 4.34 log CFU/g. The Cladosporium was isolated from all tested samples, followed by Alternaria and Fusarium with a frequency of 61% and 34%, respectively. The highest level of drug resistance was observed for Acremonium genera and Fusarium strains recorded a wide variation in drug resistance as revealed by susceptibility with amphotericin B and voriconzole with MICs ranged from 0.5–4 µg/ml and posaconazole with MICs ranging from 3–8 µg/ml. All fungal strains showed 100% resistance to caspofungin, fluconazole and flucytosine with both the methods, and 100% resistance to micafungin and anidulafungin in the gradient strip method.


Plants ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 639
Author(s):  
Alexandre Campos ◽  
El Mahdi Redouane ◽  
Marisa Freitas ◽  
Samuel Amaral ◽  
Tomé Azevedo ◽  
...  

Cyanobacteria are a group of photosynthetic prokaryotes that pose a great concern in the aquatic environments related to contamination and poisoning of wild life and humans. Some species of cyanobacteria produce potent toxins such as microcystins (MCs), which are extremely aggressive to several organisms, including animals and humans. In order to protect human health and prevent human exposure to this type of organisms and toxins, regulatory limits for MCs in drinking water have been established in most countries. In this regard, the World Health Organization (WHO) proposed 1 µg MCs /L as the highest acceptable concentration in drinking water. However, regulatory limits were not defined in waters used in other applications/activities, constituting a potential threat to the environment and to human health. Indeed, water contaminated with MCs or other cyanotoxins is recurrently used in agriculture and for crop and food production. Several deleterious effects of MCs including a decrease in growth, tissue necrosis, inhibition of photosynthesis and metabolic changes have been reported in plants leading to the impairment of crop productivity and economic loss. Studies have also revealed significant accumulation of MCs in edible tissues and plant organs, which raise concerns related to food safety. This work aims to systematize and analyze the information generated by previous scientific studies, namely on the phytotoxicity and the impact of MCs especially on growth, photosynthesis and productivity of agricultural plants. Morphological and physiological parameters of agronomic interest are overviewed in detail in this work, with the aim to evaluate the putative impact of MCs under field conditions. Finally, concentration-dependent effects are highlighted, as these can assist in future guidelines for irrigation waters and establish regulatory limits for MCs.


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