Anterior management of C2 fractures using miniplate fixation: outcome, function and quality of life in a case series of 15 patients

2018 ◽  
Vol 27 (6) ◽  
pp. 1332-1341 ◽  
Author(s):  
Axel Franke ◽  
Dan Bieler ◽  
Rebecca Wern ◽  
Tim Trotzke ◽  
Sebastian Hentsch ◽  
...  
2008 ◽  
Vol 36 (2) ◽  
pp. 369-374 ◽  
Author(s):  
Panagiotis Baltopoulos ◽  
Charalampos Tsintzos ◽  
George Prionas ◽  
Maria Tsironi

Background Thoracic outlet syndrome is described as a group of distinct disorders producing signs and symptoms attributed to compression of nerves and blood vessels in the thoracic outlet region. Purpose To describe the exercise-induced scalenus anticus syndrome attributed to the anterior scalenus hypertrophy as a thoracic outlet syndrome underlying mechanism and to give recommendations for a safe and effective surgical treatment. Study Design Case series; Level of evidence, 4. Methods Twelve young professional athletes admitted for thoracic outlet syndrome (8 cases of neurologic thoracic outlet syndrome, 4 cases of mixed neurologic and vascular thoracic outlet syndrome) who reported numbness, tingling, early fatigue, muscle weakness, and pain were enrolled in the study. Scalenus hypertrophy was suspected to be the causative factor. Scalenectomy was performed in all cases. Results All patients had moderate to severe hypertrophy of the anterior scalenus muscle. Scalenectomy was performed, and there were no intraoperative or postoperative complications. Full activity was quickly achieved, and no recurrence of symptoms was documented. Conclusion Surgical intervention for scalenus anticus syndrome can allow an athlete to return to full activity and improve quality of life. Surgical intervention seems to be the treatment of choice in terms of restoring quality of life and physical activity.


2021 ◽  
Vol 104 (4) ◽  
pp. 672-675

The present case series described six chronic immune thrombocytopenia patients (cITP), with a median age of 7.7 (7.0 to 13.0) years and low platelet count at 15,500 (7,000 to 20,000)/uL. They were suffering from bleeding symptoms and side effects of treatment. After enrollment, they were treated with thrombopoietin receptor agonist (eltrombopag). Five patients responded positively, showing a median platelet count of 115,000 (39,000 to 433,000)/uL. The median dose of eltrombopag used was 1.3 (0.8 to 2.2) mg/kg/day. The quality of life (QoL) improved for all patients, with their median overall score using a Pediatric QoL questionnaire showing 25.0% improvement. Median scores also showed improvements in each sphere of life functioning as physical (30.8%), emotional (26.4%), social (16.4%), and school (21.4%). The present report demonstrated that a select group of cITP patients, with low platelet count and bleeding symptoms, benefitted from treatment with eltrombopag, as shown by increased platelet counts and improved QoL. Keywords: Chronic ITP, Thrombopoietin receptor agonist, Children


2009 ◽  
Vol 67 (3b) ◽  
pp. 812-817 ◽  
Author(s):  
Leandro Alberto Calazans Nogueira ◽  
Felipe Resende Nóbrega ◽  
Kátia Nogueira Lopes ◽  
Luiz Claudio Santos Thuler ◽  
Regina Maria Papais Alvarenga

The purpose of this study was to determine the effect of functional limitations and fatigue on the quality of life (QoL) in people with multiple sclerosis (MS). A descriptive case series study at Lagoa Hospital - Rio de Janeiro, Brazil was carried. The main outcome measurements were demographic variables, QoL (SF-36 v.1), disability (EDSS), motor function of the upper limb (Box & Blocks test), Tone (Modified Ashworth Scale), gait (Hauser ambulatory index) and fatigue (Fatigue Severity Scale). Sixty one patients fulfilled the study criteria. The mean age of patients was 39 years and 74% of patients were female. The most of cases presented mild disability (EDSS<3.5). A decrease was found in all domains of QoL. It was found association between physical functioning and the variables of EDSS, fatigue, lower limb tone and gait. Gait, disability, hypertonia of the lower limbs and fatigue negatively affected QoL in people with MS.


2015 ◽  
Vol 150 (4) ◽  
pp. 947-954 ◽  
Author(s):  
Amedeo Anselmi ◽  
Erwan Flécher ◽  
Hervé Corbineau ◽  
Thierry Langanay ◽  
Vincent Le Bouquin ◽  
...  

2014 ◽  
Vol 27 (4) ◽  
pp. 505-514 ◽  
Author(s):  
Karina Maria Cancelliero-Gaiad ◽  
Daniela Ike ◽  
Liliana Soave ◽  
Evelim Leal de Freitas Dantas Gomes ◽  
Fernanda Dultra Dias ◽  
...  

Objective To correlate functional capacity test scores from chronic obstructive pulmonary disease (COPD) subjects with their functional state as assessed by health-related quality of life questionnaires (one respiratory disease-specific [SGRQ] and one generic [SF-36] questionnaire). Materials and methods Study of a case series of 8 COPD patients. The following tests were performed: 1) Six-minute walk test (6-MWT); 2) Shuttle walking test (SWT); 3) Six-minute step test (6-MST); 4) Two-minute sit-to-stand test (STST); and 5) Pegboard and ring test (PBRT). Besides these tests, two health-related quality of life questionnaires were administered: The St George's Respiratory Questionnaire (SGRQ) and the Short Form 36 (SF-36) health survey questionnaire. The statistical analysis was carried out by using the Shapiro-Wilk normality test, while correlations were assessed using Pearson's (parametric data) or Spearman's (non-parametric data) rank tests, with p < 0.05. Results The 6-MWT showed strong correlation with the SF-36 scales of physical functioning, general health, vitality, social functioning and mental health. Conversely, the other functional capacity tests showed no correlation with this questionnaire. The SGRQ showed no correlation with any of the tests. Conclusions The 6-MWT may be a good test to reflect the health-related quality of life of COPD subjects.


EXPLORE ◽  
2012 ◽  
Vol 8 (2) ◽  
pp. 127-135 ◽  
Author(s):  
Mary Lou Galantino ◽  
Laurie Greene ◽  
Laura Daniels ◽  
Brandon Dooley ◽  
Laura Muscatello ◽  
...  

2011 ◽  
Vol 9 (1) ◽  
pp. 65 ◽  
Author(s):  
Elen B Pinto ◽  
Iara Maso ◽  
Julio LB Pereira ◽  
Thiago G Fukuda ◽  
Jamile C Seixas ◽  
...  

Author(s):  
Joel H Fuhrman ◽  
Deana M Ferreri

Adherence to healthy lifestyle behaviors in cancer survivors has the potential to reduce the risk of recurrence and improve quality of life. Although whole diet intervention studies in cancer survivors are scarce, the available evidence supports a plant-based diet, and the World Cancer Research Fund (WCRF) recommends following cancer prevention diet and lifestyle guidelines to reduce the risk of recurrence. There is sufficient evidence to presume that the same phytochemical-rich foods that have been shown to reduce the risk of developing cancer (prevention) are beneficial and lifespan promoting for those who have a diagnosis of cancer. The nutrient-dense, plant-rich (NDPR) diet (also called a Nutritarian diet) is a plant-based diet that places emphasis on foods with evidence backing anti-tumor activity such as inhibition of proliferation and angiogenesis, apoptosis promotion, anti-inflammatory effects, and induction of the master regulator of detoxification and antioxidant response nuclear factor erythroid 2-related factor 2 (Nrf2): leafy green vegetables, beans, garlic and onion, seeds and nuts, mushrooms, berries, and other carotenoid-rich fruits and vegetables, assuring rich sources of phytonutrients and plant lignans. Here, we present seven cases of patients who had adopted the NDPR diet following a cancer diagnosis and conveyed details of their results. Patients generally reported improved quality of life, intentional weight loss, no recurrence, and improvement in other aspects of health in the years after cancer diagnosis provoked their dietary change.


2020 ◽  
Vol 163 (2) ◽  
pp. 356-363
Author(s):  
Chen Lin ◽  
Stephen Y. Kang ◽  
Samantha Donermeyer ◽  
Theodoros N. Teknos ◽  
Sharla M. Wells-Di Gregorio

Objective Patients with head and neck cancer (HNC) face a unique set of unmet needs. A subset of these patients experience symptom control challenges related to their disease burden and treatments. A multidisciplinary approach involving palliative medicine is underutilized but crucial to identify and address these concerns. There is limited information on palliative integration with head and neck oncology. Study Design Case series with planned data collection. Setting Academic quaternary care center. Subjects and Methods We provide descriptive analyses of patients with HNC, including psychodiagnostic assessment and validated quality-of-life screening, from patients’ first encounter at outpatient palliative medicine. Results HNC (N = 80) contributed the greatest number of palliative referrals (25%) between 2010 and 2012. This cohort was 74% male and 79% Caucasian with a mean age of 53 years (95% CI, 51.1-54.9) and with stage IV disease of the oral cavity (28%) or oropharynx (31%). Sixty-three percent of patients had no evidence of disease. Seventy-five percent had a psychological history based on DSM-IV criteria ( Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition), and 70% had a history of substance use disorder. The most distressing quality-of-life concerns were pain, housing and financial problems, and xerostomia. Conclusions Patients with HNC who were referred to palliative medicine are burdened by multiple physical, psychological, substance use, and social challenges. We recommend comprehensive cancer-specific screening, such as the James Supportive Care Screening, to triage patients to appropriate supportive care services. Palliative care is one of many services that these patients may need, and it should be utilized at any point of the disease trajectory rather than reserved for end-of-life care.


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