Cross-sectional study discloses a positive family history for Parkinson’s disease and male gender as epidemiological risk factors for substantia nigra hyperechogenicity

2007 ◽  
Vol 114 (9) ◽  
pp. 1167-1171 ◽  
Author(s):  
K. J. Schweitzer ◽  
S. Behnke ◽  
I. Liepelt ◽  
B. Wolf ◽  
C. Grosser ◽  
...  
Author(s):  
Vijayakarthikeyan M. ◽  
Dhanuraja V.

Background: Cardio vascular disease (CVD) is the number 1 cause of death globally and an estimated 17.7 million people died from CVD in 2015, representing 31% of all global deaths. In India CVD accounts for 25% of all deaths. The objectives of the study was to estimate the prevalence of CVD among the study population and to determine the association between CVD and various risk factors.Methods: This is a cross sectional study carried out in the rural field practice area attached to SBMCH. The study group were 400 adults (20-60 years). The data was collected using a structured questionnaire containing socio-demographic particulars, details regarding CVD risk factors and physical measurements. Data was entered in MS Excel and analysed using SPSS 15 software.Results: Prevalence of CVD is 24.3% and of which hypertension (18%), coronary artery disease (6%), stroke (2.2%) and valvular heart disease (1%). The prevalence of risk factors are age >40 (63%), tobacco use (17.8%), alcohol use (22.3%), physical inactivity (52%), unhealthy diet (61.4%), obesity (19.7%), diabetes (13.6%) and positive family history (21.4%). There is a strong statistically significant association between CVD and age (p=0.008, OR-1.968), tobacco use (p<0.0001, OR-10.029), obesity (p<0.0001, OR-13.462) and positive family history (p<0.0001, OR-13.964).Conclusions: In this study prevalence of CVD is high. It is necessary to minimize the burden of growing CVD by controlling the rates of the risky behaviours by lifestyle modification and by increasing awareness regarding CVD.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yee-How Say ◽  
Anna Hwee Sing Heng ◽  
Kavita Reginald ◽  
Yi Ru Wong ◽  
Keng Foo Teh ◽  
...  

Abstract Background Acne vulgaris, a highly prevalent multifactorial inflammatory skin disease, can be categorised into different severity and scarring grades based on the type, number, and severity of lesions. While many epidemiology studies have investigated the risk factors for acne presentation, fewer studies have specifically studied the risk factors for acne severity and scarring. Therefore, this study investigated the prevalence of acne, acne severity and scarring grades, and their associated non-modifiable and modifiable epidemiological risk factors among Malaysian Chinese. Methods A total of 1840 subjects (1117 cases/723 controls) completed an investigator-administered questionnaire as part of a cross-sectional study, which include socio-demographics, familial history, lifestyle factors, dietary habits, and acne history. Acne cases were further evaluated for their severity (n = 1051) and scarring (n = 1052) grades by a trained personnel. Results Majority of the acne cases (up to 69%) had mild acne or Grade 1/2 scarring, while 21.6% had moderate/severe acne and 5.5% had Grade 3/4 scarring. Males had significantly higher risk of presenting with higher grades of acne scarring. Those who had acne, regardless of severity and scarring grades, had strong positive familial history (either in parents and/or sibling). Frequent consumption (most or all days) of foods that are commonly consumed during breakfast (butter, probiotic drinks, cereals and milk) decreased the risk for acne presentation and higher acne scarring, while periodic consumption (once/twice per week) of nuts and burgers/fast food decreased the risk for higher acne severity. Alcohol drinking was significantly associated with increased risk for acne presentation, while paternal, parental and household smoking were associated with reduced risk of more severe acne. Conclusions In conclusion, positive familial history is a strong predisposing factor in influencing acne presentation, severity and scarring. Frequent consumption of foods that are commonly consumed during breakfast is protective against acne presentation.


2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Elio Jabra ◽  
Amal Al-Omari ◽  
Fadi Haddadin ◽  
Walid Alam ◽  
Khawlah Ammar ◽  
...  

Background. Bladder cancer (BC) is the second most reported cancer in Lebanon and the fifth in Jordan. Its risk factors are mainly smoking and occupational exposure to aromatic amines. In these countries where smoking and bladder cancer are highly prevalent, the role of waterpipe smoking (WPS) in bladder cancer is less investigated. We aim to compare two sets of patients between Lebanon and Jordan, focusing on their smoking habits, WP use, occupational exposure, and the grade/invasiveness of their bladder cancer. Methods. This is a cross-sectional study that compares the smoking culture between two sets of populations with bladder cancer, from two different countries. We recruited 274 bladder cancer patients over the 18 years of age at the American University of Beirut Medical Center (AUBMC), and 158 bladder cancer patients over the age of 18 years at the King Hussein Cancer Center (KHCC). Results. 7.7% of Lebanese patients had significantly more positive family history of bladder cancer compared to 13.9% of Jordanian patients ( p = 0.045 ). Another significant finding is that the majority of Lebanese patients 70.7% reported being frequently exposed to secondhand smoking, mainly cigarettes, versus only 48.6% of Jordanian patients ( p < 0.001 ). The increasing smoking trend among Lebanese females is remarkably the highest in the region, which contributed to the overall increase in smoking rates in the country. 17.1% of the Lebanese smoking patients are mainly but not exclusively WP smokers of which 6.3% are daily WP smokers, similarly 17.1% of the Jordanian patients of which 3.2% are daily WP smokers. There were 71.5% of Lebanese patients who had a noninvasive BC versus 40% of Jordanian patients ( p < 0.001 ), and more than one-third reported an occupational exposure to one of the risk factors of BC in both groups. Conclusions. Bladder cancer incidence is on the rise in both Jordan and Lebanon along with different smoking types. It is necessary to impose prevention policies to prevent and control the high smoking prevalence. Bladder cancer invasiveness is higher in Jordan compared to universal data.


Dermatology ◽  
2018 ◽  
Vol 235 (1) ◽  
pp. 45-50 ◽  
Author(s):  
Alejandro Molina-Leyva ◽  
Carlos Cuenca-Barrales

Background/Aims: Hidradenitis suppurativa (HS) is a chronic inflammatory and destructive skin disorder. Early diagnosis and treatment are critical to stop its progression. Data concerning adolescent-onset HS are scarce. The aims of this study are to describe the prevalence of adolescent-onset HS and to explore potential risk factors and the disease features of these patients. Patients and Methods: A cross-sectional study including 134 patients was performed. Results: Adolescent-onset HS occurred in 51.5% (69/134) of patients. Adolescent-onset HS was associated with female sex, positive family history, presence of pilonidal sinus, acne conglobata, longer disease duration and a worse perception of disease severity. Conclusion: Adolescent-onset HS might be more frequent than previously reported. Female sex, positive family history and the presence of elements of the follicular occlusion tetrad identify individuals with a higher risk of early onset. These patients experience a longer disease duration and perceive their disease as severer.


2020 ◽  
Vol 12 (2) ◽  
pp. 96-101
Author(s):  
Mohammad Ullah ◽  
Suman Kumar Saha ◽  
Md Toufiqur Rahman ◽  
Md Abdul Karim ◽  
Rashid Ahmed

Background: Incidence of noncommunicable disease, specially cardiovascular diseases, is increasing in Bangladesh. Prevalence of risk factors in ischaemic heart disease (IHD) has been studied in different tertiary hospitals and institutes. This study was done in a secondary hospital with a patient population mainly of low socioeconomic condition and was compared with other patient groups of the country and Indian subcontinent. Methods: this cross sectional study was conducted in Manikganj Sadar Hospital from July 2019 to December 2019. All the patients admitted with the diagnosis of myocardial infarction (MI) were included. Cardiovascular risk factors, like smoking, diabetes mellitus (DM), hypertension (HTN), family history of premature cardiovascular diseases, dyslipidaemia and obesity, were evaluated among the patients. Results: This cross-sectional study showed most of the patients were in the age group of 50-59 years. 66% of the male patients and 2% of the female patients were smoker. 66% of the patients were hypertensive, 44% patients were diabetic, 28.5% patients were overweight, 60.4% patients had total cholesterol > 200mg/dl, 73.6% patients had LDL>130 mg/dl, 110 76.3% patients had HDL < 40 mg/ dl, 72.2% had triglyceride >150 mg/dl and 39% patients had family history of premature cardiovascular disease. Ninety (62.5%) patients had anterior MI, 50 (34.7%) patients had inferior MI and 4 (2.7%) patients had NSTEMI. 65 patients had no major risk factor and 57 % had three or more risk factors. Conclusion: The study population was more aged in comparison to other studies conducted in different parts of Bangladesh. Prevalence of smoking habit was lower but the prevalence of HTN, DM and dyslipidaemia were higher than the general population and other cohorts of MI patients. The prevalence of major risk factors was much higher than the general population of Bangladesh. Cardiovasc. j. 2020; 12(2): 96-101


2021 ◽  
Vol 28 (Supplement_1) ◽  
Author(s):  
I Sulska ◽  
L Mishchenko ◽  
A Sorokolietova ◽  
M Hordina ◽  
S Zhulinska

Abstract Funding Acknowledgements Type of funding sources: None. Background. There is a little information on the prevalence of cardio-metabolic risk factors in the Ukrainian medical staff. The aim of investigation was to determine the abundance of certain risk factors for cardiovascular (CV) diseases among the medical personnel in the six cities of Ukraine, a study dedicated to World Heart Day 2020. Purpose. To establish the presence of cardio-metabolic risk factors among medical workers in Ukraine. Materials and methods. A hospital-based cross-sectional study including 471 participants (415 female and 56 male) between the age of 19 and 79 years surveyed. The cardio-metabolic risk markers assessed were non-modifiable risk factors (family history) and modifiable risk factors (obesity, hypertension, dyslipidemia, diabetes, prediabetes, smoking status). The prevalence of hypertension (HTN) estimated by ESC 2018 recommendations, diabetes and prediabetes by ADA 2019, ESC 2019 and body mass index WHO criteria for obesity classifications. Using standard methods were assessed: fasting glucose concentration, glycosylated hemoglobin (HbA1c) and blood lipids (total cholesterol, LDL-C, triglycerides, HDL-C). Results The median age of participants was 53,3 ± 11,77 years. Positive smoking status reported by 66 persons (14,0%). Analysis of family history showed that 51,4% of the participants had of HTN, 14,9% of myocardial infarction and 25,1% of stroke. The prevalence of modifiable risk factors: HTN registered in 51,4% cases. Around 34,8% of participants were overweight, and 34,6% were obese, 70,7% had waist circumference more than 94 cm (men) and &gt; 80 cm (woman). Prediabetes glycemic levels and diabetes incidence were 42,8% and 12,6%, accordingly. Atherogenic dyslipidemia estimated by increased level of LDL-C more than 4,9 mmol/l, which determinate high risk of CV disorders, estimated in 13,6% participants. Also high triglycerides levels were defined as those of at least 2,3 mmol/l were in 14,9%. Low level of aerobic activity (less than 150 min in week) had 33,4% participants. 30,7% of participants older than 40 years presented high CV risk and 23,9% were in very high risk. Conclusion. Cardio-metabolic risk factors prevail among medical workers in Ukraine. The results point to the relevance of public health recommendations to contribute lifestyle changes and early identification of risk factors for prevention of CV outcomes.


2003 ◽  
Vol 18 (3) ◽  
pp. 110-122 ◽  
Author(s):  
A Jawien ◽  
T Grzela ◽  
A Ochwat

Objective: To study the prevalence, clinical expression and risk factors of chronic venous insufficiency (CVI) in 40,095 Polish adults. Method: This was a multicentre cross-sectional study with 803 participating primary care physicians. Results: The study population was mainly female (84%). The mean age was 44.8 years. Of the total population, 10% presented with oedema, 34.3% had varicose veins, with approximately the same proportion in males and females and 1.5% presented with past or active ulceration. A similar prevalence of CVI to that observed in the developed countries was reported in Poland. Obesity, the number of pregnancies and a positive family history were found to be risk factors for CVI. Female gender was not shown to be a risk factor for varicose veins. Conclusions: The relationship between the presence of symptoms and signs of CVI was high, whatever the gender. Thus, the previously described dominance of the disease in females is losing its significance.


2017 ◽  
Vol 6 (4) ◽  
pp. 218-224
Author(s):  
Zata Ismah ◽  
Emma Novita

Abstrak Analisis karakteristik penderita TB selain berguna untuk pengobatan juga berguna dalam memudahkan penemukan tersangka TB. Penelitian ini bertujuan untuk menganalisis karakteristik penderita TB. Desain studi yang digunakan adalah crossectional dengan sampel sebanyak 40 pasien TB yang berobat 3 bulan terakhir di Puskesmas Seberang Ulu 1 Palembang. Pengumpulan data dilakukan dengan kunjungan rumah ke pasien lalu dilakukan wawancara serta pemeriksaan fisik dan status kesehatan.  Hasil penelitian didapatkan bahwa karakteristik penderita TB paling banyak pada kelompok : usia produktif usia 12 – 35 tahun  dan  rentang usia dewasa 49 -  61 tahun; jenis kelamin laki-laki; pendidikan sekolah tingkat dasar; pekerjaan buruh; sosial ekonomi rendah; perokok aktif. Ditemukan 13.2% pasien TB dengan DM, 45% pasien TB dengan hipertensi, 47.5% pasien TB dengan anemia, 55% pasien TB dengan gizi kurang, 17.5% pasien memiliki riwayat keluarga menderita TB. Pasien kambuh sebanyak 12.5%; pasien yang putus OAT 17.5%; serta ditemukan tidak minum OAT sebanyak 15%.   Kata kunci: Karakteristik, Deskriptif, Tuberkulosis,                            Abstracts Analysis of characteristics TB disease besides useful for treatment is also useful to finding TB cases. This study aims to analyze characteristic of TB patients. This research used cross sectional study design with 40 TB patients treated last 3 months at Puskesmas Seberang Ulu 1 Palembang. Data collection was done with patient home visits, interview, physical examination health status. The results was most of characteristic TB patients in productive age group, maximum age 35 years, male gender, primary education, occupation was coolie, low socioeconomic, active smokers. TB Patients was founded 13.2% with DM; 45% TB patients with hypertension; 47.5% TB patients with anemia; 55% TB patients with malnutrition; 17.5% of patients had a family history of TB. Patients relapsed were 12.5%; OAT dropout patients were founded 17.5%; 15% patients were not OAT.   Keywords: Characteristics, Descriptive, Tuberculosis


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