Preconception depression and anxiety symptoms and maternal-infant bonding: a 20-year intergenerational cohort study

Author(s):  
Craig A. Olsson ◽  
Elizabeth A. Spry ◽  
Yvette Alway ◽  
Margarita Moreno-Betancur ◽  
George Youssef ◽  
...  
2021 ◽  
Author(s):  
Margaret T Anton ◽  
Heidi Mochari-Greenberger ◽  
Evie Andreopoulos ◽  
Reena L Pande

BACKGROUND Digital solutions, such as web-based and mobile interventions, have the potential to streamline pathways to mental health services and improve access to mental health care. Although there are a growing number of randomized trials establishing the efficacy of digital interventions for common mental health problems, less is known about the real world impact of these tools. AbleTo Digital+, a commercially available mental health application for depression and anxiety, offers a unique opportunity to understand the clinical impact of such tools delivered in real world contexts. OBJECTIVE The primary objective of this study was to examine the magnitude of change in depression and anxiety symptoms among individuals who used AbleTo Digital+ programs, as well as to evaluate Digital+ module completion and use of 1:1 coaching. METHODS In this retrospective cohort study, we analyzed previously collected and permanently de-identified data from a consecutive cohort of 1,896 adults who initiated use in one of the three Digital+ eight-module programs (Depression, Generalized Anxiety, or Social Anxiety) between January 1 and June 30, 2020. Depression, generalized anxiety, and social anxiety symptoms were assessed within each program using the Patient Health Questionnaire-9 (PHQ-9), the Generalized Anxiety Disorder-7 (GAD-7), and the Social Phobia Inventory (SPIN) respectively. Linear mixed effects models were built to assess the association between module completion and symptom change among users who completed at least four modules and had at least mild baseline symptom elevations, controlling for age, gender, and baseline symptom severity. Digital+ use, including module completion, 1:1 coaching calls, and in-app coach messaging were also evaluated. RESULTS Large effects were observed among Depression (d=1.5), Generalized Anxiety (d=1.2), and Social Anxiety (d=1.0) program participants who completed at least four modules and had mild baseline elevations (n=470). Associations between module completion and change in depression (????=-1.2; P<.001), generalized anxiety (????=-1.1; P<.001), and social anxiety (????=-2.4; P<.0001) symptom scores retained significance with covariate adjustment. Participants completed an average of 2.6 (SD=2.7) modules. The average total length of app use was 7.5 weeks (SD=11.9). Approximately two-thirds of users engaged in 1:1 coaching calls (66.8%) or in-app text messaging (66.10%). Participants who completed at least four modules participated in significantly more coaching calls per module (M=1.1; SD=0.7)than users who completed fewer than four modules (M=1.0; SD=1.2; t=-2.1, P=.03). CONCLUSIONS This study demonstrated that AbleTo Digital+ users experienced significant reductions in depression, generalized anxiety, and social anxiety symptoms over the course of the program.


2016 ◽  
Vol 20 (1) ◽  
pp. 39-48 ◽  
Author(s):  
Linnea Karlsson ◽  
Niko Nousiainen ◽  
Noora M. Scheinin ◽  
Mikael Maksimow ◽  
Marko Salmi ◽  
...  

2007 ◽  
Author(s):  
David Watson ◽  
Michael W. O’Hara ◽  
Leonard J. Simms ◽  
Roman Kotov ◽  
Michael Chmielewski ◽  
...  

2008 ◽  
Vol 22 (3) ◽  
pp. 271-288 ◽  
Author(s):  
Megan E. Hughes ◽  
Lauren B. Alloy ◽  
Alex Cogswell

The relation between repetitive thought and depression and anxiety symptoms was examined in an undergraduate sample. Individuals completed self-report measures of rumination, worry, depression, and anxiety as well as other related constructs including private self-consciousness, looming maladaptive style, cognitive style, cognitive content, and future outlook. Regression analyses and tests for significant differences between partial correlations were utilized to assess the study hypotheses. The results indicated that rumination and worry overlap in their association with depression and anxiety symptoms, and that rumination may be an especially important component of this overlap. Secondary analyses demonstrated that rumination and worry are two distinct constructs, as their patterns of associations with related constructs were different.


2021 ◽  
Vol 4 ◽  
pp. 100098
Author(s):  
Jerome Sarris ◽  
Daniel Perkins ◽  
Lachlan Cribb ◽  
Violeta Schubert ◽  
Emerita Opaleye ◽  
...  

2021 ◽  
pp. 1-10
Author(s):  
Jan Stochl ◽  
Emma Soneson ◽  
Freya Stuart ◽  
Jessica Fritz ◽  
Annabel E. L. Walsh ◽  
...  

Abstract Background Despite evidence for the general effectiveness of psychological therapies, there exists substantial heterogeneity in patient outcomes. We aimed to identify factors associated with baseline severity of depression and anxiety symptoms, rate of symptomatic change over the course of therapy, and symptomatic recovery in a primary mental health care setting. Methods Using data from a service evaluation involving 35 527 patients in England's psychological and wellbeing [Improving Access to Psychological Therapies (IAPT)] services, we applied latent growth models to explore which routinely-collected sociodemographic, clinical, and therapeutic variables were associated with baseline symptom severity and rate of symptomatic change. We used a multilevel logit model to determine variables associated with symptomatic recovery. Results Being female, younger, more functionally impaired, and more socioeconomically disadvantaged was associated with higher baseline severity of both depression and anxiety symptoms. Being older, less functionally impaired, and having more severe baseline symptomatology was associated with more rapid improvement of both depression and anxiety symptoms (male gender and greater socioeconomic disadvantage were further associated with rate of change for depression only). Therapy intensity and appointment frequency seemed to have no correlation with rate of symptomatic improvement. Patients with lower baseline symptom severity, less functional impairment, and older age had a greater likelihood of achieving symptomatic recovery (as defined by IAPT criteria). Conclusions We must continue to investigate how best to tailor psychotherapeutic interventions to fit patients’ needs. Patients who begin therapy with more severe depression and/or anxiety symptoms and poorer functioning merit special attention, as these characteristics may negatively impact recovery.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Bo Zhang ◽  
Qin Wang ◽  
Xuancan Zhang ◽  
Li Jiang ◽  
Lezhi Li ◽  
...  

Abstract Background This study aimed at investigating: 1) the relationship between self-care agency and depression and anxiety; 2) the sociodemographic and clinical factors associated with depression and anxiety in patients with diabetic retinopathy (DR) in China. Methods A cross-sectional study was conducted. One-hundred and five patients with DR were recruited. Self-care agency was assessed by the exercise of self-care agency (ESCA) scale. Depression and anxiety were assessed by the hospital anxiety and depression scale (HADS-D and HADS-A). Pearson or Spearman correlations were performed to assess the association between self-care agency and depression and anxiety. Stepwise multivariate linear regression analyses were conducted to assess the contribution of the sociodemographic and clinical factors to depression and anxiety. Results Thirty-six (34.3%) and 43 (41.1%) patients exhibited depressive and anxiety symptoms, respectively. Only 24 (22.9%) patients showed a high self-care agency. The ESCA total and subscale scores were negatively correlated depressive symptoms (P < 0.05). Self-care skills were negatively correlated with anxiety symptoms (P < 0.05). ESCA total score, rural residence, history of hypertension and visual acuity were associated with depression; self-care skills and diastolic blood pressure were associated with anxiety. Conclusions Self-care agency negatively correlates with depression and anxiety in patients with DR. Special attention should be paid to patients living in rural areas and/or those having a history of hypertension when assessing depression and anxiety in patients with DR. Future studies are needed to clarify the causal relationship between self-care agency and depression and anxiety.


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