Eating Disorders in ‘Millennials’: Risk Factors and Treatment Strategies in the Digital Age

2019 ◽  
Vol 48 (1) ◽  
pp. 46-53
Author(s):  
Cassandra Lenza
Keyword(s):  
Risk Factors ◽  
Eating Disorders ◽  
Treatment Strategies ◽  
Digital Age

Predictors of dropout from inpatient treatment for eating disorders

2011 ◽  
Vol 26 (S2) ◽  
pp. 716-716 ◽  
Author(s):  
S. Catellani ◽  
F. Arnone ◽  
E. De Bernardis ◽  
S. Ferrari ◽  
L. Pingani ◽  
...  
Keyword(s):  
Risk Factors ◽  
Eating Disorders ◽  
Inpatient Treatment ◽  
Protective Factor ◽  
Treatment Strategies ◽  
Drop Out ◽  
Self Report ◽  
Psychometric Tests ◽  
Improve Treatment ◽  
Catholic Religion

IntroductionDrop-out from treatment for Eating Disorders is increasing (Campbell; 2007), and it is a risk factor for relapse and more chronic and severe course of the illness (Fassino et al.; 2009). Drop-out can be caused by interaction of concurrent, individual, familiar ad environmental factors (Sly; 2009).Aim of the studyTo examine possible risk factors of drop-out from inpatient treatment for eating disorders.Materials and methodsThe sample included 41 patients who voluntarily left the treatment before completion (’droppers’) and 88 patients who completed it (’completers’), in the period between 1st January 2006 and 31st December 2009 at Villa Maria Luigia Hospital (Monticelli Terme, PR, Italy). Patients were administered 2 self-report questionnaires and 3 psychometric tests: Eating Disorders Questionnaire, Predisposing, bringing on and maintaining risk factors for eating disorders, EDI-II, BUT, SCL-90.ResultsDroppers appear to be more aggressive (p = 0.022), get worse scholastic results (p = 0.016) and have less friendships and less social interaction (p = 0.021). Parental break-up (p = 0.015), moving house (p = 0.006), father's death (p = 0.005), abortition (p = 0.040), father's alcohol abuse (p = 0.011) and a mother who suffers of eating disorder (p = 0.008) are more frequent in droppers than completers. Catholic religion seems to be a protective factor from drop-out (p = 0.005).ConclusionDrop-out is a multifactor phenomenon; identification of risk factors can improve treatment strategies and outcome.

scholarly journals Overlap time is an independent risk factor of radiation pneumonitis for patients treated with simultaneous EGFR-TKI and thoracic radiotherapy

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Wenxiao Jia ◽  
Qianqian Gao ◽  
Min Wang ◽  
Ji Li ◽  
Wang Jing ◽  
...  
Keyword(s):  
Risk Factors ◽  
First Generation ◽  
Kinase Inhibitors ◽  
Radiation Pneumonitis ◽  
Cell Cancer ◽  
Treatment Strategies ◽  
Thoracic Radiotherapy ◽  
Ipsilateral Lung ◽  
Nsclc Patients ◽  
Egfr Tki

Abstract Background The exact rate and relevant risk factors of radiation pneumonitis (RP) for non-small-cell cancer (NSCLC) patients treated with the combination of epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) and thoracic radiotherapy have not been reported. Thus, this study aimed to investigate the rate and risk factors of RP for EGFR-positive NSCLC patients simultaneously treated with first-generation EGFR-TKI and TRT. Patients and methods We retrospectively evaluated NSCLC patients simultaneously treated with first-generation EGFR-TKI and thoracic radiotherapy between January 2012 and December 2019 at Shandong Cancer Hospital and Institute, Shandong, China. RP was diagnosed via computed tomography and was classified according to the Common Terminology Criteria for Adverse Events v5.0. The risk factors of RP were identified using uni- and multivariate analyses. Results Of the 67 patients included, 44.78% (30/67) developed grade ≥ 2 RP. Grade ≥ 2 RP occurred within a median of 3.48 (range 1.07–13.6) months. The EGFR-TKI icotinib, ipsilateral lung V30 > 34%, and overlap time of > 20 days between EGFR-TKI and thoracic radiotherapy were identified to be independent predictive factors of grade ≥ 2 RP. Conclusions Grade ≥ 2 RP is highly frequent in NSCLC patients simultaneous treated with first-generation EGFR-TKI and thoracic radiotherapy. Icotinib, ipsilateral lung V30 ≤ 34%, and overlap time of ≤ 20 days for EGFR-TKI and thoracic radiotherapy will be helpful to lower the risk of RP in these patients. The addition of thoracic radiotherapy should be cautious, and the treatment strategies can be optimized to reduce the rate of RP for patients treat with simultaneous EGFR-TKI and thoracic radiotherapy.

scholarly journals An Evolutionary Genetic Perspective of Eating Disorders

2017 ◽  
Vol 106 (3) ◽  
pp. 292-306 ◽  
Author(s):  
Alexandra J. Mayhew ◽  
Marie Pigeyre ◽  
Jennifer Couturier ◽  
David Meyre
Keyword(s):  
Risk Factors ◽  
Eating Disorders ◽  
Family Environment ◽  
Genetic Risk ◽  
Cultural Influences ◽  
Gene Variants ◽  
Biological Mechanisms ◽  
Binary Variable ◽  
Evolutionary Genetic ◽  
New Perspective

Eating disorders (ED) including anorexia nervosa (AN), bulimia nervosa (BN), and binge eating disorder (BED) affect up to 5% of the population in Western countries. Risk factors for developing an ED include personality traits, family environment, gender, age, ethnicity, and culture. Despite being moderately to highly heritable with estimates ranging from 28 to 83%, no genetic risk factors have been conclusively identified. Our objective was to explore evolutionary theories of EDs to provide a new perspective on research into novel biological mechanisms and genetic causes of EDs. We developed a framework that explains the possible interactions between genetic risk and cultural influences in the development of ED. The framework includes three genetic predisposition categories (people with mainly AN restrictive gene variants, people with mainly BED variants, and people with gene variants predisposing to both diseases) and a binary variable of either the presence or absence of pressure to be thin. We propose novel theories to explain the overlapping characteristics of the subtypes of AN (binge/purge and restrictive), BN, and BED. For instance, mutations/structural gene variants in the same gene causing opposite effects or mutations in nearby genes resulting in partial disequilibrium for the genes causing AN (restrictive) and BED may explain the overlap of phenotypes seen in AN (binge/purge).

Avascular Osteonecrosis of the Talus: Current Treatment Strategies

2021 ◽  
pp. 107110072110510
Author(s):  
Hanci Zhang ◽  
Amanda N. Fletcher ◽  
Daniel J. Scott ◽  
James Nunley
Keyword(s):  
Risk Factors ◽  
Clinical Diagnosis ◽  
Treatment Strategies ◽  
Core Decompression ◽  
Bone Grafts ◽  
Current Treatment ◽  
Optimal Treatment ◽  
Patient Specific ◽  
Avascular Osteonecrosis ◽  
Current Trends

Avascular osteonecrosis (AVN) of the talus (AVNT) is a painful and challenging clinical diagnosis. AVNT has multiple known risk factors and etiologies and presents at different stages in severity. Given these unique factors, the optimal treatment solution has yet to be determined. Both joint-preserving and joint-sacrificing procedures are available, including core decompression and arthrodeses. Recently, new salvage and replacement techniques have been described including vascularized pedicle bone grafts and total talus replacement using patient-specific prosthesis; however, evidence remains limited. This review examines the current trends AVNT treatment and the emerging data behind these novel techniques.

Risk factors for hyperperfusion-induced intracranial hemorrhage after carotid artery stenting in patients with symptomatic severe carotid stenosis evaluation

2018 ◽  
Vol 11 (5) ◽  
pp. 474-478 ◽  
Author(s):  
Lei Zhang ◽  
Dongwei Dai ◽  
Zifu Li ◽  
Guoli Duan ◽  
Yong-wei Zhang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Carotid Artery ◽  
Carotid Stenosis ◽  
Intracranial Hemorrhage ◽  
Carotid Artery Stenting ◽  
Ct Perfusion ◽  
Treatment Strategies ◽  
Imaging Features ◽  
Anterior Circulation ◽  
Total Occlusion

BackgroundAnalyzing risk factors for hyperperfusion-induced intracranial hemorrhage (HICH) after carotid artery stenting (CAS) in patients with symptomatic severe carotid stenosis.MethodsThis study retrospectively analyzed clinical data of 210 patients, who had symptomatic severe carotid stenosis (70–99%) and received CAS treatment between June 2009 and June 2015, and evaluated the relationship of HICH with patients’ clinical baseline data, imaging features, and treatment strategies.ResultsSeven patients (3.3%) developed HICH after CAS. The incidence of HICH among patients with near total occlusion was significantly higher than among those without (10.1% vs 0%, P<0.001). Out of the seven, five had no development of either anterior or posterior circulations, and two had no development of anterior circulation and poor development of posterior circulation. Results showed that patients with poor compensation of Willis’ Circle were more likely to develop HICH compared with other patients (P<0.001). All patients received preoperative CT perfusion. TTP index was defined as the TTP ratio between the affected and contralateral side. The results showed that the TTP index was significantly different between the HICH group and non-HICH group (1.15±0.10 vs 1.30±0.15, P<0.001). An analysis of the ROC curve indicated that patients with TTP index >1.22 were more likely to develop HICH compared with other patients (sensitivity 100%, specificity 75.9%).ConclusionsPatients with severe unilateral carotid stenosis, the presence of near total occlusion, poor compensation of Willis’ Circle, and preoperative TTP index>1.22, have a higher risk of developing HICH after CAS.

scholarly journals ERECTILE DYSFUNCTION AND ITS PHARMACOLOGY: AN OVERVIEW

2017 ◽  
Vol 10 (2) ◽  
pp. 17 ◽  
Author(s):  
Sunil Kumar Patnaik ◽  
Haritha Polimati ◽  
Rajeswara Rao Pragada
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Erectile Dysfunction ◽  
Cigarette Smoking ◽  
Penile Erection ◽  
Treatment Strategies ◽  
Phosphodiesterase Inhibitors ◽  
Current Treatment ◽  
Complex Nature ◽  
Factors Associated

It has been estimated that currently over 150 million men worldwide suffer from erectile dysfunction (ED) and by 2025, the figure will increase beyond 322 millions. ED is the inability to achieve, and/or maintain penile erection sufficient for satisfactory sexual intercourse, and was previously regarded as the part of aging. It is associated with certain diseases and life style habits with a cause-effect relationship, including diabetes mellitus, hypertension, dyslipidemia, and cigarette smoking. Internationally, most of the men with ED fail to pursue treatment due to the complex nature of sexuality, taboos, cultural restrictions, and acceptance of ED as a normal sequel of aging. In this review, we discussed the physiology, diagnosis, and risk factors associated with ED and current treatment strategies for ED.Keywords: Erectile dysfunction, Diabetes, Penile erection, Phosphodiesterase inhibitors.

scholarly journals Eating disorders among university students: a public health challenge. An European study

2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
J Ladner ◽  
A Lukács ◽  
I Brumboiu ◽  
E Ciobanu ◽  
C Croitoru ◽  
...  
Keyword(s):  
Public Health ◽  
Higher Education ◽  
Risk Factors ◽  
Eating Disorders ◽  
Alcohol Abuse ◽  
University Students ◽  
Emotional Health ◽  
Female Gender ◽  
Behavioural Risk Factors ◽  
High Prevalence

Abstract Background Eating disorders (ED) and behavioural risk factors among students in higher education remain to be investigated. The aim of the study was to identify the prevalence of ED and the behavioural factors associated with ED in university students in four European universities: Chisinau (Ch) in Republic of Moldava, Cluj-Napoca (CN) in Romania, Miskolc (Ms) in Hungary and Rouen (R) in France. Methods In the four countries, students in higher education completed an anonymous standardized self-questionnaire, from 2016 to 2018. The questionnaire collected age, gender (M, W), housing, curricula, smoking, cannabis consumption, alcohol abuse problems (ADOSPA test), and perceived stress (Cohen score). The Sick, Control, One stone, Fat, Food (SCOFF scale) screening test was used to identify student with ED. Results A total of 3076 students were included, 705 in Ch, 582 in CL, 534 in Ms and 1255 in R. The sex-ratio was M:F=0.31 Ch, 0.30 in CN, 0.44 in Ms and 0.66 in R. The mean age was 21.2 (SD = 3.98) in Ch, 21.2 (SD = 3.2) in CL, 23.8 (SD = 5.1) in Ms and 20.0 (SD = 3.4) in R. The global prevalence of ED was 23.8%. According to the gender, the prevalence of ED in the four universities was 14.7% in M and 38.3% in W in Ch, 21.8% in M and 24.7% in W in CN, 19.7% in M and 21.4% in W in Ms and 16.1% in M and 34.0% in W in R (p &lt; 10-4). After logistic regression, significant positive relation between the positive SCOFF was observed with female gender, alcohol abuse problems and stress level. Conclusions ED prevalence patterns were quite similar in the four countries, with high prevalence of ED, even in men. Associated behavioural risk-factors were quite similar. It might be necessary in the future to screen students for potential ED upon entry to the university and also to inform student about the risk of ED and advise them to consult a healthcare professional. Key messages Our study highlights the high prevalence of eating disorders, with similar behaviours in university students in four countries. Because of the detrimental effects of ED on physical and emotional health, it seems mandatory to set up public health programs (health promotion, prevention).

Undue influence of weight and shape: is it distinct from body dissatisfaction and concern about weight and shape?

2010 ◽  
Vol 41 (4) ◽  
pp. 819-828 ◽  
Author(s):  
T. D. Wade ◽  
G. Zhu ◽  
N. G. Martin
Keyword(s):  
Risk Factors ◽  
Eating Disorders ◽  
Body Dissatisfaction ◽  
Environmental Risk ◽  
Self Esteem ◽  
Structured Interview ◽  
Environmental Risk Factors ◽  
Self Report ◽  
Undue Influence ◽  
Diagnostic Criterion

BackgroundThree cognitive constructs are risk factors for eating disorders: undue influence of weight and shape, concern about weight and shape, and body dissatisfaction (BD). Undue influence, a diagnostic criterion for eating disorders, is postulated to be closely associated with self-esteem whereas BD is postulated to be closely associated with body mass index (BMI). We understand less about the relationships with concern about weight and shape. The aim of the current investigation was examine the degree of overlap across these five phenotypes in terms of latent genetic and environmental risk factors in order to draw some conclusions about the similarities and differences across the three cognitive variables.MethodA sample of female Australian twins (n=1056, including 348 complete pairs), mean age 35 years (s.d.=2.11, range 28–40), completed a semi-structured interview about eating pathology and self-report questionnaires. An independent pathways model was used to investigate the overlap of genetic and environmental risk factors for the five phenotypes.ResultsIn terms of variance that was not shared with other phenotypes, self-esteem emerged as being separate, with 100% of its variance unshared with the other phenotypes, followed by undue influence (51%) and then concern (34%), BD (28%) and BMI (32%).ConclusionsIn terms of shared genetic risk, undue influence and concern were more closely related than BD, whereas BMI and BD were found to share common sources of risk. With respect to environmental risk factors, concern, BMI and BD were more closely related to each other than to undue influence.

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