Lower Serum Level of Adiponectin Is Associated with Increased Risk of Endoscopic Erosive Gastritis

2011 ◽  
Vol 56 (8) ◽  
pp. 2354-2360 ◽  
Author(s):  
Shunsuke Yamamoto ◽  
Kenji Watabe ◽  
Shusaku Tsutsui ◽  
Shinichi Kiso ◽  
Toshimitsu Hamasaki ◽  
...  
Keyword(s):  
Serum Level ◽  
Erosive Gastritis ◽  
Lower Serum ◽  
Increased Risk ◽  
Lower Serum Level

scholarly journals Phosphate clearance in peritoneal dialysis

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Malgorzata Debowska ◽  
Rafael Gomez ◽  
Joyce Pinto ◽  
Jacek Waniewski ◽  
Bengt Lindholm
Keyword(s):  
Peritoneal Dialysis ◽  
Serum Level ◽  
Phosphorus Removal ◽  
Serum Levels ◽  
Phosphate Removal ◽  
Dialysis Therapy ◽  
Lower Serum ◽  
Factors Associated ◽  
Lower Serum Level ◽  
Phosphate Control

Abstract In renal failure, hyperphosphatemia is common and correlates with increased mortality making phosphate removal a key priority for dialysis therapy. We investigated phosphate clearance, removal and serum level, and factors associated with phosphate control in patients undergoing continuous ambulatory (CAPD), continuous cyclic (CCPD) and automated (APD) peritoneal dialysis (PD). In 154 prevalent PD patients (mean age 53.2 ± 17.6 year, 59% men, 47% anuric), 196 daily collections of urine and 368 collections of dialysate were evaluated in terms of renal, peritoneal and total (renal plus peritoneal) phosphorus removal (g/week), phosphate and creatinine clearances (L/week) and urea KT/V. Dialytic removal of phosphorus was lower in APD (1.34 ± 0.62 g/week) than in CAPD (1.89 ± 0.73 g/week) and CCPD (1.91 ± 0.63 g/week) patients; concomitantly, serum phosphorus was higher in APD than in CAPD (5.55 ± 1.61 vs. 4.84 ± 1.23 mg/dL; p < 0.05). Peritoneal and total phosphate clearances correlated with peritoneal (rho = 0.93) and total (rho = 0.85) creatinine clearances (p < 0.001) but less with peritoneal and total urea KT/V (rho = 0.60 and rho = 0.65, respectively, p < 0.001). Phosphate removal, clearance and serum levels differed between PD modalities. CAPD was associated with higher peritoneal removal and lower serum level of phosphate than APD.

A lower serum level of middle-molecular-weight adiponectin is a risk factor for endometrial cancer

2013 ◽  
Vol 19 (4) ◽  
pp. 667-673 ◽  
Author(s):  
Yukari Ohbuchi ◽  
Yasunobu Suzuki ◽  
Ikuo Hatakeyama ◽  
Yoshifumi Nakao ◽  
Atsuya Fujito ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Endometrial Cancer ◽  
Risk Factor ◽  
Serum Level ◽  
Lower Serum ◽  
Lower Serum Level

scholarly journals Association of potato and other starchy vegetable consumption with cardiovascular diseases risk factors in Iranian elderly men

2020 ◽  
Author(s):  
Mursal Basiry ◽  
Elnaz Daneshzad ◽  
Hadis Mozaffari ◽  
Leila Azadbakht
Keyword(s):  
Risk Factors ◽  
Cardiovascular Diseases ◽  
Serum Level ◽  
Vegetable Consumption ◽  
Cvd Risk Factors ◽  
Elderly Men ◽  
Cvd Risk ◽  
Lower Serum ◽  
Lower Serum Level ◽  
Potato Consumption

Abstract Objectives. Given the limited research on potato and other starchy vegetable consumption with cardiovascular diseases (CVD), we examined the association of potato and other starchy vegetable intakes in association with cardiovascular risk factors and inflammatory biomarkers among elderly men. Study Design. A cross-sectional study. Methods. In this study, 357 elderly men were participated. Dietary intake was assessed using food a valid and reliable frequency questionnaires. Two separated groups were considered. 1. Potato, 2. Other Starchy vegetables including corn, squash, green pea, and green lima beans. CVD risk factors including HDL, LDL, FBS, TG, TC, Alkaline phosphatase, Fibrinogen, Insulin, IL-6, TNF-α, SGOT and SGPT were measured. Results. Participants in the highest tertile of potato consumption had a 45% lower serum level of fasting blood sugar (OR: 0.55; 95%CI: 0.31, 1.97; P trend: 0.041). However, this significant association disappeared after controlling for confounders. The participants in the highest tertile of potato consumption had higher serum level of triglyceride (OR: 4.52 95%CI: 1.10, 18.56; P trend: 0.030). Moreover, participants in the highest tertiles of other starchy vegetable consumption had an 84% lower serum level of alanine aminotransferase (OR: 0.16 95%CI: 0.03, 0.90; P trend: 0.040). Conclusion. Overall, more consumption of potato may be related to developing CVD risk factors. Future research is needed to elucidate the association between potato and other starchy vegetable consumption with cardiovascular diseases risk factors in both genders.

scholarly journals Severe Fatigue and Memory Impairment Are Associated with Lower Serum Level of Anti-SARS-CoV-2 Antibodies in Patients with Post-COVID Symptoms

2021 ◽  
Vol 10 (19) ◽  
pp. 4337
Author(s):  
Tihamer Molnar ◽  
Reka Varnai ◽  
Daniel Schranz ◽  
Laszlo Zavori ◽  
Zoltan Peterfi ◽  
...  
Keyword(s):  
Serum Level ◽  
Memory Impairment ◽  
Disease Onset ◽  
Strongly Correlated ◽  
Lower Serum ◽  
Time Points ◽  
Persistent Symptoms ◽  
Severe Fatigue ◽  
Lower Serum Level

Background: Post-COVID manifestation is defined as persistent symptoms or long-term complications beyond 4 weeks from disease onset. Fatigue and memory impairment are common post-COVID symptoms. We aimed to explore associations between the timeline and severity of post-COVID fatigue and anti-SARS-CoV-2 antibodies. Methods: Fatigue and memory impairment were assessed in a total of 101 post-COVID subjects using the Chalder fatigue scale (CFQ-11) and a visual analogue scale. Using the bimodal scoring system generated from CFQ-11, a score ≥4 was defined as severe fatigue. Serum anti-SARS-CoV-2 spike (anti-S-Ig) and nucleocapsid (anti-NC-Ig) antibodies were examined at two time points: 4–12 weeks after onset of symptoms, and beyond 12 weeks. Results: The serum level of anti-S-Ig was significantly higher in patients with non-severe fatigue compared to those with severe fatigue at 4–12 weeks (p = 0.006) and beyond 12 weeks (p = 0.016). The serum level of anti-NC-Ig remained high in patients with non-severe fatigue at both time points. In contrast, anti-NC-Ig decreased significantly in severe fatigue cases regardless of the elapsed time (4–12 weeks: p = 0.024; beyond 12 weeks: p = 0.005). The incidence of memory impairment was significantly correlated with lower anti-S-Ig levels (−0.359, p < 0.001). Conclusion: The systemic immune response reflected by antibodies to SARS-CoV-2 is strongly correlated with the severity of post-COVID fatigue.

Lower Serum Level of Ferritin in Patients with H. Pylori Infection Is Improved by H. pylori Eradication Without Affecting Daily Intake of Iron and Vitamin C

2016 ◽  
Vol 111 ◽  
pp. S419
Author(s):  
Satoru Nakagawa ◽  
Tadashi Shimoyama ◽  
Daisuke Chinda ◽  
Satoshi Sato ◽  
Shigeyuki Nakaji ◽  
...  
Keyword(s):  
Serum Level ◽  
Vitamin C ◽  
Daily Intake ◽  
Lower Serum ◽  
Lower Serum Level ◽  
H Pylori

Clinical and genetic analysis of KATP variants with heart failure risk in patients with decreased serum ApoA-I levels

2021 ◽  
Author(s):  
Cheng Liu ◽  
Yanxian Lai ◽  
Jingxian Pei ◽  
Huiling Huang ◽  
Junfang Zhan ◽  
...  
Keyword(s):  
Heart Failure ◽  
Potassium Channels ◽  
Vascular Reactivity ◽  
Expression Profiles ◽  
Channel Coupling ◽  
Lower Serum ◽  
Increased Risk ◽  
High Degree ◽  
Generation Sequencing

Abstract Context Lower serum concentration of apolipoprotein A-I (ApoA-I) is causally associated with heart failure (HF) risk. ATP-sensitive potassium channels (KATP), as a gating channel coupling vascular reactivity and metabolism with ischemic protection, become a new potential target of management for HF. The KATP gene sequence is highly polymorphic and high degree of genetic heterogeneity. Objective To determine whether ATP-sensitive potassium channels (KATP) variants predict the risks of decreased ApoA-I concentration and its related HF. Design, Patients, Settings A total of 634 subjects, including 317 subjects with decreased ApoA-I concentration (&lt; 120 mg/dL) and 317 counterpart subjects (≥ 120 mg/dL), were retrospectively selected. Methods 5 KATP variants were genotyped through MassARRAY platform. The exosome-derived microRNAs (exo-miRs) expression profiles were identified by next-generation sequencing, and the top 10 DE exo-miRs were verified using qPCR in a validation cohort of 240 subjects with decreased ApoA-I concentration. Results KATP rs141294036 was related to increased risk of lower ApoA-I levels (adjusted OR=1.95, P=0.002) and HF incidence (adjusted OR=2.38, P=0.009), especially HFpEF (adjusted OR=2.13, P=0.015). After median 48.6-months follow-up, participants carrying CC genotype of rs141294036 was associated with elevated HF re-hospitalization risk (adjusted HR=1.91, P=0.005). 36 exo-miRs were significantly differentially expressed between different genotypes of rs141294036 in subjects with lower ApoA-I levels, but only 5 exo-miRs (miR-31-5p, miR-126-5p, miR-106a-5p, miR-378i and miR-181c-5p) were further confirmed. Conclusions The KATP rs141294036 was associated with increased risks of lower ApoA-I levels, HF incidence (especially HFpEF) and HF re-hospitalization, involving in those 5 confirmed exo-miRs and its related metabolic pathways.

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