Highly stretchable gamma-irradiated poly (vinyl alcohol)/Tannic acid composite hydrogels with superior transparency and antibacterial activity

We investigated the mechanical and structural properties of composite hydrogels composed of chitosan nanofiber (ChsNF), positively charged alumina-coated silica (ac-SiO2) nanoparticles, carboxylated poly (vinyl alcohol) (cPVA), and borax. ChsNF/cPVA/borax hydrogels without ac-SiO2 exhibited high Young’s modulus but poor elongation, whereas cPVA/ac-SiO2/borax hydrogels without ChsNF had moderate Young’s modulus but high elongation. ChsNF/ac-SiO2/cPVA/borax hydrogels using both ChsNF and ac-SiO2 as reinforcement agents exhibited high extensibility (930%) and high Young′s modulus beyond 1 MPa at a high ac-SiO2 concentration. The network was formed by multiple crosslinking such as the complexation between borate and cPVA, the ionic complexation between ac-SiO2 and cPVA, and the hydrogen bond between ChsNF and cPVA. Structural analysis by synchrotron small-angle X-ray scattering revealed that the nanostructural inhomogeneity in ChsNF/ac-SiO2/cPVA/borax hydrogel was suppressed compared to those of the ChsNF/cPVA/borax and cPVA/ac-SiO2/borax hydrogels.

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The Design, Characterization and Antibacterial Activity of Heat and Silver Crosslinked Poly(Vinyl Alcohol) Hydrogel Forming Dressings Containing Silver Nanoparticles

Nanomaterials ◽

10.3390/nano11010096 ◽

2021 ◽

Vol 11 (1) ◽

pp. 96

Author(s):

John Jackson ◽

Helen Burt ◽

Dirk Lange ◽

In Whang ◽

Robin Evans ◽

...

Keyword(s):

Silver Nanoparticles ◽

Antibacterial Activity ◽

Silver Nitrate ◽

Vinyl Alcohol ◽

Unmet Need ◽

Chemical Characterization ◽

Wound Dressings ◽

Poly Vinyl Alcohol ◽

Burn Wound

The prompt treatment of burn wounds is essential but can be challenging in remote parts of Africa, where burns from open fires are a constant hazard for children and suitable medical care may be far away. Consequently, there is an unmet need for an economical burn wound dressing with a sustained antimicrobial activity that might be manufactured locally at low cost. This study describes and characterizes the novel preparation of a silver nitrate-loaded/poly(vinyl alcohol) (PVA) film. Using controlled heating cycles, films may be crosslinked with in situ silver nanoparticle production using only a low heat oven and little technical expertise. Our research demonstrated that heat-curing of PVA/silver nitrate films converted the silver to nanoparticles. These films swelled in water to form a robust, wound-compatible hydrogel which exhibited controlled release of the antibacterial silver nanoparticles. An optimal formulation was obtained using 5% (w/w) silver nitrate in PVA membrane films that had been heated at 140 °C for 90 min. Physical and chemical characterization of such films was complemented by in vitro studies that confirmed the effective antibacterial activity of the released silver nanoparticles against both gram positive and negative bacteria. Overall, these findings provide economical and simple methods to manufacture stable, hydrogel forming wound dressings that release antibiotic silver over prolonged periods suitable for emergency use in remote locations.

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Electrospun synthesis of silver/poly (vinyl alcohol) nano-fibers: Investigation of microstructure and antibacterial activity

Materials Letters ◽

10.1016/j.matlet.2021.131370 ◽

2022 ◽

Vol 309 ◽

pp. 131370

Author(s):

Sara Azarakhsh ◽

Hamed Bahiraei ◽

Gholamhosain Haidari

Keyword(s):

Antibacterial Activity ◽

Vinyl Alcohol ◽

Poly Vinyl Alcohol

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Porous boron nitride nanofibers as effective nanofillers for poly(vinyl alcohol) composite hydrogels with excellent self-healing performances

Soft Matter ◽

10.1039/d1sm01361k ◽

2022 ◽

Author(s):

Xiangqian Gao ◽

Tiantian Deng ◽

Xindi Huang ◽

Mengmeng Yu ◽

Danyang Li ◽

...

Keyword(s):

Boron Nitride ◽

Vinyl Alcohol ◽

Poly Vinyl Alcohol ◽

Self Healing ◽

One Pot ◽

One Dimensional ◽

Composite Hydrogels ◽

Assembly Method

A new composite hydrogels with excellent self-healing properties was prepared by combining poly(vinyl alcohol) (PVA) and boron nitride nanofibers (BNNFs) via a facile one-pot assembly method. One-dimensional porous BNNFs with...

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Influences of processing and sterilizing strategies on reduced silver nanoparticles in poly(vinyl alcohol) electrospun membranes: Optimization and preservation of antibacterial activity

Materials Chemistry and Physics ◽

10.1016/j.matchemphys.2020.123300 ◽

2020 ◽

Vol 254 ◽

pp. 123300 ◽

Cited By ~ 1

Author(s):

Wen-Cheng Chen ◽

Chia-Ying Ko ◽

Kai-Chi Chang ◽

Chih-Hua Chen

Keyword(s):

Silver Nanoparticles ◽

Antibacterial Activity ◽

Vinyl Alcohol ◽

Poly Vinyl Alcohol ◽

Electrospun Membranes

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Novel composite hydrogels containing fractionated, purified lignins for aqueous-based separations

Journal of Materials Chemistry A ◽

10.1039/d0ta09046h ◽

2021 ◽

Author(s):

Nicholas Gregorich ◽

Junhuan Ding ◽

Mark C. Thies ◽

Eric M. Davis

Keyword(s):

Molecular Weight ◽

Vinyl Alcohol ◽

Poly Vinyl Alcohol ◽

Composite Hydrogels ◽

Hydrogel Composites

Herein, a series of novel, lignin-based hydrogel composites was fabricated by incorporating ultraclean lignins (UCLs), of controlled molecular weight and low dispersity, into poly(vinyl alcohol) (PVA).

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