Robust and Highly Stretchable Chitosan Nanofiber/Alumina-Coated Silica/Carboxylated Poly (Vinyl Alcohol)/Borax Composite Hydrogels Constructed by Multiple Crosslinking

We investigated the mechanical and structural properties of composite hydrogels composed of chitosan nanofiber (ChsNF), positively charged alumina-coated silica (ac-SiO2) nanoparticles, carboxylated poly (vinyl alcohol) (cPVA), and borax. ChsNF/cPVA/borax hydrogels without ac-SiO2 exhibited high Young’s modulus but poor elongation, whereas cPVA/ac-SiO2/borax hydrogels without ChsNF had moderate Young’s modulus but high elongation. ChsNF/ac-SiO2/cPVA/borax hydrogels using both ChsNF and ac-SiO2 as reinforcement agents exhibited high extensibility (930%) and high Young′s modulus beyond 1 MPa at a high ac-SiO2 concentration. The network was formed by multiple crosslinking such as the complexation between borate and cPVA, the ionic complexation between ac-SiO2 and cPVA, and the hydrogen bond between ChsNF and cPVA. Structural analysis by synchrotron small-angle X-ray scattering revealed that the nanostructural inhomogeneity in ChsNF/ac-SiO2/cPVA/borax hydrogel was suppressed compared to those of the ChsNF/cPVA/borax and cPVA/ac-SiO2/borax hydrogels.

Reviewing Chitin/Chitosan Nanofibers and Associated Nanocomposites and Their Attained Medical Milestones

Chitin/chitosan research is an expanding field with wide scope within polymer research. This topic is highly inviting as chitin/chitosan’s are natural biopolymers that can be recovered from food waste and hold high potentials for medical applications. This review gives a brief overview of the chitin/chitosan based nanomaterials, their preparation methods and their biomedical applications. Chitin nanofibers and Chitosan nanofibers have been reviewed, their fabrication methods presented and their biomedical applications summarized. The chitin/chitosan based nanocomposites have also been discussed. Chitin and chitosan nanofibers and their binary and ternary composites are represented by scattered superficial reports. Delving deep into synergistic approaches, bringing up novel chitin/chitosan nanocomposites, could help diligently deliver medical expectations. This review highlights such lacunae and further lapses in chitin related inputs towards medical applications. The grey areas and future outlook for aligning chitin/chitosan nanofiber research are outlined as research directions for the future.

CATALYTIC DETOXIFICATION OF AQUEOUS CYANIDE USING COPPER CROWN ELECTROSPUN CHITOSAN NANOFIBER

Owing to the common phenomenon of cyanide toxicity, this study focused on oxidative catalytic detoxification of aqueous cyanide in the presence of copper-crown chitosan nanofiber. To overcome the difficulty in electrospinning chitosan, chitosan-salicylaldehyde was initially synthesized via Schiff base condensation, electrospun, and post neutralised into chitosan nanofiber. The copper-crown nanofiber was prepared using the impregnation method. The nanofiber material was characterized using FT-IR, SEM, TGA and DSC. The observed pseudo first-order rate constant for the catalytic H2O2 oxidation of aqeous cyanide with copper-crown nanofiber as catalyst was found to be 16 times greater than the oxidation with only copper catalyst. In addition, the reaction was found to be dependent on the size of the copper-crown nanofiber, pH, temperature, and H2O2/CN-. The reusability of the copper-crown nanofiber catalyst makes the process economically and potentially viable for commercial application.

Antibacterial Chitosan Nanofiber Thin Films with Bacitracin Zinc Salt

Chitosan nanofiber has a highly uniform structure of 20–50 nm in diameter and shows high dispersibility in water due to its submicron size and high surface-to-volume ratio. The stacked nanofibers film is useful for breathability because it has a gap with a size of several tens of nm or more. However, the chemical bonds between the nanofibers cannot be broken during use. In this study, the thin films were obtained by filtration of chitosan nanofibers and 3-glycidoxypropyltrimethoxysilane (GPTMS) mixture. The addition of GPTMS changed the wettability, mechanical property and stability in water of the thin films. Bacitracin zinc salt (BZ) has been used for the localized dermatological medicines and loaded in the films. BZ interacted electrostatically with the thin films matrix and the release of BZ was controlled by the amount of GPTMS. A higher released amount of BZ showed higher antibacterial effects toward S. aureus. The film was also tested their toxicity by L929 fibroblasts. The release of less than 11.9 μg of BZ showed antibacterial effects, but were not toxic for fibroblast cells.