Polymorphism of fecundity genes (BMP15 and GDF9) and their association with litter size in Bangladeshi prolific Black Bengal goat

The study was undertaken to evaluate the genetic progress of Black Bengal Goat (BBG) by estimating genetic parameters viz. heritability and breeding values for economically important productive and reproductive traits (birth weight, weight at 3, 6, 9 & 12 months, daily milk yield, lactation length, total milk yield and litter size of BBG goat population). Variance and co-variance components were analyzed applying Residual Maximum Likelihood (REML) approach by VCE 4.2.5 computer package. The heritability (h2) of birth weight was estimated as 0.2, which was low. The heritability estimates for 3-month weight (0.40), 6-month weight (0.50), 9-month weight (0.37) and 12-month weight (0.36) were found medium. Estimated h2 of daily milk yield, total milk yield and lactation length in this study were from 0.55 to 0.82. h2 of litter size was 0.09. The maximum estimated breeding value (EBV) was found for 6 month body weight (12.94 kg), however, for daily milk yield, the value was 1.513 kg. The results found in this study revealed that genetic improvement of BBG for most of the traits is possible by selection and breeding. Bangladesh J. of Livestock Res. 20(1-2): 8-17, Jan-Dec 2013

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Performance and genetic parameters of economically important traits of Black Bengal goat

Journal of the Bangladesh Agricultural University ◽

10.3329/jbau.v8i1.6401 ◽

1970 ◽

Vol 8 (1) ◽

pp. 67-78 ◽

Cited By ~ 13

Author(s):

S Faruque ◽

SA Chowdhury ◽

NU Siddiquee ◽

MA Afroz

Keyword(s):

Birth Weight ◽

Litter Size ◽

First Generation ◽

Genetic Parameters ◽

Intensive Rearing ◽

Foundation Stock ◽

Daily Milk Yield ◽

Black Bengal Goat ◽

Daily Milk ◽

Intensive System

A nucleus-breeding flock of selected Black Bengal goat was established in the Bangladesh Livestock Research Institute (BLRI) with the objective of conservation and improvement of the breed. A total of 120 does of different generations (70=foundation stock, 45=First generation and 5=Second generation) and 20 bucks (15=Foundation stock and 5=First generation) were used to study the genetic parameters of Black Bengal goat on productive and reproductive traits. Animals were bred naturally. Goats were reared under intensive and semi-intensive management to compare performance. Birth weights of kids were 1.49±0.13 and 1.28±0.11 kg, respectively for intensive and semiintensive rearing system. Number of services required for each successful conception was 1.16±0.019 with an average gestation length of 143.33±0.68 days. Litter size increased (P<0.001) linearly with parity. Average litter size of Black Bengal goat was 1.94±0.06. Rearing system, season, parity, generation and generation × parity interaction did not affect (P>0.05) the post partum estrous interval. Young females attained puberty at an age and weight of 186.02±10.52 days and 9.4±0.52 kg, respectively. In case of intensive rearing system it took 139 days to show 1st heat compared to 198 days in semi-intensive rearing system. Intensive system reduced the age at 1st kidding to 284±31.2 days from 370±25.5 days in semi-intensive system. The effects of parity, generation, and generation × parity interaction on kidding interval were not significant (P>0.05). The average daily milk yield and lactation length was 1.088 kg (750g suckled milk + 338g from hand milking) and 68.07±2.83 days respectively. The effect of parity and generation on doe weight after kidding was significant (P<0.01) but the effect of generation × parity interaction was not significant (P>0.05). Heritability estimates from sire and dam component for birth weight, weight at 3, 6, 9, 12 months of age and litter size were 0.92, 0.48, 0.34, 0.45, 0.88 and 0.17, respectively. Heritability estimates only from sire component for birth weight, weight at 3, 6, 9, 12 months of age and litter size were 0.05, 0.28, 0.77, 0.29, 0.18 and 0.15, respectively. Repeatability estimates for birth weight, litter size, kidding interval and daily milk yield were 0.47, 0.15, 0.02 and 0.49, respectively. Keywords: Black Bengal goat; Performance traits; Heritability; Repeatability DOI: 10.3329/jbau.v8i1.6401J. Bangladesh Agril. Univ. 8(1): 67-78, 2010

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A comparative study on reproductive performance and productivity of the Black Bengal and Crossbred goat at Atrai, Bangladesh

University Journal of Zoology Rajshahi University ◽

10.3329/ujzru.v26i0.699 ◽

1970 ◽

Vol 26 ◽

pp. 55-57 ◽

Cited By ~ 14

Author(s):

Mohammad Mahmudul Hassan ◽

SM Niaz Mahmud ◽

SKM Azizul Islam ◽

Omar Faruk Miazi

Keyword(s):

Body Weight ◽

Weight Gain ◽

Birth Weight ◽

Litter Size ◽

Milk Yield ◽

Reproductive Performance ◽

Body Weight Gain ◽

The Other ◽

Other Hand ◽

Black Bengal Goat

The present investigation was carried out to detect the status of different productive and reproductive parameters of Black Bengal and Crossbred goats at Bandaikhara village under Atrai Upazilla of Naogaon district during the period of September to December/2005. The average age at first sign of heat of Black Bengal goats was better than that of Crossbred goats. In Black Bengal goat the average age at first kidding was 360.5±10 days, whereas, in crossbred goats it was 411.5±15.5 day. Significantly (P<0.01) lower the post partum heat period in Black Bengal goat than the crossbred goat. The average kidding interval in Black Bengal and Crossbred goats were 179±20 and 270±22 days respectively and differences are statistically significant (P<0.01). The usual numbers of kids at one time in Black Bengal goats vary from single to quadruplet. On the other hand, litter size of crossbred goat was single or twin. The average birth weight of Black Bengal goat was lower than Crossbred goats, which are statistically significant (P<0.05). The average body weight gain after 365 days is better in Crossbred than Black Bengal goats and statistically significant (P<0.01). The average milk yield in Crossbred goat was 1.05 liter/day, whereas, in Black Bengal goat, it produces milk that only nourished its kids. It was concluded that the reproductive performance like early maturity, larger litter size, shorter postpartum period, minimum kidding interval are better in Black Bengal goat. On the other hand productive performance like higher birth weight, maximum body weight gain, high milk yield, longer lactation length are suitable in crossbred goat. Key words: Black Bengal goat, Crossbred goat, Production, Reproduction, Performance Univ. j. zool. Rajshahi Univ. Vol. 26, 2007. pp. 55-57

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Genetic evaluation of production potential of Black Bengal goat using frozen semen under community based rearing system

Bangladesh Journal of Animal Science ◽

10.3329/bjas.v45i2.29811 ◽

2016 ◽

Vol 45 (2) ◽

pp. 52-59 ◽

Cited By ~ 1

Author(s):

MY Ali ◽

SS Husain ◽

SA Bhuiyan ◽

MR Islam ◽

MA Haque

Keyword(s):

Birth Weight ◽

Litter Size ◽

Average Daily Gain ◽

Genetic Correlations ◽

Production Potential ◽

Community Based ◽

Frozen Semen ◽

Body Weights ◽

Daily Milk Yield ◽

Black Bengal Goat

The objective of this study was to investigate production potential of Black Bengal goat using frozen semen under community based-rearing system. Forty Black Bengal does were distributed to the goat keepers and inseminated with frozen semen of selected Black Bengal bucks. Statistical analyses of all parameters were done using SAS. Genetic parameters were also measured using VCE software. Means along with standard errors for productive performance were 0.96±0.01, 4.25±0.06, 7.04±0.12 kg, 36.51±0.64, 31.29±0.98 g/d, and 247.80±3.13 ml/d, respectively for birth weight, body weight at 3- and 6-month, average daily gain at 3- and 6-month and daily milk yield. Reproductive performances were 1.81±0.107, 1.44±0.097, 145.33±0.649 days, 200.60±2.83 days, 7.69±1.97 kg, 40%, 19.65%, respectively for litter size, service per conception, gestation period, age and weight at first heat, conception rate and kid mortality. Effects of sex and litter size were significant (p<0.01) for birth and 3-month weight and season was significant (p<0.05) only for birth weight. Bucks showed significant effects (p<0.05) for birth and 3-month weight. Estimated heritability for birth, 3- and 6-month weight were 0.21±0.03, 0.36±0.07 and 0.12±0.05. Genetic correlations among body weights ranged from 0.35 to 0.65 and phenotypic correlations ranged from 0.44 to 0.52. Therefore, the AI program with frozen semen of Black Bengal buck would be beneficial to the farmers.Bang. J. Anim. Sci. 2016. 45 (2): 52-59

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Genetic effects of leptin receptor (LEPR) polymorphism on litter size in a Black Bengal goat population

Animal Biology ◽

10.1163/15707563-00001079 ◽

2019 ◽

Vol 69 (4) ◽

pp. 411-420 ◽

Cited By ~ 1

Author(s):

M.A. Alim ◽

M.M.K. Hossain ◽

J. Nusrat ◽

Rubaya ◽

M. Salimullah ◽

...

Keyword(s):

Litter Size ◽

Energy Homeostasis ◽

Leptin Receptor ◽

Linear Models ◽

Direct Sequencing ◽

Substitution Effects ◽

Nucleotide Polymorphisms ◽

Goat Population ◽

Exon 4 ◽

Black Bengal Goat

Abstract The leptin receptor (LEPR) is involved in central signaling for both energy homeostasis and reproduction. The present study investigates the association of the LEPR gene with the prolificacy of Black Bengal goat. Two single nucleotide polymorphisms (SNPs) in intron 3 and one SNP in exon 4 in the LEPR gene were identified by pooled DNA sequencing. The identified SNPs were genotyped by the direct sequencing method from 84 Black Bengal does. A synonymous mutation (Lysine > Lysine) was found as a polymorphism in exon 4. The effects of the different genotypes on litter size traits were estimated using linear models. Our results show that goats with heterozygous genotype AG at the loci g.104911A>G and g.105151A>G showed the highest prolificacy performance when compared with the other, homozygous genotypes. Dominance and additive effects were observed at the considered loci. No significant allele substitution effects were found for any locus. Our results indicate preliminarily that LEPR may have some association with prolificacy and could be a candidate gene to improve the prolificacy in goat.

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Polymorphism of fecundity genes (BMP15 and GDF9) and their association with litter size in Bangladeshi prolific Black Bengal goat

10.1101/2020.01.08.899443 ◽

2020 ◽

Author(s):

A. Das ◽

M. Shaha ◽

M. Das Gupta ◽

Avijit Dutta ◽

O. F. Miazi

Keyword(s):

Litter Size ◽

Nucleotide Polymorphisms ◽

Goat Breed ◽

Single Nucleotide ◽

Exon 2 ◽

Morphogenetic Protein ◽

Growth Differentiation Factor 9 ◽

Bone Morphogenetic Protein 15 ◽

First Time ◽

Black Bengal Goat

AbstractIdentification of prolificacy associated genetic markers remains vital in goat breeding industry since an increase in litter size can generate significant profit. Black Bengal is a prolific goat breed in Bangladesh. There are no inland reports on polymorphisms associated with fertility of Black Bengal goats in Bangladesh. In this study, we investigated two major fecundity genes-bone morphogenetic protein 15 (BMP15) and growth differentiation factor 9 (GDF9) in order to detect any possible mutations in these two genes in Bangladeshi Black Bengal goats. We identified six single nucleotide polymorphisms (SNP), of which five (C735A, C743A, G754T, C781A, and C808G) in BMP15 exon 2 and one (T1173A) in GDF9 exon 2. We also studied their association with litter size. Association analysis results show that polymorphism at the 735, 754 and 781 nucleotide positions of BMP15 exon 2 had significant association with litter size in Black Bengal goat. The effect of parity was also highly significant (p <0.001) on litter size. This study explored, for the first time, SNP loci in fecundity genes in Bangladeshi prolific Black Bengal goats. Further studies with a high number of genetically unrelated animals for assessing the association of these loci and others in the fecundity genes with litter size may be useful.

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Breeding and production performance profile of Black Bengal goats in rural areas of Mymensingh in Bangladesh

Bangladesh Journal of Animal Science ◽

10.3329/bjas.v45i2.29810 ◽

2016 ◽

Vol 45 (2) ◽

pp. 46-51 ◽

Cited By ~ 1

Author(s):

AFMF Islam ◽

S Nahar ◽

TSJ Tanni ◽

MA Hoque ◽

AKFH Bhuiyan

Keyword(s):

Litter Size ◽

Rural Areas ◽

Color Pattern ◽

Production Performance ◽

Average Litter Size ◽

Significant Difference ◽

And Performance ◽

Almost All ◽

Significant Distance ◽

Black Bengal Goat

The present study was conducted to know the breeding and performance profile of Black Bengal goat in 4 upazila (Mymensingh Sadar, Fulbaria, Trishal and Muktagacha) of Mymensingh district. The data were collected using a pre-tested questionnaire from 100 goat rearers. The questionnaire included primary information about goat owners, total number of goats, color pattern, birth information, fate of male kids, weight of kids, breeding system and source of breeding males, breeding cost, litter size, kid mortality, some management parameters on goat and goat rearing system under rural condition. On an average, goat per family at Mymensingh district was found to be 3.56 ±1.77 where the percentage of does and bucks were 90.61% and 9.39% respectively. Most of the farmers were found not to keep male kid for bad odor and difficult management and hence castrate them. Almost all farmers depend on natural mating to serve their does by passing a significant distance. The average service charge was found BDT 70.90±1.77, which differs significantly (P< 0.05) among four upazilas. No significant difference was found in performance of goats among four upazilas. The average body weight at 3 and 6 months of age of female goats were 4.67 ± 0.15 and 7.12±0.14 kg respectively. The average litter size was found 1.76±0.75 and the average kid mortality rate was 12.88% in Mymensingh district. From this study, it became evident that acute shortage of Black Bengal breeding bucks exists in the rural areas which may represent the overall situation of the country.Bang. J. Anim. Sci. 2016. 45 (2): 46-51

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Pituitary and ovarian response to transient doe-litter separation in nursing rabbits

Reproduction ◽

10.1530/reprod/118.2.361 ◽

2000 ◽

pp. 361-366 ◽

Cited By ~ 8

Author(s):

E Ubilla ◽

PG Rebollar ◽

D Pazo ◽

AI Esquifino ◽

JM Alvarino

Keyword(s):

Pituitary Gland ◽

Litter Size ◽

Artificial Insemination ◽

Ovarian Response ◽

Major Effect ◽

Free Access ◽

Plasma Prolactin ◽

Follicular Waves ◽

Higher Sensitivity

The effects of a transient doe-litter separation on plasma prolactin, FSH and oestradiol concentrations, as well as the effect on LH response to exogenous GnRH administered at the time of artificial insemination, were determined in nursing rabbits. The effects on fertility, and litter size after parturition, as well as litter survival after doe-litter separation, were also studied. Control does (n = 12) had free access to nursing, whereas biostimulated does (n = 12) were separated from their litters for 48 h before artificial insemination. Plasma prolactin concentrations were decreased 24 h after the doe-litter separation (P < 0.05). The response of prolactin to suckling reached 10 times the basal values measured on day 10 after parturition (P < 0.0001). Increased oestradiol concentrations were found during the 48 h after the doe-litter separation: at 0 h, before artificial insemination (P< 0. 0001), 1.0-2.0 h after artificial insemination (P < 0.001), at 2.5 h (P < 0.05), 3.0 h (P < 0.01), and at 3.5 h (P < 0.05) after artificial insemination. Exogenous GnRH administered at the time of artificial insemination caused a greater LH response in does previously separated from their litters during 48 h (P < 0.01). The transient doe-litter separation did not affect plasma FSH concentrations, fertility, litter size or litter survival. These results suggest that a transient separation of nursing does from their litters before artificial insemination results in a decrease in plasma prolactin concentrations that could promote growth of follicular waves, and high steroidogenesis activity, leading to increased oestradiol concentrations and inducing higher sensitivity of the pituitary gland to exogenous GnRH. These findings associated to the absence of suckling episodes would lead to higher LH response and, therefore, exert a major effect on fertility.

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Effects of Fetus Weight, Dam Strain, Dam Weight, and Litter Size on the Craniofacial Morphogenesis of CL/Fr Mouse Fetuses Affected with Cleft Lip and Palate

The Cleft Palate-Craniofacial Journal ◽

10.1597/1545-1569_1997_034_0325_eofwds_2.3.co_2 ◽

1997 ◽

Vol 34 (4) ◽

pp. 325-330 ◽

Cited By ~ 1

Author(s):

Kazuaki Nonaka ◽

Yasunori Sasaki ◽

Yoshihisa Watanabe ◽

Ken-ichi Yanagita ◽

Minoru Nakata

Keyword(s):

Litter Size ◽

Cleft Lip ◽

Cleft Lip And Palate ◽

Craniofacial Morphology ◽

Strain Effect ◽

Craniofacial Growth ◽

Lateral Cephalogram ◽

Mouse Fetus ◽

Mouse Fetuses ◽

Craniofacial Morphogenesis

Objective: This study examined the factors related to the morphogenesis of the craniofacial complex of the CL/Fr mouse fetus affected with CLP based on the findings of a lateral cephalogram. Design: Embryo transfer experiments were performed to determine the effect of the fetus weight, dam strain, dam weight, and litter size on the intra-uterine craniofacial morphogenesis of CL/Fr mouse fetuses. On the 18th gestational day, each pregnant dam that had received CL/Fr mouse embryos was laparotomized to remove the transferred fetuses that had developed in the uteri of the cleft lip and palate (CLP)-susceptible CL/Fr strain dam and the CLP-resistant C57BL strain dam. A cephalometric observation of the craniofacial morphology of each fetus was subsequently performed. Results: Based on a multiple regression analysis, the standardized partial regression coefficients of the affected fetus weight, the dam weight, and the litter size on the maxillary size of the affected CL/Fr fetus were 0.71 (p < .01), 0.03, and −0.07. According to a least-squares analysis of variance, the dam strain effect in addition to the effect of the affected fetus weight on the maxillary size and the cranial size of the affected fetuses was significant (p < .01 for cranial size, p < .05 for maxillary size) and close to a significant level (p = .09) for the mandibular size of the affected fetuses. The adjusted maxillary size and cranial size after statistically eliminating the effects of the affected fetus weight, dam weight, and lifter size on each original craniofacial size of the affected fetuses that had developed in the CL/Er dam strain were also significantly smaller than those of the affected fetuses that had developed in the C57BL dam strain. Conclusions: The present results indicate that the craniofacial growth of the CL/Fr mouse fetus affected with CLP increased in proportion to the fetus weight. The dam strain effect, in addition to the effect of the affected fetus weight, could thus not be ignored when the etiology of the spontaneous CLP was examined, while the uterine environment, provided by the CL/Fr strain dam, retarded the intra-uterine craniofacial growth of the affected fetuses. It was therefore concluded that the dam strain effect, as well as the effect of the affected fetus weight, both play an important role on the craniofacial morphogenesis of the CL/Fr strain of the affected fetuses that developed in both strain dams.

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