Eighty-Seven Consecutive Sleeve Gastrectomies Between the Two Peaks of the Covid-19 Pandemic. An Opening-Phase Experience

SummaryIn order to investigate the early release of NH2-terminal plasmic fragments from the Bβ chain of fibrinogen, substantial quantities of Bβ 1-42 and Bβ 1-21 are required as immunogens, as radioimmunoassay standards and for infusion into human volunteers to determine the half-lives of these peptides. Towards this end methods that employ selective proteolytic cleavage of these fragments from fibrinogen have been developed. Both the N-DSK fragment, produced by CNBr cleavage of fibrinogen, and Bβ 1-118 were employed as substrates for plasmin with the finding of higher yields from N-DSK. Bβ 1-42 and Bβ 1-21 were purified by gel filtration and ion-exchange chromatography on SP-Sephadex using volatile buffers. When the purified preparation of Bβ 1-42 was chromatographed on reverse-phase high performance liquid chromatography, two peaks of identical amino acid composition were separated, presumably due either to pyroglutamate or to amide differences.

Download Full-text

Characterization of Microcrystalline Transition from Amorphous Silicon as a Function of Hydrogen Dilution and Substrate Temperature of Hot-wire CVD

MRS Proceedings ◽

10.1557/proc-715-a17.2 ◽

2002 ◽

Vol 715 ◽

Author(s):

Keda Wang ◽

Haoyue Zhang ◽

Jian Zhang ◽

Jessica M. Owens ◽

Jennifer Weinberg-Wolf ◽

...

Keyword(s):

Substrate Temperature ◽

Sudden Change ◽

Chemical Vapor ◽

Threshold Value ◽

Ir Absorption ◽

Sudden Increase ◽

Hot Wire ◽

Hydrogen Dilution ◽

Integral Absorption ◽

Two Peaks

Abstracta-Si:H films were prepared by hot wire chemical vapor deposition. One group was deposited at a substrate temperature of Ts=250°C with varied hydrogen-dilution ratio, 0<R<10; the other group was deposited with fixed R=3 but a varied Ts from 150 to 550°C. IR, Raman and PL spectra were studied. The Raman results indicate that there is a threshold value for the microstructure transition from a- to μc-Si. The threshold is found to be R ≈ 2 at Ts = 250°C and Ts ≈ 200°C at R=3. The IR absorption of Si-H at 640 cm-1 was used to calculate the hydrogen content, CH. CH decreased monotonically when either R or Ts increased. The Si-H stretching mode contains two peaks at 2000 and 2090 cm-1. The ratio of the integral absorption peaks I2090/(I2090+I2090) showed a sudden increase at the threshold of microcrystallinity. At the same threshold, the PL features also indicate a sudden change from a- to μc-Si., i.e. the low energy PL band becomes dominant and the PL total intensity decreases. We attribute the above IR and PL changes to the contribution of microcrystallinity, especially the c-Si gain-boundaries.

Download Full-text

Opening Phase of the Third Dutch War Described by the Danish Envoy in London, March-June 1672

The Journal of Modern History ◽

10.1086/237254 ◽

1949 ◽

Vol 21 (2) ◽

pp. 97-108

Author(s):

Harold A. Hansen

Keyword(s):

The Third ◽

Opening Phase

Download Full-text

Chromosome 14 Contains Determinants That Regulate Susceptibility to Theiler's Virus–Induced Demyelination in the Mouse

Genetics ◽

10.1093/genetics/148.4.1941 ◽

1998 ◽

Vol 148 (4) ◽

pp. 1941-1949

Author(s):

J-F Bureau ◽

K M Drescher ◽

L R Pease ◽

T Vikoren ◽

M Delcroix ◽

...

Keyword(s):

Multiple Sclerosis ◽

Major Histocompatibility Complex ◽

Linkage Analysis ◽

Demyelinating Disease ◽

Theiler's Virus ◽

Chromosome 14 ◽

Virus Persistence ◽

Histocompatibility Complex ◽

Encephalomyelitis Virus ◽

Two Peaks

Abstract Theiler's murine encephalomyelitis virus causes a chronic demyelinating disease in susceptible strains of mice that is similar to human multiple sclerosis. Several nonmajor histocompatibility complex–linked genes have been implicated as determinants of susceptibility or resistance to either demyelination or virus persistence. In this study, we used linkage analysis of major histocompatibility complex identical H-2d (DBA/2J × B10.D2) F2 intercross mice to identify loci associated with susceptibility to virus-induced demyelinating disease. In a 20-cM region on chromosome 14, we identified four markers, D14Mit54, D14Mit60, D14Mit61, and D14Mit90 that are significantly associated with demyelination. Because two peaks were identified, one near D14Mit54 and one near D14Mit90, it is possible that two loci in this region are involved in controlling demyelination.

Download Full-text

Enumerative Combinatorics of Intervals in the Dyck Pattern Poset

Order ◽

10.1007/s11083-021-09552-9 ◽

2021 ◽

Author(s):

Antonio Bernini ◽

Matteo Cervetti ◽

Luca Ferrari ◽

Einar Steingrímsson

Keyword(s):

Möbius Function ◽

Dyck Path ◽

Enumerative Combinatorics ◽

Closed Expression ◽

Mobius Function ◽

First Results ◽

Two Peaks

AbstractWe initiate the study of the enumerative combinatorics of the intervals in the Dyck pattern poset. More specifically, we find some closed formulas to express the size of some specific intervals, as well as the number of their covering relations. In most of the cases, we are also able to refine our formulas by rank. We also provide the first results on the Möbius function of the Dyck pattern poset, giving for instance a closed expression for the Möbius function of initial intervals whose maximum is a Dyck path having exactly two peaks.

Download Full-text

Comparison of seasonal and longitudinal variation of daytime MSTID activity using GPS observation and GAIA simulations

Earth Planets and Space ◽

10.1186/s40623-021-01369-5 ◽

2021 ◽

Vol 73 (1) ◽

Author(s):

Mani Sivakandan ◽

Yuichi Otsuka ◽

Priyanka Ghosh ◽

Hiroyuki Shinagawa ◽

Atsuki Shinbori ◽

...

Keyword(s):

Standard Deviation ◽

Meridional Wind ◽

Lower Atmosphere ◽

Electron Content ◽

Longitudinal Variation ◽

Total Electron ◽

Winter Peak ◽

Density Perturbations ◽

Two Peaks ◽

Gps Observations

AbstractThe total electron content (TEC) data derived from the GAIA (Ground-to-topside model of Atmosphere Ionosphere for Aeronomy) is used to study the seasonal and longitudinal variation of occurrence of medium-scale traveling ionospheric disturbances (MSTIDs) during daytime (09:00–15:00 LT) for the year 2011 at eight locations in northern and southern hemispheres, and the results are compared with ground-based Global Positioning System (GPS)-TEC. To derive TEC variations caused by MSTIDs from the GAIA (GPS) data, we obtained detrended TEC by subtracting 2-h (1-h) running average from the TEC, and calculated standard deviation of the detrended TEC in 2 h (1 h). MSTID activity was defined as a ratio of the standard deviation to the averaged TEC. Both GAIA simulation and GPS observations data show that daytime MSTID activities in the northern and southern hemisphere (NH and SH) are higher in winter than in other seasons. From the GAIA simulation, the amplitude of the meridional wind variations, which could be representative of gravity waves (GWs), shows two peaks in winter and summer. The winter peak in the amplitude of the meridional wind variations coincides with the winter peak of the daytime MSTIDs, indicating that the high GW activity is responsible for the high MSTID activity. On the other hand, the MSTID activity does not increase in summer. This is because the GWs in the thermosphere propagate poleward in summer, and equatorward in winter, and the equatorward-propagating GWs cause large plasma density perturbations compared to the poleward-propagating GWs. Longitudinal variation of daytime MSTID activity in winter is seen in both hemispheres. The MSTID activity during winter in the NH is higher over Japan than USA, and the MSTID activity during winter in the SH is the highest in South America. In a nutshell, GAIA can successfully reproduce the seasonal and longitudinal variation of the daytime MSTIDs. This study confirms that GWs cause the daytime MSTIDs in GAIA and amplitude and propagation direction of the GWs control the noted seasonal variation. GW activities in the middle and lower atmosphere cause the longitudinal variation.

Download Full-text

An efficient electrochemical sensing of hazardous catechol and hydroquinone at direct green 6 decorated carbon paste electrode

Scientific Reports ◽

10.1038/s41598-021-93749-w ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

K. Chetankumar ◽

B. E. Kumara Swamy ◽

S. C. Sharma ◽

S. A. Hariprasad

Keyword(s):

Carbon Paste Electrode ◽

Limit Of Detection ◽

Tap Water ◽

Differential Pulse ◽

Electrochemical Sensing ◽

Carbon Paste ◽

Pulse Voltammetry ◽

Two Peaks ◽

Paste Electrode ◽

Scanning Electron

AbstractIn this proposed work, direct green 6 (DG6) decorated carbon paste electrode (CPE) was fabricated for the efficient simultaneous and individual sensing of catechol (CA) and hydroquinone (HY). Electrochemical deeds of the CA and HY were carried out by cyclic voltammetry (CV) and differential pulse voltammetry (DPV) at poly-DG6-modfied carbon paste electrode (Po-DG6-MCPE). Using scanning electron microscopy (SEM) studied the surface property of unmodified CPE (UCPE) and Po-DG6-MCPE. The decorated sensor displayed admirable electrocatalytic performance with fine stability, reproducibility, selectivity, low limit of detection (LLOD) for HY (0.11 μM) and CC (0.09 μM) and sensor process was originated to be adsorption-controlled phenomena. The Po-DG6-MCPE sensor exhibits well separated two peaks for HY and CA in CV and DPV analysis with potential difference of 0.098 V. Subsequently, the sensor was practically applied for the analysis in tap water and it consistent in-between for CA 93.25–100.16% and for HY 97.25–99.87% respectively.

Download Full-text

Localized surface plasmon resonance in deep ultraviolet region below 200 nm using a nanohemisphere on mirror structure

Scientific Reports ◽

10.1038/s41598-021-84550-w ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Kohei Shimanoe ◽

Soshi Endo ◽

Tetsuya Matsuyama ◽

Kenji Wada ◽

Koichi Okamoto

Keyword(s):

Surface Plasmon Resonance ◽

Surface Plasmon ◽

Plasmon Resonance ◽

Localized Surface Plasmon Resonance ◽

Localized Surface Plasmon ◽

Ultraviolet Region ◽

Simple Method ◽

Thin Film Layer ◽

Deep Ultraviolet ◽

Two Peaks

AbstractLocalized surface plasmon resonance (LSPR) was performed in the deep ultraviolet (UVC) region with Al nanohemisphere structures fabricated by means of a simple method using a combination of vapor deposition, sputtering, and thermal annealing without top-down nanofabrication technology such as electron beam lithography. The LSPR in the UV region was obtained and tuned by the initial metal film thickness, annealing temperature, and dielectric spacer layer thickness. Moreover, we achieved a flexible tuning of the LSPR in a much deeper UVC region below 200 nm using a nanohemisphere on a mirror (NHoM) structure. NHoM is a structure in which a metal nanohemisphere is formed on a metal substrate that is interposed with an Al2O3 thin film layer. In the experimental validation, Al and Ga were used for the metal hemispheres. The LSPR spectrum of the NHoM structures was split into two peaks, and the peak intensities were enhanced and sharpened. The shorter branch of the LSPR peak appeared in the UVC region below 200 nm. Both the peak intensities and linewidth were flexibly tuned by the spacer thickness. This structure can contribute to new developments in the field of deep UV plasmonics.

Download Full-text

The study of multipeaked type-I X-ray bursts in the neutron star low-mass X-ray binary 4U 1636 − 536 with RXTE

Monthly Notices of the Royal Astronomical Society ◽

10.1093/mnras/staa3539 ◽

2020 ◽

Vol 501 (1) ◽

pp. 168-178

Author(s):

Chen Li ◽

Guobao Zhang ◽

Mariano Méndez ◽

Jiancheng Wang ◽

Ming Lyu

Keyword(s):

Neutron Star ◽

Flux Ratio ◽

Light Curves ◽

Type I ◽

X Ray ◽

Soft State ◽

Peak Flux ◽

Low Mass ◽

Two Peaks ◽

Second Peak

ABSTRACT We have found and analysed 16 multipeaked type-I bursts from the neutron-star low-mass X-ray binary 4U 1636 − 53 with the Rossi X-ray Timing Explorer (RXTE). One of the bursts is a rare quadruple-peaked burst that was not previously reported. All 16 bursts show a multipeaked structure not only in the X-ray light curves but also in the bolometric light curves. Most of the multipeaked bursts appear in observations during the transition from the hard to the soft state in the colour–colour diagram. We find an anticorrelation between the second peak flux and the separation time between two peaks. We also find that in the double-peaked bursts the peak-flux ratio and the temperature of the thermal component in the pre-burst spectra are correlated. This indicates that the double-peaked structure in the light curve of the bursts may be affected by enhanced accretion rate in the disc, or increased temperature of the neutron star.

Download Full-text

Effects of Accumulated Energy on Nanoparticle Formation in Pulsed-Laser Dewetting of AgCu Thin Films

Nanoscale Research Letters ◽

10.1186/s11671-021-03564-5 ◽

2021 ◽

Vol 16 (1) ◽

Author(s):

H. K. Lin ◽

C. W. Huang ◽

Y. H. Lin ◽

W. S. Chuang ◽

J. C. Huang

Keyword(s):

Pulsed Laser ◽

Blue Shift ◽

High Energy ◽

Low Energy ◽

Nanoparticle Formation ◽

Energy Accumulation ◽

Glass Substrates ◽

Peak Absorption ◽

Two Peaks ◽

Sputtering System

AbstractAg50Cu50 films were deposited on glass substrates by a sputtering system. Effects of accumulated energy on nanoparticle formation in pulse-laser dewetting of AgCu films were investigated. The results showed that the properties of the dewetted films were found to be dependent on the magnitude of the energy accumulated in the film. For a low energy accumulation, the two distinct nanoparticles had rice-shaped/Ag60Cu40 and hemispherical/Ag80Cu20. Moreover, the absorption spectra contained two peaks at 700 nm and 500 nm, respectively. By contrast, for a high energy accumulation, the nanoparticles had a consistent composition of Ag60Cu40, a mean diameter of 100 nm and a peak absorption wavelength of 550 nm. Overall, the results suggest that a higher Ag content of the induced nanoparticles causes a blue shift of the absorption spectrum, while a smaller particle size induces a red shift.

Download Full-text