scholarly journals A hybrid system: MnO-incorporated mesoporous silica nanoparticles for theranostic applications

2018 ◽  
Vol 41 (5) ◽  
Author(s):  
Varuna Kumaravel ◽  
Kartikeyan Damodaran ◽  
Sakthivel Gandhi ◽  
Uma Maheswari Krishnan
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Hybrid System ◽  
Mesoporous Silica Nanoparticles ◽  
Theranostic Applications

Selective functionalization of mesoporous silica nanoparticles with ibuprofen and Gd(iii) chelates: a new probe for potential theranostic applications

2015 ◽  
Vol 44 (41) ◽  
pp. 17927-17931 ◽  
Author(s):  
Fabio Carniato ◽  
Mónica Muñoz-Úbeda ◽  
Lorenzo Tei ◽  
Mauro Botta
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
External Surface ◽  
Mesoporous Silica Nanoparticles ◽  
Selective Functionalization ◽  
Theranostic Applications

Organo-modified mesoporous silica nanoparticles, loaded with ibuprofen into the pores and functionalized on the external surface with a stable Gd(iii)–DOTA-monoamide chelate, were prepared and explored as potential theranostic probes.

Recent Developments in Mesoporous Silica Nanoparticles for Tumor Theranostic Applications

2021 ◽  
Vol 27 ◽  
Author(s):  
Xuerui Wang ◽  
Mengyuan Zheng ◽  
Faizal Raza ◽  
Yuhao Liu ◽  
Yiqi Wei ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Tumor Therapy ◽  
Drug Carriers ◽  
Synthetic Methods ◽  
Medicine Research ◽  
Recent Developments ◽  
Theranostic Applications ◽  
Clinical Transformation

: Due to the advantages of adjustable pore size, easy surface modification, high biocompatibility, and so on, mesoporous silica nanoparticles (MSNs) have attracted lots of attention. And they are widely used in the fields of biology and medicine research, mostly focusing on drug and gene delivery and bioimaging. This review introduces several commonly used synthetic methods of MSNs and the latest progress of MSNs in tumor therapy and diagnosis, mainly including the study about modified MSNs as drug carriers and the application of MSNs in bioimaging. The deficiencies of MSNs’ application and prospects for its future clinical transformation are also discussed.

Polymeric Nanogels for Theranostic Applications: A Mini-Review

2020 ◽  
Vol 16 (3) ◽  
pp. 392-398 ◽  
Author(s):  
Vineeth M. Vijayan ◽  
Pradipika Natamai Vasudevan ◽  
Vinoy Thomas
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Metallic Nanoparticles ◽  
Functional Performance ◽  
Mesoporous Silica Nanoparticles ◽  
Review Article ◽  
Present Review ◽  
Theranostic Agents ◽  
Theranostic Applications ◽  
State Of Art

Theranostics is a recently emerging area in nanomedicine. Nanoparticles which can combine both diagnostic and therapy in one single platform serve as theranostic agents. Some of the currently explored nanoparticles are metallic nanoparticles, mesoporous silica nanoparticles, carbonbased nanoparticles, and polymer nanogels. Polymeric nanogels are receiving considerable attention due to their high biocompatibility and functional performance. The present review article briefly summarizes the scopes and challenges of the state of art of using polymeric nanogels for theranostic applications. Among the different polymer nanogels, a special emphasis is given to polymeric nanogels with innate imaging potential.

Large pore mesoporous silica nanomaterials for application in delivery of biomolecules

Nanoscale ◽  
2015 ◽  
Vol 7 (6) ◽  
pp. 2199-2209 ◽  
Author(s):  
Nikola Ž. Knežević ◽  
Jean-Olivier Durand
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Intracellular Delivery ◽  
Core Shell ◽  
Silica Nanomaterials ◽  
Large Pore ◽  
Theranostic Applications

Large pore-mesoporous silica nanoparticles and their core/shell magnetic analogues are capable of loading and intracellular delivery of various biomolecules for theranostic applications.

Theranostic applications of mesoporous silica nanoparticles and their organic/inorganic hybrids

2013 ◽  
Vol 1 (25) ◽  
pp. 3128 ◽  
Author(s):  
Nai-Tzu Chen ◽  
Shih-Hsun Cheng ◽  
Jeffrey S. Souris ◽  
Chin-Tu Chen ◽  
Chung-Yuan Mou ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Theranostic Applications

Advances in the Use of Multifunctional Mesoporous Silica Nanoparticles and Related Nanomaterials as Carriers for the Cancer Treatment

2018 ◽  
Vol 19 (2) ◽  
pp. 131-141 ◽  
Author(s):  
Chunyu Song ◽  
Xinghua Wang ◽  
Yujun Wang ◽  
Hongbo Yu ◽  
Yali Cui ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Cancer Treatment ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles

Recent Advances in Application of Azobenzenes Grafted on Mesoporous Silica Nanoparticles in Controlled Drug Delivery Systems Using Light as External Stimulus

2020 ◽  
Vol 20 (11) ◽  
pp. 1001-1016
Author(s):  
Sandra Ramírez-Rave ◽  
María Josefa Bernad-Bernad ◽  
Jesús Gracia-Mora ◽  
Anatoly K. Yatsimirsky
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Drug Delivery Systems ◽  
Mesoporous Silica Nanoparticles ◽  
High Surface ◽  
Delivery Systems ◽  
Surface Reactivity ◽  
External Stimulus ◽  
Recent Advances

Hybrid materials based on Mesoporous Silica Nanoparticles (MSN) have attracted plentiful attention due to the versatility of their chemistry, and the field of Drug Delivery Systems (DDS) is not an exception. MSN present desirable biocompatibility, high surface area values, and a well-studied surface reactivity for tailoring a vast diversity of chemical moieties. Particularly important for DDS applications is the use of external stimuli for drug release. In this context, light is an exceptional alternative due to its high degree of spatiotemporal precision and non-invasive character, and a large number of promising DDS based on photoswitchable properties of azobenzenes have been recently reported. This review covers the recent advances in design of DDS using light as an external stimulus mostly based on literature published within last years with an emphasis on usually overlooked underlying chemistry, photophysical properties, and supramolecular complexation of azobenzenes.

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