Efficacy of Zingiber officinale and Cinnamomum zeylanicum extracts against experimental Trichinella spiralis infection

2021 ◽  
Author(s):  
Marwa Ahmed Mohamed Salama ◽  
Nahed E. Mostafa ◽  
Naglaa Fathy Abd El-Aal ◽  
Howayda Said Fouad Moawad ◽  
Samar Kamel Hammad ◽  
...  
Keyword(s):  
Trichinella Spiralis ◽  
Zingiber Officinale ◽  
Cinnamomum Zeylanicum

scholarly journals The Curative Effect of Zingiber Officinale and Cinnamomum Zeylanicum Extracts on Experimental Trichinella Spiralis Infection

2021 ◽  
Author(s):  
Marwa Ahmed Mohamed Salama ◽  
Nahed Elsayed Mostafa ◽  
Naglaa Fathy Abd El-Aal ◽  
Howayda S. F. Moawad ◽  
Samar Kamel Hammad ◽  
...  
Keyword(s):  
Trichinella Spiralis ◽  
Zingiber Officinale ◽  
Treated Group ◽  
Health Concern ◽  
Therapeutic Effects ◽  
Cinnamomum Zeylanicum ◽  
Infected Control ◽  
Transmission Electron ◽  
Tnf Α ◽  
Α Level

Abstract Trichinellosis is a re-emerging zoonotic disease that has become a public health concern since its reported human outbreaks in many countries. The traditional therapy has many adverse effects in addition to the developing resistance. So, this necessitates finding effective natural alternatives. The current study targeted to assess the potential therapeutic effects of Zingiber officinale and Cinnamomum zeylanicum in comparison to albendazole, a conventional therapy for treatment of trichinosis. Sixty mice were classified into five groups (12 mice each), non-infected control, infected control, combined albendazole and prednisolone, Zingiber officinale, and Cinnamomum zeylanicum treated groups. Mice sacrifice was performed on the 7th and 35th days post infection for intestinal and muscular phases respectively. Efficiency of the used preparations was assessed by parasitological, histopathological, immunohistochemical, biochemical studies in addition to ultrastructural evaluation using transmission electron microscopy. A significant reduction in the mean number of T. spiralis adults and larvae was observed in Zingiber officinale and Cinnamomum zeylanicum treated groups, (64.5%, 50.8%) and (68%, 54.6%) respectively. Also, both extracts showed moderate cytoplasmic reactivity for TGF-β1, (69.3% & 67.8%) respectively. The highest reduction in serum TNF- α level was observed in Zingiber officinale treated group during the muscle phase (58.4%) while in the intestinal phase was 50%. The ultrastructural study revealed degenerative effects on both adults and larvae in addition to obvious improvement of the histopathological changes in the small intestine and muscles. We concluded that these herbal extracts especially Zingiber officinale can be considered a practical and successful alternative for the treatment of trichinellosis.

Antifungal and antimycotoxigenic effects of Zingiber officinale, Cinnamomum zeylanicum and Cymbopogon martinii essential oils against Fusarium verticillioides

2020 ◽  
pp. 1-11
Author(s):  
Juliana Cristina Castro ◽  
Giseli Cristina Pante ◽  
Bruno Martins Centenaro ◽  
Rafaela Takako Ribeiro De Almeida ◽  
Eduardo Jorge Pilau ◽  
...  
Keyword(s):  
Essential Oils ◽  
Fusarium Verticillioides ◽  
Zingiber Officinale ◽  
Cinnamomum Zeylanicum ◽  
Cymbopogon Martinii

scholarly journals Inhibition activity of Zingiber offcinale. and Cinnamomum zeylanicum extract against Aspergillus niger and Penicillium notatum

2018 ◽  
Vol 11 (1) ◽  
pp. 15-20
Author(s):  
E Muslim ◽  
A Saeed ◽  
SH Sabeeh
Keyword(s):  
Antifungal Activity ◽  
Aspergillus Niger ◽  
Fungal Pathogens ◽  
Zingiber Officinale ◽  
Inhibition Activity ◽  
Cinnamomum Zeylanicum ◽  
Penicillium Notatum ◽  
Study Results ◽  
Significant Difference ◽  
Ethanolic Extracts

Aqueous and ethanolic extracts of ginger )Zingier officinale) and (Cinnamomum zeylanicum) were used to investigate an antifungal activity against food spoilage fungal pathogens. Study of the inhibitory effect of these extract was done separately against Aspergillus niger and Penicillium notatum isolated from (tomato pasts, cheese) the samples were cultured on Sabouraud's dextrose agar (SDA) at pH 5.6 and 28°C. In this study, results had shown that the extracts of Both plant demonstrated antifungal activity. When compare extracts of the two plants, C. zeylanicum extracts showed higher inhibition activity than (Zingiber officinale) extracts significantly. Ethanolic extracts of these tow plants gives significantly inhabitation in the mycelia growth of fungi more than their aqueous extracts (16-22), (19-25)mm, P. noitatum and A. niger respectively while the inhibitory observed by the aqueous extract (5-6) mm against A. niger for (6-8) mm. Against P. notatum was the most affected by all extracts while A. niger was the least susceptible. There was a significant difference (P=0.05) between groups in the antifungal activities of tested fungi, and the effectiveness of ethanolic extracts was increased with increase in their concentrations. The ability of these extracts to inhibit the growth of the two fungi must take into consideration an indication of the antifungal potency of cinnamon and Zingiber officinale, that makes them the candidate for the production of antifungal agents.

scholarly journals Atividade antimicrobiana de óleos essenciais de condimentos frente a amostras de Escherichia coli isoladas de aves e bovinos

2011 ◽  
Vol 41 (6) ◽  
pp. 1051-1056 ◽  
Author(s):  
Deise Flores Santurio ◽  
Mateus Matiuzzi da Costa ◽  
Grazieli Maboni ◽  
Carlos Pasqualin Cavalheiro ◽  
Mariangela Facco de Sá ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Zingiber Officinale ◽  
Ocimum Basilicum ◽  
Rosmarinus Officinalis ◽  
Salvia Officinalis ◽  
Thymus Vulgaris ◽  
Origanum Vulgare ◽  
Cinnamomum Zeylanicum

A discutida questão da substituição do uso de antibacterianos em rações (promotores de crescimento) requer urgentes alternativas. Face às necessidades de inibidores microbianos nesses alimentos, os óleos essenciais (OES) se constituem em alternativa, sob avaliação. Neste estudo, avaliou-se a atividade antimicrobiana dos OES de Origanum vulgare (orégano), Thymus vulgaris (tomilho), Cinnamomum zeylanicum (canela), Lippia graveolens (orégano mexicano), Zingiber officinale (gengibre), Salvia officinalis (sálvia), Rosmarinus officinalis (alecrim) e Ocimum basilicum (manjericão) frente a amostras de Escherichia coli isoladas de fezes de aves (n=43) e de bovinos (n=36). A concentração inibitória mínima (CIM) e a concentração bactericida mínima (CBM) foram determinadas para cada isolado através da técnica de microdiluição em caldo, a partir da máxima concentração de 6400µg mL-1 de cada OE testado. Observou-se atividade antimicrobiana para os OES de orégano, orégano mexicano, tomilho, canela. Para todas as amostras testadas, independente de sua origem, os OES mais e menos efetivos quanto à atividade antimicrobiana foram o orégano e a canela, respectivamente. Esses resultados confirmaram o potencial antibacteriano de alguns OES, os quais merecem novas investigações abordando sua adição na alimentação de aves e bovinos.

scholarly journals Surveying the chemical composition and antibacterial activity of essential oils from selected medicinal plants against human pathogens

2020 ◽  
Author(s):  
Mahmoud Osanloo ◽  
Ghazal Ghaznavi ◽  
Abbas Abdollahi
Keyword(s):  
Essential Oils ◽  
Biological Activities ◽  
Antibacterial Properties ◽  
Zingiber Officinale ◽  
New Drugs ◽  
Citrus Limon ◽  
Human Pathogens ◽  
Anethum Graveolens ◽  
Cinnamomum Zeylanicum ◽  
Artemisia Dracunculus

Background and Objectives: Essential oils (EOs) with different biological activities, such as antibacterial properties, are a valuable resource for developing new drugs. Materials and Methods: Ingredients of six medicinally important EOs, including Artemisia dracunculus, Anethum graveolens, Citrus limon, Citrus sinensis, Cinnamomum zeylanicum and Zingiber officinale, were identified using GC-MS analysis. Moreover, their five major compounds were also listed. Furthermore, the half-maximal inhibitory concentration (IC50) against four important human bacteria was also investigated using the 96-well plate microdilution. Results: C. sinensis EO with IC50 of 1.0 and 4.7 mg.mL-1 have the most effect on the growth of S. aureus and P. aeruginosa. Moreover, EOs of Cinnamomum zeylanicum (IC50: 1.0 mg. mL-1) and Artemisia dracunculus (IC50: 1.3 mg.mL-1) significantly showed better inhibitory effect on E. coli and K. pneumoniae. Conclusion: These EOs could be used for developing inexpensive, potent, and green antibacterial agents.

scholarly journals التحري عن وجود بعض المعادن الثقيلة والميكروبات في التوابل

2021 ◽  
Vol 3 (3) ◽  
pp. 41-48
Author(s):  
وفاء معاد محمد ◽  
رافد خليل عبد الرزاق
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Nigella Sativa ◽  
Zingiber Officinale ◽  
World Health ◽  
Piper Nigrum ◽  
Cinnamomum Zeylanicum ◽  
Food And Agriculture ◽  
Food And Agriculture Organization ◽  
Health Organization

تضمنت الدراسة جمع 11 نوعاَ من التوابل التي تباع في الاسواق المحلية لمدينة تكريت (الكزبرة Coriandrum sativum L,والكاري، والكركمCurcuma Longa, والزنجبيل Zingiber officinale, والفلفل الاسود Piper nigrum, وبهارات الطرشي, وبهارات البرياني, وحبة البركة  Nigella sativa, والقرفة cinnamomum zeylanicum, والسماق  R. coriaria L, والكمون Cuminum Cyminum) للتحري عن وجود بعض أنواع العناصر الثقيلة وتشخيص الأحياء المجهرية الملوثة لها . اظهرت النتائج أن تركيز بعض العناصر الثقيلة ضمن الحدود المسموح بها وفق المواصفة القياسية التي وضعتها World Health Organization (WHO) و Food and Agriculture Organization ((FAOالى خلو التوابل من العنصرين الكادميوم والرصاص في حين وجد الزنك والنيكل والكوبلت بتراكيز مختلفة في الانواع المختلفة الاخرى من التوابل. وكان تركيز النيكل اعلى من الحد المسموح في عينات الفلفل الاسود والدارسين (القرفة) والكركم حيث بلغ (4.959, 3.850, 2.740) ppm على التوالي في حين كان تركيز النيكل في باقي العينات اقل من 0.05 ppm وهي اقل من الحد المسموح به, وكذلك كان تركيز الكوبلت اعلى من الحد المسموح  في عينات الفلفل الاسود والكاري حيث بلغت (4.930 و3.732ppm ( على التوالي اما باقي العينات من التوابل فكان اقل من الحد المسموح به .في حين وجد ان محتوى عينات التوابل من الزنك في جميع عينات التوابل هو تحت الحد المسموح به (100) pmm حسب ((FAO و( WHO) تراوحت القيم بين ppm 0.392 –1.794 ppm , بلغ العدد الكلي البكتيري في التوابل بين (5 ×510 ) و ( 95× 510) وحدة تكوين المستعمرة/غم في حين لوحظ وجود Escherichia coli في النماذج المفحوصة بأجمعها بأعداد تراوحت بين (93×510 _ 35× 510) وحدة تكوين المستعمرة/غم في حين تراوح عدد بكتيريا Staphylococcus  aureus ) 1×510  الى 17 ×10 5 ) وحدة تكوين المستعمرة/غم , مع ملاحظة ظهور الخمائر والاعفان في كل من الكزبرة، الزنجبيل, وبهارات برياني والدارسين (القرفة) وبهارات الطرشي والكمون والفلفل الأسود والكاري والكركم وبأعداد بلغت ( 12×105 ,10×105, 12×105, 6×105, 14×105, 5×105, 2×105, 7×105 و6×510) وحدة تكوين المستعمرة/غم على التوالي.    في حين وجد ان محتوى عينات التوابل من الزنك في جميع عينات التوابل هو تحت الحد المسموح به (100) pmm حسب ((FAO و ( WHO) وكانت القيم بين ppm 0.392 –1.794 ppm .و بلغ العدد الكلي البكتيري في التوابل بين (5 ×510 ) و ( 95× 510  ) و.ت.م./غم في حين لوحظ تواجد E.coli في النماذج المفحوصة بأجمعها بأعداد تراوحت بين (  93×510 _ 35× 510) و.ت.م/غم في حين تراوح عدد بكتيريا ) Staphylococcus aureus, 1×510  الى 17 ×10 5 ) و.ت.م/غم .

scholarly journals Óleos essenciais no tratamento de sementes de Phaseolus vulgaris L. durante o armazenamento

2018 ◽  
Vol 13 (2) ◽  
pp. 186
Author(s):  
Keidima Leite ◽  
Lisandro Tomas da Silva Bonome ◽  
Gabriela Silva Moura ◽  
Gilmar Franzener
Keyword(s):  
Phaseolus Vulgaris ◽  
Citrus Sinensis ◽  
Zingiber Officinale ◽  
Mentha Piperita ◽  
Melissa Officinalis ◽  
Cymbopogon Citratus ◽  
Phaseolus Vulgaris L ◽  
Cinnamomum Zeylanicum ◽  
Citrus Aurantifolia ◽  
Penicillium Spp

Os óleos essenciais apresentam metabólitos secundários com propriedades antibacteriana e antifúngica. Nesse sentido, objetivou-se com esse trabalho avaliar a incidência de fitopatógenos e a qualidade fisiológica de sementes de Phaseolus vulgaris L. cv. BRS Esplendor, tratadas com diferentes óleos essenciais em diferentes embalagens e tempos de armazenamento. Foram avaliados os óleos essenciais de canela (Cinnamomum zeylanicum), capim-limão (Cymbopogon citratus), cravo da índia (Syzgium aromaticum), erva-cidreira (Melissa officinalis), gengibre (Zingiber officinale), laranja-doce (Citrus sinensis), hortelã-pimenta (Mentha piperita.) e limão-taiti (Citrus aurantifolia), fungicida comercial e a testemunha, embalados em kraft ou pet. Aos 0, 60, 120 e 180 dias após o armazenamento das sementes, avaliou-se o teor de água; primeira contagem da germinação; porcentagem de germinação; índice de velocidade de emergência (IVE), emergência de plântulas, matéria seca e blotter test. Aos 120 e 180 dias após o armazenamento os tratamentos com óleos essenciais de C. aurantifolia e C. zeylanicum não afetaram a porcentagem de germinação das sementes quando acondicionadas em embalagem kraft. Entre as embalagens houve diferença significativa quando as sementes foram tratadas com os óleos essenciais de C. zeylanicum; C.sinensis e M. officinalis que reduziram a incidência do fungo do gênero Aspergillus spp. Os óleos essenciais de C. zeylanicum e S. aromaticum diminuíram a incidência de Penicillium spp., ambos armazenados em pet, tendo o óleo essencial de C. zeylanicum o comportamento semelhante ao fungicida comercial. A embalagem kraft foi mais eficiente em preservar a qualidade fisiológica das sementes tratadas de Phaseolus vulgaris L. do que a embalagem pet. No tempo zero de armazenamento, os tratamentos com C. sinensis e S. aromaticum promoveram efeito negativo sobre a qualidade fisiológica das sementes comparado a testemunha. O óleo essencial de C. citratus influenciou negativamente na porcentagem de germinação das sementes em relação aos demais óleos essenciais quando armazenado em saco kraft.

scholarly journals Óleos essenciais de Cymbopogon nardus, Cinnamomum zeylanicum e Zingiber officinale: composição, atividades antioxidante e antibacteriana

2012 ◽  
Vol 43 (2) ◽  
pp. 399-408 ◽  
Author(s):  
Milene Aparecida Andrade ◽  
Maria das Graças Cardoso ◽  
Luís Roberto Batista ◽  
Aline Cristina Teixeira Mallet ◽  
Samísia Maria Fernandes Machado
Keyword(s):  
Zingiber Officinale ◽  
Cinnamomum Zeylanicum ◽  
Cymbopogon Nardus
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