Evidence Map of Mindfulness for Stages of Psychosis: State of the Literature and Implications for Future Research

Mindfulness ◽  
2021 ◽  
Author(s):  
Daniel Reich ◽  
Subhadra Evans ◽  
Barnaby Nelson ◽  
Tara Hickey ◽  
Melissa O’Shea
Keyword(s):  
Future Research ◽  
Evidence Map

Research into Australian emergency services personnel mental health and wellbeing: An evidence map

2017 ◽  
Vol 52 (2) ◽  
pp. 129-148 ◽  
Author(s):  
Tracey Varker ◽  
Olivia Metcalf ◽  
David Forbes ◽  
Katherine Chisolm ◽  
Sam Harvey ◽  
...  
Keyword(s):  
Mental Health ◽  
Emergency Services ◽  
Mental Health Problems ◽  
Cochrane Library ◽  
National Study ◽  
Future Research ◽  
Primary Research ◽  
Evidence Map ◽  
Health And Wellbeing ◽  
Emergency Services Personnel

Background: Evidence maps are a method of systematically characterising the range of research activity in broad topic areas and are a tool for guiding research priorities. Aims: ‘Evidence-mapping’ methodology was used to quantify the nature and distribution of recent peer-reviewed research into the mental health and wellbeing of Australian emergency services personnel. Methods: A search of the PsycINFO, EMBASE and Cochrane Library databases was performed for primary research articles that were published between January 2011 and July 2016. Results: In all, 43 studies of primary research were identified and mapped. The majority of the research focused on organisational and individual/social factors and how they relate to mental health problems/wellbeing. There were several areas of research where very few studies were detected through the mapping process, including suicide, personality, stigma and pre-employment factors that may contribute to mental health outcomes and the use of e-health. No studies were detected which examined the prevalence of self-harm and/or harm to others, bullying, alcohol/substance use, barriers to care or experience of families of emergency services personnel. In addition, there was no comprehensive national study that had investigated all sectors of emergency services personnel. Conclusion: This evidence map highlights the need for future research to address the current gaps in mental health and wellbeing research among Australian emergency services personnel. Improved understanding of the mental health and wellbeing of emergency services personnel, and the factors that contribute, should guide organisations’ wellbeing policies and procedures.

scholarly journals Evidence map of pancreatic surgery: protocol for a living systematic review and meta-analysis

BMJ Open ◽  
2019 ◽  
Vol 9 (9) ◽  
pp. e032353
Author(s):  
Pascal Probst ◽  
Felix J Hüttner ◽  
Ömer Meydan ◽  
Eva Kalkum ◽  
Rüdiger Kretschmer ◽  
...  
Keyword(s):  
Pancreatic Surgery ◽  
Clinical Decision Making ◽  
Meta Analysis ◽  
Clinical Decision ◽  
Outcome Data ◽  
Primary Data ◽  
Future Research ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
Evidence Map

IntroductionPancreatic surgery is a large and complex field of research. Several evidence gaps exist for specific diseases or surgical procedures. An overview on existing knowledge is needed to plan and prioritise future research. The aim of this project is to create a systematic and living evidence map of pancreatic surgery.Methods and analysisA systematic literature search in MEDLINE (via PubMed), Web of Science and Cochrane Central Register of Controlled Trials will be performed searching for all randomised controlled trials (RCT) and systematic reviews (SR) on pancreatic surgery. RCT and SR will be grouped in research topics. Baseline and outcome data from RCT will be extracted, presented and effect sizes meta-analysed. Data from SR will be used to identify evidence gaps. A freely accessible web-based evidence map in the format of a mind map will be created. The evidence map and meta-analyses will be updated periodically.DisseminationAfter completion of the project, a permanently updated evidence map of pancreatic surgery will be available to patients, physicians, researchers and funding bodies viawww.evidencemap.surgery. Its use will allow clinical decision-making based on primary data and prioritisation of future research endeavours.PROSPERO registration numberCRD42019133444.

scholarly journals Coronavirus Disease 2019 (COVID-19): An Evidence Map of Medical Literature

2020 ◽  
Author(s):  
Nan Liu ◽  
Marcel Lucas Chee ◽  
Chenglin Niu ◽  
Pin Pin Pek ◽  
Fahad Javaid Siddiqui ◽  
...  
Keyword(s):  
Indirect Effects ◽  
Research Collaboration ◽  
Medical Literature ◽  
Mental Health Research ◽  
Future Research ◽  
International Level ◽  
Evidence Map ◽  
Artificial Intelligence Research ◽  
Substantial Body ◽  
Novel Technologies

AbstractSince the beginning of the COVID-19 outbreak in December 2019, a substantial body of COVID-19 medical literature has been generated. As of May 2020, gaps in the existing literature remain unidentified and, hence, unaddressed. In this paper, we summarise the medical literature on COVID-19 between 1 January and 24 March 2020 using evidence maps and bibliometric analysis in order to systematically identify gaps and propose areas for valuable future research. The examined COVID-19 medical literature originated primarily from Asia and focussed mainly on clinical features and diagnosis of the disease. Many areas of potential research remain underexplored, such as mental health research, the use of novel technologies and artificial intelligence, research on the pathophysiology of COVID-19 within different body systems, and research on indirect effects of COVID-19 on the care of non-COVID-19 patients. Research collaboration at the international level was limited although improvements may aid global containment efforts.

Co-production scoping review: protocol  v1

2021 ◽  
Author(s):  
Helen J J. Smith ◽  
Luke Budworth ◽  
Chloe Grindey ◽  
Isabel Hague ◽  
Natalie Hamer ◽  
...  
Keyword(s):  
Scoping Review ◽  
Health Research ◽  
Healthcare Services ◽  
Future Research ◽  
Evidence Map ◽  
Methodological Research ◽  
Production Practice ◽  
Review Protocol ◽  
The Uk ◽  
Applied Health Research

Background Interest in and use of co-production in healthcare services and research is growing. Previous reviews have summarised co-production approaches in use, collated outcomes and effects of co-production and focused on replicability and reporting, but none have critically reflected on how co-production in applied health research might be evolving and the implications of this for future research. We aim to conduct a scoping review to systematically map recent literature on co-production in applied health research in the UK to inform co-production practice and guide future methodological research. Methods Scoping review using established methods. We will created an evidence map to show the extent and nature of the literature on co-production and applied health research, based on this we described the characteristics of the articles and scope of the literature and summarised conceptualisations of co-production and how it was implemented. We will extract implications for co-production practice or future research and conduct a content analysis of this information to identify lessons for the practice of co-production and themes for future methodological research. Results We will report on lessons for the practice of co-production and themes for future research on co-production.

scholarly journals Evidence Map of Prevention and Treatment Interventions for Depression in Young People

2012 ◽  
Vol 2012 ◽  
pp. 1-11 ◽  
Author(s):  
Patrick Callahan ◽  
Ping Liu ◽  
Rosemary Purcell ◽  
Alexandra G. Parker ◽  
Sarah E. Hetrick
Keyword(s):  
Young People ◽  
Future Research ◽  
Optimal Care ◽  
Evidence Map ◽  
High Quality Research ◽  
Evidence Mapping ◽  
Prevention And Treatment ◽  
Evidence Based Treatments ◽  
Problematic Substance ◽  
Ssri Medication

Introduction.Depression in adolescents and young people is associated with reduced social, occupational, and interpersonal functioning, increases in suicide and self-harm behaviours, and problematic substance use. Age-appropriate, evidence-based treatments are required to provide optimal care.Methods.“Evidence mapping” methodology was used to quantify the nature and distribution of the extant high-quality research into the prevention and treatment of depression in young people across psychological, medical, and other treatment domains.Results.Prevention research is dominated by cognitive-behavioral- (CBT-) based interventions. Treatment studies predominantly consist of CBT and SSRI medication trials, with few trials of other psychological interventions or complementary/alternative treatments. Quality studies on relapse prevention and treatment for persistent depression are distinctly lacking.Conclusions.This map demonstrates opportunities for future research to address the numerous evidence gaps for interventions to prevent or treat depression in young people, which are of interest to clinical researchers, policy makers, and funding bodies.

scholarly journals Travel-related control measures to contain the COVID-19 pandemic: an evidence map

BMJ Open ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. e041619
Author(s):  
Ani Movsisyan ◽  
Jacob Burns ◽  
Renke Biallas ◽  
Michaela Coenen ◽  
Karin Geffert ◽  
...  
Keyword(s):  
Infectious Disease ◽  
Middle East ◽  
Evidence Synthesis ◽  
Middle East Respiratory Syndrome ◽  
Control Measures ◽  
Social Outcomes ◽  
Future Research ◽  
Human Populations ◽  
Evidence Map ◽  
The Impact

ObjectivesTo comprehensively map the existing evidence assessing the impact of travel-related control measures for containment of the SARS-CoV-2/COVID-19 pandemic.DesignRapid evidence map.Data sourcesMEDLINE, Embase and Web of Science, and COVID-19 specific databases offered by the US Centers for Disease Control and Prevention and the WHO.Eligibility criteriaWe included studies in human populations susceptible to SARS-CoV-2/COVID-19, SARS-CoV-1/severe acute respiratory syndrome, Middle East respiratory syndrome coronavirus/Middle East respiratory syndrome or influenza. Interventions of interest were travel-related control measures affecting travel across national or subnational borders. Outcomes of interest included infectious disease, screening, other health, economic and social outcomes. We considered all empirical studies that quantitatively evaluate impact available in Armenian, English, French, German, Italian and Russian based on the team’s language capacities.Data extraction and synthesisWe extracted data from included studies in a standardised manner and mapped them to a priori and (one) post hoc defined categories.ResultsWe included 122 studies assessing travel-related control measures. These studies were undertaken across the globe, most in the Western Pacific region (n=71). A large proportion of studies focused on COVID-19 (n=59), but a number of studies also examined SARS, MERS and influenza. We identified studies on border closures (n=3), entry/exit screening (n=31), travel-related quarantine (n=6), travel bans (n=8) and travel restrictions (n=25). Many addressed a bundle of travel-related control measures (n=49). Most studies assessed infectious disease (n=98) and/or screening-related (n=25) outcomes; we found only limited evidence on economic and social outcomes. Studies applied numerous methods, both inferential and descriptive in nature, ranging from simple observational methods to complex modelling techniques.ConclusionsWe identified a heterogeneous and complex evidence base on travel-related control measures. While this map is not sufficient to assess the effectiveness of different measures, it outlines aspects regarding interventions and outcomes, as well as study methodology and reporting that could inform future research and evidence synthesis.

scholarly journals Profiling Research on PFAS in Wildlife: Protocol of a Systematic Evidence Map and Bibliometric Analysis

2021 ◽  
Author(s):  
Catharina Vendl ◽  
Matthew Taylor1 ◽  
Jennifer Braeunig ◽  
Matthew Gibson ◽  
Daniel Hesselson ◽  
...  
Keyword(s):  
Bibliometric Analysis ◽  
Anthropogenic Impacts ◽  
Grey Literature ◽  
Future Research ◽  
Systematic Map ◽  
Comprehensive Overview ◽  
Evidence Map ◽  
Wildlife Species ◽  
Commercial Applications ◽  
Abundance And Distribution

Abstract Background: Per- and polyfluoroalkyl substances (PFAS) are a large group of manufactured chemicals. Since the beginning of their commercial manufacturing in the 1950s, PFAS haven’t only found their way into numerous industrial and commercial applications, but also into the bloodstream of the majority of the human population, the natural environment and its wildlife. Exposure to high levels of PFAS can create health risks for humans and animals which may exacerbate the effects of other anthropogenic impacts faced by wildlife species. To gain a comprehensive overview of the abundance and distribution of PFAS in wildlife species, and to better understand the risk of PFAS exposure on threatened species and PFAS transfer into human food chains, we will collate the available literature into a systematic evidence map and bibliometric analysis.Methods: We will conduct a comprehensive systematic literature search on Scopus, Web of Science and the ‘grey literature’. For screening purposes, we will use decision trees, scanning title, abstract and keywords first. The next step includes full-text screening performed by two reviewers. We will only consider publications in English, peer-reviewed articles, pre-prints and theses. We will limit our search to 31 PFAS types (based on a previous study). A pilot search on Scopus resulted in ~250 potentially relevant publications. We will scan all publications included in the systematic map for predetermined indicators of quality and potential study-level biases. In addition, we will extract bibliometric records from Scopus and perform network analysis. We will present the results using a narrative summary, tables (database), bar plots and colour-coded maps. Results will be available on a dedicated freely accessible website. Discussion: This study will provide critical insight into the gaps and clusters of the literature with regards to the PFAS concentration in wildlife. Therefore, our study will inform and direct future research efforts to fill the gaps revealed.Systematic review registration: osf.io osf.io/gnt2y

Parasite defense mechanisms in bees: behavior, immunity, antimicrobials, and symbionts

2019 ◽  
Vol 4 (1) ◽  
pp. 59-76 ◽  
Author(s):  
Alison E. Fowler ◽  
Rebecca E. Irwin ◽  
Lynn S. Adler
Keyword(s):  
Defense Mechanisms ◽  
Poor Quality ◽  
Future Research ◽  
Immune Priming ◽  
Social Bees ◽  
Bee Health ◽  
Landscape Scales ◽  
And Function ◽  
Solitary Species

Parasites are linked to the decline of some bee populations; thus, understanding defense mechanisms has important implications for bee health. Recent advances have improved our understanding of factors mediating bee health ranging from molecular to landscape scales, but often as disparate literatures. Here, we bring together these fields and summarize our current understanding of bee defense mechanisms including immunity, immunization, and transgenerational immune priming in social and solitary species. Additionally, the characterization of microbial diversity and function in some bee taxa has shed light on the importance of microbes for bee health, but we lack information that links microbial communities to parasite infection in most bee species. Studies are beginning to identify how bee defense mechanisms are affected by stressors such as poor-quality diets and pesticides, but further research on this topic is needed. We discuss how integrating research on host traits, microbial partners, and nutrition, as well as improving our knowledge base on wild and semi-social bees, will help inform future research, conservation efforts, and management.

Dicarbonyl derived post-translational modifications: chemistry bridging biology and aging-related disease

2020 ◽  
Vol 64 (1) ◽  
pp. 97-110
Author(s):  
Christian Sibbersen ◽  
Mogens Johannsen
Keyword(s):  
Mass Spectrometry ◽  
Future Research ◽  
Amino Acid Residues ◽  
Post Translational Modification ◽  
Dicarbonyl Compounds ◽  
Protein Targets ◽  
Post Translational Modifications ◽  
Reactive Protein ◽  
Glycation End Products ◽  
Direct Mass Spectrometry

Abstract In living systems, nucleophilic amino acid residues are prone to non-enzymatic post-translational modification by electrophiles. α-Dicarbonyl compounds are a special type of electrophiles that can react irreversibly with lysine, arginine, and cysteine residues via complex mechanisms to form post-translational modifications known as advanced glycation end-products (AGEs). Glyoxal, methylglyoxal, and 3-deoxyglucosone are the major endogenous dicarbonyls, with methylglyoxal being the most well-studied. There are several routes that lead to the formation of dicarbonyl compounds, most originating from glucose and glucose metabolism, such as the non-enzymatic decomposition of glycolytic intermediates and fructosyl amines. Although dicarbonyls are removed continuously mainly via the glyoxalase system, several conditions lead to an increase in dicarbonyl concentration and thereby AGE formation. AGEs have been implicated in diabetes and aging-related diseases, and for this reason the elucidation of their structure as well as protein targets is of great interest. Though the dicarbonyls and reactive protein side chains are of relatively simple nature, the structures of the adducts as well as their mechanism of formation are not that trivial. Furthermore, detection of sites of modification can be demanding and current best practices rely on either direct mass spectrometry or various methods of enrichment based on antibodies or click chemistry followed by mass spectrometry. Future research into the structure of these adducts and protein targets of dicarbonyl compounds may improve the understanding of how the mechanisms of diabetes and aging-related physiological damage occur.

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