Interaction of poor sleep quality, family history of type 2 diabetes, and abdominal obesity on impaired fasting glucose: a population-based cross-sectional survey in China

2015 ◽  
Vol 36 (3) ◽  
pp. 277-282
Author(s):  
Yu Qin ◽  
Peian Lou ◽  
Peipei Chen ◽  
Lei Zhang ◽  
Pan Zhang ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Family History ◽  
Fasting Glucose ◽  
Population Based ◽  
Poor Sleep ◽  
Poor Sleep Quality ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
History Of

scholarly journals Differential expression of micro RNA-29 family in non-diabetic adults of diabetic and non-diabetic parents

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Uzair Abbas ◽  
Bushra Imdad ◽  
Sikander Adil Mughal ◽  
Israr Ahmed Baloch ◽  
Afshan Mehboob Khan ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Family History ◽  
Positive Family History ◽  
Cross Sectional Study ◽  
Vital Role ◽  
Micro Rna ◽  
Cross Sectional ◽  
Family History Of Diabetes ◽  
History Of

Abstract Objective MicroRNAs are known to regulate 60% of genes at post translational level. MicroRNAs including Micro RNA-29 family play a vital role in cellular activities and have validate role in numerous metabolic disorders inclusive of diabetes mellitus and its complications. While micro RNA profile changes years before the occurrence of disease. This cross-sectional study was conducted in non-diabetic adults of diabetic and non-diabetic parents to explore the early changes in expression of micro RNA-29 family as it can be served as early biomarker of type 2 diabetes in non-diabetic adults. This study was conducted from January 2019 to January 2021. Micro RNA was extracted from plasma of 50 participants and expression was compared through qPCR. While data was analyzed through SPSS version 21.0. Results 29a and 29b had lower expression in participants with family history of DM compared to those having no family history of DM (P < 0.0001). While micro RNA 29c was found to be significantly higher in participants with positive family history of type 2 diabetes as compared to those without family history of diabetes (P = 0.001).

scholarly journals Family history of type 2 diabetes: A population-based screening tool for prevention?

2006 ◽  
Vol 8 (2) ◽  
pp. 102-108 ◽  
Author(s):  
Susan Hariri ◽  
Paula W Yoon ◽  
Nadeem Qureshi ◽  
Rodolfo Valdez ◽  
Maren T Scheuner ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Family History ◽  
Screening Tool ◽  
Population Based ◽  
History Of

scholarly journals We are Family

2010 ◽  
Vol 8 (1) ◽  
pp. 88-97 ◽  
Author(s):  
Alexander Omolafe ◽  
Michele Mouttapa ◽  
Shari McMahan ◽  
Sora Park Tanjasiri
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Family History ◽  
African Americans ◽  
Positive Family History ◽  
Self Report ◽  
Cross Sectional ◽  
History Of

This cross-sectional study sought to describe an association between family history of type-2 diabetes and the awareness of risk factors, perceived threat and physical activity levels in African Americans. With a prevalence of 11.8%, African Americans remain disproportionately affected by the epidemic of diabetes. A risk factor that cannot be modified, but is important and closely linked with diabetes expression, family history, can be a considerable tool in promoting behavior change and reducing the risk of developing the condition in African Americans. A self-report questionnaire was administered to 133 church going African Americans, with 55 of them with a positive family history of type-2 diabetes (41.4%) and 78 (58.6%) without. None of the participants had been previously been diagnosed with type-2 diabetes. The results from the study indicated that African Americans with positive family history had a greater knowledge of risk factors, were more likely to indicate that their concern about the disease influences their eating habits and physical activity, and engaged in significantly more physical activity than those with no family history.

scholarly journals Life style factors associated with the risk of type 2 diabetes mellitus

2019 ◽  
Vol 1 (2) ◽  
pp. 77-83 ◽  
Author(s):  
Bikash Shrestha ◽  
Bipin Nepal ◽  
Yagya Laxmi Shakya ◽  
Binaya Regmi
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Family History ◽  
Alcohol Use ◽  
Modifiable Risk Factors ◽  
Cross Sectional ◽  
History Of

 Introduction: Type 2 diabetes mellitus is the commonest form of diabetes affecting more than 90% of the diabetic population worldwide. The prevalence of type 2 diabetes and its complications are increasing in the world, including developing nations like Nepal. This study aimed to determine the association between the lifestyle risk factors and the risk of type 2 diabetes mellitus in Nepalese population. Methods: This is hospital based cross sectional observational study done in the urban area of Nepal. Records of clients coming for the general health checkup in Grande International Hospital were evaluated in this study. Comparisons of the lifestyle factors in participants having and not having type 2 diabetes mellitus were done. Results: Significant associations with diagnosis of diabetes mellitus (DM) type 2 were seen in age (P ≤ 0.001), associated hypertension (P ≤ 0.001), dyslipidemia, family history of DM (P ≤ 0.001), alcohol use (P ≤ 0.001), and tobacco use (P ≤ 0.001). Logistic regression analysis showed that the odds of having diabetes were high in age group above 40 (OR – 6.9, CI 3.82 – 12.47), history of hypertension (OR- 3.84, CI 2.42 – 6.08), tobacco users (OR-2.26, CI 1.12 – 4.53), alcohol users (OR-3.99, CI 2.47 – 6.44), family history of DM (OR-2.44, CI 1.53 – 3.89), and abdominal obesity in both males (OR-3.9, CI 2 – 7.4) and females (OR-9.6, CI 3.78 – 24.35). Conclusions: The modifiable risk factors - obesity, smoking and alcohol use carry significant risks of developing type 2 diabetes. These red flag signs call for urgent attention to look for and rectify the modifiable risk factors in Nepalese population to prevent diabetes.

scholarly journals Characterizing risk of type 2 diabetes in First Nations people living in First Nations communities in Ontario: a population-based analysis using cross-sectional survey data

CMAJ Open ◽  
2020 ◽  
Vol 8 (1) ◽  
pp. E178-E183
Author(s):  
Laura C. Rosella ◽  
Kathy Kornas ◽  
Michael E. Green ◽  
Baiju R. Shah ◽  
Jennifer D. Walker ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
First Nations ◽  
Survey Data ◽  
Population Based ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Nations People ◽  
First Nations People

scholarly journals A family history of type 2 diabetes as a predictor of fatty liver disease in diabetes-free individuals with excessive body weight

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Giovanni De Pergola ◽  
Fabio Castellana ◽  
Roberta Zupo ◽  
Sara De Nucci ◽  
Francesco Panza ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Liver Disease ◽  
Family History ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Excess Weight ◽  
Cross Sectional ◽  
Alcoholic Fatty Liver ◽  
History Of

AbstractComprehensive screening for non-alcoholic fatty liver disease (NAFLD) may help prompt clinical management of fatty liver disease. A family history, especially of diabetes, has been little studied as a predictor for NAFLD. We characterized the cross-sectional relationship between a family history of type 2 diabetes (FHT2D) and NAFLD probability in 1185 diabetes-free Apulian (Southern-Italy) subjects aged > 20 years with overweight or obesity not receiving any drug or supplementation. Clinical data and routine biochemistry were analysed. NAFLD probability was defined using the fatty liver index (FLI). A first-degree FHT2D was assessed by interviewing subjects and assigning a score of 0, 1, or 2 if none, only one, or both parents were affected by type 2 diabetes mellitus (T2DM). Our study population featured most females (70.9%, N = 840), and 48.4% (N = 574) of the sample had first-degree FHT2D. After dividing the sample by a FHT2D, we found a higher BMI, Waist Circumference (WC), and diastolic blood pressure shared by FHT2D subjects; they also showed altered key markers of glucose homeostasis, higher triglyceride levels, and worse liver function. FLI scores were significantly lower in subjects without a first-degree FHT2D. After running logistic regression models, a FHT2D was significantly associated with the NAFLD probability, even adjusting for major confounders and stratifying by age (under and over 40 years of age). A FHT2D led to an almost twofold higher probability of NAFLD, regardless of confounding factors (OR 2.17, 95% CI 1.63 to 2.89). A first-degree FHT2D acts as an independent determinant of NAFLD in excess weight phenotypes, regardless of the age group (younger or older than 40 years). A NAFLD risk assessment within multidimensional screening might be useful in excess weight subjects reporting FHT2D even in the absence of diabetes.

scholarly journals Prevalence of depression among patients with type 2 diabetes mellitus: a cross-sectional study

2019 ◽  
Vol 6 (5) ◽  
pp. 1372
Author(s):  
Sanjay Parihar ◽  
Rajesh Singh
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Family History ◽  
Age Group ◽  
Duration Of Treatment ◽  
Cross Sectional ◽  
Prevalence Of Depression ◽  
History Of

Background: Depression can be viewed as a modifiable independent risk factor for the development of T2DM and for progression of complications from either type 1 or type 2 diabetes. The recognition and addressal of this association can have profound implications for prevention and treatment of these disorders. Objectives of this study the prevalence of depression among patients with diabetes mellitus type 2.Methods: A semi-structured questionnaire was used to collect the sociodemographic profile and the details of the diabetes and its treatment and history of other chronic diseases. Beck depression inventory (BDS-II) was used for evaluation of depression and 8 item Morisky medication adherence scale (MMAS-8) was used for measurement of patient’s adherence to medication.Results: Majority of the potential cases of depression (33%) were in the age group of 51-60 years. 62% of the patients were male. Majority of the patients (40%) were in the age group of 51-60 years. 73.4% of the married patients were potential cases of depression. 78% of the patients were having family history of type 2 diabetes mellitus. Majority of the patients (72%) were overweight or obese (BMI> 25kg/m2).Conclusion: Duration of diabetes and duration of treatment was 5-10 years in majority of the patients and were significantly associated with prevalence of depression. Prevalence of depression was associated with sex, religion, and family history but was not statistically significant.

scholarly journals Sleep Quality and Associated Factors Among Type 2 Dm Patients and Non-Dm Individuals in Bahir Dar Governmental Hospitals: Comparative Cross-Sectional Study

2021 ◽  
Author(s):  
Dagmawit Zewdu ◽  
Haileyesus Gedamu ◽  
Yeshiwork Beyene ◽  
Mekdes Tadesse ◽  
Mahlet Tamirat ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Sleep Quality ◽  
Associated Factors ◽  
Cross Sectional Study ◽  
Poor Sleep ◽  
Bahir Dar ◽  
Poor Sleep Quality ◽  
Cross Sectional ◽  
Type 2 Diabetic

Abstract Background: Multiple factors may contribute to sleep disruption in type 2 diabetic individuals. Sleep disruption in type 2 diabetic individuals is frequently associated with long-term damage, dysfunction, and failure of different organs. Nevertheless, literature in this regard is scanty in Ethiopia. Therefore, this study aimed to assess and compare the prevalence of poor sleep quality and associated factors among type 2 diabetic and non-diabetic individuals in Bahir Dar governmental hospitals.Methods: Comparative cross-sectional study was employed among 292 individuals with type 2 diabetes and 291 non-diabetic individuals in Bahir Dar governmental hospitals from March 01- to April-01. A two-stage cluster sampling method was employed to select participants. Pittsburgh sleep quality index was used for assessing sleep quality. For analysis, descriptive and summary statistics were used to determine the prevalence and percentage of variables. Chi-square test was also used for comparison. Binary logistic regression analysis was employed to determine the associated factors of poor sleep quality. Result: The prevalence of poor sleep was 50.7% (95% CI; 44.9-56.2) and 31.8% (95% CI 26.5-37.5) among individuals with type 2 diabetes and non-diabetic individuals respectively. Among the overall participants being type 2 diabetic patient was also found significantly associated with poor sleep quality as compared to non-diabetic individuals (AOR=1.89; 95% CI; 1.19-2.87). Comorbidity, duration of DM >10 years, Poor glycaemic control, having depression, low physical activity, and poor social support were factors significantly associated with poor sleep quality among individuals with type 2 diabetes. Among non-diabetic individual’s low physical activity, poor social support, having depression, and age group (>50 years) were factors significantly associated with poor sleep quality. Conclusion: In this study, the prevalence of poor sleep among individuals with type 2 diabetes was higher than non-diabetes individuals.

scholarly journals Traditional and complementary medicine use in patients with type 2 diabetes: Findings from a multicenter cross-sectional questionnaire survey in Selangor, Malaysia

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Yieng Yii Wong ◽  
Azizul Hakim Sulaiman ◽  
Anis Aeida Mat Jaya ◽  
Pei Zan Wan ◽  
Anchaya Eh Wan ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Complementary Medicine ◽  
High Rate ◽  
Herbal Remedies ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Family History Of Diabetes ◽  
Patients With Diabetes ◽  
History Of

Current global estimates of traditional and complementary medicine (T&CM) utilization range from 9.8% to 76%, with high rates of use being documented in Japan, South Korea, and Malaysia. Previous research has shown that patients with diabetes are more likely to use T&CM than individuals without diabetes. A multicenter cross-sectional survey of patients with type 2 diabetes mellitus was conducted at five primary care health clinics in Petaling district of Selangor, Malaysia from June 1, 2020 through September 30, 2020. A total of 476 patients were enrolled. 58.0% of men and 64.8% of women reported to use at least a type of T&CM. The prevalence of T&CM use among Malays, Chinese, and Indians was 71.1%, 33.3%, and 62.9% respectively. The most commonly used T&CM were herbal remedies (45.2%), followed by nutritional supplements (9.9%). 80.0% of the patients would follow their doctor’s instruction if the doctor asked them not to use T&CM, whereas 70.2% would consult their doctor about using T&CM. Factors associated with higher tendency for T&CM use comprised increased age, unemployed, oral antidiabetic monotherapy, presence of family history of diabetes, and coexisting chronic disease. T&CM therapies were common among multi-ethnic patient population with type 2 diabetes. The high rate of use warranted clinical attention and intervention to reduce the risk of drug-associated adverse events.

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