scholarly journals Life style factors associated with the risk of type 2 diabetes mellitus

2019 ◽  
Vol 1 (2) ◽  
pp. 77-83 ◽  
Author(s):  
Bikash Shrestha ◽  
Bipin Nepal ◽  
Yagya Laxmi Shakya ◽  
Binaya Regmi

 Introduction: Type 2 diabetes mellitus is the commonest form of diabetes affecting more than 90% of the diabetic population worldwide. The prevalence of type 2 diabetes and its complications are increasing in the world, including developing nations like Nepal. This study aimed to determine the association between the lifestyle risk factors and the risk of type 2 diabetes mellitus in Nepalese population. Methods: This is hospital based cross sectional observational study done in the urban area of Nepal. Records of clients coming for the general health checkup in Grande International Hospital were evaluated in this study. Comparisons of the lifestyle factors in participants having and not having type 2 diabetes mellitus were done. Results: Significant associations with diagnosis of diabetes mellitus (DM) type 2 were seen in age (P ≤ 0.001), associated hypertension (P ≤ 0.001), dyslipidemia, family history of DM (P ≤ 0.001), alcohol use (P ≤ 0.001), and tobacco use (P ≤ 0.001). Logistic regression analysis showed that the odds of having diabetes were high in age group above 40 (OR – 6.9, CI 3.82 – 12.47), history of hypertension (OR- 3.84, CI 2.42 – 6.08), tobacco users (OR-2.26, CI 1.12 – 4.53), alcohol users (OR-3.99, CI 2.47 – 6.44), family history of DM (OR-2.44, CI 1.53 – 3.89), and abdominal obesity in both males (OR-3.9, CI 2 – 7.4) and females (OR-9.6, CI 3.78 – 24.35). Conclusions: The modifiable risk factors - obesity, smoking and alcohol use carry significant risks of developing type 2 diabetes. These red flag signs call for urgent attention to look for and rectify the modifiable risk factors in Nepalese population to prevent diabetes.

2019 ◽  
Vol 6 (5) ◽  
pp. 1372
Author(s):  
Sanjay Parihar ◽  
Rajesh Singh

Background: Depression can be viewed as a modifiable independent risk factor for the development of T2DM and for progression of complications from either type 1 or type 2 diabetes. The recognition and addressal of this association can have profound implications for prevention and treatment of these disorders. Objectives of this study the prevalence of depression among patients with diabetes mellitus type 2.Methods: A semi-structured questionnaire was used to collect the sociodemographic profile and the details of the diabetes and its treatment and history of other chronic diseases. Beck depression inventory (BDS-II) was used for evaluation of depression and 8 item Morisky medication adherence scale (MMAS-8) was used for measurement of patient’s adherence to medication.Results: Majority of the potential cases of depression (33%) were in the age group of 51-60 years. 62% of the patients were male. Majority of the patients (40%) were in the age group of 51-60 years. 73.4% of the married patients were potential cases of depression. 78% of the patients were having family history of type 2 diabetes mellitus. Majority of the patients (72%) were overweight or obese (BMI> 25kg/m2).Conclusion: Duration of diabetes and duration of treatment was 5-10 years in majority of the patients and were significantly associated with prevalence of depression. Prevalence of depression was associated with sex, religion, and family history but was not statistically significant.


Author(s):  
Subha Sankha Kundu ◽  
Kunal Kanti Majumdar ◽  
Dipankar Mukherjee ◽  
Rajib Sikder ◽  
Rituraj Dey ◽  
...  

Background: With the change in lifestyle and behavior among individuals, the prevalence of T2DM is on rise. Many modifiable and non-modifiable risk factors are attributable for the cardiovascular morbidity among the diabetics which is the leading cause of mortality and morbidity among them, also increasing their burden of expenditure. The purpose of this study was to determine the prevailing factors responsible and its associate co morbidities among the Type 2 Diabetes Mellitus patients.Methods: It was a descriptive, observational and cross sectional study conducted for 30 days. 226 patients who visited the diabetes OPD of the Medical College were interviewed using a pre-designed questionnaire, anthropometric measurements, systemic and general examinations were performed. The data was analysed using suitable statistical analysis.Results: Out of 226 patients, 47.8% were suffering from cardiovascular morbidity, majority being heart failure (57.4%). Most of them were contributed 46.3% and 38.9% by age group 50-59 years (46.3%) and 60-69 years (38.9%), 55.6% were smokers and 64.4% were overweight. 70.4% complained of stress in their daily life while 48.1% were unaware of their heart conditions until checkup. 18.5% of the patients also suffered from retinopathy and 37.03% from diabetic foot ulcer. 64% of them had hypertension and 67.2% had sedentary life style.Conclusions: Many modifiable and non-modifiable risk factors were found associated with cardiovascular morbidity among the type 2 diabetes mellitus patients. So a proper awareness and life style modifications might be necessary to decrease cardiovascular morbidity among them.


2017 ◽  
Vol 9 (9) ◽  
pp. 42
Author(s):  
Sana Arshad ◽  
Sania Tahir ◽  
Bilal Tahir ◽  
Nazia Tahir ◽  
Tahir Rasool ◽  
...  

BACKGROUND: Diabetes is the leading cause of morbidity and mortality amongst the people of Pakistan. In 2015, 7 million people had diabetes and the number is still on raise. Family history of diabetes, high body mass index, and other sociodemographic factors are the risk factors of diabetes. Persistent exposure to excessive glucose may be a reason behind diabetic complications like nephropathy, neuropathy, retinopathy, cardiomyopathy and gestational diabetes mellitus.METHODS: For the evaluation of laboratory parameters, 600 blood samples were collected at Akhuwat Diabetic Centre and from Jinnah Hospital, Lahore. Demographic data of the participants was collected by filling a questionnaire. Lipid profile, liver enzymes, and renal function tests were performed and statistical analysis was done.RESULTS: Type 2 diabetes mellitus among other types is the most prevalent form of diabetes in our population. Family history of diabetes (p=0.002), Body Mass Index (>25) p<0.001, high cholesterol (p=0.04), high triglyceride p<0.001, high LDL p<0.001 and low HDL p<0.001 are significantly associated with the incidence of diabetes. Hypertension among the other comorbidities is more common in diabetic patients.CONCLUSION: Type 2 Diabetes Mellitus is highly prevalent in the local population. Improved lifestyle and proper medical monitoring can help to manage diabetes in our population.


2007 ◽  
Vol 23 (5) ◽  
pp. 259-266 ◽  
Author(s):  
Marsha Howell Adams ◽  
Carol Ann Barnett Lammon

Type 2 diabetes mellitus is reaching epidemic proportions among children and adolescents. School health fairs offer an opportunity to identify children with risk factors for the development of type 2 diabetes mellitus. This study identified selected risk factors (i.e., high-risk racial/ethnic group, obesity, elevated blood pressure, elevated casual blood glucose, elevated total cholesterol, and the presence of acanthosis nigricans) for development of type 2 diabetes mellitus in rural children with or without a family history of diabetes during annual school health fairs. Of the children screened, 40% (673) presented with two or more of the identified risk factors for type 2 diabetes mellitus. The presence of multiple risk factors in participants reporting a positive family history of diabetes mellitus versus those with no family history was not statistically significant. Based on the study results, factors other than family history may be more predictive for the development of type 2 diabetes mellitus in rural school children.


1970 ◽  
Vol 42 (2) ◽  
pp. 137-141
Author(s):  
T Jaja ◽  
IE Yarhere

Background: The prevalence of Type 2 diabetes mellitus (T2 DM) in children and adolescents is on the increase, therefore, prevention and early detection are important.Objective: To assess for easily identifiable risk factors (overweight/obesity, hypertension, Impaired Fasting Glucose (IFG) and family history of diabetes) for T2DM in adolescents in public secondary schoolsResult: Eight hundred and eighty adolescents aged 10 to 19 years were screened and 124(14.1%) were overweight/obese. 457 (51.9%) of students had none of the risk factors while 272(30.9%) had at least one risk factor. Using the American Diabetes Association criteria for identification of those at risk for T2DM, 21(2.4%) were identified. The frequency of presence of risk factors was more in females (3.3%), mid adolescent age group (3.1%) and those with positive family history of diabetes. These findings were however not statistically significant. There was a statistically significant association between presence of hypertension and impaired fasting glucose and risk factor for type 2 DM.Conclusion: The significant risk factors identified in this study were prehypertension/hypertension and impaired fasting blood glucose.Key words: Adolescence, Risk factors, Type 2 diabetes mellitus


2019 ◽  
Vol 10 ◽  
pp. 204201881986007 ◽  
Author(s):  
Saeed M. Omar ◽  
Imad R. Musa ◽  
Amir ElSouli ◽  
Ishag Adam

Background: Diabetes mellitus (DM) constitutes a global health threat and burden, especially in developing countries. We conducted a cross-sectional study in Gadarif in eastern Sudan to evaluate the prevalence and glycaemic control of patients with type 2 diabetes mellitus (T2DM). Methods: We performed a cross-sectional community-based study. Data on blood glucose levels, and anthropometric, demographic and clinical history data were obtained. Results: Six hundred Sudanese adults with a mean (SD) age of 44.9 (16.5) years were enrolled. More than two-thirds (70.3%) of the study participants were women. The prevalence of T2DM, newly diagnosed T2DM and uncontrolled T2DM was 20.8%, 10.0% and 80.0%, respectively. Logistic regression analysis showed no significant association between education, marital status, body mass index, waist circumference and DM. However older age (AOR = 4.88, 95% CI = 3.09–7.70) and a family history of DM (AOR = 2.58, 95% CI = 1.59–4.20) were associated with T2DM. Conclusion: The prevalence of T2DM is high among the Sudanese population, especially in older people and those with a family history of DM. The high prevalence of uncontrolled DM in this setting is another hidden burden.


2017 ◽  
pp. 35-44
Author(s):  
Dinh Toan Nguyen

Background: Studies show that diabetes mellitus is the greatest lifestyle risk factor for dementia. Appropriate management and treatment of type 2 diabetes mellitus could prevent the onset and progression of mild cognitive impairment to dementia. MoCA test is high sensitivity with mild dementia but it have not been used and studied widespread in Vietnam. Aim: 1. Using MoCA and MMSE to diagnose dementia in patients with type 2 diabetes mellitus. 2. Assessment of the relationship between dementia and the risk factors. Methods: cross-sectional description in 102 patients with type 2 diabetes mellitus. The Mini-Mental State Examination(MMSE) and the Montreal Cognitive Assessment (MoCA) were used to assess cognitive function. The diagnosis of dementia was made according to Diagnostic and Statistical Manual of Mental Disorders. Results: The average value for MoCA in the group of patients with dementia (15.35 ± 2.69) compared with non-dementia group (20.72 ± 4.53). The sensitivity and specificity of MoCA were 84.8% and 78.3% in identifying individuals with dementia, and MMSE were 78.5% and 82.6%, respectively. Using DSMIV criteria as gold standard we found MoCA and MMSE were more similar for dementia cases (AUC 0.871 and 0.890). The concordance between MoCA and MMSE was moderate (kappa = 0.485). When considering the risk factors, the education,the age, HbA1c, dyslipidemia, Cholesterol total related with dementia in the type 2 diabetes. Conclusion: MoCA scale is a good screening test of dementia in patients with type 2 diabetes mellitus.When compared with the MMSE scale, MoCA scale is more sensitive in detecting dementia. Key words: MoCA, dementia, type 2 diabetes mellitus, risk factors


2021 ◽  
Vol 49 (5) ◽  
pp. 030006052110166
Author(s):  
Yuan Wang ◽  
Hua Gao ◽  
Wen Di ◽  
Zhuowei Gu

Objective We aimed to investigate whether patients with polycystic ovary syndrome (PCOS) and a family history (FH) of type 2 diabetes mellitus (T2DM) are at increased risk of endocrinological and metabolic abnormalities, and whether this risk differs between first-degree and second-degree relatives, and between maternal and paternal transmission. Methods A total of 680 patients with PCOS were enrolled in this retrospective, single-center study. Endocrine and glycolipid metabolism parameters were compared. Results The free androgen index (FAI), and levels of fasting blood glucose (FBG), fasting insulin (FINS), homeostatic model assessment-insulin resistance (HOMA-IR), total cholesterol (TC), and low-density lipoprotein cholesterol were significantly higher, whereas sex hormone binding globulin (SHBG) levels were significantly lower in patients with PCOS and a FH of T2DM. In patients with PCOS with a FH of T2DM in first-degree relatives, age and levels of FBG, FINS, and HOMA-IR were significantly higher than those who had a FH of T2DM in second-degree relatives. A maternal history of T2DM was associated with a higher body mass index, FAI, and TG levels, and lower SHBG levels. Conclusions Patients with PCOS and a FH of T2DM have more severe hyperandrogenism and metabolic disorders, especially in those with maternal transmission.


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