Bacteria and fungi associated with dead boll weevils (Anthonomus grandis) in a natural population

1966 ◽  
Vol 8 (3) ◽  
pp. 401-408 ◽  
Author(s):  
R.E. McLaughlin ◽  
M.R. Bell ◽  
Smiley Dodgen Veal
Keyword(s):  
Natural Population ◽  
Anthonomus Grandis ◽  
Bacteria And Fungi

Antagonism against phytopathogenic bacteria and fungi and phytoregulating activity of streptomycetes of chernozems Moldova

2019 ◽  
Vol 326 (1) ◽  
pp. 131-136
Author(s):  
S.A. Burtseva ◽  
◽  
M.N. Byrsa ◽  
S.N. Maslobrod ◽  
◽  
...  
Keyword(s):  
Phytopathogenic Bacteria ◽  
Bacteria And Fungi

Reproduction of the Roman snail (Helix pomatia L.) from a local natural population in farm conditions and in a natural habitat

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Maciej Ligaszewski ◽  
Przemysław Pol
Keyword(s):  
Natural Population ◽  
Natural Habitat ◽  
Local Population ◽  
Helix Pomatia ◽  
Second Phase ◽  
Animal Reproduction ◽  
Snail Helix Pomatia ◽  
June July ◽  
A Site

AbstractThe aim of this study was to compare the quality of clutches and reproduction results of two groups of Roman snails (Helix pomatia) from the same local population, laying eggs simultaneously in semi-natural farm conditions and in a natural habitat. The study material were Roman snails aged 2 or more years which had entered the third phenological season of their life and thus the first season of sexual maturity. Observations were conducted at an earthen enclosure in a greenhouse belonging to the experimental farm for edible snails at the National Research Institute of Animal Reproduction in Balice near Kraków (Poland) as well as at a site where a local population naturally occurs in the uncultivated park surrounding the Radziwiłł Palace. In the June-July season, differences among such parameters as weight of clutch, number of eggs in clutch, mean egg weight, and hatchling percentage when compared to the total number of eggs in the clutch were compared. It was determined that clutches of eggs from the natural population laid in the greenhouse were of lesser weight (P<0.01), contained fewer eggs (P<0.05), and the mean weight of individual eggs was less (P<0.05) than in clutches laid simultaneously in a natural habitat. Both in the greenhouse and the natural habitat, in the first phase of laying eggs (June) the weight of the clutch and number of eggs its contained were greater than in the second phase (July). However, only for snails laying eggs in the greenhouse were these differences statistically significant (P<0.05) and highly significant (P<0.01), respectively. Statistically significant differences were not observed in hatchling percentage between eggs laid in the greenhouse and the natural habitat. The lower number of eggs laid in the farmed conditions of the greenhouse was successfully compensated for by the absence of mass destruction by rodents which occurred in the natural habitat.

Identification of SSR Markers Linked to Oil Content in Peanut (Arachis hypogaea L.) through RIL Population and Natural Population

2012 ◽  
Vol 37 (11) ◽  
pp. 1967-1974 ◽  
Author(s):  
Li HUANG ◽  
Xin-Yan ZHAO ◽  
Wen-Hua ZHANG ◽  
Zhi-Ming FAN ◽  
Xiao-Ping REN ◽  
...  
Keyword(s):  
Natural Population ◽  
Arachis Hypogaea ◽  
Ssr Markers ◽  
Oil Content ◽  
Ril Population

Insights into Potent Therapeutical Antileukemic Agent L-glutaminase Enzyme Under Solid-state Fermentation: A Review

2020 ◽  
Vol 21 (3) ◽  
pp. 211-220 ◽  
Author(s):  
Chandrasai Potla Durthi ◽  
Madhuri Pola ◽  
Satish Babu Rajulapati ◽  
Anand Kishore Kola
Keyword(s):  
Solid State ◽  
Solid State Fermentation ◽  
Food Industry ◽  
Energy Requirement ◽  
Production Studies ◽  
Wide Range ◽  
Hybridoma Technology ◽  
Bacteria And Fungi ◽  
The Stability ◽  
Glutaminase Activity

Aim & objective: To review the applications and production studies of reported antileukemic drug L-glutaminase under Solid-state Fermentation (SSF). Overview: An amidohydrolase that gained economic importance because of its wide range of applications in the pharmaceutical industry, as well as the food industry, is L-glutaminase. The medical applications utilized it as an anti-tumor agent as well as an antiretroviral agent. L-glutaminase is employed in the food industry as an acrylamide degradation agent, as a flavor enhancer and for the synthesis of theanine. Another application includes its use in hybridoma technology as a biosensing agent. Because of its diverse applications, scientists are now focusing on enhancing the production and optimization of L-glutaminase from various sources by both Solid-state Fermentation (SSF) and submerged fermentation studies. Of both types of fermentation processes, SSF has gained importance because of its minimal cost and energy requirement. L-glutaminase can be produced by SSF from both bacteria and fungi. Single-factor studies, as well as multi-level optimization studies, were employed to enhance L-glutaminase production. It was concluded that L-glutaminase activity achieved by SSF was 1690 U/g using wheat bran and Bengal gram husk by applying feed-forward artificial neural network and genetic algorithm. The highest L-glutaminase activity achieved under SSF was 3300 U/gds from Bacillus sp., by mixture design. Purification and kinetics studies were also reported to find the molecular weight as well as the stability of L-glutaminase. Conclusion: The current review is focused on the production of L-glutaminase by SSF from both bacteria and fungi. It was concluded from reported literature that optimization studies enhanced L-glutaminase production. Researchers have also confirmed antileukemic and anti-tumor properties of the purified L-glutaminase on various cell lines.

Novel Thiazole-Based Thiazolidinones as Potent Anti-infective Agents: In silico PASS and Toxicity Prediction, Synthesis, Biological Evaluation and Molecular Modelling

2020 ◽  
Vol 23 (2) ◽  
pp. 126-140 ◽  
Author(s):  
Christophe Tratrat
Keyword(s):  
In Silico ◽  
Antimicrobial Agents ◽  
Target Identification ◽  
Biological Evaluation ◽  
Microbial Infection ◽  
Toxicity Prediction ◽  
Discovery Studio ◽  
Bacteria And Fungi ◽  
Multiple Drugs ◽  
Antibacterial And Antifungal

Aims and Objective: The infectious disease treatment remains a challenging concern owing to the increasing number of pathogenic microorganisms associated with resistance to multiple drugs. A promising approach for combating microbial infection is to combine two or more known bioactive heterocyclic pharmacophores in one molecular platform. Herein, the synthesis and biological evaluation of novel thiazole-thiazolidinone hybrids as potential antimicrobial agents were dissimilated. Materials and Methods: The preparation of the substituted 5-benzylidene-2-thiazolyimino-4- thiazolidinones was achieved in three steps from 2-amino-5-methylthiazoline. All the compounds have been screened in PASS antibacterial activity prediction and in a panel of bacteria and fungi strains. Minimum inhibitory concentration and minimum bacterial concentration were both determined by microdilution assays. Molecular modeling was conducted using Accelrys Discovery Studio 4.0 client. ToxPredict (OPEN TOX) and ProTox were used to estimate the toxicity of the title compounds. Results: PASS prediction revealed the potentiality antibacterial property of the designed thiazolethiazolidinone hybrids. All tested compounds were found to kill and to inhibit the growth of a vast variety of bacteria and fungi, and were more potent than the commercial drugs, streptomycin, ampicillin, bifomazole and ketoconazole. Further, in silico study was carried out for prospective molecular target identification and revealed favorable interaction with the target enzymes E. coli MurB and CYP51B of Aspergillus fumigatus. Toxicity prediction revealed that none of the active compounds was found toxic. Conclusion: Substituted 5-benzylidene-2-thiazolyimino-4-thiazolidinones, endowing remarkable antibacterial and antifungal properties, were identified as a novel class of antimicrobial agents and may find a potential therapeutic use to eradicate infectious diseases.

Design, Synthesis, Antimicrobial Evaluation and Molecular Modeling Study of New 2-mercaptoimidazoles (Series-III)

2019 ◽  
Vol 16 (5) ◽  
pp. 512-521 ◽  
Author(s):  
Nidhi Rani ◽  
Randhir Singh
Keyword(s):  
Sulfonic Acid ◽  
Docking Study ◽  
Molecular Docking Study ◽  
One Pot ◽  
Design Synthesis ◽  
Toluene Sulfonic Acid ◽  
Antimicrobial Evaluation ◽  
Bacteria And Fungi ◽  
High Yields ◽  
Antimicrobial Potency

Background: A series of novel substituted 2-mercaptoimidazoles was synthesised efficiently and in high yields using one-pot synthesis from m-hydroxyacetophenones. Methods: The structures of the newly synthesized compounds were established, their molecular activity was investigated against some bacteria and fungi were further validated using molecular docking study. Results: Reaction of o-hydroxyphenacylbromide (2) with substituted aniline and KSCN, in the presence of catalyst p-toluene sulfonic acid afforded 4(a-r) in good yield. The structure of compounds (4a-r) was confirmed by IR, NMR and MS. Conclusion: The compounds exhibited excellent antimicrobial potency against the tested microorganism.

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