Antimicrobial properties of crude extracts of Moringa oleifera against some pathogenic bacteria and fungi isolated from different sites on human body

2020 ◽  
Vol 23 (09) ◽  
Author(s):  
Khamael Ali Kareem ◽  
Ammar Adnan Tuama ◽  
Intesar Kareem Abdul Hassan
Keyword(s):  
Human Body ◽  
Pathogenic Bacteria ◽  
Moringa Oleifera ◽  
Antimicrobial Properties ◽  
Crude Extracts ◽  
Bacteria And Fungi

scholarly journals Evaluation of antimicrobial activity of three important medicinal plants of South India

2019 ◽  
Vol 8 (1) ◽  
pp. 3484
Author(s):  
Gopalakrishnaiah B. ◽  
Aniel Kumar O.
Keyword(s):  
Antimicrobial Activity ◽  
Medicinal Plants ◽  
Pathogenic Bacteria ◽  
Antimicrobial Agents ◽  
Antimicrobial Properties ◽  
Development Program ◽  
Antimicrobial Effect ◽  
Trichophyton Mentagrophytes ◽  
Crude Extracts ◽  
The World

India is found to be a country with rich biodiversity and enormous treasure of herbal plants and consequently called as medicinal garden of the world. Plants are the richest source of natural antimicrobial agents. In recent years drug resistance to human pathogenic bacteria has been commonly reported from all over the world. Therefore, there is a need to develop alternative antimicrobial drugs for the treatment of infectious diseases; one approach is to screen local medicinal plants for possible antimicrobial properties. The present study was designed to evaluate the antimicrobial efficacy of hexane, chloroform and methanol crude extracts of the leaves of three important medicinal plants viz., Biophytum sensitivum (L.) DC, Bougainvillea spectabilis L. and Caesalpinia bonducella (L.) Fleming, collected from in and around Visakhapatnam District. The antimicrobial activity of the crude extracts was tested against three Gram Positive bacteria (Bacillus subtilis MTCC 441, Enterococcus faecalis MTCC 439, Staphylococcus aureus MTCC 737), Three Gram Negative bacteria (Escherichia coli MTCC 443, Proteus vulgaris MTCC 426 and Pseudomonas aeruginosa MTCC 1688) and three Fungal strains (Candida albicans MTCC 227, Epidermophyton floccosum MTCC 613 and Trichophyton mentagrophytes MTCC 7687) using agar well diffusion assay. Our results demonstrated that methanol extracts of these plants leaves have concentration dependent antibacterial activity against some of the tested organisms. Further studies should be undertaken to elucidate the exact mechanism of action of antimicrobial effect to identify the active ingredients which can be used for drug development program.

scholarly journals ANTIMICROBIAL PROPERTIES OF LANTHANUM ALUMINATE NANOPARTICLES

2016 ◽  
Vol 3 (1) ◽  
pp. 1-5
Author(s):  
Gayathri S ◽  
Ranjithkumar R ◽  
Balaganesh A.S ◽  
Chandar Shekar B
Keyword(s):  
Fungal Pathogens ◽  
Pathogenic Bacteria ◽  
Sol Gel ◽  
Trichoderma Viride ◽  
Antimicrobial Properties ◽  
Maximum Activity ◽  
Paper Disk ◽  
Filter Paper Disk ◽  
Test Organisms ◽  
Bacteria And Fungi

The sol-gel route synthesized LA-NPs were tested for antimicrobial properties against different human pathogenic bacteria and fungi. The test organisms used were clinical isolates viz., Streptococcus pyogenes, Staphylococcus aureus, Escherichia coli, Klebsiella nemoniae and the human fungal pathogens like Candida albicans and Trichoderma viride. The LA- NPs achieved maximum activity against S. aureus compared with other three tested organisms such as S. pyogenes, E. coli and K. pneumonia. It also showed very good antimicrobial properties against studied fungi. At the concentration 1 mg/ml LA-NPs impregnated filter paper disk achieved maximum activity against human pathogen.

scholarly journals Evaluation of Key Antimicrobial Properties of Moringa oleifera in Relation to Its Use as a Hand-Washing Product

Water ◽  
2018 ◽  
Vol 10 (9) ◽  
pp. 1154
Author(s):  
Jasmine Clark ◽  
Monica Jimenez ◽  
Enrique Raso ◽  
Loretta Antwi ◽  
Lawrence Ofosu-Appiah ◽  
...  
Keyword(s):  
Pathogenic Bacteria ◽  
Moringa Oleifera ◽  
Antibacterial Properties ◽  
Antimicrobial Properties ◽  
Hand Washing ◽  
Minimally Processed ◽  
Resource Limited ◽  
Set Up ◽  
Water Scarce

Moringa oleifera (M. oleifera) is a fast-growing, drought-resistant plant found throughout tropical and subtropical regions. A previous study found dry M. oleifera leaf powder to be similarly efficacious to non-medicated soap when used as a hand-wash, even without the use of water. These characteristics suggest that M. oleifera could serve as a potential hand-washing product in water and resource-limited contexts, such as humanitarian and emergency settings. The purpose of this study was to assess the efficacy of minimally processed M. oleifera sourced locally in Ghana as a hand-washing and antimicrobial product by assessing whether: (1) different preparations of M. oleifera have antibacterial properties against potential diarrheal pathogens through set-up of die-off studies; (2) M. oleifera is an effective hand-washing product by conducting an in-vivo trial with healthy volunteers; and (3) M. oleifera has antimicrobial properties in potentially reusable aqueous solutions, such as rinse water used for hand-washing. M. oleifera was found to be significantly less effective than non-medicated soap when tested as a hand-washing product and promoted the growth of bacteria in aqueous solution. Moreover, the Moringa used in the study was found to be host to pathogenic bacteria, reinforcing the idea that it is unsuitable to use as a hand-washing product. Accordingly, in its minimally processed form, M. oleifera appears to be an ineffective antimicrobial agent and its use as a hand-washing product in water-scarce and resource-limited settings is not recommended.

scholarly journals Preparation, Characterization, and Antimicrobial Properties of Chitosan–Silver Nanocomposites Films Against Fish Pathogenic Bacteria and Fungi

2017 ◽  
Vol 57 (4) ◽  
pp. 427-437 ◽  
Author(s):  
S. H. S. Dananjaya ◽  
D. C. M. Kulatunga ◽  
G. I. Godahewa ◽  
Chamilani Nikapitiya ◽  
Chulhong Oh ◽  
...  
Keyword(s):  
Pathogenic Bacteria ◽  
Antimicrobial Properties ◽  
Silver Nanocomposites ◽  
Bacteria And Fungi

scholarly journals The Glucosinolates: A Sulphur Glucoside Family of Mustard Anti-Tumour and Antimicrobial Phytochemicals of Potential Therapeutic Application

Biomedicines ◽  
2019 ◽  
Vol 7 (3) ◽  
pp. 62 ◽  
Author(s):  
James Melrose
Keyword(s):  
Pathogenic Bacteria ◽  
Antimicrobial Properties ◽  
Allyl Isothiocyanate ◽  
World Health Organisation ◽  
World Health ◽  
Antibiotic Resistant ◽  
Anti Cancer ◽  
Potential Therapeutic Application ◽  
Bacteria And Fungi

This study reviewed aspects of the biology of two members of the glucosinolate family, namely sinigrin and glucoraphanin and their anti-tumour and antimicrobial properties. Sinigrin and glucoraphanin are converted by the β-sulphoglucosidase myrosinase or the gut microbiota into their bioactive forms, allyl isothiocyanate (AITC) and sulphoraphanin (SFN) which constitute part of a sophisticated defence system plants developed over several hundred million years of evolution to protect them from parasitic attack from aphids, ticks, bacteria or nematodes. Delivery of these components from consumption of cruciferous vegetables rich in the glucosinolates also delivers many other members of the glucosinolate family so the dietary AITCs and SFN do not act in isolation. In vitro experiments with purified AITC and SFN have demonstrated their therapeutic utility as antimicrobials against a range of clinically important bacteria and fungi. AITC and SFN are as potent as Vancomycin in the treatment of bacteria listed by the World Health Organisation as antibiotic-resistant “priority pathogens” and also act as anti-cancer agents through the induction of phase II antioxidant enzymes which inactivate potential carcinogens. Glucosinolates may be useful in the treatment of biofilms formed on medical implants and catheters by problematic pathogenic bacteria such as Pseudomonas aeruginosa and Staphylococcus aureus and are potent antimicrobials against a range of clinically important bacteria and fungi. The glucosinolates have also been applied in the prevention of bacterial and fungal spoilage of food products in advanced atmospheric packaging technology which improves the shelf-life of these products.

scholarly journals Antimicrobial activities of herbal plants from Uzbekistan against human pathogenic microbes

2020 ◽  
Author(s):  
Dilfuza Egamberdieva ◽  
Dilfuza Jabborova ◽  
Svetlana Babich ◽  
Sokhiba Xalmirzaeva ◽  
Kamaliddin Salakhiddinov ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Traditional Medicine ◽  
Pathogenic Bacteria ◽  
Antimicrobial Properties ◽  
Multidrug Resistant ◽  
Antimicrobial Activities ◽  
Antibacterial And Antifungal Activities ◽  
Herbal Plants ◽  
Bacteria And Fungi ◽  
Antibacterial And Antifungal

AbstractIn traditional medicine of Uzbekistan, around 20% of herbal plants are used to treat various ailments, including diseases caused by pathogenic bacteria and fungi. Though conventional medicinal plants are common in Uzbekistan, many plant species potentially useful for new pharmaceuticals are less studied. They contain various biological compounds with antibacterial and antifungal activities, that could be developed into drugs. The search for novel antimicrobial compounds, especially against multidrug-resistant pathogens from aromatic and herbal plants is an essential scientific research line. However, the antimicrobial properties of several medicinally important plants from various countries are still unknown. This review aims to provide an up-to-date report on the antimicrobial activity of medicinal plants endemic to Uzbekistan widely used in traditional medicine.

Antimicrobial properties of actively purified secondary metabolites isolated from different marine organisms

2020 ◽  
Vol 21 ◽  
Author(s):  
Nilushi Indika Bamunu Arachchige ◽  
Fazlurrahman Khan ◽  
Young-Mog Kim
Keyword(s):  
Secondary Metabolites ◽  
Pathogenic Bacteria ◽  
Antimicrobial Agents ◽  
Bacterial Species ◽  
Antimicrobial Properties ◽  
Antimicrobial Effect ◽  
Cost Effective ◽  
Resistance Mechanisms ◽  
Marine Organisms ◽  
Antimicrobial Compounds

Background: The treatment of infection caused by pathogenic bacteria becomes one of the serious concerns globally. The failure in the treatment was found due to the exhibition of multiple resistance mechanisms against the antimicrobial agents. Emergence of resistant bacterial species has also been observed due to prolong treatment using conventional antibiotics. To combat these problems, several alternative strategies have been employed using biological and chemically synthesized compounds as antibacterial agents. Marine organisms considered as one of the potential sources for the isolation of bioactive compounds due to the easily available, cost-effective, and eco-friendly. Methods: The online search methodology was adapted for the collection of information related to the antimicrobial properties of marine-derived compounds. These compound has been isolated and purified by different purification techniques, and their structure also characterized. Furthermore, the antibacterial activities have been reported by using broth microdilution as well as disc diffusion assays. Results: The present review paper describes the antimicrobial effect of diverse secondary metabolites which are isolated and purified from the different marine organisms. The structural elucidation of each secondary metabolite has also been done in the present paper, which will help for the in silico designing of the novel and potent antimicrobial compounds. Conclusion: A thorough literature search has been made and summarizes the list of antimicrobial compounds that are isolated from both prokaryotic and eukaryotic marine organisms. The information obtained from the present paper will be helpful for the application of marine compounds as antimicrobial agents against different antibiotic-resistant human pathogenic bacteria.

A Review on Quantum Dots: Synthesis to In- silico Analysis as Next Generation Antibacterial Agents

2019 ◽  
Vol 20 (3) ◽  
pp. 255-262 ◽  
Author(s):  
Sounik Manna ◽  
Munmun Ghosh ◽  
Ranadhir Chakraborty ◽  
Sudipto Ghosh ◽  
Santi M. Mandal
Keyword(s):  
Quantum Dots ◽  
Pathogenic Bacteria ◽  
Antibacterial Agents ◽  
Antimicrobial Properties ◽  
Binding Potential ◽  
Antibacterial Drug ◽  
Next Generation ◽  
Mechanism Of Reaction ◽  
High Level ◽  
Membrane Components

Succumbing to Multi-Drug Resistant (MDR) bacteria is a great distress to the recent health care system. Out of the several attempts that have been made to kill MDR pathogens, a few gained short-lived success. The failures, of the discovered or innovated antimicrobials, were mostly due to their high level of toxicity to hosts and the phenomenal rate of developing resistance by the pathogens against the new arsenal. Recently, a few quantum dots were tested against the pathogenic bacteria and therefore, justified for potential stockpiling of next-generation antibacterial agents. The key players for antimicrobial properties of quantum dots are considered to be Reactive Oxygen Species (ROS). The mechanism of reaction between bacteria and quantum dots needs to be better understood. They are generally targeted towards the cell wall and membrane components as lipoteichoic acid and phosphatidyl glycerol of bacteria have been documented here. In this paper, we have attempted to simulate ZnS quantum dots and have analysed their mechanism of reaction as well as binding potential to the above bacterial membrane components using CDOCKER. Results have shown a high level of antibacterial activity towards several pathogenic bacteria which specify their potentiality for future generation antibacterial drug development.

Sign in / Sign up

Export Citation Format

Share Document