First-month variations in total iodine content of human breast milks

1986 ◽  
Vol 13 (1) ◽  
pp. 81-85 ◽  
Author(s):  
Nicole Etling ◽  
Ezio Padovani ◽  
Françoise Fouque ◽  
Luciano Tato
Keyword(s):  
Iodine Content ◽  
Human Breast ◽  
Total Iodine

DIE ZUSAMMENSETZUNG DER JODHALTIGEN VERBINDUNGEN UND IHRE BEZIEHUNG ZUM JODUMSATZ IN EUTHYREOTEN STRUMEN

1962 ◽  
Vol 41 (4) ◽  
pp. 584-594 ◽  
Author(s):  
Dankwart Reinwein ◽  
Erich Klein
Keyword(s):  
Column Chromatography ◽  
Iodine Content ◽  
High Plasma ◽  
Secretion Rate ◽  
Total Iodine ◽  
Iodine Compound ◽  
Hormonal Secretion ◽  
Carrier Free ◽  
Iodine Metabolism ◽  
Diffuse Goiter

ABSTRACT The iodine metabolism was investigated in 29 patients with euthyroid non-endemic diffuse goiter. 1 to 14 days before thyroidectomy the patients received carrier-free 131I. The chemical iodine fractions (PBI, BEI and iodide) of the thyroid and the labelled iodine compound were analyzed by means of paper- and column chromatography. In one gland the total iodine content varied only by ± 19.6% of the average, the relative shares of PBI, BEI and iodide as well as that of the iodoamino acids being equal. Monoiodotyrosine, diiodotyrosine and thyroxine were found in the thyroid homogenate without hydrolysis. The homogenate after hydrolysis contained more iodotyrosines at the expense of iodothyronines than do normal glands. 17 goiters with normal 131I-uptake showed a high total iodine content (14.2 ± 5.0 mg) whilst 9 goiters with an increased 131I-uptake had low values (3.58 ± 0.6 mg). The opposite was found for the relative shares of BEI with the chromatographically isolated iodothyronines thyroxine, triiodothyronine and an unidentified iodine compound. Goiters with »high plasma PB131I« were characterized by a faster transfer of 131I into the more heavily iodinated compounds than is found in glands with a normal hormonal secretion rate. The highest values for the iodothyronines were found in goiters with increased 131I-uptake together with a high hormonal secretion rate. From this study it appears that the changes in the iodine-poor glands are due to a defective exo- or endogenous iodine supply. The observed alterations in iodine-rich glands are probably induced by a faulty iodine utilization characterized by an incomplete iodotyrosyl-coupling defect.

scholarly journals Iodine and iodothyronine content in human neonate thyroid gland

2002 ◽  
Vol 54 (3-4) ◽  
pp. 69-74 ◽  
Author(s):  
Svetlana Savin-Zegarac ◽  
Dubravka Cvejic ◽  
Olgica Nedic ◽  
R. Radosavljevic ◽  
Ivana Petrovic
Keyword(s):  
Thyroid Gland ◽  
Gestational Age ◽  
Thyroid Tissue ◽  
Iodine Content ◽  
Postnatal Life ◽  
Total Iodine ◽  
Mean Values ◽  
Human Neonate ◽  
The Mean ◽  
Human Neonates

A few years after the iodine content of salt in Serbia was increased from 7 to 15 mg/kg NaCI, iodine, thyroxine (T4) and triiodothyronine (T3) concentrations were measured in thyroid tissue obtained at autopsy from 21 human neonates who died within 30 days after birth. The thyroidal iodine as well as T4 and T3 content per gland in?creased progressively with gestational age of human neonates (r = 0.73, 0.70 and 0.67 respectively, p < 0.001). In seven newborns (gestational age 36 to 41 weeks) the mean values for total iodine, T4 and T3 per gland were 109.1 ?g, 52.2 ?g and 4.4 ?g respectively. The results of iodine and iodothyroninc content found in neonatal thyroid gland, particularly at the end of gestation and a few days of postnatal life, indicates that the iodine supply was satisfactory.

The total Iodine and Iodate-iodine content of sea-water

1960 ◽  
Vol 7 (1) ◽  
pp. 24-34 ◽  
Author(s):  
Richard A. Barkley ◽  
Thomas G. Thompson
Keyword(s):  
Sea Water ◽  
Iodine Content ◽  
Total Iodine

scholarly journals Iodine content in consumer hen eggs

2012 ◽  
Vol 51 (No. 3) ◽  
pp. 93-100 ◽  
Author(s):  
J. Travnicek ◽  
V. Kroupova ◽  
I. Herzig ◽  
J. Kursa
Keyword(s):  
Czech Republic ◽  
Correlation Coefficient ◽  
Daily Intake ◽  
Iodine Content ◽  
Egg Yolk ◽  
Human Nutrition ◽  
Total Iodine ◽  
Fresh Matter ◽  
The Czech Republic

This paper presents the latest information about the supply of iodine to meet its requirements in hens of laying type, on the basis of iodine content in egg yolk and about the importance of eggs as an iodine source in human nutrition. The Sandell-Kolthoff method was applied to determine iodine content in the yolk of eggs from 9 large flocks (54 eggs) and 16 small flocks (96 eggs) in 2004, and from 10 large flocks (135 eggs) and 15&nbsp;small flocks (114 eggs) in 2005. Iodine content was also determined in the albumen of 70 eggs. In 2004, the iodine content in the yolk of eggs from large flocks was 1 014.1 &plusmn; 356.6 while in 2005 it amounted to 1 663.8 &plusmn; 1&nbsp;179.7&nbsp;&micro;g/kg fresh matter (P &lt; 0.01); the respective values for the yolk of eggs from small flocks in 2004 and 2005 were 307.1 &plusmn; 255.7 and 519.5 &plusmn; 508.2 &micro;g/kg fresh matter (P &lt; 0.01). Compared to 1996, in 2005, the iodine content in yolk increased by 123.7% in large flocks, and by 19.2% in small flocks. The iodine content in albumen was 16.2&nbsp;&plusmn; 9.7 &micro;g/kg fresh matter, and it accounted for 2.6&ndash;5.0% of the total iodine content in 1 egg. The correlation coefficient between iodine contents in yolk and albumen was r = 0.67. In the Czech Republic, 1 egg from large flocks contains on average 31.2 &micro;g iodine while 1 egg from small flocks contains 10.0 &micro;g. Eggs from large flocks cover 7&ndash;14% and from small flocks 2.2&ndash;4.4% of the daily iodine requirement in adults. Iodine concentrations exceeding 2 500 &micro;g/kg yolk fresh matter in large flocks were measured between week 32 and 60 of the laying cycle and with daily intake of 0.116&ndash;0.132 mg iodine per hen.

Calcium and metabolism of I131 in rats and homogenates of rat thyroid

1961 ◽  
Vol 200 (5) ◽  
pp. 1023-1026 ◽  
Author(s):  
Yaro Ribeiro Gandra ◽  
John G. Coniglio
Keyword(s):  
Thyroid Tissue ◽  
Iodine Content ◽  
In Vitro Studies ◽  
Iodine Uptake ◽  
Total Iodine ◽  
Organic Iodine ◽  
Free Iodine ◽  
Inorganic Iodine ◽  
Rat Thyroid

The goitrogenic effect of calcium was studied by the use of I131 in intact rats and in rat thyroid slices. Rats receiving excess dietary calcium had larger thyroids than controls. Enlargement of the thyroid was accompanied by increased content of inorganic iodine and decreased content of organic iodine. In vitro studies showed that thyroid enlargement was associated with greater total iodine uptake. Addition of calcium to the incubation medium decreased the total iodine uptake of thyroid slices. The reduction occurred as a consequence of interference with the conversion of inorganic iodine to organic iodine. No decrease in inorganic iodine content was observed. The ratios of bound iodine to free iodine were constantly smaller in the thyroid groups receiving calcium supplement. The results of the in vitro studies suggest that calcium interference is due, at least in part, to a direct effect on thyroid tissue.

IODINATED PARTICLES IN THE RAT THYROID I. A RAPID SEPARATION METHOD

1971 ◽  
Vol 68 (2) ◽  
pp. 367-376 ◽  
Author(s):  
C. Simon ◽  
J. Dang ◽  
R. Miquelis ◽  
P. Bastiani
Keyword(s):  
Sucrose Solution ◽  
Maximum Yield ◽  
Iodine Content ◽  
Isotopic Equilibrium ◽  
Rapid Separation ◽  
Total Iodine ◽  
Ficoll Gradient ◽  
Group 5 ◽  
Secondary Lysosomes ◽  
Rat Thyroid

ABSTRACT In a first step, the quantitative preparation of the whole population of iodinated particles was reinvestigated in thyroids obtained from rats maintained in an isotopic equilibrium with 125I. The maximum yield in the iodinated particles was obtained for a 0.15 m sucrose solution in 0.1 m Tris-HCl buffer pH 7. This yield was 3.5 % and 1.7 % of the total iodine content of the thyroid for rats adapted to receive 50 (group 50) and 5 μg (group 5) of iodine daily respectively. The iodinated particles of group 50 were found to be more sensitive to pH variations than those of group 5. In a second step, a rapid method was developed to separate the whole population of iodinated particles into physiological populations (tentatively colloid droplets and secondary lysosomes). By centrifuging onto a discontinuous Ficoll gradient, three distinct iodine peaks were regularly obtained for rats of group 5 and 50 and also for other rats receiving a diet rich in iodine. For group 50, the iodine pools (127I) as measured by isotopic equilibrium were found to represent about 16% (peak 1), 25 % (peak 2) and 59 % (peak 3) of the total particulate iodine content of the gland. The possible nature of these three populations of iodinated particles is discussed.

scholarly journals A New Analytical Method for Measuring Total Iodine Content in Fish for the Standard Tables of Food Composition in Japan

2017 ◽  
Vol 64 (6) ◽  
pp. 312-318 ◽  
Author(s):  
Daisuke Miyake ◽  
Akiyo Bogaki ◽  
Chiharu Tokuda ◽  
Tomoji Igarashi ◽  
Akemi Yasui
Keyword(s):  
Analytical Method ◽  
Iodine Content ◽  
Food Composition ◽  
Total Iodine

scholarly journals Iodine concentration and content measured by dual-source computed tomography are correlated to thyroid hormone levels in euthyroid  patients: a cross-sectional study in China

2019 ◽  
Author(s):  
ZhengTeng Li ◽  
Rui Zhai ◽  
HongMei Liu ◽  
Min Wang ◽  
Dongmei Pan
Keyword(s):  
Thyroid Hormone ◽  
Thyroid Function ◽  
Thyroid Tissue ◽  
Iodine Content ◽  
Iodine Concentration ◽  
Dual Energy ◽  
Dual Energy Ct ◽  
Total Iodine ◽  
Cross Sectional ◽  
The Mean

Abstract Background: The aim of this study was to investigate the correlation of the dual energy CT measured iodine concentration and total iodine content with blood measured thyroid parameters. Methods: 43 patients with normal thyroid function at our hospital from August 2017 to October 2019 were included in this retrospective study. Dual energy CT was used to scan the neck of thyroid patients. The mean iodine concentration and thyroid tissue volume were measured to calculate the total iodine content of the thyroid. Relevant tests of triiodothyronine (FT3), total triiodothyronine (TT3), total thyroxine (TT4), free thyroxine (FT4), and thyroid hormone (TSH) were conducted. The correlation of the thyroid mean iodine concentration and total iodine content with blood-measured thyroid function was analysed. Result: The total iodine content in the thyroid was positively correlated with FT3 but negatively correlated with TSH. The mean iodine concentration of the thyroid was positively correlated with both FT3 and TT3. Conclusion : The thyroid iodine content measured by dual energy CT can be used to determine the human iodine nutritional status and evaluate thyroid function, which will facilitate the diagnosis and treatment of thyroid diseases.

scholarly journals Iodine concentration and content measured by dual-source computed tomography are correlated to thyroid hormone levels in euthyroid patients

2019 ◽  
Author(s):  
ZhengTeng Li ◽  
Rui Zhai ◽  
HongMei Liu ◽  
Dongmei Pan
Keyword(s):  
Thyroid Hormone ◽  
Thyroid Function ◽  
Thyroid Tissue ◽  
Iodine Content ◽  
Iodine Concentration ◽  
Dual Energy ◽  
Dual Energy Ct ◽  
Total Iodine ◽  
Normal Thyroid Function ◽  
The Mean

Abstract Background: The aim of this study was to investigate the correlation of the dual energy CT measured iodine concentration and total iodine content with blood measured thyroid parameters. Methods: 43 patients with normal thyroid function at our hospital from August 2017 to October 2019 were included in this retrospective study. Dual energy CT was used to scan the neck of thyroid patients. The mean iodine concentration and thyroid tissue volume were measured to calculate the total iodine content of the thyroid. Relevant tests of triiodothyronine (FT3), total triiodothyronine (TT3), total thyroxine (TT4), free thyroxine (FT4), and thyroid hormone (TSH) were conducted. The correlation of the thyroid mean iodine concentration and total iodine content with blood-measured thyroid function was analysed. Result: The total iodine content in the thyroid was positively correlated with FT3 but negatively correlated with TSH. The mean iodine concentration of the thyroid was positively correlated with both FT3 and TT3. Conclusion: The thyroid iodine content measured by dual energy CT can be used to determine the human iodine nutritional status and evaluate thyroid function, which will facilitate the diagnosis and treatment of thyroid diseases.

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