Reconstruction Algorithms and Their Influence in Emphysema CT Measurements

2010 ◽  
Vol 17 (5) ◽  
pp. 674 ◽  
Author(s):  
Bruno Hochhegger ◽  
Klaus L. Irion ◽  
Edson Marchiori ◽  
José S. Moreira
Author(s):  
Santosh Bhattacharyya

Three dimensional microscopic structures play an important role in the understanding of various biological and physiological phenomena. Structural details of neurons, such as the density, caliber and volumes of dendrites, are important in understanding physiological and pathological functioning of nervous systems. Even so, many of the widely used stains in biology and neurophysiology are absorbing stains, such as horseradish peroxidase (HRP), and yet most of the iterative, constrained 3D optical image reconstruction research has concentrated on fluorescence microscopy. It is clear that iterative, constrained 3D image reconstruction methodologies are needed for transmitted light brightfield (TLB) imaging as well. One of the difficulties in doing so, in the past, has been in determining the point spread function of the system.We have been developing several variations of iterative, constrained image reconstruction algorithms for TLB imaging. Some of our early testing with one of them was reported previously. These algorithms are based on a linearized model of TLB imaging.


2019 ◽  
Author(s):  
T Mann ◽  
BJ Krause ◽  
A Hawlitschka ◽  
J Stenzel ◽  
T Lindner ◽  
...  

Author(s):  
Wenbing Yun ◽  
Steve Wang ◽  
David Scott ◽  
Kenneth W. Nill ◽  
Waleed S. Haddad

Abstract A high-resolution table-sized x-ray nanotomography (XRMT) tool has been constructed that shows the promise of nondestructively imaging the internal structure of a full IC stack with a spatial resolution better than 100 nm. Such a tool can be used to detect, localize, and characterize buried defects in the IC. By collecting a set of X-ray projections through the full IC (which may include tens of micrometers of silicon substrate and several layers of Cu interconnects) and applying tomographic reconstruction algorithms to these projections, a 3D volumetric reconstruction can be obtained, and analyzed for defects using 3D visualization software. XRMT is a powerful technique that will find use in failure analysis and IC process development, and may facilitate or supplant investigations using SEM, TEM, and FIB tools, which generally require destructive sample preparation and a vacuum environment.


2021 ◽  
Vol 5 (3) ◽  
pp. 83
Author(s):  
Bilgi Görkem Yazgaç ◽  
Mürvet Kırcı

In this paper, we propose a fractional differential equation (FDE)-based approach for the estimation of instantaneous frequencies for windowed signals as a part of signal reconstruction. This approach is based on modeling bandpass filter results around the peaks of a windowed signal as fractional differential equations and linking differ-integrator parameters, thereby determining the long-range dependence on estimated instantaneous frequencies. We investigated the performance of the proposed approach with two evaluation measures and compared it to a benchmark noniterative signal reconstruction method (SPSI). The comparison was provided with different overlap parameters to investigate the performance of the proposed model concerning resolution. An additional comparison was provided by applying the proposed method and benchmark method outputs to iterative signal reconstruction algorithms. The proposed FDE method received better evaluation results in high resolution for the noniterative case and comparable results with SPSI with an increasing iteration number of iterative methods, regardless of the overlap parameter.


Diagnostics ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1209
Author(s):  
Gabriel Keller ◽  
Simon Götz ◽  
Mareen Sarah Kraus ◽  
Leonard Grünwald ◽  
Fabian Springer ◽  
...  

This study analyzed the radiation exposure of a new ultra-low dose (ULD) protocol compared to a high-quality (HQ) protocol for CT-torsion measurement of the lower limb. The analyzed patients (n = 60) were examined in the period March to October 2019. In total, 30 consecutive patients were examined with the HQ and 30 consecutive patients with the new ULD protocol comprising automatic tube voltage selection, automatic exposure control, and iterative image reconstruction algorithms. Radiation dose parameters as well as the contrast-to-noise ratio (CNR) and diagnostic confidence (DC; rated by two radiologists) were analyzed and potential predictor variables, such as body mass index and body volume, were assessed. The new ULD protocol resulted in significantly lower radiation dose parameters, with a reduction of the median total dose equivalent to 0.17 mSv in the ULD protocol compared to 4.37 mSv in the HQ protocol (p < 0.001). Both groups showed no significant differences in regard to other parameters (p = 0.344–0.923). CNR was 12.2% lower using the new ULD protocol (p = 0.033). DC was rated best by both readers in every HQ CT and in every ULD CT. The new ULD protocol for CT-torsion measurement of the lower limb resulted in a 96% decrease of radiation exposure down to the level of a single pelvic radiograph while maintaining good image quality.


2021 ◽  
Vol 13 (14) ◽  
pp. 2838
Author(s):  
Yaping Mo ◽  
Yongming Xu ◽  
Huijuan Chen ◽  
Shanyou Zhu

Land surface temperature (LST) is an important environmental parameter in climate change, urban heat islands, drought, public health, and other fields. Thermal infrared (TIR) remote sensing is the main method used to obtain LST information over large spatial scales. However, cloud cover results in many data gaps in remotely sensed LST datasets, greatly limiting their practical applications. Many studies have sought to fill these data gaps and reconstruct cloud-free LST datasets over the last few decades. This paper reviews the progress of LST reconstruction research. A bibliometric analysis is conducted to provide a brief overview of the papers published in this field. The existing reconstruction algorithms can be grouped into five categories: spatial gap-filling methods, temporal gap-filling methods, spatiotemporal gap-filling methods, multi-source fusion-based gap-filling methods, and surface energy balance-based gap-filling methods. The principles, advantages, and limitations of these methods are described and discussed. The applications of these methods are also outlined. In addition, the validation of filled LST values’ cloudy pixels is an important concern in LST reconstruction. The different validation methods applied for reconstructed LST datasets are also reviewed herein. Finally, prospects for future developments in LST reconstruction are provided.


2020 ◽  
Vol 28 (6) ◽  
pp. 829-847
Author(s):  
Hua Huang ◽  
Chengwu Lu ◽  
Lingli Zhang ◽  
Weiwei Wang

AbstractThe projection data obtained using the computed tomography (CT) technique are often incomplete and inconsistent owing to the radiation exposure and practical environment of the CT process, which may lead to a few-view reconstruction problem. Reconstructing an object from few projection views is often an ill-posed inverse problem. To solve such problems, regularization is an effective technique, in which the ill-posed problem is approximated considering a family of neighboring well-posed problems. In this study, we considered the {\ell_{1/2}} regularization to solve such ill-posed problems. Subsequently, the half thresholding algorithm was employed to solve the {\ell_{1/2}} regularization-based problem. The convergence analysis of the proposed method was performed, and the error bound between the reference image and reconstructed image was clarified. Finally, the stability of the proposed method was analyzed. The result of numerical experiments demonstrated that the proposed method can outperform the classical reconstruction algorithms in terms of noise suppression and preserving the details of the reconstructed image.


2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Johan Economou Lundeberg ◽  
Jenny Oddstig ◽  
Ulrika Bitzén ◽  
Elin Trägårdh

Abstract Background Lung cancer is one of the most common cancers in the world. Early detection and correct staging are fundamental for treatment and prognosis. Positron emission tomography with computed tomography (PET/CT) is recommended clinically. Silicon (Si) photomultiplier (PM)-based PET technology and new reconstruction algorithms are hoped to increase the detection of small lesions and enable earlier detection of pathologies including metastatic spread. The aim of this study was to compare the diagnostic performance of a SiPM-based PET/CT (including a new block-sequential regularization expectation maximization (BSREM) reconstruction algorithm) with a conventional PM-based PET/CT including a conventional ordered subset expectation maximization (OSEM) reconstruction algorithm. The focus was patients admitted for 18F-fluorodeoxyglucose (FDG) PET/CT for initial diagnosis and staging of suspected lung cancer. Patients were scanned on both a SiPM-based PET/CT (Discovery MI; GE Healthcare, Milwaukee, MI, USA) and a PM-based PET/CT (Discovery 690; GE Healthcare, Milwaukee, MI, USA). Standardized uptake values (SUV) and image interpretation were compared between the two systems. Image interpretations were further compared with histopathology when available. Results Seventeen patients referred for suspected lung cancer were included in our single injection, dual imaging study. No statically significant differences in SUVmax of suspected malignant primary tumours were found between the two PET/CT systems. SUVmax in suspected malignant intrathoracic lymph nodes was 10% higher on the SiPM-based system (p = 0.026). Good consistency (14/17 cases) between the PET/CT systems were found when comparing simplified TNM staging. The available histology results did not find any obvious differences between the systems. Conclusion In a clinical setting, the new SiPM-based PET/CT system with a new BSREM reconstruction algorithm provided a higher SUVmax for suspected lymph node metastases compared to the PM-based system. However, no improvement in lung cancer detection was seen.


Micromachines ◽  
2021 ◽  
Vol 12 (2) ◽  
pp. 164
Author(s):  
Dongxu Wu ◽  
Fusheng Liang ◽  
Chengwei Kang ◽  
Fengzhou Fang

Optical interferometry plays an important role in the topographical surface measurement and characterization in precision/ultra-precision manufacturing. An appropriate surface reconstruction algorithm is essential in obtaining accurate topography information from the digitized interferograms. However, the performance of a surface reconstruction algorithm in interferometric measurements is influenced by environmental disturbances and system noise. This paper presents a comparative analysis of three algorithms commonly used for coherence envelope detection in vertical scanning interferometry, including the centroid method, fast Fourier transform (FFT), and Hilbert transform (HT). Numerical analysis and experimental studies were carried out to evaluate the performance of different envelope detection algorithms in terms of measurement accuracy, speed, and noise resistance. Step height standards were measured using a developed interferometer and the step profiles were reconstructed by different algorithms. The results show that the centroid method has a higher measurement speed than the FFT and HT methods, but it can only provide acceptable measurement accuracy at a low noise level. The FFT and HT methods outperform the centroid method in terms of noise immunity and measurement accuracy. Even if the FFT and HT methods provide similar measurement accuracy, the HT method has a superior measurement speed compared to the FFT method.


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