scholarly journals Beneficial effects of a personalized home-based training among patients suffering from the Marfan syndrome

2022 ◽  
Vol 14 (1) ◽  
pp. 103-104
Author(s):  
S. Jouini ◽  
G. Jondeau ◽  
O. Milleron ◽  
L. Eliahou ◽  
D. Vitiello
Keyword(s):  
Marfan Syndrome ◽  
Beneficial Effects ◽  
Home Based

scholarly journals Understanding and Addressing the Role of Coping in Palliative Care for Patients With Advanced Cancer

2020 ◽  
Vol 38 (9) ◽  
pp. 915-925 ◽  
Author(s):  
Joseph A. Greer ◽  
Allison J. Applebaum ◽  
Juliet C. Jacobsen ◽  
Jennifer S. Temel ◽  
Vicki A. Jackson
Keyword(s):  
Palliative Care ◽  
Coping Strategies ◽  
Advanced Cancer ◽  
Physical Symptoms ◽  
Early Palliative Care ◽  
Beneficial Effects ◽  
Symptoms Of Depression ◽  
Home Based ◽  
Oncology Care

Advanced cancer, with its considerable physical symptoms and psychosocial burdens, represents an existential threat and major stressor to patients and their caregivers. In response to such stress, patients and their caregivers use a variety of strategies to manage the disease and related symptoms, such as problem-focused, emotion-focused, meaning-focused, and spiritual/religious coping. The use of such coping strategies is associated with multiple outcomes, including quality of life, symptoms of depression and anxiety, illness understanding, and end-of-life care. Accumulating data demonstrate that early palliative care, integrated with oncology care, not only improves these key outcomes but also enhances coping in patients with advanced cancer. In addition, trials of home-based palliative care interventions have shown promise for improving the ways that patients and family caregivers cope together and manage problems as a dyad. In this article, we describe the nature and correlates of coping in this population, highlight the role of palliative care to promote effective coping strategies in patients and caregivers, and review evidence supporting the beneficial effects of palliative care on patient coping as well as the mechanisms by which improved coping is associated with better outcomes. We conclude with a discussion of the limitations of the state of science, future directions, and best practices on the basis of available evidence.

scholarly journals Multicomponent interventions against frailty

2021 ◽  
pp. 1-2
Author(s):  
D. Azzolino ◽  
M. Cesari
Keyword(s):  
Physical Activity ◽  
Dietary Habits ◽  
Functional Decline ◽  
Education Programs ◽  
Beneficial Effects ◽  
Age Related ◽  
Home Based ◽  
Related Risk ◽  
Nutrition And Physical Activity ◽  
Multicomponent Interventions

The prevention and management of frailty imply the delay of functional decline. Recently, there has been a growing interest in the adoption of multicomponent interventions, usually incorporating nutrition and physical activity strategies targeted to age-related risk conditions like frailty and sarcopenia (1). The protocol published by Low et al. (2) is based on a 4-month program including a combination of group exercise (1 hour, once a week) and the prescription of home-based exercises, together with group-based educational seminars (i.e., six sessions) on nutrition. As outlined in the manuscript, the beneficial effects of nutrition and physical activity as strategies to prevent and manage frailty are well established. However, a challenge in delivering nutritional education programs to older people is represented by the difficulty in motivating persons at acquiring new dietary habits because of multiple reasons (e.g., sociocultural, economic, or clinical issues). The personalization of the interventions may represent an effective strategy to promote these changes (3).

scholarly journals A rapid review of home-based activities that can promote mental wellness during the COVID-19 pandemic

PLoS ONE ◽  
2020 ◽  
Vol 15 (12) ◽  
pp. e0243125
Author(s):  
Joseph H. Puyat ◽  
Haroon Ahmad ◽  
Ana Michelle Avina-Galindo ◽  
Arminee Kazanjian ◽  
Aanchel Gupta ◽  
...  
Keyword(s):  
Mental Health ◽  
Mental Health Professionals ◽  
Risk Of Bias ◽  
Rapid Review ◽  
Review Author ◽  
Beneficial Effects ◽  
Home Based ◽  
Mental Wellness ◽  
The Impact ◽  
At Home

Background During the COVID-19 pandemic, public health measures such as isolation, quarantine, and social distancing are needed. Some of these measures can adversely affect mental health. Activities that can be performed at home may mitigate these consequences and improve overall mental well-being. In this study, home-based activities that have potential beneficial effects on mental health were examined. Methods A rapid review was conducted based on a search of the following databases: MEDLINE, EMBASE, CINAHL, PyscINFO, Global Health, epistemonikos.org, covid19reviews.org, and eppi.ioe.ac.uk/covid19_map_v13.html. Eligible studies include randomized controlled trials and non-randomized studies published between 1/1/2000 and 28/05/2020 and that examined the impact of various activities on mental health outcomes in low-resource settings and contexts that lead to social isolation. Studies of activities that require mental health professionals or that could not be done at home were excluded. Two review authors performed title/abstract screening. At the full-text review stage, 25% of the potentially eligible studies were reviewed in full by two review authors; the rest were reviewed by one review author. Risk of bias assessment and data extraction were performed by one review author and checked by a second review author. The main outcome assessed was change or differences in mental health as expressed in Cohen’s d; analysis was conducted following the synthesis without meta-analysis guidelines (SWiM). PROSPERO registration: CRD42020186082. Results Of 1,236 unique records identified, 160 were reviewed in full, resulting in 16 included studies. The included studies reported on the beneficial effects of exercise, yoga, progressive muscle relaxation, and listening to relaxing music. One study reported on the association between solitary religious activities and post traumatic stress disorder symptoms. While most of the included studies examined activities in group settings, particularly among individuals in prisons, the activities were described as something that can be performed at home and alone. All included studies were assessed to be at risk of bias in one or more of the bias domains examined. Conclusions There is some evidence that certain home-based activities can promote mental wellness during the COVID-19 pandemic. Guidelines are needed to help optimize benefits while minimizing potential risks when performing these activities.

scholarly journals The Potential Beneficial Effects of Resveratrol on Cardiovascular Complications in Marfan Syndrome Patients–Insights from Rodent-Based Animal Studies

2019 ◽  
Vol 20 (5) ◽  
pp. 1122 ◽  
Author(s):  
Mitzi van Andel ◽  
Maarten Groenink ◽  
Aeilko Zwinderman ◽  
Barbara Mulder ◽  
Vivian de Waard
Keyword(s):  
Oxidative Stress ◽  
Extracellular Matrix ◽  
Smooth Muscle ◽  
Aortic Aneurysm ◽  
Smooth Muscle Cell ◽  
Marfan Syndrome ◽  
Muscle Cell ◽  
Treatment Strategy ◽  
Beneficial Effects ◽  
Aneurysm Formation

Marfan syndrome (MFS) patients are at risk for cardiovascular disease. In particular, for aortic aneurysm formation, which ultimately can result in a life-threatening aortic dissection or rupture. Over the years, research into a sufficient pharmacological treatment option against aortopathy has expanded, mostly due to the development of rodent disease models for aneurysm formation and dissections. Unfortunately, no optimal treatment strategy has yet been identified for MFS. The biologically-potent polyphenol resveratrol (RES), that occurs in nuts, plants, and the skin of grapes, was shown to have a positive effect on aortic repair in various rodent aneurysm models. RES demonstrated to affect aortic integrity and aortic dilatation. The beneficial processes relevant for MFS included the improvement of endothelial dysfunction, extracellular matrix degradation, and smooth muscle cell death. For the wide range of beneficial effects on these mechanisms, evidence was found for the following involved pathways; alleviating oxidative stress (change in eNOS/iNOS balance and decrease in NOX4), reducing protease activity to preserve the extracellular matrix (decrease in MMP2), and improving smooth muscle cell survival affecting aortic aging (changing the miR21/miR29 balance). Besides aortic features, MFS patients may also suffer from manifestations concerning the heart, such as mitral valve prolapse and left ventricular impairment, where evidence from rodent models shows that RES may aid in promoting cardiomyocyte survival directly (SIRT1 activation) or by reducing oxidative stress (increasing superoxide dismutase) and increasing autophagy (AMPK activation). This overview discusses recent RES studies in animal models of aortic aneurysm formation and heart failure, where different advantageous effects have been reported that may collectively improve the aortic and cardiac pathology in patients with MFS. Therefore, a clinical study with RES in MFS patients seems justified, to validate RES effectiveness, and to judge its suitability as potential new treatment strategy.

128 Homemade Pet Diets—What Are the Key Supplement Considerations?

2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 65-66
Author(s):  
Cheryl L Morris
Keyword(s):  
Oxidative Stress ◽  
Social Media ◽  
Research Council ◽  
National Research Council ◽  
Health Impacts ◽  
Nutrient Requirements ◽  
Beneficial Effects ◽  
Balanced Diet ◽  
Home Based ◽  
Copper Zinc

Abstract Interest in preparing pet foods at home has continued to build momentum over the last decade. Websites, blogs, and social media groups praise the benefits of feeding raw and home-prepared diets. Consistent research has demonstrated the beneficial effects of raw diets on macronutrient digestibility (primarily fat and protein); however, research is lacking on overall health impacts. While it is important to acknowledge the lack of substantial research, owner choice and compliance also should be considered. With well-established nutrient requirements for dogs and cats available through AAFCO and the National Research Council (NRC), it is relatively uncomplicated to meet requirements when typical processing methods are not required (extrusion or canning). Although it is not complicated to meet the requirements with home-based fresh or lightly cooked ingredients, care must be taken to properly ensure that vitamin and mineral requirements are met. In review of over 100 homemade diets submitted for evaluation, 0% met all vitamin and mineral requirements for dogs or cats. All diets were supplemented with some form of calcium. Approximately 25% of submitted diets utilized bones as the source of calcium. Bones can be problematic depending on type, particularly for digestion, broken pieces that can cause intestinal blockages, and broken teeth. None of the diets were properly balanced for copper, zinc and iron. It is likely, this triad of minerals has been overlooked in diet formulations. It is critical to note that improper balance of these minerals could play a significant role in oxidative stress and aging. Iodine is typically met through additions of kelp; however, variations in quality can result in over or under-supplementation having detrimental effects on the thyroid. Vitamins E and D also are often under-supplemented in these diets. Educating owners on nutrient requirements and ratios, and providing proper supplementation, can assure a quality and balanced diet.

scholarly journals Beneficial effects of home-based cardiac rehabilitation on metabolic profiles in coronary heart-disease patients

2016 ◽  
Vol 32 (5) ◽  
pp. 267-275 ◽  
Author(s):  
Jing-Ting Chen ◽  
Tsung-Hsien Lin ◽  
Wen-Chol Voon ◽  
Wen-Ter Lai ◽  
Mao-Hsiung Huang ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Cardiac Rehabilitation ◽  
Metabolic Profiles ◽  
Beneficial Effects ◽  
Home Based

An evidence-based hypothesis for beneficial effects of telmisartan on Marfan syndrome

2012 ◽  
Vol 158 (1) ◽  
pp. 101-102 ◽  
Author(s):  
Hisato Takagi ◽  
Hirotaka Yamamoto ◽  
Kotaro Iwata ◽  
Shin-nosuke Goto ◽  
Takuya Umemoto
Keyword(s):  
Marfan Syndrome ◽  
Evidence Based ◽  
Beneficial Effects

Sport Therapy for Hypertension: Why, how, and how Much?

Angiology ◽  
2008 ◽  
Vol 60 (2) ◽  
pp. 207-216 ◽  
Author(s):  
Fabio Manfredini ◽  
Anna M. Malagoni ◽  
Simona Mandini ◽  
Benedetta Boari ◽  
Michele Felisatti ◽  
...  
Keyword(s):  
Genetic Factors ◽  
Hypotensive Effect ◽  
Moderate Intensity ◽  
Pharmacologic Therapy ◽  
Lifestyle Modifications ◽  
Parental History ◽  
Beneficial Effects ◽  
Home Based ◽  
Reduce Risk ◽  
Intensity Training

Exercise may prevent or reduce the effects of metabolic and cardiovascular diseases, including arterial hypertension. Both acute and chronic exercise, alone or combined with lifestyle modifications, decrease blood pressure and avoid or reduce the need for pharmacologic therapy in patients with hypertension. The hypotensive effect of exercise is observed in a large percentage of subjects, with differences due to age, sex, race, health conditions, parental history, and genetic factors. Exercise regulates autonomic nervous system activity, increases shear stress, improves nitric oxide production in endothelial cells and its bioavailability for vascular smooth muscle, up-regulates antioxidant enzymes. Endurance training is primarily effective, and resistance training can be combined with it. Low-to-moderate intensity training in sedentary patients with hypertension is necessary, and tailored programs make exercise safe and effective also in special populations. Supervised or home-based exercise programs allow a nonpharmacological reduction of hypertension and reduce risk factors, with possible beneficial effects on cardiovascular morbidity.

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