Lack of Association of Interleukin-1 Gene Cluster Polymorphisms with Angiographically Documented Coronary Artery Disease: Demonstration of Association with Hypertension in the Polish Population

2011 ◽  
Author(s):  
Jarosław Gorący ◽  
Iwona Gorący ◽  
Krzysztof Safranow ◽  
Olga Taryma ◽  
Grażyna Adler ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Gene Cluster ◽  
Interleukin 1 ◽  
Polish Population ◽  
Artery Disease ◽  
Documented Coronary Artery Disease

scholarly journals Relationship between rs4674344 CYP27A1 gene polymorphism and coronary artery disease in Polish population

2019 ◽  
Author(s):  
Joanna Iwanicka ◽  
Tomasz Iwanicki ◽  
Anna Balcerzyk ◽  
Paweł Niemiec ◽  
Tomasz Nowak ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Gene Polymorphism ◽  
Polish Population ◽  
Artery Disease

scholarly journals Relationship between rs854560PON1Gene Polymorphism and Tobacco Smoking with Coronary Artery Disease

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Joanna Iwanicka ◽  
Tomasz Iwanicki ◽  
Paweł Niemiec ◽  
Tomasz Nowak ◽  
Jolanta Krauze ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Cigarette Smoking ◽  
Relative Increase ◽  
Paraoxonase 1 ◽  
High Density Lipoproteins ◽  
Polish Population ◽  
Premature Cad ◽  
Traditional Risk Factors ◽  
Artery Disease

Paraoxonase-1 (PON1) is the antioxidant marker of high-density lipoproteins protecting against atherosclerosis and coronary artery disease (CAD) phenotype. The purpose of the present study was to determine whether thePON1gene rs854560 polymorphism (163T>A) is associated with CAD in Polish population. rs854560 was genotyped in 494 subjects: 248 patients with premature CAD and 246 blood donors as a control. We found that the risk of CAD was significantly higher in TT homozygotes than in A allele carriers (OR = 1.87,p=0.041). The synergistic effect between the TT genotype and cigarette smoking was observed (SIM = 9.81; SI = 14.70). The relative increase in risk from interaction between factors was over 37 (RERI = 36.13). ThePON1polymorphism did not modulate the risk of CAD in response to exposure to other traditional risk factors. In conclusion, the rs854560 polymorphism may modulate the risk of CAD in response to cigarette smoking in Polish population. Carriers of TT genotype seem to be particularly at risk of CAD, when exposed to cigarette smoking.

Behaviour of vitamin e, a and c in patients with documented coronary artery disease

1993 ◽  
Vol 70 ◽  
pp. S143
Author(s):  
C Censi ◽  
S Basili ◽  
R Leo ◽  
E Vezza ◽  
D Pratico ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Vitamin E ◽  
Artery Disease ◽  
Documented Coronary Artery Disease
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