Duplex Metal Co-Doped Carbon Quantum Dots-Based Drug Delivery System with Intelligent Adjustable Size as Adjuvant for Synergistic Cancer Therapy

Carbon ◽  
2021 ◽  
Author(s):  
Chuyi Han ◽  
Xianming Zhang ◽  
Fan Wang ◽  
Qinghua Yu ◽  
Feng Chen ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Quantum Dots ◽  
Cancer Therapy ◽  
Drug Delivery System ◽  
Delivery System ◽  
Carbon Quantum Dots ◽  
Co Doped

scholarly journals Carbon quantum dots-stabilized Pickering emulsion to prepare NIR light-responsive PLGA drug delivery system

2020 ◽  
Vol 23 ◽  
pp. 100951 ◽  
Author(s):  
Tongchang Zhou ◽  
Zheng Huang ◽  
Feng Wan ◽  
Yi Sun
Keyword(s):  
Drug Delivery ◽  
Quantum Dots ◽  
Drug Delivery System ◽  
Delivery System ◽  
Pickering Emulsion ◽  
Carbon Quantum Dots ◽  
Nir Light

A novel controllable molecularly imprinted drug delivery system based on the photothermal effect of graphene oxide quantum dots

2019 ◽  
Vol 54 (12) ◽  
pp. 9124-9139 ◽  
Author(s):  
Yarong Xu ◽  
Xiaoling Hu ◽  
Ping Guan ◽  
Chunbao Du ◽  
Yuan Tian ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Quantum Dots ◽  
Graphene Oxide ◽  
Drug Delivery System ◽  
Delivery System ◽  
Photothermal Effect ◽  
Molecularly Imprinted ◽  
Graphene Oxide Quantum Dots

Preparation and evaluation of gemcitabin and cisplatin-entrapped Folate-PEGylated liposomes as targeting co-drug delivery system in cancer therapy

2021 ◽  
pp. 102756
Author(s):  
Pooneh Pakdaman Goli ◽  
Maryam Bikhof Torbati ◽  
Kazem Parivar ◽  
Azim Akbarzadeh Khiavi ◽  
Mohammad Yousefi
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Delivery System ◽  
Delivery System ◽  
Pegylated Liposomes ◽  
Preparation And Evaluation

scholarly journals Novel concept of the smart NIR-light–controlled drug release of black phosphorus nanostructure for cancer therapy

2018 ◽  
Vol 115 (3) ◽  
pp. 501-506 ◽  
Author(s):  
Meng Qiu ◽  
Dou Wang ◽  
Weiyuan Liang ◽  
Liping Liu ◽  
Yin Zhang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Release ◽  
Drug Delivery System ◽  
Delivery System ◽  
Near Infrared ◽  
Black Phosphorus ◽  
Deep Penetration ◽  
Nir Light

A biodegradable drug delivery system (DDS) is one the most promising therapeutic strategies for cancer therapy. Here, we propose a unique concept of light activation of black phosphorus (BP) at hydrogel nanostructures for cancer therapy. A photosensitizer converts light into heat that softens and melts drug-loaded hydrogel-based nanostructures. Drug release rates can be accurately controlled by light intensity, exposure duration, BP concentration, and hydrogel composition. Owing to sufficiently deep penetration of near-infrared (NIR) light through tissues, our BP-based system shows high therapeutic efficacy for treatment of s.c. cancers. Importantly, our drug delivery system is completely harmless and degradable in vivo. Together, our work proposes a unique concept for precision cancer therapy by external light excitation to release cancer drugs. If these findings are successfully translated into the clinic, millions of patients with cancer will benefit from our work.

Functionalized halloysite nanotube by chitosan grafting for drug delivery of curcumin to achieve enhanced anticancer efficacy

2016 ◽  
Vol 4 (13) ◽  
pp. 2253-2263 ◽  
Author(s):  
Mingxian Liu ◽  
Yanzhou Chang ◽  
Jing Yang ◽  
Yuanyuan You ◽  
Rui He ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Delivery System ◽  
Delivery System ◽  
Halloysite Nanotube ◽  
Anticancer Efficacy

A new HNTs-based drug delivery system to improve the bioavailability of curcumin for cancer therapy is proposed.

scholarly journals Doxorubicin conjugated carbon dots as a drug delivery system for human breast cancer therapy

2018 ◽  
Vol 51 (5) ◽  
pp. e12488 ◽  
Author(s):  
Tingting Kong ◽  
Liying Hao ◽  
Yuanyuan Wei ◽  
Xiaoxiao Cai ◽  
Bofeng Zhu
Keyword(s):  
Breast Cancer ◽  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Delivery System ◽  
Delivery System ◽  
Carbon Dots ◽  
Human Breast Cancer ◽  
Human Breast ◽  
Breast Cancer Therapy

scholarly journals A pH-Responsive Charge-Reversal Drug Delivery System with Tumor-Specific Drug Release and ROS Generation for Cancer Therapy

2020 ◽  
Vol Volume 15 ◽  
pp. 65-80 ◽  
Author(s):  
Chen Xu ◽  
Rijin Song ◽  
Pei Lu ◽  
Jianchun Chen ◽  
Yongqiang Zhou ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Release ◽  
Drug Delivery System ◽  
Delivery System ◽  
Ros Generation ◽  
Specific Drug ◽  
Ph Responsive ◽  
Charge Reversal

A smart drug-delivery nanosystem based on carboxylated graphene quantum dots for tumor-targeted chemotherapy

Nanomedicine ◽  
2019 ◽  
Vol 14 (15) ◽  
pp. 2011-2025 ◽  
Author(s):  
Zhen Li ◽  
Jialong Fan ◽  
Chunyi Tong ◽  
Hongyan Zhou ◽  
Wenmiao Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Quantum Dots ◽  
Folic Acid ◽  
Ethylene Glycol ◽  
Drug Delivery System ◽  
Delivery System ◽  
Graphene Quantum Dots ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Aim: Constructing a new drug-delivery system using carboxylated graphene quantum dots (cGQDs) for tumor chemotherapy in vivo. Materials & methods: A drug-delivery system was synthesized through a crosslink reaction of cGQDs, NH2-poly(ethylene glycol)-NH2 and folic acid. Results: A drug delivery system of folic acid-poly(ethylene glycol)-cGQDs was successfully constructed with ideal entrapment efficiency (97.5%) and drug-loading capacity (40.1%). Cell image indicated that the nanosystem entered into human cervical cancer cells mainly through macropinocytosis-dependent pathway. In vivo experiments showed the outstanding antitumor ability and low systemic toxicity of this nanodrug-delivery system. Conclusion: The newly developed drug-delivery system provides an important alternative for tumor therapy without causing systemic adverse effects.

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