Fluorinated carbon dots/carboxyl methyl cellulose sodium composite with a temperature-sensitive fluorescence/phosphorescence applicable for anti-counterfeiting marking

Carbon ◽  
2021 ◽  
Author(s):  
Mingsheng Xu ◽  
Chen Dong ◽  
Jiahui Xu ◽  
Sajid ur Rehman ◽  
Qiyang Wang ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Methyl Cellulose ◽  
Temperature Sensitive ◽  
Fluorinated Carbon

scholarly journals The Preparation of Green Fluorescence-Emissioned Carbon Dots/Poly(N-Isopropylacrylamide) Temperature-Sensitive Hydrogels and Research on Their Properties

Polymers ◽  
2019 ◽  
Vol 11 (7) ◽  
pp. 1171 ◽  
Author(s):  
Dan Zhao ◽  
Wenting Ma ◽  
Rong Wang ◽  
Xinzhou Yang ◽  
Jun Li ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Fluorescence Spectra ◽  
Cell Imaging ◽  
Fluorescence Probes ◽  
Excitation Wavelength ◽  
Temperature Sensitive ◽  
Green Fluorescence ◽  
Microscope Imaging ◽  
One Step ◽  
Good Biocompatibility

Fluorescence/temperature-sensitive hydrogels, thanks to their properties in fluorescence and temperature sensitivity, have shown a promising outlook in the fields of drug delivery, cell imaging, etc., and thus become the focus of present research. This paper reports the preparation of green-fluorescence/temperature-sensitive hydrogels through one-step radical polymerization with green fluorescence-emissioned carbon dots as fluorescence probes and N-isopropylacrylamide as a monomer. UV-vis spectra, fluorescence spectra, and fluorescence microscope imaging have been used to characterize the prepared hydrogel, and to study their optical and temperature-sensitive properties. It was discovered that the emission of prepared hydrogel is excitation wavelength-dependent, pH responding, and excellent temperature-sensitive, as well as having good biocompatibility. The prepared hydrogel can also be applied as fluorescence ink in the fields of anti-counterfeit identification and appraisal.

Yellow-emitting carbon-dots-impregnated carboxy methyl cellulose/poly-vinyl-alcohol and chitosan: stable, freestanding, enhanced-quenching Cu2+-ions sensor

2018 ◽  
Vol 6 (16) ◽  
pp. 4508-4515 ◽  
Author(s):  
Qian Wu ◽  
Xiaojie Wang ◽  
Sefiu Abolaji Rasaki ◽  
Tiju Thomas ◽  
Chuanxi Wang ◽  
...  
Keyword(s):  
Fluorescence Quenching ◽  
Carbon Dots ◽  
Vinyl Alcohol ◽  
Methyl Cellulose ◽  
Good Time ◽  
Quantum Yields ◽  
Poly Vinyl Alcohol ◽  
Carboxy Methyl Cellulose ◽  
Time Stability ◽  
Carboxy Methyl

Yellow-emitting carbon dots/polymer-based sensing films with good time stability and high quantum yields were used to sensitively and selectively detect Cu2+ ions due to strengthened aggregation-induced fluorescence quenching.

scholarly journals Temperature-sensitive carbon dots derived from poly(N-isopropylacrylamide) for fluorescence on–off properties

RSC Advances ◽  
2017 ◽  
Vol 7 (18) ◽  
pp. 11149-11157 ◽  
Author(s):  
Zihnil Adha Islamy Mazrad ◽  
Eun Bi Kang ◽  
Nuraeni Nuraeni ◽  
Gibaek Lee ◽  
Insik In ◽  
...  
Keyword(s):  
Fluorescence Intensity ◽  
Carbon Dots ◽  
Temperature Sensitive ◽  
Fluorescent Nanoparticles

Here, we report novel thermo-responsive fluorescent nanoparticles of carbonized poly(N-isopropylacrylamide) (PNIPAAm) through carbonization. The partial carbonized PNIPAAm (F-PNIPAAm) shows reversible capability based on fluorescence intensity.

Potential Ganciclovir Liposomal Thermoreversible Gel for Ophthalmic Delivery Using Box-Behnken Statistical Design and Efficacy Assessment Study in Rabbit Model

2019 ◽  
Vol 9 (7) ◽  
pp. 950-957
Author(s):  
Yanjuan Sheng ◽  
Yanni Zhu
Keyword(s):  
Drug Release ◽  
Ex Vivo ◽  
Rabbit Model ◽  
Methyl Cellulose ◽  
Temperature Sensitive ◽  
Potential Candidate ◽  
Core System ◽  
Thermoreversible Gel

The present study focuses on development of novel thermoreversible ophthalmic drug delivery system using Ganciclovir as potential candidate for treatment of various ocular infections. The formulation was prepared for thermoreversible gel which incorporates liposomes of Ganciclovir as core system. Thermoreversible gel prolongs delivery of drug with use of combination of polymers like Poloxamer, Hydroxypropyl methyl cellulose. The Poloxamer used here serves as temperature sensitive polymer. Thus prepared system was evaluated for various parameters. Liposomes found to be complies with basic requirement like non-leak ability, high in-vitro drug release with optimum encapsulation efficiency. The results obtained showed that the in situ gel is clear and transparent (prime requirement for ophthalmic product) with high gelling capacity and moderately viscous liquid (1454 cp), highest bioadhesive strength (Dyne/cm2). The ex-vivo study was also done and compared with marketed eye drop formulation. The results showed superiority of in situ gel formulation over eye in sustaining the drug release over prolong period of time. The haemolytic study performed proved the non-haemolytic nature of formulation.

Facile heat reflux synthesis of blue luminescent carbon dots as optical nanoprobes for cellular imaging

2017 ◽  
Vol 41 (2) ◽  
pp. 702-708 ◽  
Author(s):  
Xianfeng Zhang ◽  
Jingbo Lu ◽  
Xianqing Li ◽  
Liucheng Chai ◽  
Yuhong Jiao
Keyword(s):  
Carbon Dots ◽  
Cellular Imaging ◽  
Luminescence Properties ◽  
Temperature Sensitive ◽  
Optical Nanoprobes

Carbon dots with good temperature-sensitive photoluminescence are facilely synthesized and their luminescence properties and cellular imaging applications are investigated.

scholarly journals DEVELOPMENT AND EVALUATION OF AN IN SITU THERMOGELLING SYSTEM OF OFLOXACIN FOR CONTROLLED OCULAR DELIVERY

2019 ◽  
pp. 567-570 ◽  
Author(s):  
ANANTH PRABHU ◽  
MARINA KOLAND
Keyword(s):  
Drug Release ◽  
In Vitro Release ◽  
Methyl Cellulose ◽  
Poloxamer 407 ◽  
Temperature Sensitive ◽  
Gelation Temperature ◽  
Mucoadhesive Polymers ◽  
In Situ Gelling

Objective: The purpose of this study was to develop an in situ ocular gel of ofloxacin which aimed to prolong corneal residence time while controlling drug release. Method: In situ gelling solutions were prepared from Poloxamer 407, a temperature-sensitive gelling polymer and to which, mucoadhesive polymers such as hydroxypropyl methyl cellulose 15 cps and polyvinyl alcohol (PVA) were included to provide corneal adhesion. Drug incorporated gels were prepared and evaluated for their appearance, pH, gelation temperature, and in vitro drug release studies. Results: Incorporation of the drug into the formulation increased the gelation temperature while the addition of mucoadhesive polymers decreased the gelation temperature. Increasing the concentration of bio-adhesive polymers retarded the release of ofloxacin from the poloxamer solutions and drug release was sustained over a period of 9 h. PVA had no significant effect on the gelation temperature and could not sustain the drug release for a longer duration. The in vitro release profiles of the drug from all the formulations could be best expressed by Higuchi’s equation which indicated that gels followed matrix diffusion process and drug release from gel formulations followed first-order process. Conclusion: The results showed that the developed system would be promising in the treatment of ocular infections with the combined advantages of ease of administration, the accuracy of dosing, increased bioavailability, and prolonged retention time.

One Stone, Two Birds: pH- and Temperature-Sensitive Nitrogen-Doped Carbon Dots for Multiple Anticounterfeiting and Multiple Cell Imaging

2020 ◽  
Vol 12 (18) ◽  
pp. 20849-20858 ◽  
Author(s):  
Xue-Chun Yang ◽  
Qianli Li ◽  
Ming Tang ◽  
Yun-Ling Yang ◽  
Woochul Yang ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Cell Imaging ◽  
Temperature Sensitive ◽  
Nitrogen Doped ◽  
Multiple Cell ◽  
Doped Carbon Dots ◽  
Nitrogen Doped Carbon

Hepatocyte Alterations in Guinea Pigs FED Polychlorinated Biphenyls (PCBs), Dibenzodioxins (PCDD), AND DIBENZOFURANS (PCDF)

1982 ◽  
Vol 40 ◽  
pp. 56-57
Author(s):  
J. N. Turner ◽  
D. N. Collins
Keyword(s):  
Guinea Pigs ◽  
Room Temperature ◽  
Dose Group ◽  
Methyl Cellulose ◽  
Uranyl Acetate ◽  
Target Organ ◽  
Office Building ◽  
Lead Citrate ◽  
Control Groups ◽  
Cooling Fluid

A fire involving an electric service transformer and its cooling fluid, a mixture of PCBs and chlorinated benzenes, contaminated an office building with a fine soot. Chemical analysis showed PCDDs and PCDFs including the highly toxic tetra isomers. Guinea pigs were chosen as an experimental animal to test the soot's toxicity because of their sensitivity to these compounds, and the liver was examined because it is a target organ. The soot was suspended in 0.75% methyl cellulose and administered in a single dose by gavage at levels of 1,10,100, and 500mgm soot/kgm body weight. Each dose group was composed of 6 males and 6 females. Control groups included 12 (6 male, 6 female) animals fed activated carbon in methyl cellulose, 6 males fed methyl cellulose, and 16 males and 10 females untreated. The guinea pigs were sacrificed at 42 days by suffocation in CO2. Liver samples were immediately immersed and minced in 2% gluteraldehyde in cacadylate buffer at pH 7.4 and 4°C. After overnight fixation, samples were postfixed in 1% OsO4 in cacodylate for 1 hr at room temperature, embedded in epon, sectioned and stained with uranyl acetate and lead citrate.

Oncogenesis and the Lucké Virus

1968 ◽  
Vol 26 ◽  
pp. 200-201
Author(s):  
A. E. Vatter ◽  
J. Zambernard
Keyword(s):  
Rna Viruses ◽  
Vegetative State ◽  
Temperature Sensitive ◽  
Structural Level ◽  
Oncogenic Viruses ◽  
Dna Viruses ◽  
Leopard Frogs ◽  
Renal Adenocarcinoma ◽  
Induced Tumors ◽  
Northern Leopard Frogs

Oncogenic viruses, like viruses in general, can be divided into two classes, those that contain deoxyribonucleic acid (DNA) and those that contain ribonucleic acid (RNA). The RNA viruses have been recovered readily from the tumors which they cause whereas, the DNA-virus induced tumors have not yielded the virus. Since DNA viruses cannot be recovered, the bulk of present day investigations have been concerned with RNA viruses.The Lucké renal adenocarcinoma is a spontaneous tumor which occurs in northern leopard frogs (Rana pipiens) and has received increased attention in recent years because of its probable viral etiology. This hypothesis was first advanced by Lucké after he observed intranuclear inclusions in some of the tumor cells. Tumors with inclusions were examined at the fine structural level by Fawcett who showed that they contained immature and mature virus˗like particles.The use of this system in the study of oncogenic tumors offers several unique features, the virus has been shown to contain DNA and it can be recovered from the tumor, also, it is temperature sensitive. This latter feature is of importance because the virus can be transformed from a latent to a vegetative state by lowering or elevating the environmental temperature.

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