Abstract
Background HIV/AIDS is a critical public health concern worldwide. This article aimed to demonstrate th trends of HIV/AIDS burden from 1990 to 2019.Methods Data was extracted from the Global Burden of Disease study (GBDs) 2019. Estimated annual percentage change (EAPC) and age-standardized rate (ASR) were estimated to quantify the trends at global, regional and national levels.Results During the period 1990-2004, the trend in incidence of HIV/AIDS was stable globally. Whereas the trends in prevalence, death and disability-adjusted life years (DALYs) had pronounced increasing trends, with the respective EAPCs were 7.47 (95%confidence interval [CI]: 5.84 to 9.12), 10.85(95%CI: 8.90 to 12.84), and 10.40(95%CI: 8.47 to 12.36). Meanwhile, the pronounced increasing trends were seen in low-resource settings, particularly that of death in Oceania and South Asia, in which the respective EAPCs were 44.76 (95%CI: 40.81 to 48.82) and 40.82 (95%CI: 34.31 to 47.64). However, the global trends in incidence, death and DALYs of HIV/AIDS pronouncedly decreased from 2005 to 2019, with the respective EAPCs were −2.68(95%CI: −2.82 to −2.53), −6.73(95%CI: −6.98 to −6.47) and −6.75(95%CI: −6.95 to −6.54). Whereas prevalence showed increasing trend (EAPC: 0.71, 95%CI: 0.54 to 0.87). Decreasing trends of HIV/AIDS were observed in most regions and countries, particularly that of death and DALYs in Burundi respectively were −15.28 (95%CI: −16.08 to −14.47) and −15.07 (95%CI: −15.79 to −14.33). Conclusions Decreasing trends of HIV/AIDS were observed worldwide over the past 15 years. However, HIV/AIDS remains one of the most critical causes of health loss worldwide, which emphasized the effective prevention and control strategies.