350. Drug delivery for colon cancer therapy by doxorubicin with oligonucleotide modified gold-nanoparticles

2016 ◽  
Vol 42 (9) ◽  
pp. S152-S153
Author(s):  
M.J. Baek ◽  
D.K. Park ◽  
S.J. Lee ◽  
J.Y. Kim ◽  
I.Y. Kim ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Colon Cancer ◽  
Gold Nanoparticles ◽  
Cancer Therapy

scholarly journals Structural characterization of functionalized gold nanoparticles for drug delivery in cancer therapy: a NMR based approach

2015 ◽  
Vol 17 (29) ◽  
pp. 18971-18979 ◽  
Author(s):  
Sílvia C. Coelho ◽  
Maria Rangel ◽  
Maria C. Pereira ◽  
Manuel A. N. Coelho ◽  
Galya Ivanova
Keyword(s):  
Drug Delivery ◽  
Gold Nanoparticles ◽  
Cancer Therapy ◽  
Structural Characterization ◽  
Au Nanoparticles ◽  
Functionalized Gold Nanoparticles ◽  
Loaded Surface

Structure of Bortezomib loaded, surface functionalized Au nanoparticles.

Recent advances in combinatorial cancer therapy via multifunctionalized gold nanoparticles

Nanomedicine ◽  
2020 ◽  
Vol 15 (12) ◽  
pp. 1221-1237
Author(s):  
Touqeer Ahmad ◽  
Rizwana Sarwar ◽  
Ayesha Iqbal ◽  
Uzma Bashir ◽  
Umar Farooq ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Gold Nanoparticles ◽  
Cancer Therapy ◽  
Targeted Drug Delivery ◽  
Photothermal Therapy ◽  
Therapeutic Implications ◽  
Therapeutic Applications ◽  
Diagnosis Of Cancer ◽  
Targeted Drug ◽  
Cancerous Cells

The diverse behavior of nanogold in the therapeutic field is related to its unique size and shape. Nanogold offers improvements in modern diagnostic and therapeutic implications, increases disease specificity and targeted drug delivery, and is relatively economical compared with other chemotherapeutic protocols. The diagnosis of cancer and photothermal therapy improve drastically with the implementation of nanotechnology. Different types of nanoparticles, that is, gold silica nanoshells, nanorods and nanospheres of diverse shapes and geometries, are used widely in the photothermal therapy of cancerous cells and nodules. Numerous reviews have been published on the therapeutic applications of gold nanoparticles, but studies on combinatorial applications of nanogold in cancer therapy are limited. This review focuses on the combinatorial cancer therapy using optical properties of nanogold with different shapes and geometries, and their therapeutic applications in cancer diagnosis, photothermal therapy, cancer imaging and targeted drug delivery.

scholarly journals Edible Ginger-derived Nano-lipids Loaded with Doxorubicin as a Novel Drug-delivery Approach for Colon Cancer Therapy

2016 ◽  
Vol 24 (10) ◽  
pp. 1783-1796 ◽  
Author(s):  
Mingzhen Zhang ◽  
Bo Xiao ◽  
Huan Wang ◽  
Moon Kwon Han ◽  
Zhan Zhang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Colon Cancer ◽  
Cancer Therapy ◽  
Novel Drug ◽  
Delivery Approach

Ultra-small gold nanoparticles self-assembled by gadolinium ions for enhanced photothermal/photodynamic liver cancer therapy

2020 ◽  
Author(s):  
Bei Li ◽  
Lan Sun ◽  
Tao Li ◽  
Yingge Zhang ◽  
Xiao Ya Niu ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Gold Nanoparticles ◽  
Cancer Therapy ◽  
Liver Cancer ◽  
Physicochemical Properties ◽  
Biomedical Research ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Imaging Agents ◽  
Gold Nanomaterials

Gold nanomaterials are widely used in biomedical research as drug delivery systems, imaging agents and therapeutic materials owing to their unique physicochemical properties and high biocompatibility. In this study, we...

scholarly journals Laser-triggered collaborative chemophotothermal effect of gold nanoparticles for targeted colon cancer therapy

2020 ◽  
Vol 130 ◽  
pp. 110492
Author(s):  
Yajie Zhang ◽  
Lu Zhou ◽  
Jingwei Tan ◽  
Jianling Liu ◽  
Xiaoqing Shan ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Gold Nanoparticles ◽  
Cancer Therapy

Role of Gold Nanoparticles in Drug Delivery and Cancer Therapy

2021 ◽  
pp. 124-140
Author(s):  
Mohammad Nadeem Lone ◽  
Irshad Ahmad Wani ◽  
Gulam Nabi Yatoo ◽  
Zubaid U-Khazir ◽  
Javid Ahmad Banday
Keyword(s):  
Drug Delivery ◽  
Gold Nanoparticles ◽  
Cancer Therapy ◽  
High Surface ◽  
High Surface Area ◽  
Volume Ratio ◽  
Drug Carriers ◽  
Photothermal Effect ◽  
Intracellular Release ◽  
High Dispersity

Among various nanoparticles (NPs), gold nanoparticles (GNPs) gained valuable attention in the field of medicine because of some unique properties like small size and high surface area-to-volume ratio, inert nature, stability, high dispersity, non-cytotoxicity, and biocompatibility. These NPs are evolving as promising agents especially in drug carriers, cancer therapy, and constantly being exploring as photothermal agents, contrast agents, and radiosensitisers. Besides, GNPs interact with thiols that provides an effective and selective means of controlled intracellular release. At the present, cancer patients are increasing rapidly at national and international levels. In this chapter, efforts have taken to highlight the importance of GNPs, their critical mediation in drug delivery, as sensors for probing and imaging tumors and anti-angiogenesis. More importantly, this short piece of analysis highlights the photothermal effect of GNPs in therapy and as radiosensitizers. Finally, the current challenges and future perspectives of GNP's in cancer management are also discussed.

scholarly journals Application of Marine-Based Gold Nanomaterials in Cancer Therapy: A Mini-Review

2021 ◽  
Author(s):  
Neda Baghban ◽  
Arezoo Khoradmehr ◽  
Iraj Nabipour ◽  
Amin Tamadon
Keyword(s):  
Drug Delivery ◽  
Gold Nanoparticles ◽  
Cancer Therapy ◽  
Drug Delivery System ◽  
Delivery System ◽  
Medical Sciences ◽  
Gold Nanocomposites ◽  
Marine Natural Compound ◽  
Gold Nanomaterials ◽  
Near Future

Cancer is one of the health concerns in modern societies. The application of nanotechnology in medical sciences has created new possibilities for the diagnosis, imaging and the treatment of tumors in humans. The present article reviews the application of marine-based gold nanoparticles in diagnosing and treating cancer. The main data were collected from research article on the application of different marine-based gold nanoparticles in detecting and imaging cancer cells as well as in drug delivery system in treatment of cancer. Chitosan is the most used marine natural compound used to fabricate gold nanocomposites and the most reported application of this type of nano-composites is related to drug delivery system. Despite the excellent anticancer potential of different marine natural products, less studies have been conducted on the use of their compositions with gold nanoparticles in cancer therapy than other materials. Moreover, most reports available in this filed are related to their application as a drug delivery system not anticancer drug. In general, there are still challenges and limitations to the use of nanoparticles in medicine, it is hoped that in the near future nanoparticles will create a dramatic revolution not only in oncology but also in medicine.

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