Cavum septum pellucidum and adhesio interthalamica in schizophrenia: an MRI study

2006 ◽  
Vol 21 (5) ◽  
pp. 291-299 ◽  
Author(s):  
José Alexandre de Souza Crippa ◽  
Antonio Waldo Zuardi ◽  
Geraldo F. Busatto ◽  
Rafael Faria Sanches ◽  
Antonio Carlos Santos ◽  
...  
Keyword(s):  
Case Series ◽  
Septum Pellucidum ◽  
Group Differences ◽  
Resonance Imaging ◽  
Brain Abnormalities ◽  
Cavum Septum Pellucidum ◽  
Neurodevelopmental Model ◽  
Male Patients ◽  
Magnetic Resonance Imaging Mri ◽  
Mri Study

AbstractSeveral studies have independently suggested that patients with schizophrenia are more likely to have an enlarged cavum septum pellucidum (CSP) and an absent adhesio interthalamica (AI), respectively. However, neither finding has been consistently replicated and it is unclear whether there is an association between these two midline brain abnormalities. Thus, we compared the prevalence of absent AI and the prevalence, size and volume of CSP in 38 patients with schizophrenia and 38 healthy controls using magnetic resonance imaging (MRI). There were no between group differences in the presence or volume of CSP; however, an enlarged CSP was commoner among patients than controls. There was also a positive correlation between CSP ratings and volumes. No differences in the presence or absence of the AI were found between patients and controls; however, an absent AI was commoner in male patients with schizophrenia than females. There was absolutely no overlap between the presence of a large CSP and an absence of AI. In conclusion, our findings are in line with several case series and other MRI investigations that have shown a higher incidence of putatively developmental brain abnormalities in patients with schizophrenia, particularly in males, and support the neurodevelopmental model of this disorder.

Cavum septum pellucidum in schizophrenia, affective disorder and healthy controls: a magnetic resonance imaging study

1993 ◽  
Vol 23 (2) ◽  
pp. 319-322 ◽  
Author(s):  
George J. Jurjus ◽  
Henry A. Nasrallah ◽  
Stephen C. Olson ◽  
Steven B. Schwarzkopf
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Imaging Study ◽  
Septum Pellucidum ◽  
Healthy Controls ◽  
Resonance Imaging ◽  
Cavum Septum Pellucidum ◽  
Clinical Difference ◽  
Magnetic Resonance Imaging Mri ◽  
Mri Study

SynopsisMany structural brain abnormalities have been described in schizophrenia, consistent with a neurodevelopmental model for this disease. We report here a study of the cavum septum pellucidum (CSP) in schizophrenia compared to control groups, as well as the clinical correlates of this congenital anomaly in schizophrenia. We conducted a magnetic resonance imaging (MRI) study to compare rates of CSP in schizophrenia (N = 67) v. psychiatric controls (bipolar and schizoaffective, N = 60) and healthy controls (N = 37). Of the controls 18·9 %, and of all psychotic subjects 18·1 % had a CSP of any size and there was no difference in the frequency of large CSP among the groups. Males had higher rates of CSP than females (25% v. 9·7%, P = 0·01) in all groups. Schizophrenics had higher CSP rates than affective patients (25%, v. 10%, P = 0·02). No clinical difference was found between schizophrenics with or without CSP.

scholarly journals Cavum Septum Pellucidum Epidermoid- An Extremely rare occurrence

2018 ◽  
Vol 15 (1) ◽  
pp. 32-34
Author(s):  
Dwarakanath Srinivas ◽  
Raghavendra Chalikwar ◽  
Anita Mahadevan ◽  
Sampath Somanna
Keyword(s):  
Emergency Services ◽  
Septum Pellucidum ◽  
Mass Lesion ◽  
Cranial Computed Tomography ◽  
Extensive Literature ◽  
Resonance Imaging ◽  
Cavum Septum Pellucidum ◽  
Transcallosal Approach ◽  
History Of ◽  
Magnetic Resonance Imaging Mri

Supratentorialintraventricularepidermoids are very rare and midline septal pellucidal epidermoids are even more uncommon with only one case being reported in available literature. A 42-year-old lady with no previous complaints was admitted to the emergency services with history of intermittent headache, vomiting and giddiness of 3 months duration. A cranial computed tomography (CT) revealed a hypodense, non-enhancing intraventricular mass lesion and cranial magnetic resonance imaging (MRI) demonstrated a non-enhancing mass lesion in the septum pellucidum suggestive of an epidermoid. She underwent endoscopic-assisted surgery via an interhemispheric transcallosal approach. Intra-operatively, the lesion was located in the enlarged cavum septum pellucidum and was removed totally. An extensive literature review unearthed only 10 cases of intraventricular epidermoids and one in the septum pellucidum. We present only the second case of a midline septum pellucidum epidermoid and reflect on the paucity of supratentorial intraventricular midline epidermoids.Nepal Journal of Neuroscience 15:32-34, 2018

scholarly journals Spontaneous dissolution of a cyst located within the septum pellucidum in a patient with sarcoidosis: a case report

2021 ◽  
Vol 10 (1) ◽  
pp. 205846012098551
Author(s):  
Martina Kastrup Loft ◽  
Søren Rafael Rafaelsen ◽  
Malene Roland V Pedersen
Keyword(s):  
Magnetic Resonance Imaging ◽  
Septum Pellucidum ◽  
Unknown Etiology ◽  
Mediastinal Lymph Nodes ◽  
Resonance Imaging ◽  
Multisystem Disease ◽  
Meningeal Enhancement ◽  
Cerebral Magnetic Resonance Imaging ◽  
Cavum Septum Pellucidum ◽  
Contrast Enhanced

Sarcoidosis is a granulomatous multisystem disease of unknown etiology. Typically, the disease affects the lungs, causing enlargement of the mediastinal lymph nodes, but other organs can be affected. Neurosarcoidosis is reported in 5–10% of the patients. This case represents a 39-year-old male patient diagnosed with lung sarcoidosis. Due to neurological symptoms, a contrast-enhanced cerebral magnetic resonance imaging was performed. Neurosarcoidosis was presented with meningeal enhancement adjacent to a cyst located within the cavum septum pellucidum. The cyst dissolved spontaneously within six months. The finding of a cyst located within the septum pellucidum is rare.

Epilepsy in Propionic Acidemia: Case Series of 14 Saudi Patients

2018 ◽  
Vol 33 (11) ◽  
pp. 713-717 ◽  
Author(s):  
Afnan AlGhamdi ◽  
Muhammad Talal Alrifai ◽  
Abdullah I. Al Hammad ◽  
Fuad Al Mutairi ◽  
Abdulrahman Alswaid ◽  
...  
Keyword(s):  
Autosomal Recessive ◽  
Case Series ◽  
Brain Magnetic Resonance Imaging ◽  
Propionic Acidemia ◽  
Resonance Imaging ◽  
Mri Findings ◽  
Epileptiform Discharges ◽  
Magnetic Resonance Imaging Mri ◽  
Autosomal Recessive Manner ◽  
Delayed Myelination

Propionic acidemia is an inborn error of metabolism that is inherited in an autosomal recessive manner. It is characterized by a deficient propionyl-CoA carboxylase due to mutations in either of its beta or alpha subunits. In the literature, there is a clear association between propionic acidemia and epilepsy. In this cohort, we retrospectively reviewed the data of 14 propionic acidemia patients in Saudi Arabia and compared the findings to those of former studies. Six of the 14 (43%) patients developed epileptic seizure, mainly focal seizures. All patients were responsive to conventional antiepileptic drugs as their seizures are controlled. The predominant electroencephalographic (EEG) findings were diffuse slowing in 43% and multifocal epileptiform discharges in 14% of the patients. In 1 patient, burst suppression pattern was detected, a pattern never before reported in patients with propionic acidemia. Brain magnetic resonance imaging (MRI) findings mainly consisted of signal changes of the basal ganglia (36%), generalized brain atrophy (43%), and delayed myelination (43%).The most common genotype in our series is the homozygous missense mutation in the PCCA gene (c.425G>A; p. Gly142Asp). However, there is no clear genotype–seizure correlation. We conclude that seizure is not an uncommon finding in patients with propionic acidemia and not difficult to control. Additional studies are needed to further elaborate on genotype–seizure correlation.

T1672 The Effects of Endogenous GLP-1 On Antro-Duodenal Contractility in the Fasted and Fed State: A Magnetic Resonance Imaging (MRI) Study

2009 ◽  
Vol 136 (5) ◽  
pp. A-555
Author(s):  
Elad Kaufman ◽  
Mark Fox ◽  
Michael Wyss ◽  
Zsofia Forras-Kaufman ◽  
Reto Treier ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Resonance Imaging ◽  
Fed State ◽  
Magnetic Resonance Imaging Mri ◽  
Mri Study

Clinical and Magnetic Resonance Imaging Predictors of Disability in Primary and Secondary Progressive Multiple Sclerosis

1996 ◽  
Vol 1 (4) ◽  
pp. 218-222 ◽  
Author(s):  
NA Losseff ◽  
DPE Kingsley ◽  
WI McDonald ◽  
DH Miller ◽  
AJ Thompson
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Magnetic Resonance ◽  
Initial Study ◽  
Progressive Multiple Sclerosis ◽  
Resonance Imaging ◽  
Secondary Progressive ◽  
Short Period ◽  
Magnetic Resonance Imaging Mri ◽  
Mri Study

The role of magnetic resonance imaging (MRI) in predicting disability in multiple sclerosis (MS) remains unclear. In this study 21 patients with primary and secondary progressive MS were reviewed 5 years following a serial MRI study of 6 months duration. In the secondary progressive group (n=11) there was a significant relationship between the occurrence of enhancing lesions and clinical relapses during the initial 6 months and increase in diability 5 years later. For both groups change in disability over the initial study period was predictive of outcome. These results suggest that the presence and frequency of gadolinium enhancement (a marker of inflammation) and changes in disability over a short period are predictive of future deterioration in progressive patients.

Leber’s hereditary optic neuropathy associated with a multiple-sclerosis-like picture in a man

2011 ◽  
Vol 17 (6) ◽  
pp. 763-766 ◽  
Author(s):  
Antonella La Russa ◽  
Rita Cittadella ◽  
Virginia Andreoli ◽  
Paola Valentino ◽  
Francesca Trecroci ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Spinal Cord ◽  
Optic Neuropathy ◽  
Brain Mri ◽  
Resonance Imaging ◽  
Gadolinium Enhancement ◽  
Demyelinating Lesions ◽  
Male Patients ◽  
Magnetic Resonance Imaging Mri ◽  
Symptoms And Signs

A 35-year-old young man displayed Leber’s optic neuropathy (LHON) due to T14484C and multiple sclerosis (MS) phenotype that was dominated by symptoms and signs of spinal cord impairment. Magnetic resonance imaging (MRI) revealed demyelinating lesions extending from D6 to D11 in the spinal cord with gadolinium enhancement, while only three linear demyelinating lesions were seen on brain MRI. In the literature, a major involvement of the spinal cord was already reported in three of four male patients with the 14484 LHON mutation who developed MS, but the reasons of this peculiar association remain unknown, and further research in this area is needed.

scholarly journals Simultaneous PET/Mri in Stroke: A Case Series

2015 ◽  
Vol 35 (9) ◽  
pp. 1421-1425 ◽  
Author(s):  
Peter Werner ◽  
Dorothee Saur ◽  
Vilia Zeisig ◽  
Barbara Ettrich ◽  
Marianne Patt ◽  
...  
Keyword(s):  
Case Series ◽  
Patient Stratification ◽  
Resonance Imaging ◽  
Ovine Model ◽  
Stroke Patients ◽  
Complementary Information ◽  
Systemic Thrombolysis ◽  
Positron Emission ◽  
Magnetic Resonance Imaging Mri ◽  
Post Hoc

Prospective studies on magnetic resonance imaging (MRI)-guided systemic thrombolysis 44.5 hours after stroke onset did not reach their primary end points. It was discussed and observed in post hoc data re-assessment that this was partly because of limited MRI accuracy to measure critical hypoperfusion. We report the first cases of simultaneous [15O]H2O-positron emission tomography (PET)/MRI in stroke patients and an ovine model. Discrepancies between simultaneously obtained PET and MRI readouts were observed that might explain the above current limitations of stroke MRI. By offering highly complementary information, [15O]H2O-PET/MRI might help to identify critically hypoperfused tissue resulting in an improved patient stratification in thrombolysis trials.

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