Mental Pain Expression in Psychopathology and its Assessment as a Therapeutic Outcome Measurement

2016 ◽  
Vol 33 (S1) ◽  
pp. S478-S478 ◽  
Author(s):  
G. Becker ◽  
E. Steiner ◽  
U. Nitzan ◽  
A. Grossman-Giron
Keyword(s):  
Outcome Measurement ◽  
Therapeutic Process ◽  
Pain Scale ◽  
Annihilation Anxiety ◽  
Mental Pain ◽  
Pain Expression ◽  
Important Symptom ◽  
Competing Interest ◽  
One Year

IntroductionEvery theory that explains psychopathology refers to different aspects of mental pain whether it regards annihilation anxiety, fragmentation of the self or feelings of intolerable anguish. The concept of mental pain has proved to be an important symptom in mood disorders in general and suicide in particular (Orbach et al., 2004; Levi et al., 2010; Levinger et al., 2015). Combining the understanding that mental pain is as a part of all forms of psychopathology with the growing interest in assessing therapeutic processes via outcome measures has led to the assumption that the tolerance and severity of mental pain could become powerful outcome measurement. The aim of this study is to assess the Mental Pain Scale (OMMP) and Tolerance to Mental Pain Scale (TMPS) as outcome measurement and to learn about their capabilities to distinguish between different psychopathologies.ObjectiveThe first objective would be to examine patterns of mental pain subscales in different psychopathologies. The second objective is to assess the OMMP and TMPS as outcome measurements.MethodTwo hundred and thirty outpatients were administered a clinical questionnaire battery composed of eight questionnaires. The patients were to fill these questionnaires every 3 months for one year or until the end of their therapy.ResultsWe will present preliminary findings regarding the expressions of mental pain in different kinds of psychopathology and results of 3 months follow-up.ConclusionTolerance and severity of mental pain are a vital to the assessment of psychopathology and should be used as outcome measurement of therapeutic process.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Epigenetics in the Remission of Anorexia Nervosa: A Follow-up Study of Whole-genome Methylation Profiles

2017 ◽  
Vol 41 (S1) ◽  
pp. S102-S102 ◽  
Author(s):  
N. Ramoz ◽  
S. Guillaume ◽  
P. Courtet ◽  
P. Gorwood
Keyword(s):  
Anorexia Nervosa ◽  
Whole Genome ◽  
Biological Processes ◽  
Methylation Of Dna ◽  
Genome Methylation ◽  
The Difference ◽  
Competing Interest ◽  
One Year ◽  
Epigenetic Signatures

IntroductionAnorexia nervosa (AN) is a severe psychiatric disorder. The epigenetic regulations are strongly suggested in AN. We and other groups have performed a whole-genome methylation study (methylome) in AN. We found that the differentially methylated CpG sites are located around genes involved in biological processes in link with embryonic morphogenesis, brain development and its plasticity, in particular adhesion and axon guidance. Here, we study an independent group of 40 AN patients. Furthermore, we have done a follow-up during more than one year, to compare the methylation profiles in subjects that evolve to the remission.ObjectivesOur work is to replicate the methylome study in an independent AN cohort and to characterize profiles of methylation at two times for the same subjects to compare the AN patients that convert to remitters.AimsOur goal is to identify diagnostic and prognostic epigenetic signatures for AN.MethodsOf the 40 AN patients, 18 evolved to remission. Furthermore, the blood samples of the subjects from the 2 times will be investigated, like this, each subject is its own control. Methylation of DNA is measured by using the Infinium HumanMethylation450 BeadChip technology.ResultsComparisons of AN to controls showed similar profiles of methylation involving the same biological processes as previously identified. We are comparing now the difference of methylation between the 18 remitters and the 18 actual AN, taking into account of the two times of samples.ConclusionsWe expect to characterize specific methylation signature of the prognostic of the AN remission.Disclosure of interestThe authors have not supplied their declaration of competing interest.

A case report highlights the neglect problem of pregnancy denial

2017 ◽  
Vol 41 (S1) ◽  
pp. s901-s901
Author(s):  
E. Di Giacomo ◽  
M. Calabria ◽  
F. Colmegna ◽  
B. Pucci ◽  
M. Clerici
Keyword(s):  
Partner Violence ◽  
Home Delivery ◽  
Psychiatric Evaluation ◽  
Childhood Trauma Questionnaire ◽  
Mother And Child ◽  
Entire Pregnancy ◽  
Competing Interest ◽  
One Year ◽  
Pregnancy Denial

Pregnancy denial was observed in a patient after her second delivery. Contrary to the first pregnancy, she denied weight gain, body changes and baby movements. She reported using a contraceptive pill throughout the entire pregnancy. After a short home delivery without assistance, she was admitted to obstetrical department and referred for psychiatric evaluation. Mrs. T. accepted psychiatric follow-up appointments and was followed up for 6 months. She was initially assessed using the SCID II Interview, beck anxiety and depression interview, WHOQOL (WHO quality of life), and childhood trauma questionnaire. She denied pregnancy concealment and during the period of assessment and follow-up there was no evidence of intimate partner violence. Her female newborn was healthy without consequences of oestrogen/progesteron absorption (hypoplastic left heart syndrome, gastroschisis, hypospadias or congenital urinary trait anomalies) in one year follow up. The patient was discharged after 6 months of clinical outpatient follow-up. This case stresses and emphasizes the health and risk outcomes for both mother and child linked to an underestimated but serious phenomenon such as the denial of pregnancy.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals The treatment of coccydynia in adolescents

2020 ◽  
Vol 1 (5) ◽  
pp. 115-120
Author(s):  
Ante Matti Kalstad ◽  
Rainer Günter Knobloch ◽  
Vilhjalmur Finsen
Keyword(s):  
Pain Scale ◽  
Adult Patients ◽  
Injection Therapy ◽  
Control Group ◽  
Treatment Results ◽  
Results Of Treatment ◽  
Adolescent Patients ◽  
Numeric Pain Scale ◽  
One Year

Aims To determine if the results of treatment of adolescents with coccydynia are similar to those found in adults. Adult patients with coccydynia may benefit from injection therapy or operative treatment. There is little data evaluating treatment results in adolescents. We have treated adolescent patients similarly to adults and compared the outcomes. Methods Overall, 32 adolescents with coccydynia were treated at our institution during a seven-year period; 28 responded to final follow-up questionnaires after a minimum of one year, 14 had been treated with only injection therapy, and 14 had been operated with coccygectomy. We collected data with regards to pain while sitting, leaning forward, rising from a sitting position, during defecation, while walking or jogging, and while travelling in trains, planes, or automobiles. Pain at follow-up was registered on a numeric pain scale. Each adolescent was then matched to adult patients, and results compared in a case control fashion. The treatment was considered successful if respondents were either completely well or much better at final follow-up after one to seven years. Results Out of the 28 treated adolescents, 14 were regarded as successfully treated. Seven were somewhat better, and the remaining seven were unchanged. In the adult control group the corresponding number was 15 successfully treated, eight patients were somewhat better, and five were unchanged. Six of the 14 successfully treated adolescents had been operated. There were no significant differences between the groups in the various registered domains, or on numeric pain scale. Conclusion Treatment results in adolescent patients seem similar to those in adults. The long-term success rate of injection therapy is low. In case of injection treatment failure, operation may be considered, also in adolescents.

scholarly journals The treatment of coccydynia in adolescents

2020 ◽  
Vol 1 (5) ◽  
pp. 115-120 ◽  
Author(s):  
Ante Matti Kalstad ◽  
Rainer Günter Knobloch ◽  
Vilhjalmur Finsen
Keyword(s):  
Pain Scale ◽  
Adult Patients ◽  
Injection Therapy ◽  
Control Group ◽  
Treatment Results ◽  
Results Of Treatment ◽  
Adolescent Patients ◽  
Numeric Pain Scale ◽  
One Year

Aims To determine if the results of treatment of adolescents with coccydynia are similar to those found in adults. Adult patients with coccydynia may benefit from injection therapy or operative treatment. There is little data evaluating treatment results in adolescents. We have treated adolescent patients similarly to adults and compared the outcomes. Methods Overall, 32 adolescents with coccydynia were treated at our institution during a seven-year period; 28 responded to final follow-up questionnaires after a minimum of one year, 14 had been treated with only injection therapy, and 14 had been operated with coccygectomy. We collected data with regards to pain while sitting, leaning forward, rising from a sitting position, during defecation, while walking or jogging, and while travelling in trains, planes, or automobiles. Pain at follow-up was registered on a numeric pain scale. Each adolescent was then matched to adult patients, and results compared in a case control fashion. The treatment was considered successful if respondents were either completely well or much better at final follow-up after one to seven years. Results Out of the 28 treated adolescents, 14 were regarded as successfully treated. Seven were somewhat better, and the remaining seven were unchanged. In the adult control group the corresponding number was 15 successfully treated, eight patients were somewhat better, and five were unchanged. Six of the 14 successfully treated adolescents had been operated. There were no significant differences between the groups in the various registered domains, or on numeric pain scale. Conclusion Treatment results in adolescent patients seem similar to those in adults. The long-term success rate of injection therapy is low. In case of injection treatment failure, operation may be considered, also in adolescents.

Eating Disorders and Sexuality: A Complex Relationship

2017 ◽  
Vol 41 (S1) ◽  
pp. S36-S37
Author(s):  
V. Ricca ◽  
G. Castellini ◽  
L. Lelli ◽  
F. Rotella ◽  
A.M. Monteleone ◽  
...  
Keyword(s):  
Eating Disorders ◽  
Sexual Function ◽  
Sexual Functioning ◽  
Recovery Process ◽  
Behavioural Therapy ◽  
Eating Disorder Examination ◽  
Regular Menses ◽  
Competing Interest ◽  
One Year

IntroductionThe relationships between Eating Disorders (EDs) and sexuality are complex, and of interest for researchers and clinicians.ObjectiveTo identify psychopathological and clinical factors associated with restoration of regular menses and sexual function in EDs patients.AimsTo evaluate the role of sexuality as a moderator of the recovery process after an individual Cognitive Behavioural Therapy (CBT).Methods39 Anorexia Nervosa (AN) and 40 Bulimia Nervosa (BN) female patients were evaluated by means of a face-to-face interview, self-reported questionnaires, including Eating Disorder Examination Questionnaire and Female Sexual Function Index, and blood sample for hormonal levels and biomarkers. The assessments were repeated at baseline, at one year follow up, and at three years follow up.ResultsAfter CBT, both AN and BN patients showed a significant improvement of sexual functioning, which was associated with a reduction of core psychopathology. AN patients who recovered regular menses demonstrated a better improvement across time of psychopathological and clinical features, and were more likely to maintain these improvements at follow up. Recovery of regular menses and improvement of sexuality at the end of CBT were associated with a higher probability to have a full recovery at three years follow up.ConclusionsThese results challenge a concept of recovery in EDs exclusively based on weight restoration or behavioral changes. An assessment including sexual functioning and core psychopathology might identify the residual pathological conditions, and it is able to provide information regarding the long term recovery process.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Association between patient's personality traits and outcome of hospital treatment of opioid addiction

2016 ◽  
Vol 33 (S1) ◽  
pp. S296-S296 ◽  
Author(s):  
M. Delic ◽  
K. Kajdiž ◽  
P. Pregelj
Keyword(s):  
Risk Factors ◽  
Treatment Outcome ◽  
Personality Traits ◽  
Illicit Drugs ◽  
Hospital Treatment ◽  
Duration Of Treatment ◽  
Research Interview ◽  
Competing Interest ◽  
One Year

IntroductionDespite different treatment approaches many drug addicted patients continue to use drugs during and after treatment.ObjectivesPersonality traits are considered risk factors for drug use, and, in turn, the psychoactive substances impact individuals’ traits.AimsTo describe the sample of 186 opioid addicted patients entered hospital treatment and assessing the differences in personality traits between abstinent and non-abstinent after one year.MethodsA cohort of 186 patients consecutively admitted to the detoxification unit was investigated. The research interview, the Big Five Inventory (BFI), the Treatment Outcomes Profile (TOP) were administered during the first week of admission to the detoxification unit. Urine test was administered on the day of admission and at each follow-up point in combination with the TOP (after three, six and twelve months). Illicit drugs abstinence during one year after intake was selected as a treatment outcome measure.ResultsTwelve months after admission 82 (44.9%) patients abstained completely. Agreeable patients remain in treatment longer (r = 0.20, P = 0.07). Extraversion and openness are negatively correlated with abstinence after six and twelve months (r = –0.15, P = 0.041; r = –0.15, P = 0.044). Neuroticism is in negative correlation with duration of treatment (r = –0.20, P = 0.006). Patients who are less open to new experiences are more likely to abstain from drugs 6 months after admission (r = –0.17, P = 0.021).ConclusionPersonality measured with BFI correlates with treatment outcome poorly. At the same time personality could have an important role in responding to treatment, but personality traits could be at the same time protective as well as risk factors.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Radial Shock Wave Therapy for Plantar Fasciitis: A One Year Follow-Up Study / Радиальная ударно-волновая терапия при подошвенном фасциите; прослеживание в течение года

Folia Medica ◽  
2013 ◽  
Vol 55 (1) ◽  
pp. 42-48 ◽  
Author(s):  
Elena M. Ilieva
Keyword(s):  
Shock Wave ◽  
Plantar Fasciitis ◽  
Outcome Measurement ◽  
Walking Distance ◽  
Treatment Modalities ◽  
Shock Wave Therapy ◽  
Duration Of Symptoms ◽  
Mean Values ◽  
One Year

Abstract The vast majority of published papers on the efficacy of extracorporeal shockwave therapy (ESWT) have come up with rather controversial results in patients with plantar fasciitis. The aim of the present study was to investigate the effect of radial shock wave therapy in patients with chronic proximal plantar fasciitis. Material and methods: Twenty-one patients were included in the study (mean age 51.29 ± 2.02 yrs, mean duration of symptoms 10.14 ± 1.11 mos). Radial shock wave therapy was administered in five sessions. Total number of shocks per session was 2500 at a pressure of 2.5 bars. Visual analog scale (VAS) and a modification of the clinical rating system of the American Orthopedic Foot and Ankle Society (AOFAS) were used for outcome measurement. The patients were assessed before treatment and followed up 3, 6, and 12 months after end of treatment. Results: Statistically significant improvement in pain and functional capacity was found after completion of treatment in comparison with baseline; the improvement was preserved throughout a one-year follow-up. VAS mean score for pain showed changes in pain while walking the first few steps in the morning from 6.28 ± 0.4 before therapy to 2.85 ± 0.48 after treatment and to 1.52 ± 0.31 at 3 months, to 1.09 ± 0.25 at 6 months, and to 0.52 ± 0.14 at 12 months of follow up (p < 0.001). Similar dynamics was observed in pain intensity during daily activities, at rest, in the evening and upon compression. The AFOAS score showed a statistically significant reduction in pain - from 11.90 ± 2.35 at baseline to 31.90 ± 1.48 after the end of interventions (p < 0.001), and to 39.52 ± 0.47 at one year of follow-up (p < 0.001). The mean values of the evaluation reflecting activity limitations and support requirements increased from 3.85 ± 0.42 to 7.85 ± 0.46 after treatment and to 9.71 ± 0.19 at one year of follow up (p < 0.001). Similar dynamics was seen in the maximum walking distance and walking surfaces. Gait abnormalities changed from 3.43 ± 0.50 at baseline to 6.28 ± 0.59 after treatment (p < 0.001). Conclusion: Based on the results of this study we could conclude that radial shock wave therapy is a safe non-invasive method of treatment. Our preliminary findings indicate that it could be an effective treatment of choice for patients with chronic plantar fasciitis that is recalcitrant to other conservative treatment modalities.

scholarly journals Combined vitrectomy, near-confluent endolaser, bevacizumab and cyclophotocoagulation for neovascular glaucoma

2020 ◽  
Author(s):  
P. Strzalkowski ◽  
A. Strzalkowska ◽  
W. Göbel ◽  
T. Ach ◽  
N.A. Loewen ◽  
...  
Keyword(s):  
Central Retinal Artery Occlusion ◽  
Case Series ◽  
Intravitreal Bevacizumab ◽  
Retinal Artery Occlusion ◽  
Neovascular Glaucoma ◽  
Pain Scale ◽  
Artery Occlusion ◽  
Panretinal Photocoagulation ◽  
One Year

AbstractPurposeEvaluated the safety and efficacy of an integrative surgical approach to neovascular glaucoma (NVG).MethodsConsecutive interventional case series of NVG with one-year follow-up. Eyes underwent pars plana vitrectomy, near-confluent panretinal photocoagulation, intravitreal bevacizumab, and transscleral cyclophotocoagulation. Phakic eyes underwent concomitant cataract surgery. Best-corrected visual acuity (BCVA, logMAR), intraocular pressure (IOP, mmHg), glaucoma medication score (GMS), visual analog pain scale (VAPS, 0-10) were recorded at baseline, and 1, 3, 6 and 12 months. Blind eyes were excluded.Results83 eyes of 83 patients (53 male, 30 female, mean age 74.6±11.6 years) were included and 53 completed a one-year follow-up. NVG underlying conditions included retinal vein occlusion (n=41), proliferative diabetic retinopathy (n=25), central retinal artery occlusion (n=10), and ocular ischemic syndrome (n=6). Mean IOP decreased postoperatively from 46.0±10.3 mmHg to 14.2±8.9 mmHg (p<0.001), GMS from 4.8 to 1.8 (p<0.001) and VAPS from 6 to 0. BCVA was unchanged. All postoperative complications had resolved at 1 month postop. 26 eyes did not require additional surgical treatment during follow-up.ConclusionsA single, comprehensive surgery session was able to significantly lower IOP, reduce GMS and control pain.

scholarly journals PERCUTANEOUS DISCECTOMY: A CURRENT TREATMENT FOR LUMBAR DISC HERNIATION

2016 ◽  
Vol 15 (2) ◽  
pp. 127-130 ◽  
Author(s):  
Pablo Gerardo Lima-Ramírez ◽  
David Benavides-Rodríguez ◽  
Juan Yahir Viera-Ordóñez ◽  
José Augusto Ruíz-Gurría ◽  
Iván del Castillo-Vergara ◽  
...  
Keyword(s):  
Lumbar Disc Herniation ◽  
Disc Herniation ◽  
Lumbar Disc ◽  
Pain Scale ◽  
Current Treatment ◽  
Prospective Longitudinal Study ◽  
Student’S T ◽  
One Year ◽  
Prospective Longitudinal

ABSTRACT Objective: Describe the functional outcomes of patients with contained lumbar disc herniation (L4-L5, L5-S1) treated with manual percutaneous nucleotomy (MPN) and demonstrate that it remains a technique with good results. Methods: A prospective, longitudinal study with 110 patients contained with lumbar disc herniation (LDH) treated with (MPN). The evaluation was pre-surgical and 4, 30, 180 and 365 days after the surgery. We used Numeric Pain Scale (NPS), Oswestry Disability Index (ODI) and Macnab criteria. Descriptive and inferential statistics for differences. Results: N=110: 58 (52.72%) men, 52 (47.27%) women; average age 37.95 years (14-56) ± 10.60; most affected level: L4-L5 in 63 (57.14%) patients. NPS preoperative average: 7.75 (5-9) ± 1.12, and at 365 days: 2.14 (0-7) ± 2.37. The mean preoperative ODI was 37% (28%-40%) + 3.06, and at 365 days 9.52% (0%-40%) + 13.92. The prognosis (ODI) was good to 79 (71.81%) patients at 365 days, regular in 26 (23.63%) and poor in 5 (4.57%), corresponding respectively to patients with no, mild, moderate and severe disability. The Macnab criteria showed similar results (p = 0.00, 95% CI 0.00 to 0.13 - Student's t). Conclusions: The results were good at one-year follow-up (p = 0.00), demonstrating that the MPN is still a good option for lumbosciatic pain relief.

Does Adolescents’ Depressive Symptoms Increase the Possibility of Addictive Internet Gaming?: 1-year Follow up Study in Korea

2017 ◽  
Vol 41 (S1) ◽  
pp. S204-S204 ◽  
Author(s):  
S.J. Jo ◽  
H.W. Yim ◽  
J. Hyunsuk ◽  
K. Eunjin ◽  
S. Hye-Jung ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Self Control ◽  
Child Depression ◽  
Baseline Assessment ◽  
Observation Study ◽  
Internet Gaming ◽  
Child Depression Inventory ◽  
Competing Interest ◽  
One Year

IntroductionAdolescents’ Internet gaming disorders might influence on their social and psychological developmental tasks and physical health negatively. Depression is the commonly co-existed conditions with addictive Internet gaming, but not much research has been reported whether depressive symptoms would precede the addictive Internet gaming in this population.ObjectivesThis prospective observation study was performed to make clear whether adolescents’ depressive symptoms precede their addictive Internet gaming.AimsAdolescents’ 1-year incidence of the addictive Internet gaming was calculated, and test their depressive symptoms increase the incidence.MethodsIn Korea, whole students of the 1st grade in three middle schools were participated in this study. Baseline assessment of 508 students was performed via standardized self-reported questionnaire on May–June, 2015. Internet game use-elicited symptom screen (IGUESS) was used to addictive Internet gaming conditions. IGUESS is the 9-itemed DSM-5 diagnostic criteria-based instrument to screen high risk of Internet gaming disorders. Depressive symptoms was measured by Child Depression Inventory (CDI) group. One year after the baseline assessment, follow-up assessment was performed. Four hundred and forty-eight students have been participated in the 1-year check up without addictive Internet gaming at baseline.ResultsIn total, 4.7% of subjects had depressive symptoms at baseline, and incidence of addictive Internet gaming was 9.2%. After adjusted by sex, Internet game use per week, and self-control status, depressive symptoms of baseline increased the 1-year incidence of addictive Internet gaming significantly (OR = 3.5, P = 0.034).ConclusionsDepressive adolescents have higher possibility they could experience the addictive Internet gaming.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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