PS042 Risk Factors Associated with Hyperhomocysteinemia Besides Folate in a Chinese Community-Based Population

Global Heart ◽  
2016 ◽  
Vol 11 (2) ◽  
pp. e23
Author(s):  
F. Fan ◽  
J. JIa ◽  
X. Xu ◽  
X. Qin ◽  
Y. Yang ◽  
...  
2020 ◽  
Vol 48 (1) ◽  
Author(s):  
David Mukunya ◽  
Beatrice Odongkara ◽  
Thereza Piloya ◽  
Victoria Nankabirwa ◽  
Vincentina Achora ◽  
...  

Abstract Background Neonatal hypoglycemia is the most common endocrine abnormality in children, which is associated with increased morbidity and mortality. The burden and risk factors of neonatal hypoglycemia in rural communities in sub-Saharan Africa are unknown. Objective To determine the prevalence and risk factors for neonatal hypoglycemia in Lira District, Northern Uganda. Methods This was a community-based cross-sectional study, nested in a cluster randomized controlled trial designed to promote health facility births and newborn care practices in Lira District, Northern Uganda. This study recruited neonates born to mothers in the parent study. Random blood glucose was measured using an On Call® Plus glucometer (ACON Laboratories, Inc., 10125 Mesa Road, San Diego, CA, USA). We defined hypoglycemia as a blood glucose of < 47 mg/dl. To determine the factors associated with neonatal hypoglycemia, a multivariable linear regression mixed-effects model was used. Results We examined 1416 participants of mean age 3.1 days (standard deviation (SD) 2.1) and mean weight of 3.2 kg (SD 0.5). The mean neonatal blood glucose level was 81.6 mg/dl (SD 16.8). The prevalence of a blood glucose concentration of < 47 mg/dl was 2.2% (31/1416): 95% CI 1.2%, 3.9%. The risk factors for neonatal hypoglycemia were delayed breastfeeding initiation [adjusted mean difference, − 2.6; 95% CI, − 4.4, − 0.79] and child age of 3 days or less [adjusted mean, − 12.2; 95% CI, − 14.0, − 10.4]. Conclusion The incidence of neonatal hypoglycemia was low in this community and was predicted by delay in initiating breastfeeding and a child age of 3 days or less. We therefore suggest targeted screening and management of neonatal hypoglycemia among neonates before 3 days of age and those who are delayed in the onset of breastfeeding.


Viruses ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 926
Author(s):  
Raquel Silva do Nascimento ◽  
Karen Lorena N. Baia ◽  
Samara Borges de Souza ◽  
Guilherme Martins G. Fontoura ◽  
Patrícia Ferreira Nunes ◽  
...  

People who use crack-cocaine (PWUCC) have numerous vulnerabilities and pose a challenge to health and social assistance services. The exposure to pathogens and risk situations occur differently according to each individual, region and social group. This study identified the presence, genotypes and factors associated with hepatitis E virus (HEV) exposure among a community-recruited cohort of 437 PWUCC in northern Brazil. Epidemiological information was collected through community-based assessments and interviews. Thereafter, blood and fecal samples were collected and tested for HEV using an immunoenzymatic assay, and the genotype was identified by PCR. Logistic regressions were used to identify the risk factors independently associated with exposure to HEV. In total, 79 (18.1%) PWUCC were exposed to HEV: 73 (16.7%) for IgG and six for IgG + IgM. HEV RNA was detected in six fecal samples and in two blood samples from PWUCC with IgM + IgG. Subtype 3c was identified in all of the samples. The factors associated with exposure to HEV were low monthly income, unstable housing (e.g., homelessness), crack-cocaine use ≥40 months, and the shared use of crack-cocaine equipment. The current study provides unique initial insights into HEV status and risk factors among PWUCC in a remote area in Brazil, with diverse implications for urgently improved diagnosis, prevention, and treatment intervention needs.


2020 ◽  
pp. injuryprev-2020-043874
Author(s):  
Jannelene Killops ◽  
Nicola Ann Sewry ◽  
Martin Schwellnus ◽  
Sonja Swanevelder ◽  
Dina Janse van Rensburg ◽  
...  

BackgroundThere are limited data on acute injury-related medical encounters (injuries) in endurance cycling events.ObjectiveTo determine the risk factors for injuries during a mass community-based endurance cycling event.DesignRetrospective, cross-sectional study.SettingCape Town Cycle Tour (109 km), South Africa.Participants102 251 race starters.MethodsAll injuries for 3 years were recorded by race medical doctors and nurses. Injuries were grouped into main anatomical area of injury, and a Poisson regression model was used to determine the risk factors associated with injuries.ResultsThe four injury risk factors associated with all injuries during an endurance cycling event were sex (women vs men, p<0.0001), older age (p=0.0005), faster cycling speed (p<0.0001) and higher average individualised Wind Speed (aiWindSpeed, p<0.0001). The only risk factor for serious/life-threatening injuries was women (p=0.0413). For specific main anatomical areas: head/neck (women), upper limb (women, older age, faster cyclists), trunk (women, higher aiWindSpeed), and lower limb (higher aiWindSpeed).ConclusionWomen, older age, faster cycling speed and higher aiWindSpeed were all risk factors for acute injuries during a mass community-based endurance cycling event. These risk factors should help inform race organisers and medical teams on race day to ensure the best medical care is given, and effective acute injury prevention programmes are disseminated.


2013 ◽  
Vol 13 (1) ◽  
Author(s):  
Magdalena-Isabel Rosell-Murphy ◽  
Rafael Abós-Herràndiz ◽  
Josep Tarrés Olivella ◽  
Constança Alberti-Casas ◽  
Isabel García Allas ◽  
...  

2018 ◽  
Vol 7 (2) ◽  
pp. 4-8
Author(s):  
Shayla Amin ◽  
Nazrul Islam ◽  
ASM Ruhul Quddush ◽  
- Kamruzzaman ◽  
- Badruzzaman ◽  
...  

Umbilical hernia is one of the most commonly encountered abnormalities in early months of infancy and childhood. Though umbilical hernia is a common benign condition which resolves spontaneously during first 5 years of life, it may be a great concern to the parents and other caregivers. Therefore, the high index of suspicion, prompt recognition and thorough understanding of common factors are necessary to ensure their correction and convince the parents to treat. A hospital based cross sectional observational study was conducted in the paediatrics unit of Community Based Medical College & Hospital from March 2013 to September 2013 to determine the factors associated with umbilical hernia. A total of 160 cases of umbilical hernia admitted in paediatrics unit and outpatient department of Community Based Medical College & Hospital were enrolled in the study. Necessary information were collected by detailed history taking, clinical examination and close follow up of the hospital course, using pre-designed questionnaire. Among 160 patients, malnutrition were observed in 21.8% , severe malnutrition was the most common abnormality (45%) followed by moderate malnutrition 28.05%, mild malnutrition 28.05%. Low birth weight were found to have 21.3%, among medical condition, excessive crying were 18.7%, chronic cough were 18.7%, constipation were 17.5%, positive family history 1.9%. Malnutrition and low birth weight are more common association of umbilical hernia.Malnutrition has great impact on developing umbilical hernia. Chronic cough, excessive crying, constipation more or less equally responsible. So early identification of risk factors and proper management and close monitoring are important to reduce the risk of developing umbilical hernia. CBMJ 2018 July: Vol. 07 No. 02 P: 04-08


Author(s):  
Ashfaq Modiwala ◽  
Ajit Deshpande ◽  
R. R. Wavare ◽  
S. L. Kantharia

Background: Hypertension is growing rapidly to epidemic levels in the developing countries, that’s why described by some clinicians as a ‘silent killer’. The objective of the study was to study the prevalence of hypertension among adults in urban area of Indore city.Methods: A community based survey was conducted among the 375 residents of urban population of Indore.Results: In our study 157 subjects were found to be hypertensive with the prevalence of 41.9%. Where; new cases of hypertension were found to be with prevalence of 15.7%. Out of which males were 44 (20.3%). Whereas, previously diagnosed 98 (62.4%) subjects were on anti-hypertensive medication and 59 (37.6%) newly diagnosed subjects who did not know they were having hypertension.Conclusions: The prevalence of hypertension in study subjects was 41.9%. 15.7% subjects didn’t know that they were having hypertension. 31.6% of hypertensive subjects were on irregular medication. It was found that lack of awareness, negative attitude of people for practicing modifiable risk factors associated with hypertension.


Author(s):  
Eltagi A. M. Abdalla ◽  
Ragda F. Ahmed

Background: Diabetes mellitus is a major public health problem, affecting hundreds of millions of people worldwide. The objectives of the study were to estimate the prevalence of and to identify the possible risk factors associated with diabetes among the study population.Methods: A descriptive cross sectional community based study was carried out among 236 adults residing in Jabra area in Khartoum State in Sudan. Data were collected used pre tested structured questionnaire, and validated in a pilot study. The questionnaire included; socio-demographic data and possible risk factor such as (stress, physical exercise, history of pancreatic, history of renal problems and obesity). Anthropometric measurement included weight and height for BMI and laboratory data included random blood glucose (RBG) and fasting plasma glucose (FPG).Results: The present study showed, the prevalence of diabetes mellitus among adults in Jabra area was 18.6%. There was no significant sex difference in the prevalence rate. The results showed there was statistical association between diabetes positivity and marital status, age groups, educational level and family income p-values =(0.0002, 0.0004, 0.0005 and 0.0053) respectively. The multivariate analysis indicated family history of diabetes, obesity, physical activity, renal problems and pancreatic diseases were other risk factors associated with diabetes mellitus positivity OR =(2.19 (95% CI 1.10 - 4.34, p =0.027), 3.11 (95% CI 1.13 – 8.56, p =0.0278), 0.28 (95% CI 0.11 - 0.75, p =0.0113), 7.42 (95% CI 2.00- 27.57, p =0.0028) and 12.18 (95% CI 2.28 - 65.1, p =0.0035) respectively.Conclusions: The study found a higher prevalence of diabetes among study population. Risk factors showed a significant relation with higher fasting blood glucose.


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