The effects of chemical crosslinking manners on the physical properties and biocompatibility of collagen type I/hyaluronic acid composite hydrogels

2020 ◽  
Vol 160 ◽  
pp. 1201-1211 ◽  
Author(s):  
Weili Kong ◽  
Yongli Gao ◽  
Qingli Liu ◽  
Longpeng Dong ◽  
Likun Guo ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Physical Properties ◽  
Collagen Type ◽  
Collagen Type I ◽  
Type I ◽  
Chemical Crosslinking ◽  
Composite Hydrogels

Histologic Characterization of Rat Vocal Fold Scarring

2005 ◽  
Vol 114 (3) ◽  
pp. 183-191 ◽  
Author(s):  
Tomoko Tateya ◽  
Jin Ho Sohn ◽  
Ichiro Tateya ◽  
Diane M. Bless
Keyword(s):  
Hyaluronic Acid ◽  
Vocal Fold ◽  
Type I Collagen ◽  
Collagen Type ◽  
Control Level ◽  
Vocal Folds ◽  
Collagen Type I ◽  
Type I ◽  
Type Iii ◽  
Blue Stain

This study aimed to clarify the characteristics of rat vocal fold scarring by examining the alteration of key components in the extracellular matrix: hyaluronic acid, collagen, and fibronectin. Under monitoring with a 1.9-mm-diameter telescope, unilateral vocal fold stripping was performed, and larynges were harvested at 2, 4, 8, and 12 weeks after operation. The vocal folds were histologically analyzed with Alcian blue stain, trichrome stain, and immunofluorescence of collagen type I, collagen type III, and fibronectin. The scarred vocal folds showed less hyaluronic acid and more collagen types I and III than did the controls at all time points. Type III was stable for 12 weeks, while type I declined until 8 weeks and thereafter remained unchanged. Fibronectin increased for 4 weeks and then decreased; it was close to the control level at 8 and 12 weeks. These results suggest that the tissue remodeling process in scarred vocal folds slows down around 2 months after wounding.

A comparative study on collagen type I and hyaluronic acid dependent cell behavior for osteochondral tissue bioprinting

2014 ◽  
Vol 6 (3) ◽  
pp. 035004 ◽  
Author(s):  
Ju Young Park ◽  
Jong-Cheol Choi ◽  
Jin-Hyung Shim ◽  
Jung-Seob Lee ◽  
Hyoungjun Park ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Comparative Study ◽  
Collagen Type ◽  
Collagen Type I ◽  
Cell Behavior ◽  
Type I ◽  
Dependent Cell ◽  
Osteochondral Tissue

Biocompatibility study of modified injectable hyaluronic acid hydrogel with mannitol/BSA to alveolar bone cells

2020 ◽  
pp. 088532822097174
Author(s):  
Kwanhatai Areevijit ◽  
Nirada Dhanesuan ◽  
Jittima Amie Luckanagul ◽  
Sorasun Rungsiyanont
Keyword(s):  
Alkaline Phosphatase ◽  
Hyaluronic Acid ◽  
Collagen Type ◽  
Alveolar Bone ◽  
Bone Cells ◽  
Collagen Type I ◽  
Control Group ◽  
Type I ◽  
Hyaluronic Acid Hydrogel ◽  
Alveolar Bone Cells

The quality and quantity of bone are crucial to the success of dental implant treatment. Recently, bone grafting materials have reached some limitations. This study aimed to evaluate the biocompatibility of novel drug delivery material, injectable methacrylated hyaluronic acid hydrogel incorporated with different ratios of mannitol and BSA (Man/BSA MeHA), to human alveolar bone cells. The three-dimensionally encapsulated cell culture was evaluated with the resazurin cell viability test, alkaline phosphatase activity assay, immunohistochemistry test for collagen type-I synthesis, and cell morphology. The results showed that the encapsulated cells were viable in all four ratios of Man/BSA MeHA hydrogel and the average metabolic rate was not less than the control group. The morphology test showed round shape cells at the upper portion of the hydrogel and fibroblast-like or polygonal shape at the lower portion of hydrogel next to the culture plate. All four groups could express enzyme alkaline phosphatase and collagen type-I. In conclusion, four ratios of Man/BSA MeHA hydrogel were biocompatible with primary human alveolar bone cells.

scholarly journals Cranial Bone Regeneration with Collagen Type I and Polyvinylpyrrolidone (Fibroquel®) Combined with Hyaluronic Acid in Wistar Rats: Morphological Study

2021 ◽  
Vol 39 (3) ◽  
pp. 816-822
Author(s):  
Adolfo Soto-Domínguez ◽  
Gilberto Zatarain-Hernández ◽  
Rubén García-Garza ◽  
Lydia Enith Nava-Rivera ◽  
María de los Ángeles Pietschmann-Santamaría ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Bone Regeneration ◽  
Morphological Study ◽  
Wistar Rats ◽  
Collagen Type ◽  
Collagen Type I ◽  
Cranial Bone ◽  
Type I
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