scholarly journals Gestational outcomes in women infected by Zika virus during pregnancy in Mato Grosso do Sul, Brazil: A cross-sectional study

2020 ◽  
Vol 98 ◽  
pp. 359-365
Author(s):  
Iara Beatriz Andrade de Sousa ◽  
Cristina Souza ◽  
Marcelo dos Santos Barbosa ◽  
Julio Henrique Rosa Croda ◽  
Crhistinne Cavalheiro Maymone Gonçalves ◽  
...  
Keyword(s):  
Zika Virus ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Mato Grosso ◽  
Mato Grosso Do Sul

scholarly journals Aspectos clínicos e epidemiológicos relacionados ao transplante de córneas

2019 ◽  
Vol 13 ◽  
Author(s):  
Mayk Penze Cardoso ◽  
Marcos Antonio Ferreira Júnior ◽  
Elenilda De Andrade Pereira Gonçalves ◽  
Vanessa Giavarotti Taboza Flores ◽  
Élen Ferraz Teston ◽  
...  
Keyword(s):  
Health Services ◽  
Corneal Transplantation ◽  
Epidemiological Data ◽  
Distribution Patterns ◽  
Cross Sectional Study ◽  
The State ◽  
Cross Sectional ◽  
Mato Grosso ◽  
Eye Banks ◽  
Mato Grosso Do Sul

RESUMOObjetivo: caracterizar epidemiologicamente os transplantes de córneas realizados no estado de Mato Grosso do Sul. Método: trata-se de estudo quantitativo, epidemiológico, de desenho transversal. Compor-se-á a amostra de estudo de forma censitária por todos os pacientes em fila de espera, os submetidos ao transplante de córneas e os doadores desse tipo de tecido no Estado de Mato Grosso do Sul. Realizar-se-á a coleta de dados por meio de três instrumentos elaborados para cada população distinta, com as variáveis de dados clínicos e epidemiológicos. Estabelecer-se-ão estatisticamente os padrões de distribuição e as frequências, bem como as medidas de tendência central, além da análise multivariada com aplicação de medidas de magnitude de efeito e associação, de acordo com a natureza de cada variável, a serem apresentados em forma de gráficos e tabelas. Resultados esperados: espera-se identificar as dificuldades encontradas no sistema estadual de transplante de córneas com foco no desenvolvimento de conceitos técnicos, de planejamento e organização do atendimento aos usuários em fila de espera, doadores e transplantados. Descritores: Transplante de Córnea; Doenças da Córnea; Retalhos de Tecido Biológico; Epidemiologia; Serviços de Saúde; Bancos de Olhos.ABSTRACTObjective: to make the clinical and epidemiological characterization of corneal transplants performed in the state of Mato Grosso do Sul. Method: this is a quantitative, epidemiological, cross-sectional study. A sample of the study will be collected in a census form for all patients in queue, those submitted to corneal transplantation and donors of this type of tissue in the State of Mato Grosso do Sul. Data collection will be performed by means of three instruments elaborated for each distinct population, with the variables of clinical and epidemiological data. Distribution patterns and frequencies as well as measures of central tendency will be statistically established, as well as multivariate analysis with application of magnitude of effect and association, according to the nature of each variable, to be presented in charts and tables. Expected results: it is hoped to identify the difficulties found in the state transplant system of corneal aimed at the development of technical concepts, planning and organization of care for waiting users, donors and transplanted patients. Keywords: Corneal Transplantation; Corneal Diseases; Biological Tissue Patchwork; Epidemiology; Health services; Eye Banks. Descriptors: Corneal Transplantation; Corneal Diseases; Free Tissue Flaps; Epidemiology; Health Services; Eye Banks.RESUMENObjetivo: caracterizar epidemiológicamente los trasplantes de córneas hechos en el estado de Mato Grosso do Sul. Método: trata-se de un estudio cuantitativo, epidemiológico, de diseño transversal. La muestra de estudio se compondrá de forma censal por todos los pacientes en cola de espera, los sometidos al trasplante de córneas y los donantes de ese tipo de tejido en el Estado de Mato Grosso do Sul. Se realizará la recolección de datos mediante tres instrumentos preparados para cada población distinta, con las variables de datos clínicos y epidemiológicos. Se establecerán estadísticamente los patrones de distribución y las frecuencias, así como las medidas de tendencia central, además del análisis multivariado con aplicación de medidas de magnitud de efecto y asociación, de acuerdo con la naturaleza de cada variable, que deberán presentarse en forma de gráficos y tablas. Resultados esperados: se espera identificar las dificultades encontradas en el sistema estatal de trasplante de córneas mirando el desarrollo de conceptos técnicos, de planificación y organización de la atención a los usuarios en cola de espera, los donantes y los trasplantados. Descriptores: Trasplante de Córnea; Enfermedades de Córnea; Colgajos Tisulares Libres; Epidemiología; Servicios de Salud; Bancos de Ojos.

scholarly journals Pediatric neurodevelopment by prenatal Zika virus exposure: A cross-sectional study of the Microcephaly Epidemic Research Group Cohort

2020 ◽  
Author(s):  
paula sobral Silva ◽  
Sophie Helena Eickmann ◽  
Ricardo Arraes de Alencar Ximenes ◽  
Ulisses Ramos Montarroyos ◽  
Marília de Carvalho Lima ◽  
...  
Keyword(s):  
At Risk ◽  
Zika Virus ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Early Assessment ◽  
Cross Sectional ◽  
Group 4 ◽  
Neurological Abnormalities ◽  
Development Delay ◽  
And Behavior

Abstract Background: The implications of congenital Zika Virus (ZIKV) infections for pediatric neurodevelopment and behavior remain inadequately studied. The aim of this study is to investigate patterns of neurodevelopment and behavior in children with different levels of ZIKV-related microcephaly or with prenatal ZIKV exposure in the absence of microcephaly. Methods: We conducted a cross-sectional study, nested in a cohort, of 274 children (aged 10-45 months) who were born during the peak and decline of the microcephaly epidemic in Northeast Brazil. Participants were evaluated between February 2017 and August 2019 at two tertiary care hospitals in Recife, Brazil. We analyzed the children in four groups assigned based on clinical and laboratory criteria: Group 1 had severe microcephaly; Group 2 had moderate microcephaly; Group 3 had prenatal ZIKVxposure confirmed by maternal RT-PCR testing and no microcephaly; and Group 4 was a neurotypical control group. Groups were evaluated clinically for neurological abnormalities and compared using the Survey of Wellbeing of Young Children (SWYC), a neurodevelopment and behavior screening instrument, and a SWYC adapted form to compare severe cases. Results: Based on the SWYC screening, we observed differences between the groups for developmental milestones but not behavior. Among children with severe microcephaly of whom 98.2% presented with neurological abnormalities, 99.1% were at risk of development delay, and presented similar performance whether evaluated under or over 24 months of age. Among children with moderate microcephaly of whom 60% presented with neurological abnormalities, 65% were at risk of development delay. For children without microcephaly, the percentages found to be at risk of developmental delays were markedly lower and did not differ by prenatal ZIKV exposure status: Groups 3, 13.8%; Group 4, 21.7%. Conclusions: Among groups of children with prenatal ZIKV exposure, we found a gradient of risk of development delay. Children with severe microcephaly were at highest risk, while normocephalic ZIKV-exposed children had similar risks to unexposed control children. We propose that ZIKV-exposed children should undergo first-line screening for neurodevelopment and behavior using the SWYC. Early assessment and follow-up will enable at-risk children to be referred to a more comprehensive developmental evaluation and to multidisciplinary care management.

scholarly journals Electronic cigarette awareness and use among students at the Federal University of Mato Grosso, Brazil

2018 ◽  
Vol 44 (5) ◽  
pp. 367-369 ◽  
Author(s):  
Wemerson José Corrêa de Oliveira ◽  
Alexandre Figueiredo Zobiole ◽  
Claudia Bonadiman de Lima ◽  
Rebeca Melo Zurita ◽  
Pedro Eduardo Muniz Flores ◽  
...  
Keyword(s):  
University Students ◽  
Parental Education ◽  
Cross Sectional Study ◽  
Electronic Cigarette ◽  
Work Status ◽  
Cigarette Use ◽  
Sectional Study ◽  
Cross Sectional ◽  
Mato Grosso ◽  
The Family

ABSTRACT Objective: To analyze the prevalence of electronic cigarette (e-cigarette) awareness and experimentation among university students, as well as the characteristics associated with that awareness. Methods: This was a cross-sectional study, conducted in 2015, in which 489 university students at the Federal University of Mato Grosso (Cuiabá campus), Brazil, were interviewed with the use of a specific questionnaire. We estimated the prevalence of e-cigarette awareness and use, as well as analyzing the major characteristics associated with that awareness and use. Results: The prevalence of e-cigarette awareness was 37%, and the rate of e-cigarette experimentation was 2.7%. Awareness of e-cigarettes was found to be associated with marital status, work status, the level of parental education, and the presence or absence of smokers in the family. Conclusions: A high proportion of university students were aware of e-cigarettes. Although the prevalence of those who had experimented with e-cigarettes was low, there is concern that there could be an increase in the use of these types of device. There is a need for measures targeting university students, in order to build awareness of and prevent e-cigarette use.

scholarly journals Pediatric neurodevelopment by prenatal Zika virus exposure: A cross-sectional study of the Microcephaly Epidemic Research Group Cohort

2020 ◽  
Author(s):  
Paula Fabiana Sobral Silva ◽  
Sophie Helena Eickmann ◽  
Ricardo Arraes de Alencar Ximenes ◽  
Ulisses Ramos Montarroyos ◽  
Marília de Carvalho Lima ◽  
...  
Keyword(s):  
At Risk ◽  
Zika Virus ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Group 4 ◽  
Neurological Abnormalities ◽  
Development Delay ◽  
Group 3 ◽  
And Behavior

Abstract Background: The implications of congenital Zika Virus (ZIKV) infections for pediatric neurodevelopment and behavior remain inadequately studied. The aim of this study is to investigate patterns of neurodevelopment and behavior in groups of children with differening severities of ZIKV-related microcephaly and children with prenatal ZIKV exposure in the absence of microcephaly.Methods: We conducted a cross-sectional study, nested in a cohort, of 274 children (aged 10-45 months) who were born during the peak and decline of the microcephaly epidemic in Northeast Brazil. Participants were evaluated between February 2017 and August 2019 at two tertiary care hospitals in Recife, Pernambuco, Brazil. We analyzed the children in four groups assigned based on clinical and laboratory criteria: Group 1 had severe microcephaly; Group 2 had moderate microcephaly; Group 3 had prenatal ZIKVexposure confirmed by maternal RT-PCR testing but no microcephaly; and Group 4 was a neurotypical control group. Groups were evaluated clinically for neurological abnormalities and compared using the Survey of Wellbeing of Young Children (SWYC), a neurodevelopment and behavior screening instrument validated for use in Brazil. Children with severe delays underwent further evaluation with an adapted version of the SWYC.Results: Based on the SWYC screening, we observed differences between the groups for developmental milestones but not behavior. Among the 114 children with severe microcephaly of whom 98.2% presented with neurological abnormalities, 99.1% were ‘at risk of development delay’ according to the SWYC instrument. Among the 20 children with moderate microcephaly of whom 60% presented with neurological abnormalities, 65% were ‘at risk of development delay’. For children without microcephaly, the percentages found to be ‘at risk of developmental delay’ were markedly lower and did not differ by prenatal ZIKV exposure status: Group 3 (N=94), 13.8%; Group 4 (N=46), 21.7%.Conclusions: Among children with prenatal ZIKV exposure, we found a gradient of risk of development delay according to head circumference. Children with severe microcephaly were at highest risk for delays, while normocephalic ZIKV-exposed children had similar risks to unexposed control children. We propose that ZIKV-exposed children should undergo first-line screening for neurodevelopment and behavior using the SWYC instrument. Early assessment and follow-up will enable at-risk children to be referred to a more comprehensive developmental evaluation and to multidisciplinary care management.

scholarly journals Prenatal follow-up of Haitian and Brazilian women in Mato Grosso

2018 ◽  
Vol 18 (2) ◽  
pp. 317-326
Author(s):  
Delma Riane Rebouças Batista ◽  
Silvia Angela Gugelmin ◽  
Ana Paula Muraro
Keyword(s):  
Cross Sectional Study ◽  
The State ◽  
Sectional Study ◽  
Cross Sectional ◽  
Mato Grosso ◽  
The Public ◽  
Live Births ◽  
Birth Characteristics ◽  
Birth Records

Abstract Objectives: to analyze the prenatal follow-up performed by pregnant women in Haiti and Brazil in the state of Mato Grosso. Methods: a cross-sectional study of secondary database, with analysis of SINASC birth records in Mato Grosso between 2013 and 2015, of Brazilian children, born from both Brazilian and Haitian mothers. Variables related to the identification of the newborn and the woman, maternal data on gestational history, including information on prenatal follow-up of the last gestation were evaluated, besides the birth characteristics. Results: 167,820 live births were registered in the state in the period, of which 139 (0.08%) were children of Haitian women. Haitian mothers were older, however with lower schooling when compared to Brazilian mothers. The proportion of mothers of Haitian nationality who had at least 6 prenatal consultations was lower, and the proportion of vaginal births was higher, when compared to Brazilian women. The prevalence of low birth weight among live births of Haitian mothers was also higher. Conclusions: the results of this study point to the need to understand these differences, since some indicators have distanced from those advocated by WHO. These findings may contribute to the public policies development aimed at this population.

scholarly journals 24-hour Holter findings in infants with in utero exposure to Zika virus: a cross-sectional study.

2019 ◽  
Author(s):  
Dulce Helena Gonçalves Orofino ◽  
Sonia Regina Lambert Passos ◽  
Sheila Moura Pone ◽  
Marcos Silva Pone ◽  
Elisa Barroso de Aguiar ◽  
...  
Keyword(s):  
Heart Rate ◽  
Zika Virus ◽  
Qt Interval ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Discharge Data ◽  
Whitney Test ◽  
Mann Whitney Test ◽  
Significant Difference

Abstract Background : Antenatal exposure to the Zika virus (ZIKV) is related to severe neurological, ophthalmological and orthopedic manifestations called congenital Zika syndrome (CZS), but no changes in the electrical activity of the heart have been found. A higher prevalence of structural cardiac changes has been described in CZS patients when compared to the general population of live births. To describe 24-hour Holter findings in infants with confirmed antenatal exposure to ZIKV. Methods : Cross-sectional study of 24-hour Holter findings in infants with antenatal exposure to ZIKV confirmed by positive polymerase chain reaction(PCR) . Patients of the cohort of newborns and infants exposed intrautero to the ZIKV which began in November 2015 and continues to date and were hospitalized for clinical or surgical reasons were included. The 24-hour Holter monitoring was performed the day before discharge. Data analysis was descriptive and included subgroups of patients according to the presence of CZS and severe microcephaly. Heart rate, ST segment, QT interval and arrhythmias were evaluated. To evaluate heart rate variability (HRV) we used time domain analysis. The Mann-Whitney test was performed to verify significant differences between the subgroups of patients. Results : The sample consisted of 15 infants with average age of 16 months and 12 were diagnosed with CZS (8 had severe microcephaly). PCR at birth was positive in 8 newborn and 7 had positive maternal PCR during pregnancy. No arrhythmias or QT interval changes were observed. The Mann-Whitney test showed a significant difference between patients with and without CZS and with and without severe microcephaly, with HRV being lower in the groups with severe microcephaly and CZS. Conclusions : The study suggests that the HRV evaluation can be used as a sentinel event to assess the possibility of progressive neurological impairment in newborns with antenatal exposure to ZIKV, allowing early initiation of stimulation therapies in addition to indicating that cardiovascular complications may arise in the medium and long term.

scholarly journals Vulnerabilidade à sífilis gestacional e congênita: uma análise de 11 anos [Vulnerability to gestational and congenital syphilis: a 11-year analysis] [Vulnerabilidad a la sífilis gestacional y congénita: un análisis de 11 años]

2020 ◽  
Vol 28 ◽  
pp. e50487
Author(s):  
Joice Élica Espindola Paes Ozelame ◽  
Oleci Pereira Frota ◽  
Marcos Antonio Ferreira Júnior ◽  
Elen Ferraz Teston
Keyword(s):  
Skin Color ◽  
Congenital Syphilis ◽  
Secondary Data ◽  
Cross Sectional Study ◽  
Vulnerable Groups ◽  
Related Factors ◽  
Cross Sectional ◽  
Mato Grosso ◽  
Disease Information ◽  
Mato Grosso Do Sul

Objetivo: analisar a ocorrência de sífilis gestacional e congênita à luz da vulnerabilidade, no período de 2008 a 2018, no Mato Grosso do Sul. Método: estudo transversal, retrospectivo, de caráter analítico e abordagem quantitativa, com base em dados secundários coletados no Sistema de Informações e Agravos de Notificação. Resultados: houve aumento progressivo de sífilis gestacional e congênita ao longo dos 11 anos, com predomínio em populações vulneráveis e associação (p<0,05) da ocorrência de sífilis congênita com as variáveis “escolaridade”, “faixa etária” e “cor da pele”. Verificou-se a influência de fatores comportamentais e relacionados aos serviços de saúde, dentre eles o diagnóstico tardio da sífilis e a baixa adesão do tratamento entre estas gestantes e seus parceiros sexuais. Conclusão: a sífilis gestacional e congênita tiveram causas multifatoriais e podem ser combatidas com ações em saúde que considerem os aspectos que potencializam a vulnerabilidade social, individual e programática da população.ABSTRACTObjective: to examine the occurrence of gestational and congenital syphilis in the light of vulnerability in Mato Grosso do Sul, from 2008 to 2018. Method: this retrospective, analytical, quantitative, cross-sectional study was based on secondary data collected from Brazil’s Notifiable Disease Information System. Results: gestational and congenital syphilis increased steadily over the eleven years, predominantly in vulnerable groups. The occurrence of congenital syphilis was found to associate (p < 0.05) with the variables “education”, “age group” and “skin color”. Behavioral and health service-related factors – among them, late diagnosis of syphilis and poor treatment adherence by pregnant women and their sexual partners – were found to influence the association. Conclusion: gestational and congenital syphilis had multifactorial causes and can be combated with health measures that address aspects that heighten this population’s social, individual and programmatic vulnerability.RESUMENObjetivo: examinar la ocurrencia de sífilis gestacional y congénita a la luz de la vulnerabilidad en Mato Grosso do Sul, de 2008 a 2018. Método: este estudio retrospectivo, analítico, cuantitativo y transversal se basó en datos secundarios recopilados del Sistema de Información de Enfermedades Notificables de Brasil. Resultados: la sífilis gestacional y congénita aumentó de manera sostenida durante los once años, predominantemente en grupos vulnerables. Se encontró que la ocurrencia de sífilis congénita se asocia (p <0.05) con las variables "educación", "grupo de edad" y "color de piel". Se encontró que factores relacionados con el comportamiento y los servicios de salud, entre ellos, el diagnóstico tardío de la sífilis y la mala adherencia al tratamiento por parte de las mujeres embarazadas y sus parejas sexuales, influyen en la asociación. Conclusión: la sífilis gestacional y congénita tuvo causas multifactoriales y se puede combatir con medidas de salud que aborden aspectos que aumentan la vulnerabilidad social, individual y programática de esta población.

Maternal and congenital infections arising from Zika, dengue and Chikungunya arboviruses in Salvador, Brazil

2019 ◽  
Vol 114 (3) ◽  
pp. 222-225
Author(s):  
Alan Oliveira Duarte ◽  
João Vitor Oliveira ◽  
Tereza Cristina Xavier Carvalho ◽  
Lorena de Brito Pessoa ◽  
Cláudio Magalhães Filho ◽  
...  
Keyword(s):  
Zika Virus ◽  
Neonatal Screening ◽  
Congenital Infection ◽  
Cross Sectional Study ◽  
Igg Antibodies ◽  
Sectional Study ◽  
Cross Sectional ◽  
High Exposure ◽  
Congenital Infections ◽  
Igm Antibodies

Abstract Background Salvador was one of the Brazilian cities most affected during the 2015 Zika virus (ZIKV) outbreak. Methods A cross-sectional study was performed with enrolment of parturients and their newborns. Results Positive IgM antibodies for ZIKV, dengue (DENV) and Chikungunya (CHIKV) were present in 6.9, 11.9 and 22.8% of the parturients, and IgG antibodies were detected in 72.3, 92.3 and 38.6%, respectively. No cases of DENV congenital infection were identified. ZIKV and CHIKV congenital infections were observed in 16.5 and 13% of newborns, respectively. Conclusions High exposure rates to the three arboviruses and the identification of newborns with ZIKV and CHIKV congenital infections reinforces the necessity of ZIKV and CHIKV prenatal and neonatal screening in endemic regions.

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