Involuntary sensory enhancement of gain- and loss-associated tones: A general relevance principle

2019 ◽  
Vol 138 ◽  
pp. 11-26
Author(s):  
Timea Folyi ◽  
Dirk Wentura
1985 ◽  
Vol 10 (2) ◽  
pp. 79-86 ◽  
Author(s):  
Anne Costigan ◽  
Frances E. Wood ◽  
David Bawden

A comparative evaluation of three implementations of a large databank, the NIOSH Registry of Toxic Effects of Chem ical Substances, has been carried out. The three implementa tions are: a printed index, a text searching computer system, and a computerised chemical databank system, with substruc ture searching facilities. Seven test queries were used, with the aim of drawing conclusions of general relevance to chemical databank searching. The computer systems were shown to have advantages over printed indexes for several of the queries, including those involving an element of browsing. Substructure search facilities were especially advantageous. Aspects of indexing of data present, and the criteria for inclusion of types of data, were also highlighted.


2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Arik Bergman ◽  
Robert Duggan ◽  
Kavita Sharma ◽  
Moshe Tur ◽  
Avi Zadok ◽  
...  

AbstractThe exotic physics emerging in non-Hermitian systems with balanced distributions of gain and loss has recently drawn a great deal of attention. These systems exhibit phase transitions and exceptional point singularities in their spectra, at which eigen-values and eigen-modes coalesce and the overall dimensionality is reduced. So far, these principles have been implemented at the expense of precise fabrication and tuning requirements, involving tailored nano-structured devices with controlled optical gain and loss. In this work, anti-parity-time symmetric phase transitions and exceptional point singularities are demonstrated in a single strand of single-mode telecommunication fibre, using a setup consisting of off-the-shelf components. Two propagating signals are amplified and coupled through stimulated Brillouin scattering, enabling exquisite control over the interaction-governing non-Hermitian parameters. Singular response to small-scale variations and topological features arising around the exceptional point are experimentally demonstrated with large precision, enabling robustly enhanced response to changes in Brillouin frequency shift.


2021 ◽  
Vol 13 (8) ◽  
pp. 4425
Author(s):  
Taewoo Kim

In this paper, I investigate the relationship between previous going-concern audit opinions and subsequent asymmetric timeliness in accounting. Using the time-series and price-based models and conservatism proxy, I find that firms with going-concern audit opinions subsequently report losses in a more timely manner than firms that did not receive going-concern audit opinions. Furthermore, I also find that firms exiting going-concern audit opinions are more likely to report losses rather than gains in a timely manner, compared to firms non-exiting from going-concern opinions. This study extends the prior research by exploring the association between going-concern opinions and accounting conservatism from the perspective of client firms—that is, how firms behave strategically and conservatively to bypass going-concern opinions, once the firms had received previous going-concern opinions.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Elise Payzan-LeNestour ◽  
Lionnel Pradier ◽  
James Doran ◽  
Gideon Nave ◽  
Bernard Balleine

AbstractResearch in the field of multisensory perception shows that what we hear can influence what we see in a wide range of perceptual tasks. It is however unknown whether this extends to the visual perception of risk, despite the importance of the question in many applied domains where properly assessing risk is crucial, starting with financial trading. To fill this knowledge gap, we ran interviews with professional traders and conducted three laboratory studies using judgments of financial asset risk as a testbed. We provide evidence that the presence of ambient sound impacts risk perception, possibly due to the combination of facilitatory and synesthetic effects of general relevance to the perception of risk in many species as well as humans. We discuss the implications of our findings for various applied domains (e.g., financial, medical, and military decision-making), and raise new questions for future research.


2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Ping Zhou ◽  
Lei Xiao ◽  
Xiaonan Xu

Abstract Background As a tumor-accelerating transcriptional factor, E2F transcription factor 7 (E2F7) was up-regulated in many forms of cancers. Nevertheless, little has been reported about the impacts of E2F7 on oral squamous cell carcinoma (OSCC). Here, we aimed to probe whether E2F7 had influences on OSCC and its potential mechanism. Methods The expression of E2F7 in OSCC tissues was analyzed using the data acquired from TCGA and ONCOMINE databases. E2F7 prognostic value in OSCC patients was analyzed utilizing TCGA database. The expression of E2F7 in OSCC cell lines was detected by qRT-PCR. Gain-and loss-function of E2F7 assays in TCA-83 and CAL27 cells were performed respectively to inquire the function of E2F7. Western blotting was applied to test the alternations of EMT-related markers. Results In OSCC tissues, E2F7 was highly expressed. Besides, high expression of E2F7 predicted worse prognosis in OSCC patients. Moreover, E2F7 was over-expressed in TCA-83, HSC-4 and CAL27 (all OSCC cell lines) cells relative to that in HNOK (a normal cell line) cells. Gain-and loss-function assays displayed that deficiency of E2F7 suppresses CAL27 cell growth, migration, invasion and E2F7 high-expression resulted in inverse outcomes in TCA-83 cells. Finally, we found that silencing of E2F7 facilitated E-cadherin protein expression level and reduced N-cadherin, Vimentin and Snail protein levels in CAL27 cells, whilst E2F7 high-expression exhibited the opposite effects in TCA-83 cells. Conclusions These outcomes indicated that E2F7 performs a carcinogenic role in OSCC, which provides a theoretical basis for the therapeutic strategies of OSCC.


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