scholarly journals Wound Healing Potential OF DODONAEA VISCOSA Extract Formulation IN Experimental Animals

Author(s):  
Naira Nayeem ◽  
Syed Mohammed Basheeruddin Asdaq ◽  
Abdulhakeem S. Alamri ◽  
Walaa F. Alsanie ◽  
Majid Alhomrani ◽  
...  
1971 ◽  
Vol 11 (5) ◽  
pp. 254-257 ◽  
Author(s):  
John D. Constable ◽  
Anthony P. Scapicchio ◽  
Betsy Opitz

2013 ◽  
Vol 1 ◽  
pp. 336-341
Author(s):  
Olesya Mokhova

In the context of the above properties of titaniumaquacompleхglycerosolvate and oxytocin we have studied their joint application in order to increase the efficiency of treatment of soft tissue wounds. In the investigation performed, 144 experimental animals (white rats) with simulated aseptic wounds were studied. This study will contribute to develop a new treatment for soft tissue wounds, based on the application of aquaglitserosolvatetitanium and oxytocin, examine and assess the effectiveness of aquaglitserosolvatetitanium and oxytocin in the treatment of experimental soft tissue wounds. To assess the process of wound healing in the experiment, methods of clinical, planimetric progressive examinations of wounds, as well as strength characteristics of the scar formed were used. One of the objective measures of wound healing is the study of changes in the area in the healing process. The wound area was calculated by the method of L. N. Popovoy (1942). On the basis of clinical and planimetric methods of investigation, it was found that the decrease in the wound area is significantly faster under the influence of oxytocin and titanium aquacomplexglycerosolvate. 


2021 ◽  
Vol 25 (2) ◽  
pp. 45-54
Author(s):  
Thu Soan Hoang ◽  
Tien Thang Vu ◽  
Thi Kim Lien Vu ◽  
Thi Kieu Van Bui ◽  
Hoang Phuong Thuy Vu ◽  
...  

Objectives: Evaluate the hemostasis and skin graft wound healing effect of autologous fibrin adhesive in experimental animals. Methods: experimental method, conducted on 6 rabbits to determine the role of fibrin glue in hemostasis, ability to heal skin graft in experimental rabbits through assessment of graft status: size, swelling, color, boundary between the puzzle piece and the surrounding skin. Results: 1/ Effective hemostasis: fibrin glue transplant: hemostasis time is 129.33±42.01 seconds, transplant time is 128.33±41.87 seconds; suture stitching: hemostasis time is 475.17±59.97 seconds, stitching time is 350.67±52.23 seconds. At times after 1 day, 3 days, 7 days, 10 days, 14 days, 20 days and 30 days there is an earlier phenomenon of wound healing, the flattened and scarred patch is more beautiful than the skin graft with sewing thread. Conclusions: Using autologous fibrin glue in skin grafting has the ability to stop bleeding, heal wounds and achieve better aesthetics than skin grafting with sutures.


2020 ◽  
Vol 21 (1&2) ◽  
pp. 173-175
Author(s):  
Devendra Singh

The present study was conducted with an objective to observe the wound healing capacity under the influence of alternating current (AC) and direct current (DC) fields. To fulfil the aim of the study rats and rabbits were taken as experimental animals. These animals were divided into two groups i.e. experimental and control. Equal strength of animals were taken in each of the groups. During the study period It was observed that the surface area of the DC stimulated wound healed faster in comparison to AC stimulated wound. It was also found that the volume of AC stimulated wound healed faster than DC stimulated wound. Eventually, it was observed that stimulated wound healed rapidly in experimental animals in comparison to control group.


Proceedings ◽  
2018 ◽  
Vol 2 (25) ◽  
pp. 1537
Author(s):  
Sibel Bayil Oğuzkan ◽  
Salih Tunç Kaya ◽  
Aziz Cesur ◽  
Bora Karagül ◽  
Serpil Uğraş ◽  
...  

In this study, the wound healing effect of ozonated hazelnut oil was investigated on 54 male Sprague-Dawley rats. 7 experimental groups were designed. A circular area with a diameter of approximately 2 cm on dorsal surface was drawn using a coin and full thickness of the marked area was cut approximately 3 cm away from the ears by sterile scissors and forceps. All oils were daily applied on wound surface of experimental animals in volume of 0.2 mLduring 15 days. In this study, statistical analysis of the data was performed using the SPSS 22.0 package program. Wounds of all experimental animals were photographed by a digital camera on days 0, 3, 6, 12 and 15 after wounding. Ozonated oil treated wounds had significantly higher than the other groups on the day 3 after wounding. There is a quantitatively healing is determined on 3 day on rats. It has been observed in the stability period that ozonated oils must be stored at a temperature below 4 °C. Vitamin E should be added as an additive in the medical use of ozonated hazelnut oil in wound healing.


2021 ◽  
Vol 10 (2) ◽  
pp. 189-199
Author(s):  
Irene Cristina Br Sembiring ◽  
Anak Agung Gede Wardhita ◽  
Anak Agung Ayu Mirah Adi

This study aims to determine the effect of Muntingia calabura‘s leaves extract ointment on the healing of cuts in the skin of hyperglycemic mice in terms of collagen density. This study used 24 male mice (Mus musculus) with alloxan induced hyperglycemia (150 mg/kg body weight) intraperitoneal. Skin incisions are made on the back using a scalpel with a length of ± 15 mm and a depth reaching the subcutaneous. The experimental animals were randomly divided into four treatments and each treatment consisted of six replications, namely the control was given a placebo, and the treatment of cherry leaf extract ointment with a concentration of 30%, 40%, and 50%. The process of wound healing was observed histopathological with collagen density parameters. Based on the results, there was an increase in collagen density in each treatment. The mean collagen density in treatment (T) 0% (T0) 0.60; at treatment 30% (T1) 0.73; at treatment 40% (T3) 1,46; at 50% treatment (T3) was 2.20. The results of the study through the Kruskal Wallis test stated that the cherry leaf extract ointment had a very significant effect on the healing of the incision wound of hyperglycemic mice as seen from the density of collagen. We conclude that the administration of 50% cherry leaf extract ointment is the most effective in accelerating the healing of the hyperlycemic mice incision wounds in terms of collagen density.


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