Phytic Acid: An Alternative Root Canal Chelating Agent

2015 ◽  
Vol 41 (2) ◽  
pp. 242-247 ◽  
Author(s):  
Mohannad Nassar ◽  
Noriko Hiraishi ◽  
Yukihiko Tamura ◽  
Masayuki Otsuki ◽  
Kazuhiro Aoki ◽  
...  
Keyword(s):  
Phytic Acid ◽  
Root Canal ◽  
Chelating Agent

scholarly journals Evaluation of the Action of Chelating Agents on the Microhardness of Superficial Layer of Root Canal Lumen Dentin

2014 ◽  
Vol 5 (2) ◽  
pp. 124-128
Author(s):  
Srinidhi Surya Raghavendra ◽  
Bandu Devrao Napte
Keyword(s):  
Root Canal ◽  
Chelating Agents ◽  
Chelating Agent ◽  
Superficial Layer ◽  
Time Data ◽  
Significance Level ◽  
Multiple Comparison Test ◽  
Significant Difference ◽  
Post Hoc ◽  
Better Than

ABSTRACT Aim To evaluate the effect of different chelating agents on the microhardness of the superficial dentin layer of the root canal lumen. Materials and methods Forty-two extracted single rooted teeth were instrumented, and the roots were longitudinally sectioned in a buccolingual direction to expose the entire canal extension. The specimens were randomly distributed in four groups according to the final irrigation: Glyde File Prep (Dentsply Maillefer, Ballaigues, Switzerland), RC Help (Prime Dental Pvt. Ltd, Mumbai, India), Endo Prep RC (Stedman Anabond, Chennai, India), Dolo Endogel (Prevest Denpro Ltd, Jammu, India). A standardized volume of 50 ml of each chelating agent was used for 5 minutes. Dentin microhardness was measured with a Knoop indenter under a 50 gm load and a 15 seconds dwell time. Data was analyzed statistically by one-way analysis of variance ANOVA and post hoc multiple-comparison test at 5% significance level. Results Statistically significant difference was detected among the chelating agents by one-way ANOVA. Glyde File Prep and Dolo Endogel chelating agents differed significantly (p < 0.0001) in reduction of dentin microhardness from RC help and Endo Prep RC. Conclusion Glyde File Prep and Dolo Endogel are significantly better than RC Help and Endo Prep RC in reducing dentin microhardness. How to cite this article Napte BD, Srinidhi SR. Evaluation of the Action of Chelating Agents on the Microhardness of Superficial Layer of Root Canal Lumen Dentin. World J Dent 2014;5(2):124-128.

scholarly journals Efficacy of etidronic acid, BioPure MTAD and SmearClear in removing calcium ions from the root canal: An in vitro study

2015 ◽  
Vol 09 (04) ◽  
pp. 523-528 ◽  
Author(s):  
Hemant Kumar Yadav ◽  
A. P. Tikku ◽  
Anil Chandra ◽  
Rakesh Kumar Yadav ◽  
Devendra Kumar Patel
Keyword(s):  
Atomic Absorption ◽  
Calcium Ions ◽  
Root Canal ◽  
In Vitro Study ◽  
Chelating Agent ◽  
Negative Control ◽  
Atomic Absorption Spectrophotometer ◽  
Etidronic Acid ◽  
Group I

ABSTRACT Objective: The purpose of this study was to quantify the amount of calcium ions removed from the root canal by etidronic acid (HEBP), BioPure MTAD, and SmearClear using atomic absorption spectrophotometer. Materials and Methods: Fifty (n = 50) freshly extracted human mandibular premolar teeth were collected and decoronated at the cementoenamel junction. The canals were prepared in a crown down fashion using the rotary system and copiously irrigated with 1.0% sodium hypochlorite. All specimens were rinsed with the deionized water. Based on the type of chelating agent used, the samples (n = 10) were randomly divided into five (four test and one negative control) groups. Accordingly, Group I - 9% HEBP, Group II - 18% HEBP, Group III - SmearClear, Group IV - BioPure MTAD, and Group V - normal Saline. Subsequent to irrigation, the solution was collected in a test tube and subjected to atomic absorption spectrophotometer for the quantification of calcium ions removed from the root canal. Results: The mean concentration of calcium ions removed from the root canal (mean ± standard deviation) in all groups (I–V) were 13.32 ± 0.54 μg/ml, 16.36 ± 0.27 μg/ml, 20.04 ± 0.24 μg/ml, 18.15 ± 0.39 μg/ml, and 8.74 ± 0.49 μg/ml, respectively. Conclusions: SmearClear was the most effective agent for the removal of calcium ions from the root canal. Hence, its combined use with an organic solvent can be recommended for efficient smear layer removal.

Self-assembled photoactive heterojunction phase gradient

2014 ◽  
Vol 2 (23) ◽  
pp. 8868-8874 ◽  
Author(s):  
G. Merle ◽  
D. C. Bassett ◽  
J. A. Finch ◽  
G. Demopoulos ◽  
J. E. Barralet
Keyword(s):  
Time Series ◽  
Organic Solvent ◽  
Phytic Acid ◽  
Chelating Agent ◽  
Photocurrent Density ◽  
Phase Gradient ◽  
Self Assembled

The plant derived chelating agent phytic acid was found to promote the aqueous formation of anatase. By then electrodepositing in an organic solvent the biphasic rutile–anatase mixture could be separated to form a graded heterojunction. A time series characterisation confirmed that a large increase in photocurrent density coincided with the appearance of anatase in the coating.

Phytic acid in legumes: a review of nutritional importance and hydrothermal processing effect on underutilised species

Food Research ◽  
2020 ◽  
Vol 5 (3) ◽  
pp. 22-28
Author(s):  
M.A. Ojo
Keyword(s):  
Phytic Acid ◽  
Health Benefit ◽  
Chelating Agent ◽  
Mineral Elements ◽  
Hydrothermal Processing ◽  
Naturally Occurring ◽  
Legume Seeds ◽  
Nutritional Importance ◽  
Hydrothermal Methods

Phytic acid (IP6), also known as inositol hexakisphosphate, a naturally occurring component of legume seeds, is traditionally regarded as an antinutrient. This report was aimed to provide information on hydrothermal processing effects and nutritional importance of phytic acid in legumes. As a strong chelating agent, phytic acid has the ability to form complexes with protein and mineral elements (e.g. Ca, Fe, Zn and Mg) and thus makes the nutrients unavailable for absorption and utilisation. Reduction of IP6 using soaking and hydrothermal methods enhances the bioavailability of protein and mineral elements. Low level of phytic acid in diets have some health benefit effects and thus classification of phytic acid as an antinutrient needs to be reconsidered.

scholarly journals Comparative Evaluation of the Efficacy of Newer Irrigating Solutions in the Removal of Smear Layer Using SEM

2021 ◽  
pp. 76-83
Author(s):  
Srivalli Podili ◽  
Parvataneni Krishna Prasad ◽  
T. B. V. G. Raju ◽  
Mahendra Varma Nadimpalli ◽  
Gowtam Dev Dondapati ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Phytic Acid ◽  
Root Canal ◽  
Comparative Evaluation ◽  
Smear Layer ◽  
Control Group ◽  
Layer Removal ◽  
Significant Difference ◽  
Conventional Irrigation ◽  
Scanning Electron

Aim: To compare the effect of EDTA, Phytic acid and Peracitic acid on smear layer removal by effective conventional irrigation. Materials and Methodology: A total of 50 extracted mandibular premolars were selected. The canals were instrumented by rotary system up to F2 ProTaper and irrigated with 3% NaOCL simultaneously, teeth were divided into 4 groups according to the final irrigants: 17% EDTA; 2.25% PERACITIC ACID; 1% Phytic Acid; and saline. The canals were irrigated with 25 guage side vented needles for 5 minutes. Specimens were examined under scanning electron microscopy (SEM). Smear layer removal was evaluated at coronal, middle and apical thirds of the root canal. The data is analyzed using the Kruskal-Wallis and Mann-Whitney U tests. Results: In this study, the control group that is normal saline (4.05 ± 1.06) showed very less amount of smear layer removal. The highest amount of smear layer removal was seen in the group with phytic acid followed by peracitic acid and sodium hypochlorite groups. The apical third showed significantly more smear layer than the coronal and middle thirds (p<0.05). No significant difference was found between the coronal and middle thirds in all experimental groups (p>0.05). Conclusion: 1% phytic acid was the most effective in removing the smear layer at each level of the root canal followed by 2.5% peracitic and 17% EDTA.

scholarly journals Antimicrobial Activity of Phytic Acid: An Emerging Agent in Endodontics

2021 ◽  
Vol 11 ◽  
Author(s):  
Rania Nassar ◽  
Mohannad Nassar ◽  
Morgana E. Vianna ◽  
Nerissa Naidoo ◽  
Fatma Alqutami ◽  
...  
Keyword(s):  
Phytic Acid ◽  
Contact Time ◽  
Membrane Filtration ◽  
Ethylenediaminetetraacetic Acid ◽  
Fluorescent Microscopy ◽  
Chelating Agent ◽  
Bactericidal Effect ◽  
Antibiofilm Activity ◽  
Filtration Method ◽  
Time Required

BackgroundPhytic acid (IP6) is a promising and emerging agent, and because of its unique structure and distinctive properties, it lends itself to several applications in dentistry. Recently, IP6 was proposed as a potential chelating agent in endodontics. However, there is limited knowledge regarding its antimicrobial and antibiofilm effectiveness. The aims of this study, were therefore to evaluate the antimicrobial and antibiofilm activities of IP6 against a range of microbial species and compare these with ethylenediaminetetraacetic acid (EDTA) and sodium hypochlorite (NaOCl). The contact time required for IP6 to exert its bactericidal effect on Enterococcus faecalis was also determined.MethodsThe inhibitory and biocidal activities of IP6, EDTA and NaOCl were assessed using a broth microdilution assay against 11 clinical and reference strains of bacteria and a reference strain of Candida albicans. The contact time required for various IP6 concentrations to eliminate planktonic cultures of E. faecalis was determined using a membrane filtration method according to BS-EN-1040:2005. IP6 bactericidal activity was also evaluated using fluorescent microscopy, and the antibiofilm activity of the test agents was also determined.ResultsIP6 was biocidal against all tested microorganisms. At concentrations of 0.5%, 1% and 2%, IP6 required 5 min to exert a bactericidal effect on E. faecalis, while 5% IP6 was bactericidal after 30 s. IP6 also eradicated biofilms of the tested microorganisms. In conclusion, IP6 had notable antimicrobial effects on planktonic and biofilm cultures and exhibited rapid bactericidal effects on E. faecalis. This research highlighted, for the first time the antimicrobial and antibiofilm properties of IP6, which could be exploited, not only in dental applications, but also other fields where novel strategies to counter antimicrobial resistance are required.

Preparation of Phytic Acid Modified Polyurethane Wet Spinning Fibers for Application in Pb2+ Adsorption

2019 ◽  
Vol 35 (4) ◽  
pp. 497-506 ◽  
Author(s):  
YINCHUN FANG ◽  
◽  
XINHUA LIU ◽  
XIAO WU ◽  
XUCHEN TAO ◽  
...  
Keyword(s):  
Phytic Acid ◽  
Wet Spinning
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