Three-dimensional radiographic assessment of the mandibular interforaminal donor site in different vertical facial growth types

2021 ◽  
Author(s):  
B. Husseini ◽  
G. Khoury ◽  
F. Riachi ◽  
N. Ghosn ◽  
N. Khoury ◽  
...  
Keyword(s):  
Donor Site ◽  
Three Dimensional ◽  
Radiographic Assessment ◽  
Facial Growth ◽  
Growth Types

Adipose Tissue-Derived Stromal Cells Grown in Three-Dimensional Aliginate Constructs Display a Chondrogenic Phenotype

2000 ◽  
Author(s):  
Geoffrey R. Erickson ◽  
Jeffrey M. Gimble ◽  
Dawn Franklin ◽  
Farshid Guilak
Keyword(s):  
Articular Cartilage ◽  
Stromal Cells ◽  
Cartilage Damage ◽  
Donor Site ◽  
Subcutaneous Fat ◽  
Three Dimensional ◽  
Current Therapy ◽  
Chondrogenic Potential ◽  
Adipose Derived Stromal Cells ◽  
Chondrogenic Phenotype

Abstract Articular cartilage is the connective tissue that lines the surfaces of diarthrodial joints in the human body. Because cartilage is avascular, aneural, and alymphatic, it has a limited capacity for repair. Techniques such as microfracture, transplantation of autologous cartilage, and allograft or xenograft transplantations have not proven fully effective in treating cartilage damage. Current therapy is focusing on cell-based treatments such as autologous chondrocyte transplantation [1,2]. However, this method faces several limitations, as the donor site can provide a limited number of cells and the harvesting procedure itself may cause significant local morbidity. The goal of this study was to examine the chondrogenic potential of an autologous source of undifferentiated stromal cells derived from subcutaneous fat. It has been shown that chondrocytes embedded in a three-dimensional matrix retain a differentiated phenotype and produce cartilage-associated proteins [3]. In addition, it has been shown that alginate or agarose can support the formation of an extracellular matrix over time [4,5]. The goal of this study was to examine the chondrogenic potential of adipose-derived stromal cells with the ultimate goal of developing a “tissue engineering” method to regenerate articular cartilage.

scholarly journals Surgical benefit of mandibular morphometric analysis: A new tool to standardize mandibular reconstruction

PLoS ONE ◽  
2020 ◽  
Vol 15 (11) ◽  
pp. e0240558
Author(s):  
Alice Prevost ◽  
Franck Delanoe ◽  
Zoé Cavallier ◽  
Samuel Muller ◽  
Raphael Lopez ◽  
...  
Keyword(s):  
Morphometric Analysis ◽  
Descriptive Analysis ◽  
Donor Site ◽  
Three Dimensional ◽  
Free Flaps ◽  
Reference Points ◽  
Mandibular Reconstruction ◽  
Gonial Angle ◽  
Custom Made ◽  
Cutting Guides

Purpose The gold-standard for reconstruction of large mandibular defects is the use of free flaps of vascularized autologous bone with the fibula as the preferred donor site. The use of "custom cutting guides" for this indication is becoming increasingly prevalent. But cost of the procedure averages around 2,500 dollars per patient excluding treatment and entails selection criteria. We think it is possible to standardize mandibular reconstructions from an anatomical mean. The objective of this study was to perform a mandibular morphometric analysis in order to obtain a set of "mean" measurements, which can be used by all surgeons interested in mandibular reconstruction. Methods We performed a morphometric analysis consisting of three-dimensional mandibular reconstructions of 30 men and 30 women. Several reference points were set and defined to evaluate specific lengths and angles of interest. We conducted an intra and inter-sexual descriptive analysis of measurements obtained. Results We did not identify any major intra-sexual differences within each group. The gonial angle is more open in women and the measurements characterizing the basilar contour are more prominent in men. We did not identify any differences in alveolar region parameters. Conclusion The results of this study constitute a morphological tool for surgeons, from bone graft to free flap. These results also confirm us that the use of «custom cutting guides» for mandibular reconstruction may be excessive. It is pertinent to examine the value of "custom made" mandibular reconstructions since the differences observed are of the order of millimeters.

The three-dimensional stable mandibular landmarks in patients between the ages of 12.5 to 17.1 years

2020 ◽  
Author(s):  
Gui Chen ◽  
Mona Al Awadi ◽  
David William Chambers ◽  
Manuel O Lagravère-Vich ◽  
Tianmin Xu ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Growth Period ◽  
Mandibular Canal ◽  
Mental Foramen ◽  
Three Dimensions ◽  
Head Orientation ◽  
Facial Growth ◽  
Linear Distance ◽  
The Right ◽  
Stable Structures

Abstract Background: With the aid of implants, Björk identified the two-dimensional mandibular stable structures in cephalogram during facial growth. However, we don't know the three-dimensional stable structures exactly. The purpose of this study was to identify the most stable mandibular landmarks in growing patients using three-dimensional images.Methods: The sample was comprised of two cone-beam computed tomography (CBCT) scans taken about 4.6 years apart in 20 growing patients between the ages of 12.5 (T1) to 17.1 years (T2). After head orientation, landmarks were located on the chin (Pog), internal symphysis (Points C, D and E), and mandibular canals, which included the mental foramina (MF and MFA) and mandibular foramina (MdF). The linear distance change between Point C and these landmarks was measured on each CBCT to test stability through time. The reliability of the suggested stable landmarks was also evaluated. Results: The total distance changes between Point C and points D, E, Pog, MF, and MFA were all less than 1.0 mm from T1 to T2. The reliability measures of these landmarks, which were measured by the Cronbach alpha, were above 0.94 in all three dimensions for each landmark. From T1 to T2, distance changes from Point C to the right and left mandibular foramina were respectively 3.39±3.29 mm and 3.03±2.83 mm. Conclusions: During a growth period that averaged 4.6-years, ranging from 11.2 to 19.8 years, the structures that appeared relatively stable and could be used in mandibular regional superimposition included Pog, landmarks on the inferior part of the internal symphysis, and the mental foramen. The centers of the mandibular foramina, the starting points of the mandibular canal, underwent significant changes in the transverse and sagittal dimensions.

3D Evaluation of the Relationship between Different Vertical Growth Patterns and Cranial Base Angulations

2020 ◽  
Author(s):  
Mehmet Ugurlu ◽  
Rıdvan Oksayan ◽  
Ibrahim Sevki Bayrakdar ◽  
Fatih Kahraman ◽  
Ilhan Metin Dagsuyu ◽  
...  
Keyword(s):  
Statistical Tests ◽  
Three Dimensional ◽  
Cranial Base ◽  
Growth Patterns ◽  
High Angle ◽  
Facial Growth ◽  
Vertical Growth ◽  
Study Results ◽  
Kolmogorov Smirnov ◽  
Normal Angle

Abstract Objectives This study aimed to compare cranial base angulations in subjects with high-angle, low-angle, and normal-angle vertical growth patterns using cone beam computed tomography (CBCT). Design This study is a retrospective clinical research. Settings This study was carried out at the Dentistry Faculty of Eskisehir Osmangazi University. Participants According to skeletal vertical face growth patterns, 78 subjects (48 females and 30 males, average age: 13.19 ± 1.73 years) were divided equally into three groups: high angle, low angle, and normal angle groups. Main Outcome Measures Cephalometric images were derived from CBCT, and patients were classified according to the SN-GoGn angle (sella-nasion, gonion gnathion angle). Sagittal, axial, and coronal cranial base angulations were measured in three-dimensional (3D) CBCT images. Data were analyzed using the Kolmogorov–Smirnov normality, Kruskal–Wallis, and Mann-Whitney U statistical tests. Results There were statistically significant differences between the low-angle and high-angle groups according to sagittal cranial base angulation parameters (p = 0.01). Conversely, there were no statistically significant differences between vertical facial growth patterns according to coronal and axial cranial angle variables (p > 0.05). Conclusion According to the study results, there were no effects of cranial base angulations in two planes (coronal and axial) on different vertical skeletal growth patterns. In the sagittal cranial base angulation parameter, the high-angle group showed greater angulation values than the low-angle group. CBCT may be helpful for evaluating, diagnosing, and predicting 3D cranial base differences.

scholarly journals Three-Dimensional Technology Applications in Maxillofacial Reconstructive Surgery: Current Surgical Implications

Nanomaterials ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 2523
Author(s):  
Yasmin Ghantous ◽  
Aysar Nashef ◽  
Aladdin Mohanna ◽  
Imad Abu-El-naaj
Keyword(s):  
3D Printing ◽  
Head And Neck ◽  
Donor Site ◽  
Maxillofacial Surgery ◽  
Three Dimensional ◽  
Oral And Maxillofacial Surgery ◽  
3D Technology ◽  
Printing Technology ◽  
Reconstructive Procedures ◽  
3D Printing Technology

Defects in the oral and maxillofacial (OMF) complex may lead to functional and esthetic impairment, aspiration, speech difficulty, and reduced quality of life. Reconstruction of such defects is considered one of the most challenging procedures in head and neck surgery. Transfer of different auto-grafts is still considered as the “gold standard” of regenerative and reconstructive procedures for OMF defects. However, harvesting of these grafts can lead to many complications including donor-site morbidity, extending of surgical time, incomplete healing of the donor site and others. Three-dimensional (3D) printing technology is an innovative technique that allows the fabrication of personalized implants and scaffolds that fit the precise anatomy of an individual’s defect and, therefore, has attracted significant attention during the last few decades, especially among head and neck surgeons. Here we discuss the most relevant applications of the 3D printing technology in the oral and maxillofacial surgery field. We further show different clinical examples of patients who were treated at our institute using the 3D technology and discuss the indications, different technologies, complications, and their clinical outcomes. We demonstrate that 3D technology may provide a powerful tool used for reconstruction of various OMF defects, enabling optimal clinical results in the suitable cases.

scholarly journals Bone-Forming Capabilities of a Newly Developed NanoHA Composite Alloplast Infused with Collagen: A Pilot Study in the Sheep Mandible

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Charles Marin ◽  
Ryo Jimbo ◽  
Fabio Cesar Lorenzoni ◽  
Lukasz Witek ◽  
Hellen Teixeira ◽  
...  
Keyword(s):  
Bone Ingrowth ◽  
Donor Site ◽  
Three Dimensional ◽  
Polyglycolic Acid ◽  
Autogenous Bone ◽  
Graft Material ◽  
Resorption Rate ◽  
Experimental Block ◽  
The Status

Lateral or vertical bone augmentation has always been a challenge, since the site is exposed to constant pressure from the soft tissue, and blood supply only exists from the donor site. Although, for such clinical cases, onlay grafting with autogenous bone is commonly selected, the invasiveness of the secondary surgical site and the relatively fast resorption rate have been reported as a drawback, which motivated the investigation of alternative approaches. This study evaluated the bone-forming capability of a novel nanoHA alloplast infused with collagen graft material made from biodegradable polylactic acid/polyglycolic acid versus a control graft material with the same synthesized alloplast without the nanoHA component and collagen infiltration. The status of newly formed bone and the resorption of the graft material were evaluated at 6 weeksin vivohistologically and three dimensionally by means of 3D microcomputed tomography. The histologic observation showed that newly formed bone ingrowth and internal resorption of the block were observed for the experimental blocks, whereas for the control blocks less bone ingrowth occurred along with lower resorption rate of the block material. The three-dimensional observation indicated that the experimental block maintained the external geometry, but at the same time successfully altered the graft material into bone. It is suggested that the combination of numerous factors contributed to the bone ingrowth and the novel development could be an alternative bone grafting choice.

scholarly journals Sole Reconstruction Using Anterolateral Thigh Free Flap: A Review of 4 Cases

1970 ◽  
Vol 2 (3) ◽  
Author(s):  
Parintosa Atmodiwirjo ◽  
Afriyanti Sandhi
Keyword(s):  
Free Flap ◽  
Weight Bearing ◽  
Donor Site ◽  
Three Dimensional ◽  
Free Flaps ◽  
Donor Site Morbidity ◽  
Common Procedure ◽  
Anterolateral Thigh ◽  
Protective Sensation ◽  
And Function

Background: The ideal technique for sole reconstruction should meet such requisite as a durable and comfortable weight-bearing surface, solid anchoring to deep tissue for resistance to shear force and adequate protective sensation. The anterolateral thigh (ALT) perforator free flap provides a large, pliable skin island and sufficient bulk, allowing three-dimensional tailoring to complex defects. The present article is about our experience of sole reconstruction ALT perforator free flap. Patient and Method: Total of 4 flaps in the foot defects was performed in February 2009 to December 2012. We reconstructed soft tissue defects in the sole using ALT free flaps, the complications, aesthetic and function results were monitored. Result: ALT perforator free flap provided stable and durable long-term wound cover in all patients, resulting in early rehabilitation and function outcomes were completely achieved. Complications were few and manageable in all cases. Summary: ALT perforator free flap has become common procedure in many centers around the world. The numerous advantages include stable wound coverage; improve aesthetic and functional outcomes, and minimal donor site morbidity. In our experiences, we found that the use of ALT perforator free flap in sole defect reconstruction, to be technically affordable, reliable and have resulted in excellent outcomes.

scholarly journals One injection for a great projection: a quick and simple procedure for nipple reconstruction

2021 ◽  
Vol 48 (2) ◽  
pp. 179-184
Author(s):  
Sara Tanini ◽  
Sara Calabrese ◽  
Elena Lucattelli ◽  
Giulia Lo Russo
Keyword(s):  
Simple Procedure ◽  
Donor Site ◽  
Three Dimensional ◽  
Donor Site Morbidity ◽  
Single Step ◽  
Nipple Reconstruction ◽  
Breast Cancer Patients ◽  
Reconstruction Process ◽  
Areolar Complex ◽  
Wound Matrix

Women attach great importance to the presence of a three-dimensional nipple upon completion of the breast reconstruction process. To meet patients’ expectations, nipple-areolar complex reconstruction should achieve symmetry in position, size, shape, texture, and color, as well as minimizing donor-site morbidity. However, it is well known that regardless of the reconstructive technique, loss of nipple projection can be reasonably expected. We developed and evaluated a quick, simple, and innovative technique using injectable Integra Flowable Wound Matrix to increase nipple projection after reconstruction. Twenty breast cancer patients who underwent nipple reconstruction resulting in unsatisfactory projection were enrolled in our retrospective study. Nipple projection was measured at the time of surgery and after 6 and 12 months. A visual analogue scale was used to assess patients’ satisfaction. Our technique yielded reliable results in terms of the long-lasting maintenance of nipple projection. This method is high-priced, but cost-effective, since one kit may suffice for three patients. Furthermore, our patients were very appreciative of this technique as a single-step, minimally invasive, painless procedure with no reported necessity of re-intervention.

scholarly journals Application of modern 3d image acquisition systems to the morphological analysis of faces: a novel approach for the assessment of facial growth

2020 ◽  
Vol 7 (4) ◽  
pp. 268-273
Author(s):  
Gibelli Daniele Maria ◽  
◽  
Poppa Pasquale ◽  
Cappella Annalisa ◽  
Rosati Riccardo ◽  
...  
Keyword(s):  
Morphological Analysis ◽  
Three Dimensional ◽  
Laser Scanner ◽  
3D Models ◽  
Point Of View ◽  
Topographic Map ◽  
Facial Growth ◽  
General Increase ◽  
Novel Approach ◽  
Point To Point

Introduction The assessment of facial growth has always had a relevant importance in anatomy and morphological sciences. This article aims at presenting a method of facial superimposition between 3D models which provides a topographic map of those facial areas modified by growth. Methodology Eight children aged between 6 and 10 years were recruited. In December 2010 they underwent a 3D scan by the Vivid 910 laser scanner (Konica Minolta, Osaka, Japan). The same procedures were performed another five times, in June 2011, September 2011, January 2012 and September 2012; in total 6 analyses were performed on the same subjects in a time span of 21 months. Three-dimensional digital models belonging to the same individual were then superimposed on each other according to 11 facial landmarks. Three comparisons were performed for each individual, referring to the period between December 2010 and June 2011, between June 2011 and January 2012 and between January and September 2012. Results Results show that the protocol of superimposition gives a reliable image of facial growth with high sensibility: in detail, even the slight facial modifications due to different expressions are recorded. The method can also quantify the point-to-point difference between the two models, and therefore give an indication concerning the general increase or decrease of facial volume. Conclusion This approach may provide useful indications for the analysis of facial growth on a large sample and give a new point of view of the complex field of face development.

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