scholarly journals Biomechanical analysis of the camelid cervical intervertebral disc

2015 ◽  
Vol 3 (1) ◽  
pp. 34-43 ◽  
Author(s):  
Dean K. Stolworthy ◽  
R. Amy Fullwood ◽  
Tyler M. Merrell ◽  
Laura C. Bridgewater ◽  
Anton E. Bowden
Keyword(s):  
Intervertebral Disc ◽  
Biomechanical Analysis

scholarly journals In vivo intervertebral disc deformation: intratissue strain patterns within adjacent discs during flexion–extension

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Robert L. Wilson ◽  
Leah Bowen ◽  
Woong Kim ◽  
Luyao Cai ◽  
Stephanie Ellyse Schneider ◽  
...  
Keyword(s):  
Intervertebral Disc ◽  
Biomechanical Analysis ◽  
Resonance Imaging ◽  
Tissue Architecture ◽  
Mechanical Responses ◽  
Flexion Extension ◽  
Adjacent Disc ◽  
Shear Strains ◽  
Magnetic Resonance Imaging Mri

AbstractThe biomechanical function of the intervertebral disc (IVD) is a critical indicator of tissue health and pathology. The mechanical responses (displacements, strain) of the IVD to physiologic movement can be spatially complex and depend on tissue architecture, consisting of distinct compositional regions and integrity; however, IVD biomechanics are predominately uncharacterized in vivo. Here, we measured voxel-level displacement and strain patterns in adjacent IVDs in vivo by coupling magnetic resonance imaging (MRI) with cyclic motion of the cervical spine. Across adjacent disc segments, cervical flexion–extension of 10° resulted in first principal and maximum shear strains approaching 10%. Intratissue spatial analysis of the cervical IVDs, not possible with conventional techniques, revealed elevated maximum shear strains located in the posterior disc (nucleus pulposus) regions. IVD structure, based on relaxometric patterns of T2 and T1ρ images, did not correlate spatially with functional metrics of strain. Our approach enables a comprehensive IVD biomechanical analysis of voxel-level, intratissue strain patterns in adjacent discs in vivo, which are largely independent of MRI relaxometry. The spatial mapping of IVD biomechanics in vivo provides a functional assessment of adjacent IVDs in subjects, and provides foundational biomarkers for elastography, differentiation of disease state, and evaluation of treatment efficacy.

scholarly journals Development of a Detailed Volumetric Finite Element Model of the Spine to Simulate Surgical Correction of Spinal Deformities

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Mark Driscoll ◽  
Jean-Marc Mac-Thiong ◽  
Hubert Labelle ◽  
Stefan Parent
Keyword(s):  
Finite Element ◽  
Intervertebral Disc ◽  
Finite Element Model ◽  
Ex Vivo ◽  
Spinal Instrumentation ◽  
Element Model ◽  
Patient Data ◽  
Biomechanical Analysis ◽  
Published Data

A large spectrum of medical devices exists; it aims to correct deformities associated with spinal disorders. The development of a detailed volumetric finite element model of the osteoligamentous spine would serve as a valuable tool to assess, compare, and optimize spinal devices. Thus the purpose of the study was to develop and initiate validation of a detailed osteoligamentous finite element model of the spine with simulated correction from spinal instrumentation. A finite element of the spine from T1 to L5 was developed using properties and geometry from the published literature and patient data. Spinal instrumentation, consisting of segmental translation of a scoliotic spine, was emulated. Postoperative patient and relevant published data of intervertebral disc stress, screw/vertebra pullout forces, and spinal profiles was used to evaluate the models validity. Intervertebral disc and vertebral reaction stresses respected publishedin vivo,ex vivo, andin silicovalues. Screw/vertebra reaction forces agreed with accepted pullout threshold values. Cobb angle measurements of spinal deformity following simulated surgical instrumentation corroborated with patient data. This computational biomechanical analysis validated a detailed volumetric spine model. Future studies seek to exploit the model to explore the performance of corrective spinal devices.

scholarly journals The influence of the nucleus pulposus on the stress distribution in the natural and prosthetic intervertebral disc

2019 ◽  
Vol 252 ◽  
pp. 07006 ◽  
Author(s):  
Robert Karpiński ◽  
Łukasz Jaworski ◽  
Józef Jonak ◽  
Przemysław Krakowski
Keyword(s):  
Stress Distribution ◽  
Intervertebral Disc ◽  
Nucleus Pulposus ◽  
Inner Core ◽  
Lumbar Vertebrae ◽  
Fem Analysis ◽  
3D Models ◽  
Intervertebral Discs ◽  
Biomechanical Analysis ◽  
Lumbar Intervertebral Disc

The aim of this article was to present the results of a preliminary study on the stress distribution in the lumbar intervertebral disc [IVD] under loads induced during daily activities. Basic anatomy, biomechanical analysis of the vertebra and intervertebral disc were introduced. The third and fourth lumbar vertebrae were chosen for the study because they carry considerably higher loads, especially while standing or sitting. The static mechanical analyses using the finite element method (FEM) were conducted for four standard loads reflecting patient’s positions: recumbent, standing, sitting and standing with additional loads, and three models: an intervertebral disc with an inner nucleus pulposus and two prosthetic intervertebral discs, with or without an artificial nucleus. The FEM analysis was performed in the SolidWorks Simulation module on reverse-engineered 3D models of vertebrae and the intervertebral disc, based on a series of computed tomography [CT] scans of the patient’s spine, which had been properly processed in Materialise Mimics software and exported to CAD files. The model of the fourth intervertebral disc, placed between third and fourth vertebra, had been additionally modified to include its inner core, the nucleus pulposus.

scholarly journals A biomechanical analysis of four anterior cervical techniques to treating multilevel cervical spondylotic myelopathy: a finite element study

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Zhonghai Li ◽  
Hui Liu ◽  
Ming Yang ◽  
Wentao Zhang
Keyword(s):  
Intervertebral Disc ◽  
Cervical Spondylotic Myelopathy ◽  
Intervertebral Discs ◽  
Biomechanical Analysis ◽  
Adjacent Segment ◽  
Titanium Plate ◽  
Cage Subsidence ◽  
Adjacent Disc ◽  
Multilevel Cervical Spondylotic Myelopathy ◽  
Adjacent Segments

Abstract Background The decision to treat multilevel cervical spondylotic myelopathy (MCSM) remains controversial. The purpose of this study is to compare the biomechanical characteristics of the intervertebral discs at the adjacent segments and internal fixation, and to provide scientific experimental evidence for surgical treatment of MCSM. Methods An intact C2-C7 cervical spine model was developed and validated. Four additional models were developed from the fusion model, including multilevel anterior cervical discectomy and fusion (mACDF), anterior cervical corpectomy and fusion (ACCF), hybrid decompression and fusion (HDF), and mACDF with cage alone (mACDF-CA). Biomechanical characteristics on the plate and the disc of adjacent levels (C2/3, C6/7) were comparatively analyzed. Results Of the four models, stress on the upper (C2/3) adjacent intervertebral disc was the lowest in the mACDF-CA group and highest in the ACCF group. Stress on the intervertebral discs at adjacent segments was higher for the upper C2/3 than the lower C6/7 intervertebral disc. In all models, the mACDF-CA group had the lowest stress on the intervertebral disc, while the ACCF group had the highest stress. In the three surgical models with titanium plate fixation (mACDF, ACCF, and HDF), the ACCF group had the highest stress at the titanium plate-screw interface, while the mACDF group had the lowest stress. Conclusion Among the four anterior cervical reconstructive techniques for MCSM, mACDF-CA makes little effect on the adjacent disc stress, which might reduce the incidence of adjacent segment degeneration (ASD) after fusion. However, the accompanying risk of the increased incidence of cage subsidence should never be neglected.

scholarly journals The biological basis of degenerative disc disease: proteomic and biomechanical analysis of the canine intervertebral disc

2015 ◽  
Vol 17 (1) ◽  
Author(s):  
William Mark Erwin ◽  
Leroi DeSouza ◽  
Martha Funabashi ◽  
Greg Kawchuk ◽  
Muhammad Zia Karim ◽  
...  
Keyword(s):  
Intervertebral Disc ◽  
Degenerative Disc Disease ◽  
Biomechanical Analysis ◽  
Disc Disease ◽  
Biological Basis ◽  
Degenerative Disc

scholarly journals Biomechanical Analysis Of The Intervertebral Disc Implant Using The Finite Element Method

2015 ◽  
Vol 15 (3) ◽  
pp. 57-66
Author(s):  
W. Kajzer ◽  
A. Kajzer ◽  
I. Pindycki
Keyword(s):  
Finite Element Method ◽  
Finite Element ◽  
Intervertebral Disc ◽  
Vertebral Column ◽  
Motor Vehicle ◽  
Biomechanical Analysis ◽  
The Finite Element Method ◽  
Starting Point ◽  
Locomotive Activity ◽  
Element Method

Abstract Dysfunctions of the vertebral column belong to a group of civilisation diseases and they affect approximately 80% of population. The underlying cause is modern (sedentary) lifestyle, low locomotive activity of people and frequent motor vehicle and sports accidents. Despite civilisation’s progress, no injury prophylactics or prevention of dysfunctions of the vertebral column have been introduced. The key element influencing function of the vertebral column is the intervertebral disc. It enables multidimensional movements and constitutes a basic connective element between the joints of the vertebral column. It also enables performing basic daily activities. Acting as a “damper”, it cushions vibrations and transmits loads between the vertebrae. One of the diseases affecting the intervertebral disc is discopathy. This is the most common degenerative disease, which can be treated by both conservative and surgical treatment. After removal of the damaged disc, it can be replaced by an adequate implant, which will assume its function. The implant will be expected to restore the vertebral column motor function, as well as to eliminate the pain resulting from compression of the spine caused by the damaged disc. This paper presents a biomechanical analysis using the finite element method for the L2-L3 vertebrae system with natural intervertebral disc, and the L2-L3 – implant of the intervertebral disc system. Two cases of the system vertebrae-implant were analysed which differed in the placement of the artificial disc in the intervertebral space. Within the conducted analysis, the state of displacement, strain and stress of reduced analysed systems and their individual elements was determined. A comparative analysis of the results and calculations was performed, also conclusions and observations were formulated, constituting a starting point for building more advanced calculation models and further analyses of such implants.

Biomechanical analysis of degenerative intervertebral disc enlargement of human spine

2021 ◽  
pp. 1-16
Author(s):  
Yu Hui ◽  
Ze-xun Zhou ◽  
Xue-qiang Ren ◽  
Jing Du ◽  
Jian-Bin Yang ◽  
...  
Keyword(s):  
Intervertebral Disc ◽  
Biomechanical Analysis ◽  
Human Spine

scholarly journals Clinical Efficacy and Safety of “Three-Dimensional Balanced Manipulation” in the Treatment of Cervical Spondylotic Radiculopathy by Finite Element Analysis

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Shengnan Cao ◽  
Yuanzhen Chen ◽  
Feng Zhang ◽  
Shifei Sun ◽  
Congan Wang ◽  
...  
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Treatment Group ◽  
Intervertebral Disc ◽  
Three Dimensional ◽  
Element Model ◽  
Biomechanical Analysis ◽  
Control Group ◽  
Element Analysis ◽  
Cervical Spondylotic Radiculopathy

Cervical spondylotic radiculopathy (CSR) is the most commonly encountered cervical spine disorder. Cervical manipulation has been demonstrated as an effective therapy for patients. However, the mechanisms of manipulations have not been elucidated. A total of 120 cervical spondylotic radiculopathy patients were divided into the “three-dimensional balanced manipulation” treatment group (TBM group) and control group randomly. The control group was treated with traditional massage; the TBM treatment group was treated with “three-dimensional balanced manipulation” based on traditional massage. The symptoms and clinical efficacy of the patients were compared before and after treatment for one month. A three-dimensional finite element model was established. The mechanical parameters were imported to simulate TBM, and finite element analysis was performed. The results showed that the total effective rate was significantly higher in the TBM group compared with the control group. The biomechanical analysis showed the vertebral body stress was mainly distributed in the C3/4 spinous processes; the deformation mainly concentrated in the anterior processes of the C3 vertebral body. The intervertebral disc stress in the C3~C7 segment was mainly distributed in the anterior part of the C3/4 intervertebral disc, and the deformation extends to the posterior part of the C3/4 nucleus pulposus. In summary, these data are suggesting that TBM was effective in CSR treatment. The results of the finite element model and biomechanical analysis provide an important foundation for effectively avoiding iatrogenic injuries and improving the effect of TBM in the treatment of CSR patients.

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