A phenotype-structured model to reproduce the avascular growth of a tumor and its interaction with the surrounding environment

2021 ◽  
pp. 110980
Author(s):  
Giada Fiandaca ◽  
Sara Bernardi ◽  
Marco Scianna ◽  
Marcello Edoardo Delitala
Author(s):  
Saputri Rizki Ramadhanti ◽  
Joti Dina Kartikasari ◽  
Alfian Muttoqim Muttoqim ◽  
Umi Farida Farida ◽  
Amanda Oktaviani Amanda

The amount of paper waste, especially paper waste of yarn rolls in the socks manufactured factory and the convection industry that has not been used to get high economic value is an opportunity to open a new business, especially in the electronic and art craft product. SEPIK PANIK (Speaker of Music and Unique Display of Waste Paper Rolls) is an innovation from processing paper waste to be a unique speaker. The purposes of this program are: 1) Utilizing paper waste to get high selling value. 2) Creating handmade products from paper waste into speakers as well as unique creative display. 3) To accommodate the desire of college students who have entrepreneurial spirit and artistic creations to open new business opportunities. The method of make this SEPIK PANIK product includes 1) Making paper tube of speaker and 2) Making a Unique Display. The Sales of this product have been carried out during May to August 2019, products that have been sold are 34 units, obtained a profit of Rp. 1.170,000. Sales and promotion methods are carried out both online through social media and offline, namely direct selling and consignment. Based on these results, this business is very profitable and can benefit the surrounding environment.


Author(s):  
Aghnaita Aghnaita ◽  
Ajeng Almira Salsabila ◽  
Camelia Hanik ◽  
Maulida Syafitri ◽  
Norhayani Norhayani ◽  
...  

This study aims to determine the emotional social development of early childhood in Integrated Early Childhood Education Tarbiyatul Athfal UIN Antasari Banjarmasin as well as the form of learning activities undertaken as an effort to stimulate the emotional social development. The research method used is qualitative research on 6 children and learning activities that can stimulate children's emotional emotional development as primary data. Based on research conducted, the results obtained that the child's emotional social development tends to be unstable. Children often prefer to play alone. Nevertheless, children also begin to show interest in hanging out in the surrounding environment and doing play activities together. In addition, there are several factors influence, such as: social emotional experiences of children, gender differences, differences in family and cultural backgrounds, and parenting. While the form of learning activities that are pursued in the form of stimulation of children's emotional social development include: routine activities of reading Asmaul Husna and short surahs, filling in journals, playing indoor, and conducting learning activities. The activity was carried out through exemplary methods, sharing learning, and collaborative games.


2019 ◽  
Vol 8 (2) ◽  
Author(s):  
Didin Khaerudin ◽  
Suherli Kusmana ◽  
Iyay Robia Khaerudin

Research conducted to develop drama text teaching materials based on the experience of the author of the drama script aims to make it easier for students to understand drama text material. In addition, based on the author's experience students are expected to emulate the author's creative process in writing a paper. The research method used in this research is the research and development method. Based on the results of the interview it can be concluded that the ability to write drama is determined based on mastery of the elements of drama and the ability to develop stories based on the author's experience. The process of writing drama is done in several steps: (1) searching for ideas based on personal experience, other people, or the surrounding environment; (2) processing ideas to find plots (characters), characters or characters that vary with their inner conflicts, settings and dialogues, interesting conflicts, and messages to be conveyed; (3) starts the process of writing drama with stages and elements of drama; (4) revision of drama products. Teaching material developed is presented from basic competencies of knowledge and basic competencies of learning skills. Based on experiments on developed teaching materials it is known that the average value of the ability to write plays gets a score exceeding the minimum criteria, so that the teaching materials used are effective. Based on observations it is known that teaching materials can help students in learning and student activities become more independent, and active.


2020 ◽  
Vol 64 (4) ◽  
pp. 40407-1-40407-13 ◽  
Author(s):  
Ran Pang ◽  
He Huang ◽  
Tri Dev Acharya

Abstract Yongding River is one of the five major river systems in Beijing. It is located to the west of Beijing. It has influenced culture along its basin. The river supports both rural and urban areas. Furthermore, it influences economic development, water conservation, and the natural environment. However, during the past few decades, due to the combined effect of increasing population and economic activities, a series of changes have led to problems such as the reduction in water volume and the exposure of the riverbed. In this study, remote sensing images were used to derive land cover maps and compare spatiotemporal changes during the past 40 years. As a result, the following data were found: forest changed least; cropland area increased to a large extent; bareland area was reduced by a maximum of 63%; surface water area in the study area was lower from 1989 to 1999 because of the excessive use of water in human activities, but it increased by 92% from 2010 to 2018 as awareness about protecting the environment arose; there was a small increase in the built-up area, but this was more planned. These results reveal that water conservancy construction, agroforestry activities, and increasing urbanization have a great impact on the surrounding environment of the Yongding River (Beijing section). This study discusses in detail how the current situation can be attributed to of human activities, policies, economic development, and ecological conservation Furthermore, it suggests improvement by strengthening the governance of the riverbed and the riverside. These results and discussion can be a reference and provide decision support for the management of southwest Beijing or similar river basins in peri-urban areas.


2018 ◽  
Author(s):  
Kyle Hall ◽  
Zhengcai Zhang ◽  
Christian Burnham ◽  
Guang-Jun Guo ◽  
Sheelagh Carpendale ◽  
...  

<p>The broad scientific and technological importance of crystallization has led to significant research probing and rationalizing crystallization processes, particularly how nascent</p> <p>crystal phases appear. Previous work has generally neglected the possibility of the molecular-level dynamics of individual nuclei coupling to local structures (e.g., that of the nucleus and its</p> <p>surrounding environment). However, recent experimental work has conjectured that this can occur. Therefore, to address a deficiency in scientific understanding of crystallization, we have</p> <p>probed the nucleation of prototypical single and multi-component crystals (specifically, ice and mixed gas hydrates). Here, we establish that local structures can bias the evolution of nascent</p> <p>crystal phases on a nanosecond timescale by, for example, promoting the appearance or disappearance of specific crystal motifs, and thus reveal a new facet of crystallization behaviour.</p> <p>Analysis of the crystallization literature confirms that structural biases are likely present during crystallization processes beyond ice and gas hydrate formation. Moreover, we demonstrate that</p> <p>structurally-biased dynamics are a lens for understanding existing computational and experimental results while pointing to future opportunities.</p>


2018 ◽  
Author(s):  
Kyle Hall ◽  
Zhengcai Zhang ◽  
Christian Burnham ◽  
Guang-Jun Guo ◽  
Sheelagh Carpendale ◽  
...  

<p>The broad scientific and technological importance of crystallization has led to significant research probing and rationalizing crystallization processes, particularly how nascent</p> <p>crystal phases appear. Previous work has generally neglected the possibility of the molecular-level dynamics of individual nuclei coupling to local structures (e.g., that of the nucleus and its</p> <p>surrounding environment). However, recent experimental work has conjectured that this can occur. Therefore, to address a deficiency in scientific understanding of crystallization, we have</p> <p>probed the nucleation of prototypical single and multi-component crystals (specifically, ice and mixed gas hydrates). Here, we establish that local structures can bias the evolution of nascent</p> <p>crystal phases on a nanosecond timescale by, for example, promoting the appearance or disappearance of specific crystal motifs, and thus reveal a new facet of crystallization behaviour.</p> <p>Analysis of the crystallization literature confirms that structural biases are likely present during crystallization processes beyond ice and gas hydrate formation. Moreover, we demonstrate that</p> <p>structurally-biased dynamics are a lens for understanding existing computational and experimental results while pointing to future opportunities.</p>


2020 ◽  
Vol 33 (1) ◽  
Author(s):  
Qian Hui ◽  
Yan Li ◽  
Ye Tao ◽  
Hongwei Liu

AbstractA design problem with deficient information is generally described as wicked or ill-defined. The information insufficiency leaves designers with loose settings, free environments, and a lack of strict boundaries, which provides them with more opportunities to facilitate innovation. Therefore, to capture the opportunity behind the uncertainty of a design problem, this study models an innovative design as a composite solving process, where the problem is clarified and resolved from fuzziness to satisfying solutions by interplay among design problems, knowledge, and solutions. Additionally, a triple-helix structured model for the innovative product design process is proposed based on the co-evolution of the problem, solution, and knowledge spaces, to provide designers with a distinct design strategy and method for innovative design. The three spaces interact and co-evolve through iterative mappings, including problem structuring, knowledge expansion, and solution generation. The mappings carry the information processing and decision-making activities of the design, and create the path to satisfying solutions. Finally, a case study of a reactor coolant flow distribution device is presented to demonstrate the practicability of this model and the method for innovative product design.


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