Fabrication, characterization and in vitro digestion of food-grade β-carotene high loaded microcapsules: A wet-milling and spray drying coupling approach

LWT ◽  
2021 ◽  
pp. 112176
Author(s):  
Liang Zhang ◽  
Wenyan Liao ◽  
Yang Wei ◽  
Zhen Tong ◽  
Yuan Wang ◽  
...  
Keyword(s):  
Spray Drying ◽  
In Vitro Digestion ◽  
Wet Milling ◽  
Food Grade ◽  
Coupling Approach ◽  
Β Carotene

scholarly journals A Comparison of Microfluidic-Jet Spray Drying, Two-Fluid Nozzle Spray Drying, and Freeze-Drying for Co-Encapsulating β-Carotene, Lutein, Zeaxanthin, and Fish Oil

Foods ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1522
Author(s):  
Yongchao Zhu ◽  
Yaoyao Peng ◽  
Jingyuan Wen ◽  
Siew Young Quek
Keyword(s):  
Particle Size ◽  
Fish Oil ◽  
Spray Drying ◽  
Freeze Drying ◽  
Morphological Characteristics ◽  
In Vitro Digestion ◽  
Drying Methods ◽  
Two Fluid ◽  
Β Carotene

Various microencapsulation techniques can result in significant differences in the properties of dried microcapsules. Microencapsulation is an effective approach to improve fish oil properties, including oxidisability and unpleasant flavour. In this study, β-carotene, lutein, zeaxanthin, and fish oil were co-encapsulated by microfluidic-jet spray drying (MFJSD), two-fluid nozzle spray drying (SD), and freeze-drying (FD), respectively. The aim of the current study is to understand the effect of different drying techniques on microcapsule properties. Whey protein isolate (WPI) and octenylsuccinic anhydride (OSA) modified starch were used as wall matrices in this study for encapsulating carotenoids and fish oil due to their strong emulsifying properties. Results showed the MFJSD microcapsules presented uniform particle size and regular morphological characteristics, while the SD and FD microcapsules presented a large distribution of particle size and irregular morphological characteristics. Compared to the SD and FD microcapsules, the MFJSD microcapsules possessed higher microencapsulation efficiency (94.0–95.1%), higher tapped density (0.373–0.652 g/cm3), and higher flowability (the Carr index of 16.0–30.0%). After a 4-week storage, the SD microcapsules showed the lower retention of carotenoids, as well as ω-3 LC-PUFAs than the FD and MFJSD microcapsules. After in vitro digestion trial, the differences in the digestion behaviours of the microcapsules mainly resulted from the different wall materials, but independent of drying methods. This study has provided an alternative way of delivering visual-beneficial compounds via a novel drying method, which is fundamentally essential in both areas of microencapsulation application and functional food development.

Impact of trehalose on physicochemical stability of β-carotene high loaded microcapsules fabricated by wet-milling coupled with spray drying

2021 ◽  
pp. 106977
Author(s):  
Liang Zhang ◽  
Yang Wei ◽  
Wenyan Liao ◽  
Zhen Tong ◽  
Yuan Wang ◽  
...  
Keyword(s):  
Spray Drying ◽  
Wet Milling ◽  
Physicochemical Stability ◽  
Β Carotene

Evaluation of Cellular Absorption and Metabolism of β-Carotene Loaded in Nanocarriers after In Vitro Digestion

2021 ◽  
Author(s):  
Ling Chen ◽  
Wallace Yokoyama ◽  
Christina Tam ◽  
Yuqing Tan ◽  
Pricilla Alves ◽  
...  
Keyword(s):  
In Vitro Digestion ◽  
Β Carotene

Bioavailability of β-carotene isomers from raw and cooked carrots using an in vitro digestion model coupled with a human intestinal Caco-2 cell model

2010 ◽  
Vol 43 (5) ◽  
pp. 1449-1454 ◽  
Author(s):  
S. Aisling Aherne ◽  
Trevor Daly ◽  
Marvin A. Jiwan ◽  
Laurie O’Sullivan ◽  
Nora M. O’Brien
Keyword(s):  
Cell Model ◽  
In Vitro Digestion ◽  
Β Carotene

scholarly journals Interactions of β-carotene with WPI/Tween 80 mixture and oil phase: Effect on the behavior of O/W emulsions during in vitro digestion

2021 ◽  
Vol 341 ◽  
pp. 128155
Author(s):  
Andresa Gomes ◽  
Ana Letícia Rodrigues Costa ◽  
Dayane Dias Cardoso ◽  
Grazielle Náthia-Neves ◽  
M. Angela A. Meireles ◽  
...  
Keyword(s):  
Tween 80 ◽  
In Vitro Digestion ◽  
Phase Effect ◽  
Β Carotene

scholarly journals Sea Buckthorn Oil as a Valuable Source of Bioaccessible Xanthophylls

Nutrients ◽  
2019 ◽  
Vol 12 (1) ◽  
pp. 76 ◽  
Author(s):  
Cristina Tudor ◽  
Torsten Bohn ◽  
Mohammed Iddir ◽  
Francisc Vasile Dulf ◽  
Monica Focşan ◽  
...  
Keyword(s):  
In Vitro Digestion ◽  
Sea Buckthorn ◽  
Cholesterol Esterase ◽  
Water Emulsion ◽  
Oil In Water ◽  
Sea Buckthorn Oil ◽  
Oil In Water Emulsion ◽  
Zeaxanthin Dipalmitate ◽  
Β Carotene

Sea buckthorn oil, derived from the fruits of the shrub, also termed seaberry or sandthorn, is without doubt a strikingly rich source of carotenoids, in particular zeaxanthin and β-carotene. In the present study, sea buckthorn oil and an oil-in-water emulsion were subjected to a simulated gastro-intestinal in vitro digestion, with the main focus on xanthophyll bioaccessibility. Zeaxanthin mono- and di-esters were the predominant carotenoids in sea buckthorn oil, with zeaxanthin dipalmitate as the major compound (38.0%). A typical fatty acid profile was found, with palmitic (49.4%), palmitoleic (28.0%), and oleic (11.7%) acids as the dominant fatty acids. Taking into account the high amount of carotenoid esters present in sea buckthorn oil, the use of cholesterol esterase was included in the in vitro digestion protocol. Total carotenoid bioaccessibility was higher for the oil-in-water emulsion (22.5%) compared to sea buckthorn oil (18.0%) and even higher upon the addition of cholesterol esterase (28.0% and 21.2%, respectively). In the case of sea buckthorn oil, of all the free carotenoids, zeaxanthin had the highest bioaccessibility (61.5%), followed by lutein (48.9%), making sea buckthorn oil a potential attractive source of bioaccessible xanthophylls.

scholarly journals Bio-Based Nanoparticles as a Carrier of β-Carotene: Production, Characterisation and In Vitro Gastrointestinal Digestion

Molecules ◽  
2020 ◽  
Vol 25 (19) ◽  
pp. 4497
Author(s):  
Beatriz S. Afonso ◽  
Ana G. Azevedo ◽  
Catarina Gonçalves ◽  
Isabel R. Amado ◽  
Eugénio C. Ferreira ◽  
...  
Keyword(s):  
Encapsulation Efficiency ◽  
In Vitro Digestion ◽  
X Ray Diffraction ◽  
X Ray ◽  
Transmission Electron ◽  
Mean Size ◽  
Average Size ◽  
Size Controlled ◽  
Β Carotene

β-carotene loaded bio-based nanoparticles (NPs) were produced by the solvent-displacement method using two polymers: zein and ethylcellulose. The production of NPs was optimised through an experimental design and characterised in terms of average size and polydispersity index. The processing conditions that allowed to obtain NPs (<100 nm) were used for β-carotene encapsulation. Then β-carotene loaded NPs were characterised in terms of zeta potential and encapsulation efficiency. Transmission electron microscopy, Fourier transform infrared spectroscopy and X-ray diffraction analysis were performed for further morphological and chemical characterisation. In the end, a static in vitro digestion following the INFOGEST protocol was performed and the bioaccessibility of β-carotene encapsulated in both NPs was determined. Results show that the best conditions for a size-controlled production with a narrow size distribution are lower polymer concentrations and higher antisolvent concentrations. The encapsulation of β-carotene in ethylcellulose NPs resulted in nanoparticles with a mean average size of 60 ± 9 nm and encapsulation efficiency of 74 ± 2%. β-carotene loaded zein-based NPs resulted in a mean size of 83 ± 8 nm and encapsulation efficiency of 93 ± 4%. Results obtained from the in vitro digestion showed that β-carotene bioaccessibility when encapsulated in zein NPs is 37 ± 1%, which is higher than the value of 8.3 ± 0.1% obtained for the ethylcellulose NPs.

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