Association of hormonal exposure with walking function among French women: data from the CONSTANCES Study

Maturitas ◽  
2021 ◽  
Vol 152 ◽  
pp. 77
Author(s):  
Maryline Laine-Le Noan ◽  
Fanny Artaud ◽  
Anna Ozguler ◽  
Mireille Pellicer ◽  
Alexis Elbaz ◽  
...  
Keyword(s):  
1977 ◽  
Vol 3 (1-2) ◽  
pp. 97-121 ◽  
Author(s):  
Roger A. Gorski ◽  
Richard E. Harlan ◽  
Larry W. Christensen

2013 ◽  
Vol 20 (5) ◽  
pp. 635-646 ◽  
Author(s):  
Dania Daye ◽  
Brad Keller ◽  
Emily F. Conant ◽  
Jinbo Chen ◽  
Mitchell D. Schnall ◽  
...  

2015 ◽  
Author(s):  
Jaqueline C. Rinaldi ◽  
Caroline N. Barquilha ◽  
Sergio AA Santos ◽  
Ana C. Camargo ◽  
Ketlin T. Colombelli ◽  
...  

2013 ◽  
Vol 76 (1) ◽  
pp. 117-124 ◽  
Author(s):  
Sławomir Kozieł ◽  
Raja Chakraborty ◽  
Aneta Sitek

Abstract This aims of this research are to determine if the 2D:4D digit ratio is related to subjective pain experience during tattooing and to examine gender differences therein. The study involved 43 male and 28 female Polish adults recruited from two tattoo salons in Wroclaw and Leszno in Western Poland. These subjects were asked if they felt pain during their tattooing and answers were recorded as ‘Yes’ or ‘No’. The ventral surface lengths of the second and fourth digits of each hand were measured, and analysis of variance was performed to assess significant differences in the 2D:4D ratios of right and left hands and twohand averages between genders and the Yes/ No groups reporting pain experience. Results revealed that although the digit ratios for females had systematically higher values than those in males, differences were not statistically significant. Both sex and subjective pain feeling were significantly associated with 2D:4D ratio in both hands and their average values, while sex and pain experience were independently associated with digit ratio. Subjects who felt pain during tattooing had a significantly lower digit ratio. In conclusion, the study did not support the hypothesis that the lower masculine 2D:4D ratio is associated with a higher pain threshold. Prenatal sex hormonal exposure generating the gender dimorphic 2D:4D index may not predispose the actual feeling of all kinds of pain; in this instance, not in pain associated with tattooing.


1995 ◽  
Vol 29 (2) ◽  
pp. 278-283 ◽  
Author(s):  
Nathaniel McConaghy ◽  
Ruth Zamir

Masculinity and femininity have been studied by self-ratings in independent areas of research: one investigating personality traits considered masculine (M) or feminine (F); the other, behaviours statistically more common in one than in the other sex (sex-linked behaviours). The two approaches were compared for the first time in the present study of 66 male and 51 female medical students. Consistent with previous findings using the second approach, male but not female subjects' opposite sex-linked “sissy” and “tom-boyish” behaviours correlated significantly with their reported ratio of homosexual to heterosexual feelings (Ho/Het). Ho/Het did not correlate with either sex's M and F scores, but high M scores in women correlated strongly with several “tomboyish” behaviours. As “tomboyish” behaviours are shown more strongly by women exposed prenatally to increased levels of opposite sex hormones compared to controls, the findings have implications for the biological theory attributing Ho/Het to such prenatal hormonal exposure.


eLife ◽  
2019 ◽  
Vol 8 ◽  
Author(s):  
Constantin Hays ◽  
Gérald Touak ◽  
Abdelouhab Bouaboud ◽  
Agnès Fouet ◽  
Julie Guignot ◽  
...  

Group B Streptococcus (GBS) is the leading cause of invasive bacterial neonatal infections. Late-onset diseases (LOD) occur between 7 and 89 days of life and are largely due to the CC17 GBS hypervirulent clone. We studied the impact of estradiol (E2) and progesterone (P4), which impregnate the fetus during pregnancy, on GBS neonatal infection in cellular and mouse models of hormonal exposure corresponding to concentrations found at birth (E2-P4 C0) and over 7 days old (E2-P4 C7). Using representative GBS isolates, we show that E2-P4 C7 concentrations specifically favor CC17 GBS meningitis following mice oral infection. CC17 GBS crosses the intestinal barrier through M cells. This process mediated by the CC17-specific surface protein Srr2 is enhanced by E2-P4 C7 concentrations which promote M cell differentiation and CC17 GBS invasiveness. Our findings provide an explanation for CC17 GBS responsibility in LOD in link with neonatal gastrointestinal tract maturation and hormonal imprint.


PEDIATRICS ◽  
1973 ◽  
Vol 51 (2) ◽  
pp. 297-299
Author(s):  
Sumner J. Yaffe ◽  
Charles W. Bierman ◽  
Howard M. Cann ◽  
Arnold P. Gold ◽  
Frederic M. Kenny ◽  
...  

One of the most important concepts in pediatric pharmacology is that exposure to drugs or chemicals may have latent, unforeseen effects on the child later in life. Some of the most dramatic occurrences, other than teratogenesis, are those in which hormonal exposure during the fetal or newborn period alters adult sexual development. However, none of these episodes is more impressive and ominous than that reported by Herbst et al.1 Herbst, an obstetrician at the Massachusetts General Hospital, was intrigued by the presentation of seven patients with adenocarcinoma of the vagina, an extremely rare tumor not previously seen at the hospital. The patients ranged in age from 14 to 22 years and sought medical advice because of vaginal bleeding. Several had benign adenosis, suggesting that the malignant change seen in all was based on a fundamental alteration in the biology of the vaginal epithelium. Six of the patients were treated with radical surgery, and one was treated with wide, local excision. One of the patients died after surgery. In what could serve as a model of a scientifically conducted, epidemiologic study, each of the seven patients, plus an additional patient from another hospital, was matched with four controls born in the same hospital within four days. Thus, the "control" group was chosen in a manner to eliminate many biases of artificially contrived control populations. A wide variety of possible influences in both mothers and offspring were considered, e.g., maternal age, smoking habits, exposure to X-rays, breast-feeding, birth weight, age at menarche, medications during pregnancy, and so forth.


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