MR imaging of Oral Cavity and Oropharyngeal Cancer

2022 ◽  
Vol 30 (1) ◽  
pp. 35-51
Ahmed Abdel Khalek Abdel Razek ◽  
Manar Mansour ◽  
Elsharawy Kamal ◽  
Suresh K. Mukherji
Antonello Vidiri ◽  
Davide Curione ◽  
Francesca Piludu ◽  
Antonino Guerrisi ◽  
Barbara Pichi ◽  

Cancer ◽  
2021 ◽  
Vol 127 (10) ◽  
pp. 1638-1647
Yuh‐Seog Jung ◽  
Jungirl Seok ◽  
Seri Hong ◽  
Chang Hwan Ryu ◽  
Junsun Ryu ◽  

2019 ◽  
Vol 72 (6) ◽  
pp. 464-477 ◽  
Mathieu Balaguer ◽  
Jérôme Farinas ◽  
Pascale Fichaux-Bourin ◽  
Michèle Puech ◽  
Julien Pinquier ◽  

<b><i>Context:</i></b> Nowadays, clinical tools are available to evaluate the functional impact of speech disorders in neurological conditions, but few are validated in oncology. Because of their location, cancers of the upper aerodigestive tract directly impact patients’ communication skills. Two questionnaires exist in French, the Speech Handicap Index (SHI) and the Phonation Handicap Index (PHI), but none are specifically validated for the head and neck cancer population. Our aim is to evaluate the validity of these 2 questionnaires in a population of patients treated for oral cavity or oropharyngeal cancer. <b><i>Material and Method:</i></b> Eighty-seven patients treated for cancer of the oral cavity or oropharynx, and 21 controls filled in the questionnaires during a consultation or 1-day hospitalization. Validation was studied by the analysis of convergent and discriminant validity, clinical validity, criterion validity, and internal consistency. <b><i>Results:</i></b> The 2 questionnaires present a coherent structure in 2 distinct dimensions for the SHI, and in 3 dimensions for the PHI. Both tools discriminate patients and healthy subjects (<i>p</i> value &#x3c;0.001, Mann-Whitney test). The comparison of the SHI and PHI scores with the “social role functioning” dimension of the Medical Outcome Study Short Form 36 chosen as a reference shows similar performances for the 2 questionnaires (ρ &#x3e; 0.42). Lastly, the internal consistency is good (Cronbach’s α &#x3e; 0.71). <b><i>Conclusion:</i></b> In patients treated for oral cavity or oropharyngeal cancer, the SHI and PHI are 2 valid and reliable tools for the self-assessment of speech disability. A limitation can be found about criterion validity, because a true gold standard does not exist at the moment. However, the reduced number of questions of the PHI, which implies a shorter completion, leads to prefer this tool over the SHI.

2018 ◽  
Vol 127 (12) ◽  
pp. 895-902 ◽  
Man Hin Chan ◽  
Feng Wang ◽  
Wai kong Mang ◽  
Lap Ah Tse

Objectives: Worldwide studies have shown an increasing trend of oropharyngeal squamous cell carcinoma (OPSCC) but a decreasing trend of oral cavity cancers over the past 2 decades, particularly in developed countries with successful tobacco control. This trend has been attributed to the increase in the incidence of human papillomavirus (HPV)–associated OPSCC. The aim of this study was to examine sex differences in incidence trends of oropharyngeal and oral cavity cancers in Hong Kong from 1983 to 2014. Methods: Using data from the Hong Kong Cancer Registry from 1983 to 2014, age-standardized incidence rates for potentially HPV-associated sites (oropharyngeal) and non-HPV-associated sites (oral cavity) were calculated, stratified by sex and age groups. Joinpoint regression and an age-period-cohort model were used to assess incidence trends. Results: A total of 1,972 cases of oropharyngeal cancer and 7,389 cases of oral cavity cancer were diagnosed from 1983 to 2014. The male/female ratios were 4.16:1 for oropharyngeal cancers and 1.63:1 for oral cavity cancers. A significant increasing trend was observed in oropharyngeal cancers from 1994 to 2014 (average annual percentage change = 2.66, P < .05). In contrast, a significant decreasing trend was observed in oral cavity cancers from 1983 to 1994 (average annual percentage change = −5.36, P < .05). The trends were more significant in men and in patients aged 45 to 69 years. A positive birth cohort effect was observed for oropharyngeal cancer in men. Conclusions: The rising trend of oropharyngeal cancer and decreasing trend of oral cavity cancer in Hong Kong from 1983 to 2014 are consistent with worldwide trends. Increase in high-risk sexual behaviors and oral HPV infection may influence the difference in trends.

2009 ◽  
Vol 119 (S1) ◽  
pp. S60-S60
Jason P. Champagne ◽  
Paul M. Weinberger ◽  
Lana L. Jackson

2016 ◽  
Vol 27 (3) ◽  
pp. 261-266 ◽  
Renata Costa de Moraes ◽  
Fernando Luiz Dias ◽  
Carlos Marcelo da Silva Figueredo ◽  
Ricardo Guimarães Fischer

Abstract The aim of this case control study was to assess the association between the extent and severity of chronic periodontitis and oral cavity and/or oropharyngeal cancer. The case group comprised 35 patients (mean age 56.1±8.4), diagnosed for oral and/or oropharyngeal cancer. The control group comprised 40 individuals (mean age 55.4±9.4) without diagnostic of cancer. All individuals were subjected to a periodontal examination, including bleeding on probing, plaque index, gingival index, probing pocket depth (PPD), clinical attachment loss (CAL), and decayed, extracted and filled teeth index (DMFT). The case group had significantly more sites with plaque. GI and BOP had similar values in both groups. The median PPD and CAL values were significantly higher for the case group. Chronic generalized periodontitis was predominant in 80% of patients with oral and/or oropharyngeal cancer. Eighty nine percent of the patients in the case group presented severe chronic periodontitis. There was no significant difference between groups for median values of DMFT. The extent and severity of chronic periodontitis remained as risk indicators for oral cavity and/or oropharyngeal cancer even after the adjustments for traditional confound factors, i.e. smoking and alcohol consumption.

2015 ◽  
Vol 39 (4) ◽  
pp. 497-504 ◽  
Darien J. Weatherspoon ◽  
Amit Chattopadhyay ◽  
Shahdokht Boroumand ◽  
Isabel Garcia

2017 ◽  
Vol 17 (1) ◽  
Hiromitsu Hatakeyama ◽  
Noriyuki Fujima ◽  
Kazuhiko Tsuchiya ◽  
Kenji Mizoguchi ◽  
Takatsugu Mizumachi ◽  

2019 ◽  
Gang Zheng ◽  
Lei Feng ◽  
Carol M Lewis

Abstract Background: Oral cavity and oropharyngeal cancer impose significant threat to airway management. Head and neck radiotherapy (HNRT) may further increase the difficulty of tracheal intubation. We hypothesized that a history of HNRT would be associated with a high rate of difficult tracheal intubation. Methods: Adult patients with a history of HNRT were identified. Non-HNRT controls were case-matched by age, sex and body mass index. The tracheal intubation status between the two patient groups (treated vs. untreated with HNRT) was compared. The t test was used to evaluate differences in continuous variables between the 2 groups. Fisher’s exact test or a chi-square test was used to test for associations between radiation status and patient characteristics that may be associated with difficult tracheal intubation. Odds ratio and its confidence interval were used to assess the effect of radiation status on intubation status. Results: The final cohort of 472 matched patients in age, sex and body mass index consisted of 236 patients who had HNRT before surgery and 236 who had upfront surgery without HNRT. The percentage of patients who had restricted neck range of motion in the HNRT group was significantly higher than in the control group (22.3% vs. 11.0%; P = 0.001). The proportion of patients with trismus (P = 0.11) or difficult tracheal intubation (p = 0.73) did not differ significantly between the 2 groups. 12.7% patients in the study had difficult tracheal intubation. Patients who had mallampati scores of 3 or 4 had significantly higher rate of difficult tracheal intubation than did patients with mallampati scores of 1 or 2 (17.8% vs. 8.7%; p = 0.004). Multivariate logistic regression model showed no difference between HNRT and intubation status after adjusting neck range of motion and mallampati score (OR=0.91, 95% CI: 0.510 to1.612) Conclusions: Previous treatment with HNRT was not associated with additional risk of difficult tracheal intubation. Mallampati score may be a sensitive measurement for difficult tracheal intubation in this patient population.

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