Sex Differences in Time Trends on Incidence Rates of Oropharyngeal and Oral Cavity Cancers in Hong Kong

2018 ◽  
Vol 127 (12) ◽  
pp. 895-902 ◽  
Author(s):  
Man Hin Chan ◽  
Feng Wang ◽  
Wai kong Mang ◽  
Lap Ah Tse
Keyword(s):  
Sex Differences ◽  
Hong Kong ◽  
Oral Cavity ◽  
Oropharyngeal Cancer ◽  
Oral Cavity Cancer ◽  
Incidence Rates ◽  
Annual Percentage Change ◽  
Incidence Trends ◽  
Increasing Trend ◽  
Oral Cavity Cancers

Objectives: Worldwide studies have shown an increasing trend of oropharyngeal squamous cell carcinoma (OPSCC) but a decreasing trend of oral cavity cancers over the past 2 decades, particularly in developed countries with successful tobacco control. This trend has been attributed to the increase in the incidence of human papillomavirus (HPV)–associated OPSCC. The aim of this study was to examine sex differences in incidence trends of oropharyngeal and oral cavity cancers in Hong Kong from 1983 to 2014. Methods: Using data from the Hong Kong Cancer Registry from 1983 to 2014, age-standardized incidence rates for potentially HPV-associated sites (oropharyngeal) and non-HPV-associated sites (oral cavity) were calculated, stratified by sex and age groups. Joinpoint regression and an age-period-cohort model were used to assess incidence trends. Results: A total of 1,972 cases of oropharyngeal cancer and 7,389 cases of oral cavity cancer were diagnosed from 1983 to 2014. The male/female ratios were 4.16:1 for oropharyngeal cancers and 1.63:1 for oral cavity cancers. A significant increasing trend was observed in oropharyngeal cancers from 1994 to 2014 (average annual percentage change = 2.66, P < .05). In contrast, a significant decreasing trend was observed in oral cavity cancers from 1983 to 1994 (average annual percentage change = −5.36, P < .05). The trends were more significant in men and in patients aged 45 to 69 years. A positive birth cohort effect was observed for oropharyngeal cancer in men. Conclusions: The rising trend of oropharyngeal cancer and decreasing trend of oral cavity cancer in Hong Kong from 1983 to 2014 are consistent with worldwide trends. Increase in high-risk sexual behaviors and oral HPV infection may influence the difference in trends.

scholarly journals Trends in the incidence rates of tonsil and base of tongue cancer in England, 1985–2006

2010 ◽  
Vol 92 (8) ◽  
pp. 655-659 ◽  
Author(s):  
VM Reddy ◽  
D Cundall-Curry ◽  
MWM Bridger
Keyword(s):  
Linear Regression ◽  
Oral Cavity ◽  
Oropharyngeal Cancer ◽  
Oral Cavity Cancer ◽  
Tongue Cancer ◽  
Incidence Rates ◽  
Cancer Information ◽  
Men And Women ◽  
Base Of Tongue ◽  
Adjusted Incidence

INTRODUCTION The aim of this study was to investigate whether incidence rates of tonsil and base of tongue cancer in England are increasing using data from the UK cancer registry. SUBJECTS AND METHODS Cancer registrations for oral cavity and oropharynx cancer from 1985–2006 in England were obtained from the National Cancer Information Service. Population estimates were obtained from the Office for National Statistics. Age-adjusted incidence rates and age-specific incidence rates were calculated. The sexes were considered separately as incidence rates are known to differ significantly between men and women. Linear regression was performed to establish whether there was a relationship between incidence rates and time. RESULTS There has been an increase in all oral cavity and oropharyngeal cancer in the study period. Linear regression analysis suggests that approximately 90% of the variance in age-adjusted incidence rates for men and women for tonsil, base of tongue and other oral cavity cancer is explained by the passage of time. For other oropharyngeal cancer, the variance is 62% and 46% in men and women, respectively. The estimated annual percentage change from 1985 to 2006 in age-adjusted incidence rates for tonsil and base of tongue cancer is 5.7% and 6.7% for men, and 4.3% and 6.5% for women, respectively. CONCLUSIONS This study confirms a wide-spread clinical impression that there has been an increase in age-adjusted incidence rates, between 1985 and 2006, in all oral cavity cancer in England. The age range 40–69 years has seen the biggest increases in age-specific incidence rates for tonsil and base of tongue cancer. This reflects the findings of similar studies in other countries.

The emergence of oral cavity cancer and the stabilization of oropharyngeal cancer: Recent contrasting epidemics in the South Korean population

Cancer ◽  
2021 ◽  
Vol 127 (10) ◽  
pp. 1638-1647
Author(s):  
Yuh‐Seog Jung ◽  
Jungirl Seok ◽  
Seri Hong ◽  
Chang Hwan Ryu ◽  
Junsun Ryu ◽  
...  
Keyword(s):  
Oral Cavity ◽  
Oropharyngeal Cancer ◽  
Oral Cavity Cancer ◽  
Korean Population ◽  
The South ◽  
South Korean

scholarly journals Increasing incidence of anaphylaxis in Hong Kong from 2009 to 2019—discrepancies of anaphylaxis care between adult and paediatric patients

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Philip Hei Li ◽  
Agnes S. Y. Leung ◽  
Rebecca M. Y. Li ◽  
Ting-fan Leung ◽  
Chak-sing Lau ◽  
...  
Keyword(s):  
Hong Kong ◽  
Incidence Rate ◽  
Developed Countries ◽  
Paediatric Population ◽  
Incidence Rates ◽  
Published Data ◽  
The Past ◽  
Paediatric Patients ◽  
Increasing Trend ◽  
Prescription Rates

Abstract Background Anaphylaxis has been increasing in developed countries but there is very little published data on the burden of anaphylaxis and the pattern of adrenaline autoinjector (AAI) prescription from Asia. We aim to determine the incidence rates of anaphylaxis and prescription rates of AAI over the past decade in Hong Kong. Methods Using a centralized electronic database of Hong Kong’s sole public-funded healthcare provider, we obtained and analysed all patients between 2009 and 2019 with physician-reported diagnosis of anaphylaxis. Incidence rates were calculated using population statistics as the denominator. Patients’ prescriptions on discharge were collected to determine the AAI prescription rates. Results The overall 10-year estimated incidence rate of anaphylaxis was 3.57 per 100,000 person-years. An increasing trend over time across both paediatric and adult populations from 2009 to 2014 was found, which remained stable until 2019. This was more marked among the paediatric population (paediatric vs adult incidence rate ratio in 2019: 3.51 [95% CI 1.12–2.66] vs 1.82 [95% CI 1.05–1.60]). There was an overall increasing rate of AAI prescription for patients admitted for anaphylaxis, but the overall AAI prescription rate was less than 15% and was significantly less likely to be prescribed for the adult compared to paediatric patients (36.5% vs. 89.4%, p < 0.001). Conclusions An increasing trend of anaphylaxis incidence rates over the past decade is evident in Asian populations, with a discrepantly low rate of AAI prescription, particularly in the adult patients.

Incidence Trends of Lip, Oral Cavity, and Pharyngeal Cancers: Global Burden of Disease 1990–2017

2019 ◽  
Vol 99 (2) ◽  
pp. 143-151 ◽  
Author(s):  
M. Du ◽  
R. Nair ◽  
L. Jamieson ◽  
Z. Liu ◽  
P. Bi
Keyword(s):  
Oral Cavity ◽  
Burden Of Disease ◽  
Age Groups ◽  
Global Burden Of Disease ◽  
Mortality Data ◽  
Global Burden ◽  
Middle Income ◽  
Incidence Trends ◽  
Oral Cavity Cancers ◽  
Incident Cases

The worldwide incidence trends of the lip, oral cavity, and pharyngeal cancers (LOCPs) need to be updated. This study aims to examine the temporal incidence trends of LOCPs from 1990 to 2017, using the latest Global Burden of Disease (GBD) study data to explore sex, age, and regional differences. GBD incidence data for LOCPs were driven by population cancer registries and were estimated from mortality data. Age-standardized incidence rates (ASIRs) were directly extracted from the 2017 GBD database to calculate the estimated annual percentage change (EAPC) over the study period. Incidence trends are mapped and compared separately by sex (females vs. males), age groups (15–49, 50–69, and 70+ y), regions (21 geographical and 5 sociodemographic regions), and countries. Among 678,900 incident cases of LOCPs notified in 2017, more than half were lip and oral cavity cancers. From 1990 to 2017, the estimated global incidence for nasopharyngeal cancers decreased dramatically (EAPC = −1.52; 95% confidence interval [CI], –1.70 to −1.34), while the incidence for lip and oral cavity cancers (EAPC = 0.26; 95% CI, 0.16–0.37) and other pharyngeal cancers (EAPC = 0.62; 95% CI, 0.54–0.71) increased. Higher ASIRs were observed among males than females across all age groups. However, females had larger EAPC variation when compared to males. Population groups aged 15 to 49 y presented the lowest ASIRs, with larger values of EAPC than those aged 50 to 69 and 70+ y. While high-income countries had higher ASIRs with little EAPC variation, ASIRs varied across low/middle-income regions with larger EAPC variations. South Asia and East Asia had the highest ASIRs and EAPC for lip and oral cavity cancers, respectively. In conclusion, the global incidence of LOCPs has increased among females, those aged 15 to 49 y, and people from low/middle-income countries over the study period, excepting nasopharyngeal cancers, which had a decreasing worldwide trend.

scholarly journals Oral cavity and oropharyngeal cancer incidence trends and disparities in the United States: 2000–2010

2015 ◽  
Vol 39 (4) ◽  
pp. 497-504 ◽  
Author(s):  
Darien J. Weatherspoon ◽  
Amit Chattopadhyay ◽  
Shahdokht Boroumand ◽  
Isabel Garcia
Keyword(s):  
United States ◽  
Oral Cavity ◽  
Cancer Incidence ◽  
Oropharyngeal Cancer ◽  
The United States ◽  
Incidence Trends

Conceptual Study of Anukta Vyadhi – Oral Cavity Cancer with special reference to Mukhagata Roga

2020 ◽  
Vol 8 (01) ◽  
Author(s):  
Sushrut Sardeshmukh
Keyword(s):  
Oral Cavity ◽  
Special Reference ◽  
Oral Cavity Cancer ◽  
Modern Medicine ◽  
Classical Literature ◽  
Conceptual Study ◽  
Oral Cavity Cancers

Cancer is known as one of the most dreaded diseases globally as well as in India. Cancer as a single disease is not mentioned in any of the Ayurveda classical literature, but diseases having similar conditions like Dushta Vrana, Dushta Granthi, Dushta Arbuda, Dushta Nadivrana etc. have been described in Ayurveda classical texts. Mukhagata Roga have been described in Sushruta Samhita, Charak Samhita, Ashtanga Hridaya, Yoga Ratnakar and Madhava Nidan. To understand the Nidan of oral cavity cancers according to Ayurveda, we have to understand the Hetu, Dosha Dushti and Samprapti causing the specific Mukhagata Roga. The different ‘Vyadhi Roopa’ or ‘Vyadhi Lakshana’ depends on the predominance of the Vikruta Dosha. In ‘Mukha Pradesh’ (Oral cavity) too, various diseases and symptoms are seen due to vitiated Doshas which resemble to Arbuda and can be correlated to oral cavity cancers. For the study of oral cavity cancers with an Ayurvedic perspective, available references from modern medicine like texts, articles, journals as well as Ayurveda literature viz. Bruhat Trayi, Madhav  Nidan, Yoga Ratnakar were collected and analyzed in a systematic manner.

Comparison of psychosocial factors over time among HPV+ oropharyngeal cancer and tobacco-related oral cavity cancer patients

2019 ◽  
Vol 40 (1) ◽  
pp. 40-45 ◽  
Author(s):  
Tyler A. Janz ◽  
Suhael R. Momin ◽  
Katherine R. Sterba ◽  
Masanari G. Kato ◽  
Kent E. Armeson ◽  
...  
Keyword(s):  
Oral Cavity ◽  
Cancer Patients ◽  
Psychosocial Factors ◽  
Oropharyngeal Cancer ◽  
Oral Cavity Cancer ◽  
Over Time

scholarly journals The incidence trends of liver cirrhosis caused by nonalcoholic steatohepatitis via the GBD study 2017

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Mimi Zhai ◽  
Zhide Liu ◽  
Jianhai Long ◽  
Qingxiang Zhou ◽  
Leping Yang ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Nonalcoholic Steatohepatitis ◽  
Incidence Rates ◽  
Asia Pacific ◽  
Distribution Characteristics ◽  
Chronic Liver Diseases ◽  
Growth Trend ◽  
Incidence Trends ◽  
Increasing Trend ◽  
Near Future

AbstractNonalcoholic steatohepatitis (NASH) has rapidly become the most common cause of chronic liver diseases. We aimed to explore the incidence and distribution characteristics of NASH by sex, region and sociodemographic index (SDI). We collected data, including sex and region, on NASH-related liver cirrhosis from the 2017 GBD study. The age-standardized incidence rates (ASRs) and estimated annual percentage changes (EAPCs) were used to estimate the incidence trend and distribution characteristics. Globally, the incidence of liver cirrhosis caused by NASH increased from 178,430 cases in 1990 to 367,780 cases in 2017, an increase of approximately 105.56%. The ASR of NASH increased by an average of 1.35% per year (95% CI 1.28–1.42). Meanwhile, large differences in the ASR and the EAPC were observed across regions. The middle-high SDI region had the highest increase among all five SDI regions, followed by middle SDI region. In addition, Eastern Europe, Andean Latin America and Central Asia showed a more significant growth trend of ASR. In contrast, the high SDI region demonstrated the slowest increasing trend of ASR, and the high-income Asia Pacific demonstrated a decreasing trend among the 21 regions. Liver cirrhosis has caused a huge and rising health burden in many countries and regions. In addition, with the growth of obesity, population and aging, NASH might replace viral hepatitis as the most important cause of liver cirrhosis in the near future. Therefore, appropriate interventions are needed in coming decades to realize early diagnosis and prevention of NASH-related liver cirrhosis.

scholarly journals Trends in Colorectal Cancer Incidence Rates in Saudi Arabia (2001–2016) Using Saudi National Registry: Early- Versus Late-Onset Disease

2021 ◽  
Vol 11 ◽  
Author(s):  
Mesnad Alyabsi ◽  
Mohammed Algarni ◽  
Kanan Alshammari
Keyword(s):  
Colorectal Cancer ◽  
Health Care Providers ◽  
Early Onset ◽  
Late Onset ◽  
Incidence Rates ◽  
National Registry ◽  
Percentage Change ◽  
Annual Percentage Change ◽  
Care Providers ◽  
Incidence Trends

Early-onset (&lt;50 years old) colorectal cancer (CRC) has been increasing worldwide and is associated with poor outcomes. Over 85% of the Saudi population are &lt;50 years old, which put them at heightened risk of early-onset CRC. No study assessed the trends in CRC incidence rates among the Saudis. The Joinpoint Regression software by the Surveillance, Epidemiology, and End Results (SEER) program was used to estimate the magnitude and direction of CRC incidence trends by age and gender. The annual percentage change (APC) and the average annual percentage change (AAPC) between 2001 and 2016 were computed. In a sensitivity analysis, we also assessed trends using various age groups. Between 2001 and 2016, the early-onset CRC incidence (per 105) increased from 1.32 (95% CI: 1.11, 1.54) to 2.02 (95% CI: 1.83, 2.22) with AAPC (2.6, 95% CI: -0.4, 5.7). At same period, the late-onset incidence increased from 3.54 (95% CI: 3.10, 3.97) to 9.14 (95% CI: 8.62, 9.66) with AAPC (6.1, 95% CI: 3.5, 8.8). Among early-onset CRC patients, age 40–49 has the highest rates and women in this age group has higher rate than men. Our national data showed a gradual increase in CRC incidence rates, which reflect the global concern of early-onset CRC. Further research is needed to understand the etiology of early-onset CRC. Primary health care providers must be alerted about the increasing rate of early-onset CRC. To reduce the future burden of the disease, initiating CRC screening before age 50 is warranted.

Sign in / Sign up

Export Citation Format

Share Document