Corrigendum to “Nanocrystalline hydroxyapatite doped with selenium oxyanions: A new material for potential biomedical applications” [Mater. Sci. Eng. C 39 (2014) 134–142]

Bone tissue engineering is constantly in need of new material development with improved biocompatibility or mechanical features closer to those of natural bone. Other important factors are the sustainability, cost, and origin of the natural precursors involved in the technological process. This study focused on two widely used polymers in tissue engineering, namely polylactic acid (PLA) and thermoplastic polyurethane (TPU), as well as bovine-bone-derived hydroxyapatite (HA) for the manufacturing of core-shell structures. In order to embed the ceramic particles on the polymeric filaments surface, the materials were introduced in an electrical oven at various temperatures and exposure times and under various pressing forces. The obtained core-shell structures were characterized in terms of morphology and composition, and a pull-out test was used to demonstrate the particles adhesion on the polymeric filaments structure. Thermal properties (modulated temperature and exposure time) and the pressing force’s influence upon HA particles’ insertion degree were evaluated. More to the point, the form variation factor and the mass variation led to the optimal technological parameters for the synthesis of core-shell materials for prospect additive manufacturing and regenerative medicine applications.

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Nanocrystalline hydroxyapatite doped with aluminium: A potential carrier for biomedical applications

Ceramics International ◽

10.1016/j.ceramint.2015.12.060 ◽

2016 ◽

Vol 42 (4) ◽

pp. 5304-5311 ◽

Cited By ~ 13

Author(s):

Tanaji V. Kolekar ◽

Nanasaheb D. Thorat ◽

Hemraj M. Yadav ◽

Veeresh T. Magalad ◽

Mahesh A. Shinde ◽

...

Keyword(s):

Biomedical Applications ◽

Nanocrystalline Hydroxyapatite

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Poly(aspartic acid) Biohydrogel as the Base of a New Hybrid Conducting Material

International Journal of Molecular Sciences ◽

10.3390/ijms222313165 ◽

2021 ◽

Vol 22 (23) ◽

pp. 13165

Author(s):

Adrián Fontana-Escartín ◽

Guillem Ruano ◽

Fiorella M. Silva ◽

Francesc Estrany ◽

Jordi Puiggalí ◽

...

Keyword(s):

Electrochemical Properties ◽

Aspartic Acid ◽

Conducting Polymer ◽

Biomedical Applications ◽

Polymer Network ◽

Conducting Material ◽

Electrically Conductive ◽

Biodegradable Hydrogel ◽

New Material ◽

Cross Linker

In the present study, a composite made of conducting polymer, poly(3,4-ethylenedioxythiophene) (PEDOT), and a biodegradable hydrogel of poly(aspartic acid) (PASP) were electrochemically interpenetrated with poly(hydroxymethyl-3,4-ethylenedioxythiophene) (PHMeDOT) to prepare a new interpenetrated polymer network (IPN). Different cross-linker and PEDOT MPs contents, as well as different electropolymerization times, were studied to optimize the structural and electrochemical properties. The properties of the new material, being electrically conductive, biocompatible, bioactive, and biodegradable, make it suitable for possible uses in biomedical applications.

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Nanostructured Hydrogels by Blend Electrospinning of Polycaprolactone/Gelatin Nanofibers

Nanomaterials ◽

10.3390/nano8070551 ◽

2018 ◽

Vol 8 (7) ◽

pp. 551 ◽

Cited By ~ 9

Author(s):

Lode Daelemans ◽

Iline Steyaert ◽

Ella Schoolaert ◽

Camille Goudenhooft ◽

Hubert Rahier ◽

...

Keyword(s):

Biomedical Applications ◽

Composition Range ◽

Fiber Diameter ◽

Polymer Concentration ◽

Solvent System ◽

High Potential ◽

Concentration Addition ◽

New Materials ◽

New Material ◽

Nanofibrous Membranes

Nanofibrous membranes based on polycaprolactone (PCL) have a large potential for use in biomedical applications but are limited by the hydrophobicity of PCL. Blend electrospinning of PCL with other biomedical suited materials, such as gelatin (Gt) allows for the design of better and new materials. This study investigates the possibility of blend electrospinning PCL/Gt nanofibrous membranes which can be used to design a range of novel materials better suited for biomedical applications. The electrospinnability and stability of PCL/Gt blend nanofibers from a non-toxic acid solvent system are investigated. The solvent system developed in this work allows good electrospinnable emulsions for the whole PCL/Gt composition range. Uniform bead-free nanofibers can easily be produced, and the resulting fiber diameter can be tuned by altering the total polymer concentration. Addition of small amounts of water stabilizes the electrospinning emulsions, allowing the electrospinning of large and homogeneous nanofibrous structures over a prolonged period. The resulting blend nanofibrous membranes are analyzed for their composition, morphology, and homogeneity. Cold-gelling experiments on these novel membranes show the possibility of obtaining water-stable PCL/Gt nanofibrous membranes, as well as nanostructured hydrogels reinforced with nanofibers. Both material classes provide a high potential for designing new material applications.

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SYNTHESIS AND CHARACTERIZATION OF COMPOSITES BASED ON HYDROXYAPATITE NANOPARTICLES AND CHITOSAN EXTRACTED FROM SHELLS OF THE FRESHWATER CRAB Potamon algeriense

Progress on Chemistry and application of Chitin and its Derivatives ◽

10.15259/pcacd.25.010 ◽

2020 ◽

Vol XXV ◽

pp. 132-142

Author(s):

Mohammed Lakrat ◽

Soufiane Fadlaoui ◽

Mohamed Aaddouz ◽

Ouahid El Asri ◽

Mohammed Melhaoui ◽

...

Keyword(s):

Tissue Engineering ◽

Bone Tissue Engineering ◽

Bone Tissue ◽

Biomedical Applications ◽

Freshwater Crab ◽

Hydroxyapatite Nanoparticles ◽

X Ray Diffraction ◽

X Ray ◽

Nanocrystalline Hydroxyapatite

Nanocrystalline hydroxyapatite (n-HAp), which has low crystallinity, has attracted great attention due to its similarity to the inorganic part of human bone. Therefore, many studies have focused on creating new formulations combining n-HAp with some biopolymers, such as chitosan, in order to imitate biological bone tissue. The importance of chitosan and its derivatives in biomedical applications has grown significantly in the last three decades due to its biodegradability and renewable source. Besides, chitosan and its derivatives present excellent biocompatibility and biofunctionality, which make them promising materials in bone tissue engineering. In the present study, the chitosan was, first, extracted from the shell of the freshwater crab species Potamon algeriense following demineralization, deproteinization, decolouration (raw chitin) and deacetylation (chitosan) steps. Then, a novel composite based on n-HAp and extracted chitosan (CTS) with varying chitosan contents, from 5% to 20% (w/w), was synthesized and characterized for potential application in tissue regeneration. The obtained composites were characterized using X-ray diffraction, Fourier transform infrared spectroscopy and thermogravimetric analysis. The precipitated n-HAp/CTS nanocomposites similar to natural bone are promising composites for bone tissue engineering applications.

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Alumina/Zirconia Micro/Nanocomposites: A New Material for Biomedical Applications with Superior Sliding Wear Resistance

Progress in Nanotechnology ◽

10.1002/9780470588260.ch6 ◽

2014 ◽

pp. 37-44

Author(s):

José F. Bartolomé ◽

Antonio H. De Aza ◽

Antonia Martín ◽

José Y. Pastor ◽

Javier Llorca ◽

...

Keyword(s):

Wear Resistance ◽

Biomedical Applications ◽

Sliding Wear ◽

New Material

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Sintering of Chitosan and Chitosan Composites

Volume 3: Design, Materials and Manufacturing, Parts A, B, and C ◽

10.1115/imece2012-86393 ◽

2012 ◽

Author(s):

Cynthia Brysch ◽

Eric Wold ◽

Francisco C. Robles Hernandez ◽

John F. Eberth

Keyword(s):

Mechanical Properties ◽

Carbon Nanostructures ◽

Biomedical Applications ◽

X Ray Diffraction ◽

Degradation Temperature ◽

Naturally Occurring ◽

New Material ◽

Sintering Conditions ◽

Temperature Exposure ◽

Chitosan Composite

Chitosan is a naturally-occurring polymer that is derived through the deacetylation of chitin. Chitin, found in the exoskeletons of invertebrates, is ubiquitous in nature and easily collected as waste and repurposed for a multitude of industrial and biomedical applications. Development of composites of chitosan and carbon are attractive due to their availability, compatibility, and mechanical properties. In the present work we construct a chitosan composite reinforced with 2 wt% carbon nanostructures using mechanical milling. The carbon nanostructures consist of amorphous carbon, graphene-like, and graphitic nanostructures synthesized by mechanical exfoliation. We demonstrate that the mechanical properties of this composite material can be altered by varying the sintering conditions. Preliminary thermal analysis showed a degradation temperature around 220 ± 5 °C but this was also influenced by the duration of temperature exposure. The material was strengthened by adding carbon nano-composites and through sintering. Better sintering conditions occurred at lower temperatures and shorter times. The new material properties are characterized by means of mechanical testing, electron microscopy, Raman spectroscopy, and X-ray diffraction.

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Properties of Porous Ti-35Nb-7Zr-5Ta Processed by the Spacer Method for Use in Biomedical Applications

Materials Science Forum ◽

10.4028/www.scientific.net/msf.591-593.224 ◽

2008 ◽

Vol 591-593 ◽

pp. 224-229 ◽

Cited By ~ 2

Author(s):

Elisa B. Taddei ◽

V.A.R. Henriques ◽

Cosme Roberto Moreira Silva ◽

Carlos Alberto Alves Cairo

Keyword(s):

Biomedical Applications ◽

Microstructural Characterization ◽

Complete Removal ◽

Bone Graft Substitute ◽

Strength Properties ◽

Metallic Material ◽

Space Holder ◽

Porous Ti ◽

New Material ◽

Highly Porous

Ti-35Nb-7Zr-5Ta alloy is a promising new material for a bone graft substitute with good strength properties and an elastic modulus closer to that of bone than any other metallic material. TNZT samples until 50 vol % porosity were manufactured using ‘‘space holder’’ technique and sintering methods. Irregular ammonium carbonate powders were used as a space holder material. Complete removal carbonate from the green compact was achieved by heating at 200 °C for 5 hours and subsequent sintering at 1600 °C, with heating rate of 10 °C/min. For the alloy microstructural characterization, scanning electron microscopy was used. Density was measured by Archimedes method. The results show that the blended elemental P/M process and the space holder technique are efficient for the obtainment of highly porous samples. Foams with porosities in the range between 10% and 50% could be reached.

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