scholarly journals Recent trends in biodegradable polyester Nanomaterials for Cancer therapy

2021 ◽  
pp. 112198
Author(s):  
Piyush Kumar Gupta ◽  
Rekha Gahtori ◽  
Kavitha Govarthanan ◽  
Vineeta Sharma ◽  
Sreenath Pappuru ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Biodegradable Polyester ◽  
Recent Trends

scholarly journals Antioxidants in Cancer Therapy: Recent Trends in Application of Nanotechnology for Enhanced Delivery

2020 ◽  
Vol 88 (1) ◽  
pp. 5 ◽  
Author(s):  
Hussein O. Ammar ◽  
Rehab N. Shamma ◽  
Rasha S. E. Elbatanony ◽  
Basma Khater
Keyword(s):  
Oxidative Stress ◽  
Cardiovascular Diseases ◽  
Cancer Therapy ◽  
Drug Concentration ◽  
Therapeutic Index ◽  
Tumor Tissues ◽  
Site Of Action ◽  
Anticancer Treatment ◽  
Recent Trends

Recently, the occurrence of cancer has significantly increased; it represents the second-most frequent cause of death after cardiovascular diseases. Many dietary antioxidants have shown large impact as effective agents for cancer prevention by reducing oxidative stress, which has been a part in the development of many diseases, including cancer. One of the obstacles in the delivery of antioxidant therapies into the required domain lies in the inadequate delivery of these agents to their intended site of action. Using nanotechnology in delivery of antioxidants leads to increased therapeutic index and higher drug concentration in tumor tissues, thus enhancing anticancer treatment. In this review, we discuss the role of different antioxidants in cancer therapy and their improved therapeutic effect through their formulation using nanotechnology.

Nanoparticles in Lung Cancer Therapy - Recent Trends

2015 ◽  
Author(s):  
Abhijit Bandyopadhyay ◽  
Tamalika Das ◽  
Sabina Yeasmin
Keyword(s):  
Lung Cancer ◽  
Cancer Therapy ◽  
Lung Cancer Therapy ◽  
Recent Trends

Recent trends in cancer therapy: A review on the current state of gene delivery

Life Sciences ◽  
2021 ◽  
Vol 269 ◽  
pp. 119087
Author(s):  
Esam Bashir Yahya ◽  
Amaal Mohammed Alqadhi
Keyword(s):  
Cancer Therapy ◽  
Gene Delivery ◽  
Current State ◽  
Recent Trends

Recent trends in targeting miRNAs for cancer therapy

2020 ◽  
Vol 72 (12) ◽  
pp. 1732-1749 ◽  
Author(s):  
Vandit Shah ◽  
Jigna Shah
Keyword(s):  
Cancer Therapy ◽  
Recent Trends

Recent Trends in In Situ Enzyme-Activatable Prodrugs for Targeted Cancer Therapy

2020 ◽  
Vol 31 (4) ◽  
pp. 1012-1024
Author(s):  
In-Cheol Sun ◽  
Hong Yeol Yoon ◽  
Dong-Kwon Lim ◽  
Kwangmeyung Kim
Keyword(s):  
Cancer Therapy ◽  
Targeted Cancer Therapy ◽  
Recent Trends

Anticancer s-Triazine Derivatives: A Synthetic Attribute

2020 ◽  
Vol 17 (8) ◽  
pp. 904-921
Author(s):  
Sonika Jain ◽  
Pankaj Kumar Jain ◽  
Shalu Sain ◽  
Dharma Kishore ◽  
Jaya Dwivedi
Keyword(s):  
Cell Proliferation ◽  
Drug Discovery ◽  
Cancer Therapy ◽  
Antitumor Activity ◽  
Review Article ◽  
Bioactive Molecules ◽  
Antitumor Activities ◽  
Triazine Derivatives ◽  
Recent Trends

1, 3, 5-Triazine (s-Triazine) is a versatile nucleus to design and develop potent bioactive molecules for drug discovery, particularly in cancer therapy. The aim of this review is to present the most recent trends in the field of synthetic strategies made for functionalized triazine derivatives active against cell proliferation. This review article covers the synthesis of aryl methylamino, morpholino, triamino substituted triazines, antimitotic agents coupled triazines and many more. Many 1,3,5- triazine derivatives, both hetero-fused and uncondensed, have shown remarkable antitumor activities. We have highlighted various derivatives with 1, 3, 5-triazine core targeting different kinases with an aim to help researchers for developing new 1, 3, 5-triazine derived compounds for antitumor activity.

scholarly journals Tumor Angiogenesis and Anti-Angiogenic Strategies for Cancer Treatment

2019 ◽  
Vol 9 (1) ◽  
pp. 84 ◽  
Author(s):  
Raluca Ioana Teleanu ◽  
Cristina Chircov ◽  
Alexandru Mihai Grumezescu ◽  
Daniel Mihai Teleanu
Keyword(s):  
Cancer Therapy ◽  
Tumor Growth ◽  
Cancer Treatment ◽  
Blood Vessels ◽  
Tumor Angiogenesis ◽  
The Body ◽  
Tumor Vascularization ◽  
Recent Trends

Angiogenesis is the process through which novel blood vessels are formed from pre-existing ones and it is involved in both physiological and pathological processes of the body. Furthermore, tumor angiogenesis is a crucial factor associated with tumor growth, progression, and metastasis. In this manner, there has been a great interest in the development of anti-angiogenesis strategies that could inhibit tumor vascularization. Conventional approaches comprise the administration of anti-angiogenic drugs that target and block the activity of proangiogenic factors. However, as their efficacy is still a matter of debate, novel strategies have been focusing on combining anti-angiogenic agents with chemotherapy or immunotherapy. Moreover, nanotechnology has also been investigated for the potential of nanomaterials to target and release anti-angiogenic drugs at specific sites. The aim of this paper is to review the mechanisms involved in angiogenesis and tumor vascularization and provide an overview of the recent trends in anti-angiogenic strategies for cancer therapy.

Biodegradable polyester neuroprostheses promote the reconnection of separated peripheral nerve stubs

1992 ◽  
Vol 50 (2) ◽  
pp. 1094-1095
Author(s):  
Beverly L. Giammara ◽  
Jennifer S. Stevenson ◽  
Peggy E. Yates ◽  
Robert H. Gunderson ◽  
Jacob S. Hanker
Keyword(s):  
Image Analysis ◽  
Basement Membrane ◽  
Periodic Acid ◽  
Light And Electron Microscopy ◽  
Computer Assisted ◽  
Type Iii Collagen ◽  
Image Analysis System ◽  
Biodegradable Polyester ◽  
Adult Rats ◽  
Type Iv

An 11mm length of sciatic nerve was removed from 10 anesthetized adult rats and replaced by a biodegradable polyester Vicryl™ mesh sleeve which was then injected with the basement membrane gel, Matrigel™. It was noted that leg sensation and movement were much improved after 30 to 45 days and upon sacrifice nerve reconnection was noted in all animals. Epoxy sections of the repaired nerves were compared with those of the excised segments by the use of a variation of the PAS reaction, the PATS reaction, developed in our laboratories for light and electron microscopy. This microwave-accelerated technique employs periodic acid, thiocarbohydrazide and silver methenamine. It stains basement membrane or Type IV collagen brown and type III collagen (reticulin), axons, Schwann cells, endoneurium and perineurium black. Epoxy sections of repaired and excised nerves were also compared by toluidine blue (tb) staining. Comparison of the sections of control and repaired nerves was done by computer-assisted microscopic image analysis using an Olympus CUE-2 Image Analysis System.

Multifunctional metal–organic framework heterostructures for enhanced cancer therapy

2021 ◽  
Author(s):  
Jintong Liu ◽  
Jing Huang ◽  
Lei Zhang ◽  
Jianping Lei
Keyword(s):  
Cancer Therapy ◽  
General Principle ◽  
Biomedical Applications ◽  
Metal Organic Framework ◽  
Metal Organic ◽  
Functional Modulation ◽  
Organic Framework

We review the general principle of the design and functional modulation of nanoscaled MOF heterostructures, and biomedical applications in enhanced therapy.

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