Malignant lesion of clear cells: A diagnostic challenge of an unusual presentation mimicking a benign lesion

Oral Oncology ◽  
2021 ◽  
Vol 122 ◽  
pp. 105538
Author(s):  
Maria Gabriela Rolim Silveira Sá ◽  
Henrique Bemfica de Farias Freitas ◽  
Martinho Campolina Rebello Horta ◽  
Marcelo Ferreira Cardoso Pinto ◽  
Lorenzo Duarte Testolin ◽  
...  
Keyword(s):  
Benign Lesion ◽  
Malignant Lesion ◽  
Unusual Presentation ◽  
Diagnostic Challenge ◽  
Clear Cells

scholarly journals Imaging Features of Renal Capsule Leiomyoma on Contrast-Enhanced Ultrasonography: A Case Report

2017 ◽  
Vol 33 (6) ◽  
pp. 514-519 ◽  
Author(s):  
José Andrade Moura Neto ◽  
Ana Flavia Perpétuo de Souza ◽  
José Hermógenes Rocco Suassuna ◽  
Luiz Carlos Aguiar Vaz ◽  
Nordeval Cavalcante Araújo
Keyword(s):  
Transplant Recipient ◽  
Kidney Transplant Recipient ◽  
Malignant Lesion ◽  
Immunosuppressive Drugs ◽  
Imaging Features ◽  
Diagnostic Challenge ◽  
Contrast Enhanced ◽  
Increased Risk ◽  
Contrast Enhanced Ultrasonography ◽  
Histopathologic Analysis

Leiomyomas of the kidney are rare, mostly occurring in adults as incidental findings, and are a diagnostic challenge. In a renal transplant recipient population, an increased risk of tumors is observed due to the effect of immunosuppressive drugs. A differential diagnosis between leiomyomas and other malignant lesions is not possible with current imaging methods. This report presents a case of a native kidney capsular leiomyoma in a kidney transplant recipient and highlights the features of computed tomography and contrast-enhanced ultrasound (CEUS), along with the histopathologic analysis. The CEUS and quantification studies are helpful in demonstrating the vascularization pattern of the renal capsular leiomyoma. This entity appearing with chronic kidney disease can resemble a renal cell carcinoma, in an otherwise healthy kidney. In this case, CEUS was useful for diagnosing the vascularization of the renal mass, although the pattern of intense vascularization could be diagnostically misleading, implying a malignant lesion. However, the pattern of enhancement due to CEUS showed no peculiarities that indicated histopathologic diagnosis.

scholarly journals Ovarian tumors: Incidence, histological type of lesions and treatment in pediatric age group

2021 ◽  
Vol 75 ◽  
pp. 292-296
Author(s):  
Patrycja Sosnowska-Sienkiewicz ◽  
Piotr Nogal ◽  
Dawid Gawron ◽  
Korneliusz Wójcik ◽  
Danuta Januszkiewicz-Lewandowska ◽  
...  
Keyword(s):  
Clinical Symptoms ◽  
Malignant Tumors ◽  
Histopathological Examination ◽  
Tumor Staging ◽  
Benign Lesion ◽  
Mature Teratoma ◽  
Malignant Lesion ◽  
Ovarian Tumors ◽  
Histological Type ◽  
Tumor Type

Background: The aim of this study was to evaluate the incidence and histological type of lesions affecting the ovaries and to analyze employed methods of invasive treatment. Materials&Methods: Medical records of patients who were treated surgically for ovarian tumors in the years 2015 -2019 were reviewed. The study group was comprised of 31 female patients. Results: During 5 years time, there were 31 girls in the age from 3 months to 17 years hospitalized in the department. The mean age was 11 years. Histopathological examination was performed in all of these cases. 12 patients were diagnosed with malignant lesion, 19 with benign lesion. The most commonly diagnosed malignant tumors were a dysgerminoma and a mixed germ cell tumor. In the group of benign lesions, the most frequent tumor type was mature teratoma. The first occurring symptom was abdominal pain. Some of the lesions were diagnosed accidentally during ultrasonography. The diagnostics was expanded depending on the size of the tumor, staging and clinical condition of the patient. All the patients were treated surgically, 16 of them underwent laparoscopic surgery. Torsion of the ovary or oviduct was observed in 3 cases. Chemotherapy was introduced in 8 cases as complementary treatment. Conclusions: The most commonly diagnosed tumor was mature teratoma. Ultrasonography is the most frequent method of the ovaries’ examination. Ovarian lesions are characterized by non-specific clinical symptoms, which is associated with prevalent incidental detection during ultrasonography.

scholarly journals A study of gastrointestinal tumors at kathmandu medical college teaching hospital

2018 ◽  
Vol 8 (1) ◽  
pp. 1285-1288
Author(s):  
Sailesh Bahadur Pradhan ◽  
Binita Pradhan ◽  
Sailuja Maharjan ◽  
Prabin Bikram Thapa
Keyword(s):  
Gastrointestinal Tract ◽  
Teaching Hospital ◽  
Histopathological Examination ◽  
Benign Lesion ◽  
Malignant Lesion ◽  
College Teaching ◽  
Age Group ◽  
Benign Lesions ◽  
Cross Sectional ◽  
Medical College

Background: Gastrointestinal tract tumour is responsible for more cancers and death than any other cancers.  The tumour in GIT include the tumour of the Oral cavity, Esophagus, Stomach, Colon, Rectum, Liver, Gallbladder, Pancreas and Biliary tree.Materials and methods: A cross sectional study was carried out among all the gastrointestinal tract tumours specimens received for histopathological examination in between January 2016 to June 2017 in Department of Pathology, Kathmandu Medical College Teaching Hospital. All tumors diagnosed either benign or malignant were included in this study. Ethical clearance was obtained from the Institutional Review Committee in KMCTH.Results: Colorectum was found to be the most commonly involved site for malignant lesion comprising 40.2% among all malignant lesions followed by stomach comprising 28.6%. Malignancy was found to be more prevalent among male with M:F ratio of 1.6:1 in colorectal region and 1.4:1 in stomach cancers. Regarding benign lesions (polyps), rectum was found to be the commonest site (57.5%), followed by colon (20.0%) and stomach, the least common site.Malignant lesions were more common among the age group of 51-60 years (37.66%) with 70.13% above 50 years. Benign lesions were also found to be the most common above 50 years comprising 40.0 percent.Conclusion: Rectum & colon was found to be the most commonly involved site for both malignant and benign lesion. Malignancy is more prevalent among male and common above 50 years of age. However, malignant cases noted in the adult age group are a matter of great concern.

scholarly journals Cornual pregnancy-an unusual site of pregnancy: a case report and literature review

2019 ◽  
Vol 10 (1) ◽  
pp. 64-67
Author(s):  
Tanzeem S Chowdhury ◽  
Homaira Hasan ◽  
TA Chowdhury
Keyword(s):  
Ectopic Pregnancy ◽  
Uterine Cavity ◽  
Uterine Wall ◽  
Unusual Presentation ◽  
Cornual Pregnancy ◽  
Diagnostic Challenge ◽  
Unusual Site ◽  
Rare Type ◽  
Interstitial Pregnancy ◽  
Gestational Sac

Ectopic pregnancy is a condition where gestational sac is located outside the uterine cavity. Cornual pregnancy, also known as interstitial pregnancy, is a rare type of ectopic pregnancy that develops in the interstitial portion of the fallopian tube and invades through the uterine wall. It poses great diagnostic challenge because of its unusual presentation and late diagnosis. Cornual pregnancy, if not diagnosed early, may present with massive and uncontrollable bleeding even leading to maternal death. We hereby report an unusual presentation of cornual pregnancy which was diagnosed and subsequently managed successfully. Birdem Med J 2020; 10(1): 64-67

scholarly journals Evaluation of Breast Masses by Sonomammography and X-ray Mammography in Correlation with Histopathological Findings

2017 ◽  
Vol 03 (01) ◽  
pp. 003-006
Author(s):  
Namita Chandak ◽  
Rajasbala Dhande
Keyword(s):  
Breast Imaging ◽  
Benign Lesion ◽  
Tertiary Care ◽  
Malignant Lesion ◽  
Diagnostic Study ◽  
Care Hospital ◽  
X Ray ◽  
Sebaceous Cyst ◽  
Breast Infection

Abstract Introduction: Breast lumps are common presenting complaints in the female surgical outpatient department, which are due to varied breast pathologies. Breast infection most commonly affects women aged 18 to 50 years; in this age group, it can be divided into lactational and nonlactational infections. The process can affect the skin overlying the breast, where it can be a primary event, or it may be secondary to a lesion, such as sebaceous cyst or hidradenitis suppurativa. Aim: The aim of this article was to find out sonographic features of benign and malignant masses and correlate X-ray mammography and sonographic findings with histopathology with classification of all breast lesions according to the breast imaging reporting and data system final assessment categories (BI-RADS) (mammography). Materials and methods: This was a prospective diagnostic study conducted on 50 female patients from September 2015 to August 2016 in the Department of Radiodiagnosis in a tertiary care hospital. Results: In benign lesion, 24 (48%) of the patients had fibroadenoma, 2% intraductal papilloma, and 1 (2%) each had galactocele and tubercular abscess; in malignant lesion, 23 (46%) had ductal malignancy. Conclusion: The ultrasound features are helpful in differentiating benign from malignant masses. Classification of the lesions according to BI-RADS helps to improve the management of lesions.

scholarly journals Role of triple assessment modalities in diagnosis of palpable breast lump

2018 ◽  
Vol 6 (10) ◽  
pp. 3435
Author(s):  
Ashwinkumar S. Gadhvi ◽  
Udit I. Gadhvi ◽  
Dhaval A. Bhimani ◽  
Darshil K. Rajgor
Keyword(s):  
Benign Lesion ◽  
Malignant Lesion ◽  
Breast Disease ◽  
Breast Lump ◽  
Size Number ◽  
Life Saving ◽  
Triple Assessment ◽  
Palpable Breast ◽  
Sensitivity Specificity

Background: One fourth of women suffer from breast disease in their lifetime. Carcinoma of breast is the second most common cancer in the world. Timely and accurate diagnosis of breast lump with early intervention can be life saving. There are various modalities for the diagnosis of breast lump such as USG, FNAC and Mammography, MRI etc. but none of them is perfect. There are numerous reports suggesting that if the results of clinical assessment, mammography and FNAC are all combined, the diagnostic accuracy is nearly 100%. Furthermore, these techniques also provide information about tumor size, number, extent and grade preoperatively.Methods: Study was randomized, prospective, observational and longitudinal including 100 patients, selected according to inclusion criteria.Results: The sensitivity, specificity and accuracy of triple test in present study were 98.68%, 87.5%, and 96% respectively. Out of 100, 76 patients were confirmed as having benign lesion and 24 patients having malignant lesion by histopathology examination.Conclusions: Results of triple assessment are same as the results by histopathology examination in majority of cases. It is highly accurate, can be used as a confirmatory diagnostic tool for breast lump, thus there is no need to perform diagnostic open biopsy for breast lump.

scholarly journals A clinicopathological study of masses of nasal cavity paranasal sinuses and nasopharynx

2017 ◽  
Vol 3 (2) ◽  
pp. 253
Author(s):  
Rajat Sharma ◽  
Dimple Sahni ◽  
Kuljeet Uppal ◽  
Rajeev Gupta ◽  
Gifty Singla
Keyword(s):  
Nasal Cavity ◽  
Paranasal Sinuses ◽  
Benign Lesion ◽  
Malignant Lesion ◽  
Histopathological Diagnosis ◽  
Radiological Findings ◽  
Female Ratio ◽  
Road Map ◽  
Neoplastic Lesion ◽  
Nasopharyngeal Masses

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">A variety of inflammatory, non neoplastic and neoplastic masses involving nasal cavity, paranasal sinuses and nasopharynx are commonly encountered in ENT clinics. The objective was to study the demographic profile, clinical presentation, radiological findings and its correlation with the histopathological findings of masses of nasal cavity, paranasal sinuses and nasopharynx. </span></p><p class="abstract"><strong>Methods:</strong> <span lang="EN-IN">The study was conducted on patients having sinonasal and nasopharyngeal masses admitted in dept of ENT, GMC, Patiala from August 2014 to July 2016. The study was designed to evaluate demographic distribution, clinicopathological features, radiological findings of sinonasal and nasopharyngeal masses and to evaluate the correlation of clinical and radiological findings with histopathological diagnosis.  </span></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">Analysis of 50 cases of masses in nasal cavity, paranasal sinuses and nasopharynx was done. Male to female ratio was 1.38:1. The commonest site was nasal cavity followed by paranasal sinuses. Nasal polyp was the most common non-neoplastic lesion. Among the neoplastic lesions studied, inverted papilloma was the most common benign lesion and squamous cell carcinoma was the most common malignant lesion observed. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">For proper evaluation of sinonasal and nasopharyngeal masses, clinical, radiological and histopathological evaluation should be done in all patients. Although radiology provides a road map to endoscopic surgeons for any existing or impending complications but histopathology always gives a confirmatory diagnosis.</span></p>

scholarly journals Sclerosing Hemangioma of the Lung and Concurrent Sarcoidosis of the Hilar Lymph Nodes

2016 ◽  
Vol 1 (3) ◽  
pp. 173-178
Author(s):  
Soichi Takekawa ◽  
Takehiko Abe ◽  
Yoshikei Miura ◽  
Hidenori Shinjo ◽  
Kenji Kawakura ◽  
...  
Keyword(s):  
Lymph Nodes ◽  
Thoracoscopic Surgery ◽  
Benign Lesion ◽  
Malignant Lesion ◽  
Sclerosing Hemangioma ◽  
Medicine Research ◽  
Pulmonary Sclerosing Hemangioma ◽  
Contrast Enhanced Ct ◽  
Imaging Results ◽  
Enhanced Ct

Objective: To present chest radiographs, CT and pathological fndings of pulmonary sclerosing hemangioma with concurrent sarcoidosis. To review the literatures regarding lung cancer and associated sarcoidosis and/or sclerosing hemangioma.Materials and Methods: A 50 year-old female patient was screened for health at human dock at Preventive Medicine Research Center of our institution, and a rounded nodule, measuring about 15 mm in diameter, was found in the left lower lung feld medially. Non-enhanced CT showed a round nodule at the left cardiac border. The patient was sent to a clinic of our institution.Results: The patient was further studied by contrast enhanced CT (CECT), which showed marked increase of CT value to 91.8 HU from 50.1 HU on non-enhanced CT. It was difcult to di?erentiate a benign lesion from malignant lesion. CECT also showed enlarged hilar and mediastinal lymph nodes. Cytology at the time of bronchoscopy revealed Class 3 at the left B5b bronchus. Partial resection of the lingual was carried out by video-assisted thoracoscopic surgery. Biopsy of the left hilar nodes (#10, #11) at the same time revealed sarcoidosis.Conclusion: A rare case of pulmonary screlosing hemangioma and concurrent sarcoidosis was reported with imaging results and pathological proof.

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