Risk factors for intramammary infection in meat- and pelt producing ewes with clinically healthy udders

2021 ◽  
pp. 106595
Author(s):  
Ylva Persson ◽  
Katarina Gustafsson ◽  
Maya Hoffman ◽  
Ann-Kristin Nyman ◽  
Lennart Söderquist ◽  
...  
Keyword(s):  
Risk Factors ◽  
Intramammary Infection

Risk factors of S. aureus intramammary infection in pre partum dairy heifers under grazing conditions and molecular characterization of isolates from heifers and cows

2020 ◽  
Vol 87 (1) ◽  
pp. 82-88
Author(s):  
Cecilia M. Camussone ◽  
Ana I. Molineri ◽  
Marcelo L. Signorini ◽  
Verónica E. Neder ◽  
Carlos A. Vitulich ◽  
...  
Keyword(s):  
Risk Factors ◽  
Staphylococcus Aureus ◽  
Management Practices ◽  
Molecular Level ◽  
Univariate Analysis ◽  
Multivariable Analysis ◽  
Cow Milk ◽  
Intramammary Infection ◽  
Dairy Heifers ◽  
Lactating Cows

AbstractThe aims of the research reported here were to identify potential risk factors associated with the presence of Staphylococcus aureus intramammary infection (IMI) in pre partum dairy heifers on 17 dairy farms from three provinces of Argentina and to characterize, at molecular level, isolates from those heifers and lactating cows from two selected herds. A total of 1474 heifers and 4878 lactating cows were studied. The prevalence of Staphylococcus aureus IMI in the heifers, heifers at quarter level and lactating cow mammary quarters was 14.41, 4.82, and 14.65%, respectively. Univariate analysis showed the key variables associated with S. aureus IMI presence in the heifers were: S. aureus IMI prevalence in cows of the lactating herd, the time calves stayed with their dam after birth, the calf rearing system, the place of rearing (own farm or other dairy farm) and fly control on the farm. None of the variables included in the multivariable analysis was associated with the presence of S. aureus IMI in the pre partum heifers, probably due to low variability among management practices used by the farms for rearing the heifer calves. At the molecular level, S. aureus isolates were grouped into three main PFGE clusters and several genotypes within the clusters. Isolates from mammary secretion of pre partum heifers and milk of lactating cows comprised different PFGE clusters in both herds, although two exceptions occurred. The absence of gene fnbpB, which codifies for a virulence factor protein involved in cell invasion by S. aureus, was significantly more frequent in pre partum heifer secretion isolates than in isolates from lactating cow milk. These results suggest that, under these management conditions, isolates from mammary secretions of pre partum heifers do not originate from the milk of lactating cows, but rather other sources to which the heifer is exposed.

scholarly journals Quarter- and cow-level risk factors for intramammary infection with coagulase-negative staphylococci species in Swiss dairy cows

2017 ◽  
Vol 100 (7) ◽  
pp. 5653-5663 ◽  
Author(s):  
C. Dolder ◽  
B.H.P. van den Borne ◽  
J. Traversari ◽  
A. Thomann ◽  
V. Perreten ◽  
...  
Keyword(s):  
Risk Factors ◽  
Dairy Cows ◽  
Coagulase Negative Staphylococci ◽  
Intramammary Infection

scholarly journals Risk factors associated with intramammary colonization with Mollicutes in dairy cattle from Southeast Brazil

2021 ◽  
Vol 51 (8) ◽  
Author(s):  
Ana Carolina Nunes de Morais ◽  
Danielle Regis Pires ◽  
Nathalie Costa da Cunha ◽  
Leandro dos Santos Machado ◽  
Michel Abdalla Helayel ◽  
...  
Keyword(s):  
Risk Factors ◽  
Rio De Janeiro ◽  
Dairy Herds ◽  
Chain Reaction ◽  
Chi Square ◽  
Intramammary Infection ◽  
Factors Associated ◽  
Southeast Brazil ◽  
Chi Square Test ◽  
Polymerase Chain

ABSTRACT: Bacteria of Mollicutes Class are associated with intramammary infection and decrease in milk production. This study investigated the occurrence of Mollicutes and elucidated their risk factors in dairy herds from Southeast Brazil. For this, milk samples from 387 lactation cows from Minas Gerais, Rio de Janeiro and São Paulo States were subjected to the polymerase chain reaction (PCR) to detect Mollicutes. Species of Mycoplasma were investigated in Mollicutes positive samples by PCR, including Mycoplasma bovis, M. alkalescens, M. bovigenitalium, M. bovirhinis, M. arginini and A. laidlawii. An epidemiological questionnaire was applied to collect data on possible risk factors, which were assessed using Pearson’s Chi-square test followed by odds ratio (P≤0.05). Mollicutes were reported in 21% (4/19) of the herds and 4% (16/387) of the animals, while 1% (5/387) were positive for M. bovis and 3% (11/387) for M. arginini. All samples were negative to the other agents. Herds with more than 150 animals [OR=3.51 (95% CI 1.11-11.08)], manual milking [OR=9.97 (95% CI 2.80-35.49)] and not-milking animals with mastitis last [OR=6.54 (95% CI 1.92-22.29)] were risk factors. The presence of these conditions may favor intramammary infection by Mollicutes in dairy herds from Southeast Brazil. This is the first report of M. bovis in Rio de Janeiro and M. arginini in the studied states.

Environmental and managerial risk factors of intramammary infection with coagulase-negative staphylococci in Ohio dairy herds

1992 ◽  
Vol 14 (1-2) ◽  
pp. 129-142 ◽  
Author(s):  
Paul C. Bartlett ◽  
Gay Y. Miller ◽  
Susan E. Lance ◽  
Lawrence E. Heider ◽  
Clyde R. Anderson
Keyword(s):  
Risk Factors ◽  
Dairy Herds ◽  
Coagulase Negative Staphylococci ◽  
Intramammary Infection ◽  
Managerial Risk

Elevated level of circulatory sTLT1 induces inflammation through SYK/MEK/ERK signalling in coronary artery disease

2019 ◽  
Vol 133 (22) ◽  
pp. 2283-2299
Author(s):  
Apabrita Ayan Das ◽  
Devasmita Chakravarty ◽  
Debmalya Bhunia ◽  
Surajit Ghosh ◽  
Prakash C. Mandal ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Chronic Inflammation ◽  
Ex Vivo ◽  
Human Subjects ◽  
Critical Role ◽  
Atherosclerotic Cardiovascular Disease ◽  
Tnf Α ◽  
Artery Disease

Abstract The role of inflammation in all phases of atherosclerotic process is well established and soluble TREM-like transcript 1 (sTLT1) is reported to be associated with chronic inflammation. Yet, no information is available about the involvement of sTLT1 in atherosclerotic cardiovascular disease. Present study was undertaken to determine the pathophysiological significance of sTLT1 in atherosclerosis by employing an observational study on human subjects (n=117) followed by experiments in human macrophages and atherosclerotic apolipoprotein E (apoE)−/− mice. Plasma level of sTLT1 was found to be significantly (P<0.05) higher in clinical (2342 ± 184 pg/ml) and subclinical cases (1773 ± 118 pg/ml) than healthy controls (461 ± 57 pg/ml). Moreover, statistical analyses further indicated that sTLT1 was not only associated with common risk factors for Coronary Artery Disease (CAD) in both clinical and subclinical groups but also strongly correlated with disease severity. Ex vivo studies on macrophages showed that sTLT1 interacts with Fcɣ receptor I (FcɣRI) to activate spleen tyrosine kinase (SYK)-mediated downstream MAP kinase signalling cascade to activate nuclear factor-κ B (NF-kB). Activation of NF-kB induces secretion of tumour necrosis factor-α (TNF-α) from macrophage cells that plays pivotal role in governing the persistence of chronic inflammation. Atherosclerotic apoE−/− mice also showed high levels of sTLT1 and TNF-α in nearly occluded aortic stage indicating the contribution of sTLT1 in inflammation. Our results clearly demonstrate that sTLT1 is clinically related to the risk factors of CAD. We also showed that binding of sTLT1 with macrophage membrane receptor, FcɣR1 initiates inflammatory signals in macrophages suggesting its critical role in thrombus development and atherosclerosis.

Sign in / Sign up

Export Citation Format

Share Document