PtCu Nanocages with Superior Tetra-enzyme Mimics for Colorimetric Sensing and Fluorescent Sensing Dehydroepiandrosterone

2021 ◽  
pp. 130905
Author(s):  
Huiyi Yang ◽  
Qiyi He ◽  
Junkang Pan ◽  
Mingxia Lin ◽  
Zhiting Lao ◽  
...  
2017 ◽  
Vol 53 (91) ◽  
pp. 12306-12308 ◽  
Author(s):  
Shazia Mumtaz ◽  
Li-Sheng Wang ◽  
Syed Zajif Hussain ◽  
Muhammad Abdullah ◽  
Zille Huma ◽  
...  

Colorimetric sensing of bacteria using dopamine-functionalized iron oxide nanoparticles.


2021 ◽  
Vol 28 ◽  
Author(s):  
Hayati Filik ◽  
Asiye Aslıhan Avan ◽  
Zehra Füsun Tokatlı

: Nanomedicine is an arising field that exploits nanotechnology concepts for pioneered therapy and diagnostics. Colorimetric sensors for tumor markers have displayed interesting benefits compared to conventional systems in clinical laboratory diagnosis. Colorimetric immunoassay based approaches show up-and-coming results since the goal cancer marker is determined with high sensitivity but without the utilize of advanced/expensive techniques through an effortless optical color change. Also, colorimetric biosensor has the potential to detect proteins in biological fluids swiftly with high sensitivity, and they are anticipated to play a progressively serious role in tumor diagnosis. We are reviewed (covering the period 2015–2020) various studies performed based on colorimetric sensing strategy using nanostructured materials (highly efficient enzyme mimics, artificial enzymes or nanozymes) in the detection of various tumor antigens in biological fluids are reviewed. Specifically, we highlight the recent progress and efforts in the construction of colorimetric immunosensors. Colorimetric immunosensors can be roughly divided into two main categories: transition metal nanozyme-based sensing and noble metal nanozyme-based sensings.


2020 ◽  
Author(s):  
Ian Mallov ◽  
Fiona Jeeva ◽  
Chris Caputo

Food is often wasted due to real or perceived concerns about preservation and shelf life. Thus, precise, accurate and consumer-friendly methods of indicating whether food is safe for consumers are drawing great interest. The colorimetric sensing of biogenic amines released as food degrades is a potential way of determining the quality of the food. Herein, we report the use of genipin, a naturally occurring iridoid, as a dual colorimetric sensor for both oxygen and biogenic amines. Immobilization of genipin in edible calcium alginate beads demonstrates that it is a capable sensor for amine vapors and can be immobilized in a non-toxic, food-friendly matrix.


2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Pojchanun Kanitthamniyom ◽  
Pei Yun Hon ◽  
Aiwu Zhou ◽  
Mohammad Yazid Abdad ◽  
Zhi Yun Leow ◽  
...  

AbstractCarbapenemase-producing Enterobacteriaceae (CPE) are a group of drug-resistant Gram-negative pathogens that are classified as a critical threat by the World Health Organization (WHO). Conventional methods of detecting antibiotic-resistant pathogens do not assess the resistance mechanism and are often time-consuming and laborious. We have developed a magnetic digital microfluidic (MDM) platform, known as MDM Carba, for the identification of CPE by measuring their ability to hydrolyze carbapenem antibiotics. MDM Carba offers the ability to rapidly test CPE and reduce the amount of reagents used compared with conventional phenotypic testing. On the MDM Carba platform, tests are performed in droplets that function as reaction chambers, and fluidic operations are accomplished by manipulating these droplets with magnetic force. The simple droplet-based magnetic fluidic operation allows easy system automation and simplified hands-on operation. Because of the unique “power-free” operation of MDM technology, the MDM Carba platform can also be operated manually, showing great potential for point-of-care testing in resource-limited settings. We tested 27 bacterial isolates on the MDM Carba platform, and the results showed sensitivity and specificity that were comparable to those of the widely used Carba NP test. MDM Carba may shorten the overall turnaround time for CPE identification, thereby enabling more timely clinical decisions for better clinical outcomes. MDM Carba is a technological platform that can be further developed to improve diagnostics for other types of antibiotic resistance with minor modifications.


2021 ◽  
Vol 40 ◽  
pp. 101964
Author(s):  
Noor S. Shah ◽  
Jibran Iqbal ◽  
Murtaza Sayed ◽  
Sajid Rauf ◽  
Munirah D. Albaqami ◽  
...  

Nanomaterials ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1869
Author(s):  
A K M Mashud Alam ◽  
Donovan Jenks ◽  
George A. Kraus ◽  
Chunhui Xiang

Organophosphate (OP) compounds, a family of highly hazardous chemical compounds included in nerve agents and pesticides, have been linked to more than 250,000 annual deaths connected to various chronic diseases. However, a solid-state sensing system that is able to be integrated into a clothing system is rare in the literature. This study aims to develop a nanofiber-based solid-state polymeric material as a soft sensor to detect OP compounds present in the environment. Esters of polydiacetylene were synthesized and incorporated into a cellulose acetate nanocomposite fibrous assembly developed with an electrospinning technique, which was then hydrolyzed to generate more hydroxyl groups for OP binding. Scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FT-IR), Instron® tensile tester, contact angle analyzer, and UV–Vis spectroscopy were employed for characterizations. Upon hydrolysis, polydiacetylene esters in the cellulosic fiber matrix were found unaffected by hydrolysis treatment, which made the composites suitable for OP sensing. Furthermore, the nanofibrous (NF) composites exhibited tensile properties suitable to be used as a textile material. Finally, the NF composites exhibited colorimetric sensing of OP, which is visible to the naked eye. This research is a landmark study toward the development of OP sensing in a protective clothing system.


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